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Loss of Androgen Receptor-Dependent Growth Suppression by Prostate Cancer Cells Can Occur Independently from Acquiring Oncogenic Addiction to Androgen Receptor Signaling.
Published in:
PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011475
By:
- D'Antonio, Jason M.;
- Griend, Donald J. Vander;
- Antony, Lizamma;
- Ndikuyeze, George;
- Dalrymple, Susan L.;
- Koochekpour, Shahriar;
- Isaacs, John T.
Publication type:
Article
Detection and Quantification of the Evolution Dynamics of Apoptosis Using the PET Voltage Sensor <sup>18</sup>F-Fluorobenzyl Triphenyl Phosphonium.
Published in:
Journal of Nuclear Medicine, 2009, v. 50, n. 5, p. 774, doi. 10.2967/jnumed.108.061283
By:
- Madar, Igal;
- Yi Huang;
- Ravert, Hayden;
- Dalrymple, Susan L.;
- Davidson, Nancy E.;
- Isaacs, John T.;
- Dannals, Robert F.;
- Frost, J. James
Publication type:
Article
A hemi‐spleen injection model of liver metastasis for prostate cancer.
Published in:
Prostate, 2020, v. 80, n. 14, p. 1263, doi. 10.1002/pros.24055
By:
- Simons, Brian W.;
- Dalrymple, Susan;
- Rosen, Marc;
- Zheng, Lei;
- Brennen, W. Nathaniel
Publication type:
Article
Androgen receptor (AR) suppresses normal human prostate epithelial cell proliferation via AR/β-catenin/TCF-4 complex inhibition of c-MYC transcription.
Published in:
Prostate, 2014, v. 74, n. 11, p. 1118, doi. 10.1002/pros.22828
By:
- Antony, Lizamma;
- van der Schoor, Freek;
- Dalrymple, Susan L.;
- Isaacs, John T.
Publication type:
Article
Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate.
Published in:
Prostate, 2014, v. 74, n. 8, p. 805, doi. 10.1002/pros.22803
By:
- Regter, Sietze;
- Hedayati, Mohammad;
- Zhang, Yonggang;
- Zhou, Haoming;
- Dalrymple, Susan;
- Koch, Cameron J.;
- Isaacs, John T.;
- DeWeese, Theodore L.
Publication type:
Article
Of mice and men-warning: Intact versus castrated adult male mice as xenograft hosts are equivalent to hypogonadal versus abiraterone treated aging human males, respectively.
Published in:
Prostate, 2013, v. 73, n. 12, p. 1316, doi. 10.1002/pros.22677
By:
- Sedelaar, J.P. Michiel;
- Dalrymple, Susan S.;
- Isaacs, John T.
Publication type:
Article
Adaptive auto-regulation of androgen receptor provides a paradigm shifting rationale for bipolar androgen therapy (BAT) for castrate resistant human prostate cancer.
Published in:
Prostate, 2012, v. 72, n. 14, p. 1491, doi. 10.1002/pros.22504
By:
- Isaacs, John T.;
- D'Antonio, Jason M.;
- Chen, Shuangling;
- Antony, Lizamma;
- Dalrymple, Susan P.;
- Ndikuyeze, Georges H.;
- Luo, Jun;
- Denmeade, Samuel R.
Publication type:
Article
Tasquinimod prevents the angiogenic rebound induced by fractionated radiation resulting in an enhanced therapeutic response of prostate cancer xenografts.
Published in:
Prostate, 2012, v. 72, n. 6, p. 638, doi. 10.1002/pros.21467
By:
- Dalrymple, Susan L.;
- Becker, Robyn E.;
- Zhou, Haoming;
- DeWeese, Theodore L.;
- Isaacs, John T.
Publication type:
Article
The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts.
Published in:
Prostate, 2007, v. 67, n. 7, p. 790, doi. 10.1002/pros.20573
By:
- Dalrymple, Susan L.;
- Becker, Robin E.;
- Isaacs, John T.
Publication type:
Article
PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor.
Published in:
Prostate, 2006, v. 66, n. 12, p. 1329, doi. 10.1002/pros.20483
By:
- Ivan V. Litvinov;
- Lizamma Antony;
- Susan L. Dalrymple;
- Robyn Becker;
- Linzhao Cheng;
- John T. Isaacs
Publication type:
Article
Identification of ABR‐215050 as lead second generation quinoline‐3‐carboxamide anti‐angiogenic agent for the treatment of prostate cancer.
Published in:
Prostate, 2006, v. 66, n. 16, p. 1768, doi. 10.1002/pros.20509
By:
- John T. Isaacs;
- Roberto Pili;
- David Z. Qian;
- Susan L. Dalrymple;
- Jason B. Garrison;
- Natasha Kyprianou;
- Anders Björk;
- Anders Olsson;
- Tomas Leanderson
Publication type:
Article
Dissociation between androgen responsiveness for malignant growth vs. expression of prostate specific differentiation markers PSA, hK2, and PSMA in human prostate cancer models.
Published in:
Prostate, 2003, v. 54, n. 4, p. 249, doi. 10.1002/pros.10199
By:
- Denmeade, Samuel R.;
- Sokoll, Lori J.;
- Dalrymple, Susan;
- Rosen, D. Marc;
- Gady, Alyssa M.;
- Bruzek, Debra;
- Ricklis, Rebecca M.;
- Isaacs, John T.
Publication type:
Article
Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy.
Published in:
Science Translational Medicine, 2012, v. 4, n. 140, p. 1, doi. 10.1126/scitranslmed.3003886
By:
- Denmeade, Samuel R.;
- Mhaka, Annastasiah M.;
- Rosen, D. Marc;
- Brennen, W. Nathaniel;
- Dalrymple, Susan;
- Dach, Ingrid;
- Olesen, Claus;
- Gurel, Bora;
- DeMarzo, Angelo M.;
- Wilding, George;
- Carducci, Michael A.;
- Dionne, Craig A.;
- Møller, Jesper V.;
- Nissen, Poul;
- Christensen, S. Brøgger;
- Isaacs, John T.
Publication type:
Article
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Published in:
Prostate, 2024, v. 84, n. 10, p. 909, doi. 10.1002/pros.24707
By:
- Jasmine, Sumer;
- Mandl, Adel;
- Krueger, Timothy E. G.;
- Dalrymple, Susan L.;
- Antony, Lizamma;
- Dias, Jennifer;
- Celatka, Cassandra A.;
- Tapper, Amy E.;
- Kleppe, Maria;
- Kanayama, Mayuko;
- Jing, Yuezhou;
- Speranzini, Valentina;
- Wang, Yuzhuo Z.;
- Luo, Jun;
- Trock, Bruce J.;
- Denmeade, Samuel R.;
- Carducci, Michael A.;
- Mattevi, Andrea;
- Rienhoff, Hugh Y.;
- Isaacs, John T.
Publication type:
Article
Targeting the fibroblast growth factor pathway in molecular subtypes of castration‐resistant prostate cancer.
Published in:
Prostate, 2024, v. 84, n. 1, p. 100, doi. 10.1002/pros.24630
By:
- Labrecque, Mark P.;
- Brown, Lisha G.;
- Coleman, Ilsa M.;
- Nguyen, Holly M.;
- Dalrymple, Susan;
- Brennen, W. Nathaniel;
- Isaacs, John T.;
- Li, Dapei;
- Lakely, Bryce;
- DeLucia, Diana C.;
- Lee, John K.;
- Schweizer, Michael T.;
- Lin, Daniel W.;
- Corey, Eva;
- Nelson, Peter S.;
- Morrissey, Colm
Publication type:
Article
Third generation quinoline‐3‐carboxamide transcriptional disrupter of HDAC4, HIF‐1α, and MEF‐2 signaling for metastatic castration‐resistant prostate cancer.
Published in:
Prostate, 2023, v. 83, n. 15, p. 1470, doi. 10.1002/pros.24606
By:
- Isaacs, John T.;
- Dalrymple, Susan L.;
- Antony, Lizamma;
- Marc Rosen, David;
- Coleman, Ilsa M.;
- Nelson, Peter S.;
- Kostova, Maya;
- Murray, Iain A.;
- Perdew, Gary H.;
- Denmeade, Samuel R.;
- Akinboye, Emmanuel S.;
- Brennen, W. Nathaniel
Publication type:
Article

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