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Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 9, p. 3063, doi. 10.1172/JCI62636
By:
- Butovsky, Oleg;
- Siddiqui, Shafiuddin;
- Gabriely, Galina;
- Lanser, Amanda J.;
- Dake, Ben;
- Murugaiyan, Gopal;
- Doykan, Camille E.;
- Wu, Pauline M.;
- Gali, Reddy R.;
- Iyer, Lakshmanan K.;
- Lawson, Robert;
- Berry, James;
- Krichevsky, Anna M.;
- Cudkowicz, Merit E.;
- Weiner, Howard L.
Publication type:
Article
Safety and Tolerability of SRX246, a Vasopressin 1a Antagonist, in Irritable Huntington's Disease Patients—A Randomized Phase 2 Clinical Trial.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 11, p. 3682, doi. 10.3390/jcm9113682
By:
- Brownstein, Michael J.;
- Simon, Neal G.;
- Long, Jeffrey D.;
- Yankey, Jon;
- Maibach, Hilda T.;
- Cudkowicz, Merit;
- Coffey, Christopher;
- Conwit, Robin A.;
- Lungu, Codrin;
- Anderson, Karen E.;
- Hersch, Steven M.;
- Ecklund, Dixie J.;
- Damiano, Eve M.;
- Itzkowitz, Debra E.;
- Lu, Shifang;
- Chase, Marianne K.;
- Shefner, Jeremy M.;
- McGarry, Andrew;
- Thornell, Brenda;
- Gladden, Catherine
Publication type:
Article
Crowdsourced analysis of clinical trial data to predict amyotrophic lateral sclerosis progression.
Published in:
Nature Biotechnology, 2015, v. 33, n. 1, p. 51, doi. 10.1038/nbt.3051
By:
- Küffner, Robert;
- Zach, Neta;
- Norel, Raquel;
- Hawe, Johann;
- Schoenfeld, David;
- Wang, Liuxia;
- Li, Guang;
- Fang, Lilly;
- Mackey, Lester;
- Hardiman, Orla;
- Cudkowicz, Merit;
- Sherman, Alexander;
- Ertaylan, Gokhan;
- Grosse-Wentrup, Moritz;
- Hothorn, Torsten;
- van Ligtenberg, Jules;
- Macke, Jakob H;
- Meyer, Timm;
- Schölkopf, Bernhard;
- Tran, Linh
Publication type:
Article
Identification of gene fusions associated with amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2024, v. 69, n. 4, p. 477, doi. 10.1002/mus.28043
By:
- Raghav, Yogindra;
- Dilliott, Allison A.;
- Petrozziello, Tiziana;
- Kim, Spencer E.;
- Berry, James D.;
- Cudkowicz, Merit E.;
- Vakili, Khashayar;
- Fraenkel, Ernest;
- Farhan, Sali M. K.;
- Sadri‐Vakili, Ghazaleh
Publication type:
Article
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis.
Published in:
Nature Medicine, 2011, v. 17, n. 12, p. 1652, doi. 10.1038/nm.2579
By:
- Cudkowicz, Merit;
- Bozik, Michael E;
- Ingersoll, Evan W;
- Miller, Robert;
- Mitsumoto, Hiroshi;
- Shefner, Jeremy;
- Moore, Dan H;
- Schoenfeld, David;
- Mather, James L;
- Archibald, Donald;
- Sullivan, Mary;
- Amburgey, Craig;
- Moritz, Juliet;
- Gribkoff, Valentin K
Publication type:
Article
Safety, Pharmacokinetic, and Functional Effects of the Nogo-A Monoclonal Antibody in Amyotrophic Lateral Sclerosis: A Randomized, First-In-Human Clinical Trial.
Published in:
PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097803
By:
- Meininger, Vincent;
- Pradat, Pierre-François;
- Corse, Andrea;
- Al-Sarraj, Safa;
- Rix Brooks, Benjamin;
- Caress, James B.;
- Cudkowicz, Merit;
- Kolb, Stephen J.;
- Lange, Dale;
- Leigh, P. Nigel;
- Meyer, Thomas;
- Milleri, Stefano;
- Morrison, Karen E.;
- Orrell, Richard W.;
- Peters, Gary;
- Rothstein, Jeffrey D.;
- Shefner, Jeremy;
- Lavrov, Arseniy;
- Williams, Nicola;
- Overend, Phil
Publication type:
Article
Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061177
By:
- Berry, James D.;
- Shefner, Jeremy M.;
- Conwit, Robin;
- Schoenfeld, David;
- Keroack, Myles;
- Felsenstein, Donna;
- Krivickas, Lisa;
- David, William S.;
- Vriesendorp, Francine;
- Pestronk, Alan;
- Caress, James B.;
- Katz, Jonathan;
- Simpson, Ericka;
- Rosenfeld, Jeffrey;
- Pascuzzi, Robert;
- Glass, Jonathan;
- Rezania, Kourosh;
- Rothstein, Jeffrey D.;
- Greenblatt, David J.;
- Cudkowicz, Merit E.
Publication type:
Article
A High-Density Genome-Wide Association Screen of Sporadic ALS in US Veterans.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032768
By:
- Kwee, Lydia Coulter;
- Yutao Liu;
- Haynes, Carol;
- Gibson, Jason R.;
- Stone, Annjanette;
- Schichman, Steven A.;
- Kamel, Freya;
- Nelson, Lorene M.;
- Topol, Barbara;
- Van Den Eeden, Stephen K.;
- Tanner, Caroline M.;
- Cudkowicz, Merit E.;
- Grasso, Daniela L.;
- Lawson, Robert;
- Muralidhar, Sumitra;
- Oddone, Eugene Z.;
- Schmidt, Silke;
- Hauser, Michael A.
Publication type:
Article
Survival analyses from the CENTAUR trial in amyotrophic lateral sclerosis: Evaluating the impact of treatment crossover on outcomes.
Published in:
Muscle & Nerve, 2022, v. 66, n. 2, p. 136, doi. 10.1002/mus.27569
By:
- Paganoni, Sabrina;
- Watkins, Claire;
- Cawson, Matthew;
- Hendrix, Suzanne;
- Dickson, Samuel P.;
- Knowlton, Newman;
- Timmons, Jamie;
- Manuel, Machelle;
- Cudkowicz, Merit
Publication type:
Article
Phase 2B randomized controlled trial of NP001 in amyotrophic lateral sclerosis: Pre‐specified and post hoc analyses.
Published in:
Muscle & Nerve, 2022, v. 66, n. 1, p. 39, doi. 10.1002/mus.27511
By:
- Miller, Robert G.;
- Zhang, Rongzhen;
- Bracci, Paige M.;
- Azhir, Ari;
- Barohn, Richard;
- Bedlack, Richard;
- Benatar, Michael;
- Berry, James D.;
- Cudkowicz, Merit;
- Kasarskis, Edward J.;
- Mitsumoto, Hiroshi;
- Manousakis, Georgios;
- Walk, David;
- Oskarsson, Bjorn;
- Shefner, Jeremy;
- McGrath, Michael S.
Publication type:
Article
A randomized placebo‐controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2022, v. 65, n. 3, p. 291, doi. 10.1002/mus.27472
By:
- Cudkowicz, Merit E.;
- Lindborg, Stacy R.;
- Goyal, Namita A.;
- Miller, Robert G.;
- Burford, Matthew J.;
- Berry, James D.;
- Nicholson, Katharine A.;
- Mozaffar, Tahseen;
- Katz, Jonathan S.;
- Jenkins, Liberty J.;
- Baloh, Robert H.;
- Lewis, Richard A.;
- Staff, Nathan P.;
- Owegi, Margaret A.;
- Berry, Donald A.;
- Gothelf, Yael;
- Levy, Yossef S.;
- Aricha, Revital;
- Kern, Ralph Z.;
- Windebank, Anthony J.
Publication type:
Article
Gold Coast diagnostic criteria: Implications for ALS diagnosis and clinical trial enrollment.
Published in:
Muscle & Nerve, 2021, v. 64, n. 5, p. 532, doi. 10.1002/mus.27392
By:
- Vucic, Steve;
- Ferguson, Toby A.;
- Cummings, Catherine;
- Hotchkin, Michael T.;
- Genge, Angela;
- Glanzman, Robert;
- Roet, Kasper C. D.;
- Cudkowicz, Merit;
- Kiernan, Matthew C.
Publication type:
Article
Tocilizumab is safe and tolerable and reduces C‐reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients.
Published in:
Muscle & Nerve, 2021, v. 64, n. 3, p. 309, doi. 10.1002/mus.27339
By:
- Milligan, Carol;
- Atassi, Nazem;
- Babu, Suma;
- Barohn, Richard J.;
- Caress, James B.;
- Cudkowicz, Merit E.;
- Evora, Armineuza;
- Hawkins, Gregory A.;
- Wosiski‐Kuhn, Marlena;
- Macklin, Eric A.;
- Shefner, Jeremy M.;
- Simmons, Zachary;
- Bowser, Robert P.;
- Ladha, Shafeeq S.
Publication type:
Article
Amyotrophic lateral sclerosis care and research in the United States during the COVID-19 pandemic: Challenges and opportunities.
Published in:
2020
By:
- Andrews, Jinsy A.;
- Berry, James D.;
- Baloh, Robert H.;
- Carberry, Nathan;
- Cudkowicz, Merit E.;
- Dedi, Brixhilda;
- Glass, Jonathan;
- Maragakis, Nicholas J.;
- Miller, Timothy M.;
- Paganoni, Sabrina;
- Rothstein, Jeffrey D.;
- Shefner, Jeremy M.;
- Simmons, Zachary;
- Weiss, Michael D.;
- Bedlack, Richard S.
Publication type:
journal article
Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS.
Published in:
2020
By:
- Goyal, Namita A.;
- Berry, James D.;
- Windebank, Anthony;
- Staff, Nathan P.;
- Maragakis, Nicholas J.;
- Berg, Leonard H.;
- Genge, Angela;
- Miller, Robert;
- Baloh, Robert H.;
- Kern, Ralph;
- Gothelf, Yael;
- Lebovits, Chaim;
- Cudkowicz, Merit;
- van den Berg, Leonard H
Publication type:
journal article
Mexiletine for muscle cramps in amyotrophic lateral sclerosis: A randomized, double-blind crossover trial.
Published in:
2018
By:
- Oskarsson, Björn;
- Moore, Dan;
- Mozaffar, Tahseen;
- Ravits, John;
- Wiedau‐Pazos, Martina;
- Parziale, Nicholas;
- Joyce, Nanette C.;
- Mandeville, Ross;
- Goyal, Namita;
- Cudkowicz, Merit E.;
- Weiss, Michael;
- Miller, Robert G.;
- McDonald, Craig M.;
- Wiedau-Pazos, Martina
Publication type:
journal article
Urate levels predict survival in amyotrophic lateral sclerosis: Analysis of the expanded Pooled Resource Open-Access ALS clinical trials database.
Published in:
2018
By:
- Paganoni, Sabrina;
- Nicholson, Katharine;
- Chan, James;
- Shui, Amy;
- Schoenfeld, David;
- Sherman, Alexander;
- Berry, James;
- Cudkowicz, Merit;
- Atassi, Nazem;
- for the Pooled Resource Open‐Access ALS Clinical Trials Consortium;
- Pooled Resource Open-Access ALS Clinical Trials Consortium
Publication type:
journal article
Developing multidisciplinary clinics for neuromuscular care and research.
Published in:
2017
By:
- Paganoni, Sabrina;
- Nicholson, Katie;
- Leigh, Fawn;
- Swoboda, Kathryn;
- Chad, David;
- Drake, Kristin;
- Haley, Kellen;
- Cudkowicz, Merit;
- Berry, James D.
Publication type:
journal article
Vitamin D levels are associated with gross motor function in amyotrophic lateral sclerosis.
Published in:
2017
By:
- Paganoni, Sabrina;
- Macklin, Eric A.;
- Karam, Chafic;
- Yu, Hong;
- Gonterman, Fernando;
- Fetterman, K. Ashley;
- Cudkowicz, Merit;
- Berry, James;
- Wills, Anne‐Marie
Publication type:
journal article
Fixed dynamometry is more sensitive than vital capacity or ALS rating scale.
Published in:
2017
By:
- Andres, Patricia L.;
- Allred, Margaret (Peggy);
- Stephens, Helen E.;
- Proffitt Bunnell, Mary;
- Siener, Catherine;
- Macklin, Eric A.;
- Haines, Travis;
- English, Robert A.;
- Fetterman, Katherine A.;
- Kasarskis, Edward J.;
- Florence, Julaine;
- Simmons, Zachary;
- Cudkowicz, Merit E.
Publication type:
journal article
Reply.
Published in:
2015
By:
- Paganoni, Sabrina;
- Schoenfeld, David;
- Shui, Amy;
- Cudkowicz, Merit;
- Miller, Timothy M.
Publication type:
Letter
Pre-morbid type 2 diabetes mellitus is not a prognostic factor in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2015, v. 52, n. 3, p. 339, doi. 10.1002/mus.24688
By:
- Paganoni, Sabrina;
- Hyman, Theodore;
- Shui, Amy;
- Allred, Peggy;
- Harms, Matthew;
- Liu, Jingxia;
- Maragakis, Nicholas;
- Schoenfeld, David;
- Yu, Hong;
- Atassi, Nazem;
- Cudkowicz, Merit;
- Miller, Timothy M.
Publication type:
Article
7-T MRI of the spinal cord can detect lateral corticospinal tract abnormality in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2013, v. 47, n. 5, p. 760, doi. 10.1002/mus.23720
By:
- Cohen‐Adad, Julien;
- Zhao, Wei;
- Keil, Boris;
- Ratai, Eva‐Maria;
- Triantafyllou, Christina;
- Lawson, Robert;
- Dheel, Christina;
- Wald, Lawrence L.;
- Rosen, Bruce R.;
- Cudkowicz, Merit;
- Atassi, Nazem
Publication type:
Article
Developing normalized strength scores for neuromuscular research.
Published in:
Muscle & Nerve, 2013, v. 47, n. 2, p. 177, doi. 10.1002/mus.23516
By:
- Andres, Patricia L.;
- English, Robert;
- Mendoza, Michelle;
- Florence, Julaine;
- Malkus, Elizabeth;
- Schierbecker, Jeanine;
- Siener, Catherine;
- Malspeis, Susan;
- Schoenfeld, David A.;
- Munsat, Theodore L.;
- Cudkowicz, Merit E.
Publication type:
Article
What does body mass index measure in amyotrophic lateral sclerosis and why should we care?
Published in:
Muscle & Nerve, 2012, v. 45, n. 4, p. 612, doi. 10.1002/mus.22338
By:
- Paganoni, Sabrina;
- Deng, Jing;
- Jaffa, Matthew;
- Cudkowicz, Merit E.;
- Wills, Anne-Marie
Publication type:
Article
Validation of a new strength measurement device for amyotrophic lateral sclerosis clinical trials.
Published in:
Muscle & Nerve, 2012, v. 45, n. 1, p. 81, doi. 10.1002/mus.22253
By:
- Andres, Patricia L.;
- Skerry, Linda M.;
- Munsat, Theodore L.;
- Thornell, Brenda J.;
- Szymonifka, Jackie;
- Schoenfeld, David A.;
- Cudkowicz, Merit E.
Publication type:
Article
Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2011, v. 44, n. 1, p. 20, doi. 10.1002/mus.22114
By:
- Paganoni, Sabrina;
- Deng, Jing;
- Jaffa, Matthew;
- Cudkowicz, Merit E.;
- Wills, Anne-Marie
Publication type:
Article
Discovery and verification of amyotrophic lateral sclerosis biomarkers by proteomics.
Published in:
Muscle & Nerve, 2010, v. 42, n. 1, p. 104, doi. 10.1002/mus.21683
By:
- Ryberg, Henrik;
- An, Jiyan;
- Darko, Samuel;
- Lustgarten, Jonathan Llyle;
- Jaffa, Matt;
- Gopalakrishnan, Vanathi;
- Lacomis, David;
- Cudkowicz, Merit;
- Bowser, Robert
Publication type:
Article
Lyme disease serology in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2009, v. 40, n. 4, p. 626, doi. 10.1002/mus.21438
By:
- Qureshi, Muddasir;
- Bedlack, Richard S.;
- Cudkowicz, Merit E.
Publication type:
Article
Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2008, v. 38, n. 1, p. 837, doi. 10.1002/mus.21059
By:
- Cudkowicz, Merit E.;
- Shefner, Jeremy M.;
- Simpson, Elizabeth;
- Grasso, Daniela;
- Yu, Hong;
- Zhang, Hui;
- Shui, Amy;
- Schoenfeld, David;
- Brown, Robert H.;
- Wieland, Scott;
- Barber, Jack R.
Publication type:
Article
Comparison of incremental with multipoint MUNE methods in transgenic ALS mice.
Published in:
2002
By:
- Shefner, Jeremy M.;
- Cudkowicz, Merit E.;
- Brown, Robert H.;
- Brown, Robert H Jr
Publication type:
journal article
Cerebrospinal fluid levels of F<sub>2</sub>-isoprostanes in patients with neurodegenerative diseases.
Published in:
Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 2, p. 165, doi. 10.1016/S0009-9236(99)80190-8
By:
- Morrow, Jason D.;
- Jackson Roberts, L.;
- Montine, Thomas J.;
- Flint Beal, M.;
- Cudkowicz, Merit E.;
- O'Donnell, Heather
Publication type:
Article
Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.914017
By:
- Pun, Frank W.;
- Liu, Bonnie Hei Man;
- Long, Xi;
- Leung, Hoi Wing;
- Leung, Geoffrey Ho Duen;
- Mewborne, Quinlan T.;
- Gao, Junli;
- Shneyderman, Anastasia;
- Ozerov, Ivan V.;
- Wang, Ju;
- Ren, Feng;
- Aliper, Alexander;
- Bischof, Evelyne;
- Izumchenko, Evgeny;
- Guan, Xiaoming;
- Zhang, Ke;
- Lu, Bai;
- Rothstein, Jeffrey D.;
- Cudkowicz, Merit E.;
- Zhavoronkov, Alex
Publication type:
Article
Safety and Efficacy of Topiramate in Individuals With Cryptogenic Sensory Peripheral Neuropathy With Metabolic Syndrome: The TopCSPN Randomized Clinical Trial.
Published in:
JAMA Neurology, 2023, v. 80, n. 12, p. 1334, doi. 10.1001/jamaneurol.2023.3711
By:
- Smith, A. Gordon;
- Singleton, J. Robinson;
- Aperghis, Adrienne;
- Coffey, Christopher S.;
- Creigh, Peter;
- Cudkowicz, Merit;
- Conwit, Robin;
- Ecklund, Dixie;
- Fedler, Janel K.;
- Gudjonsdottir, Anna;
- Hauer, Peter;
- Herrmann, David N.;
- Kearney, Marianne;
- Kissel, John;
- Klingner, Elizabeth;
- Quick, Adam;
- Revere, Cathy;
- Stino, Amro
Publication type:
Article
Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers: A Review.
Published in:
JAMA Neurology, 2022, v. 79, n. 12, p. 1312, doi. 10.1001/jamaneurol.2022.3282
By:
- Shefner, Jeremy M.;
- Bedlack, Richard;
- Andrews, Jinsy A.;
- Berry, James D.;
- Bowser, Robert;
- Brown, Robert;
- Glass, Jonathan D.;
- Maragakis, Nicholas J.;
- Miller, Timothy M.;
- Rothstein, Jeffrey D.;
- Cudkowicz, Merit E.
Publication type:
Article
Seven-Year Experience From the National Institute of Neurological Disorders and Stroke–Supported Network for Excellence in Neuroscience Clinical Trials.
Published in:
JAMA Neurology, 2020, v. 77, n. 6, p. 755, doi. 10.1001/jamaneurol.2020.0367
By:
- Cudkowicz, Merit;
- Chase, Marianne K.;
- Coffey, Christopher S.;
- Ecklund, Dixie J.;
- Thornell, Brenda J.;
- Lungu, Codrin;
- Mahoney, Katy;
- Gutmann, Laurie;
- Shefner, Jeremy M.;
- Staley, Kevin J.;
- Bosch, Michael;
- Foster, Eric;
- Long, Jeffrey D.;
- Bayman, Emine O.;
- Torner, James;
- Yankey, Jon;
- Peters, Richard;
- Huff, Trevis;
- Conwit, Robin A.;
- Shinnar, Shlomo
Publication type:
Article
The Role of Environmental Toxins in Amyotrophic Lateral Sclerosis Risk.
Published in:
JAMA Neurology, 2016, v. 73, n. 7, p. 779, doi. 10.1001/jamaneurol.2016.1038
By:
- Cragg, Jacquelyn J.;
- Cudkowicz, Merit E.;
- Weisskopf, Marc G.
Publication type:
Article
Cortical Hyperexcitability in Amyotrophic Lateral Sclerosis.
Published in:
JAMA Neurology, 2015, v. 72, n. 11, p. 1235, doi. 10.1001/jamaneurol.2015.2197
By:
- Wainger, Brian J.;
- Cudkowicz, Merit E.
Publication type:
Article
Cromolyn sodium delays disease onset and is neuroprotective in the SOD1<sup>G93A</sup> Mouse Model of amyotrophic lateral sclerosis.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-53982-w
By:
- Granucci, Eric J.;
- Griciuc, Ana;
- Mueller, Kaly A.;
- Mills, Alexandra N.;
- Le, Hoang;
- Dios, Amanda M.;
- McGinty, Danielle;
- Pereira, Joao;
- Elmaleh, David;
- Berry, James D.;
- Paganoni, Sabrina;
- Cudkowicz, Merit E.;
- Tanzi, Rudolph E.;
- Sadri-Vakili, Ghazaleh
Publication type:
Article
Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models.
Published in:
2018
By:
- McCampbell, Alex;
- Cole, Tracy;
- Wegener, Amy J.;
- Tomassy, Giulio S.;
- Setnicka, Amy;
- Farley, Brandon J.;
- Schoch, Kathleen M.;
- Hoye, Mariah L.;
- Shabsovich, Mark;
- Linhong Sun;
- Yi Luo;
- Mingdi Zhang;
- Sai Thankamony;
- Salzman, David W.;
- Cudkowicz, Merit;
- Graham, Danielle L.;
- Bennett, C. Frank;
- Kordasiewicz, Holly B.;
- Swayze, Eric E.;
- Miller, Timothy M.
Publication type:
journal article
Analysis of sodium phenylbutyrate and taurursodiol survival effect in ALS using external controls.
Published in:
Annals of Clinical & Translational Neurology, 2023, v. 10, n. 12, p. 2297, doi. 10.1002/acn3.51915
By:
- Paganoni, Sabrina;
- Quintana, Melanie;
- Sherman, Alexander V.;
- Vestrucci, Matteo;
- Wu, Yuehui;
- Timmons, Jamie;
- Cudkowicz, Merit
Publication type:
Article
A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS.
Published in:
Annals of Clinical & Translational Neurology, 2022, v. 9, n. 1, p. 50, doi. 10.1002/acn3.51491
By:
- Katz, Jonathan S.;
- Rothstein, Jeffrey D.;
- Cudkowicz, Merit E.;
- Genge, Angela;
- Oskarsson, Björn;
- Hains, Avis B.;
- Chen, Chen;
- Galanter, Joshua;
- Burgess, Braydon L.;
- Cho, William;
- Kerchner, Geoffrey A.;
- Yeh, Felix L.;
- Ghosh, Arundhati Sengupta;
- Cheeti, Sravanthi;
- Brooks, Logan;
- Honigberg, Lee;
- Couch, Jessica A.;
- Rothenberg, Michael E.;
- Brunstein, Flavia;
- Sharma, Khema R.
Publication type:
Article
Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis.
Published in:
Annals of Clinical & Translational Neurology, 2018, v. 5, n. 12, p. 1522, doi. 10.1002/acn3.671
By:
- Nicholson, Katharine;
- Chan, James;
- Macklin, Eric A.;
- Levine‐Weinberg, Mark;
- Breen, Christopher;
- Bakshi, Rachit;
- Grasso, Daniela L.;
- Wills, Anne‐Marie;
- Jahandideh, Samad;
- Taylor, Albert A.;
- Beaulieu, Danielle;
- Ennist, David L.;
- Andronesi, Ovidiu;
- Ratai, Eva‐Maria;
- Schwarzschild, Michael A.;
- Cudkowicz, Merit;
- Paganoni, Sabrina
Publication type:
Article
Long‐term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS.
Published in:
Annals of Clinical & Translational Neurology, 2018, v. 5, n. 6, p. 730, doi. 10.1002/acn3.567
By:
- Goutman, Stephen A.;
- Brown, Morton B.;
- Glass, Jonathan D.;
- Boulis, Nicholas M.;
- Johe, Karl;
- Hazel, Tom;
- Cudkowicz, Merit;
- Atassi, Nazem;
- Borges, Lawrence;
- Patil, Parag G.;
- Sakowski, Stacey A.;
- Feldman, Eva L.
Publication type:
Article
Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid.
Published in:
Brain Pathology, 2022, v. 32, n. 2, p. 1, doi. 10.1111/bpa.13035
By:
- Petrozziello, Tiziana;
- Amaral, Ana C.;
- Dujardin, Simon;
- Farhan, Sali M. K.;
- Chan, James;
- Trombetta, Bianca A.;
- Kivisäkk, Pia;
- Mills, Alexandra N.;
- Bordt, Evan A.;
- Kim, Spencer E.;
- Dooley, Patrick M.;
- Commins, Caitlin;
- Connors, Theresa R.;
- Oakley, Derek H.;
- Ghosal, Anubrata;
- Gomez‐Isla, Teresa;
- Hyman, Bradley T.;
- Arnold, Steven E.;
- Spires‐Jones, Tara;
- Cudkowicz, Merit E.
Publication type:
Article
Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis.
Published in:
Annals of Neurology, 2023, v. 94, n. 3, p. 547, doi. 10.1002/ana.26714
By:
- Quintana, Melanie;
- Saville, Benjamin R.;
- Vestrucci, Matteo;
- Detry, Michelle A.;
- Chibnik, Lori;
- Shefner, Jeremy;
- Berry, James D.;
- Chase, Marianne;
- Andrews, Jinsy;
- Sherman, Alexander V.;
- Yu, Hong;
- Drake, Kristin;
- Cudkowicz, Merit;
- Paganoni, Sabrina;
- Macklin, Eric A.;
- Macklin, Eric;
- Hayden, Douglas;
- Lai, PoYing;
- Donahue, Rachel;
- Marion, Joseph
Publication type:
Article
Antibody Response to HML‐2 May Be Protective in Amyotrophic Lateral Sclerosis.
Published in:
Annals of Neurology, 2022, v. 92, n. 5, p. 782, doi. 10.1002/ana.26466
By:
- Garcia‐Montojo, Marta;
- Simula, Elena Rita;
- Fathi, Saeed;
- McMahan, Cynthia;
- Ghosal, Anubrata;
- Berry, James D.;
- Cudkowicz, Merit;
- Elkahloun, Abdel;
- Johnson, Kory;
- Norato, Gina;
- Jensen, Peter;
- James, Tony;
- Sechi, Leonardo A.;
- Nath, Avindra
Publication type:
Article
Regulatory Approval in ALS; When Is a Single Study Enough?
Published in:
Annals of Neurology, 2022, v. 91, n. 6, p. 737, doi. 10.1002/ana.26371
By:
- Cudkowicz, Merit E.;
- Shefner, Jeremy M.
Publication type:
Article
Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development.
Published in:
Annals of Neurology, 2022, v. 91, n. 2, p. 165, doi. 10.1002/ana.26285
By:
- Paganoni, Sabrina;
- Berry, James D.;
- Quintana, Melanie;
- Macklin, Eric;
- Saville, Benjamin R.;
- Detry, Michelle A.;
- Chase, Marianne;
- Sherman, Alexander V.;
- Yu, Hong;
- Drake, Kristin;
- Andrews, Jinsy;
- Shefner, Jeremy;
- Chibnik, Lori B.;
- Vestrucci, Matteo;
- Cudkowicz, Merit E.;
- Saville, Ben;
- Chibnik, Lori;
- Bind, Marie Abele;
- Chan, James;
- Locatelli, Eduardo
Publication type:
Article
Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke.
Published in:
2019
By:
- Lyden, Patrick;
- Pryor, Kent E.;
- Coffey, Christopher S.;
- Cudkowicz, Merit;
- Conwit, Robin;
- Jadhav, Ashutosh;
- Sawyer, Robert N.;
- Claassen, Jan;
- Adeoye, Opeolu;
- Song, Shlee;
- Hannon, Peter;
- Rost, Natalia S.;
- Hinduja, Archana;
- Torbey, Michel;
- Lee, Jin‐Moo;
- Benesch, Curtis;
- Rippee, Michael;
- Rymer, Marilyn;
- Froehler, Michael T.;
- Clarke Haley, E.
Publication type:
journal article

Found: 76