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The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1183, doi. 10.3390/ijms21041183
By:
- Lodge, Katharine M.;
- Cowburn, Andrew S.;
- Li, Wei;
- Condliffe, Alison M.
Publication type:
Article
Cardiovascular adaptation to hypoxia and the role of peripheral resistance.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.28755
By:
- Cowburn, Andrew S.;
- Macias, David;
- Summers, Charlotte;
- Chilvers, Edwin R.;
- Johnson, Randall S.
Publication type:
Article
Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045933
By:
- Juss, Jatinder K.;
- Hayhoe, Richard P.;
- Owen, Charles E.;
- Bruce, Ian;
- Walmsley, Sarah R.;
- Cowburn, Andrew S.;
- Kulkarni, Suhasini;
- Boyle, Keith B.;
- Stephens, Len;
- Hawkins, Phillip T.;
- Chilvers, Edwin R.;
- Condliffe, Alison M.;
- Benarafa, Charaf
Publication type:
Article
Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease.
Published in:
2022
By:
- Lodge, Katharine M.;
- Vassallo, Arlette;
- Bin Liu;
- Merete Long;
- Zhen Tong;
- Newby, Paul R.;
- Agha-Jaffar, Danya;
- Paschalaki, Koralia;
- Green, Clara E.;
- Belchamber, Kylie B. R.;
- Ridger, Victoria C.;
- Stockley, Robert A.;
- Sapey, Elizabeth;
- Summers, Charlotte;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.;
- Wei Li;
- Condliffe, Alison M.;
- Liu, Bin;
- Long, Merete
Publication type:
journal article
Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells.
Published in:
Respiratory Research, 2000, v. 1, p. 24, doi. 10.1186/rr8
By:
- Condliffe, Alison M.;
- Cadwallader, Karen A.;
- Walker, Trevor R.;
- Rintoul, Robert C.;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.
Publication type:
Article
Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 4, p. 423, doi. 10.1165/rcmb.2016-0193PS
By:
- Storisteanu, Daniel M. L.;
- Pocock, Joanna M.;
- Cowburn, Andrew S.;
- Juss, Jatinder K.;
- Nadesalingam, Angalee;
- Nizet, Victor;
- Chilvers, Edwin R.
Publication type:
Article
Granulocyte/Macrophage Colony-Stimulating Factor Causes a Paradoxical Increase in the BH3-Only Pro-Apoptotic Protein Bim in Human Neutrophils.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 44, n. 6, p. 879, doi. 10.1165/rcmb.2010-0101OC
By:
- Cowburn, Andrew S.;
- Summers, Charlotte;
- Dunmore, Benjamin J.;
- Farahi, Neda;
- Hayhoe, Richard P.;
- Print, Cristin G.;
- Cook, Simon J.;
- Chilvers, Edwin R.
Publication type:
Article
Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors.
Published in:
Intensive Care Medicine Experimental, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40635-021-00390-y
By:
- Lambden, Simon;
- Cowburn, Andrew S.;
- Macias, David;
- Garrud, Tessa A. C.;
- Krause, Bernardo J.;
- Giussani, Dino A.;
- Summers, Charlotte;
- Johnson, Randall S.
Publication type:
Article
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Published in:
Nature Communications, 2016, v. 7, n. 5, p. 11635, doi. 10.1038/ncomms11635
By:
- Semba, Hiroaki;
- Takeda, Norihiko;
- Isagawa, Takayuki;
- Sugiura, Yuki;
- Honda, Kurara;
- Wake, Masaki;
- Miyazawa, Hidenobu;
- Yamaguchi, Yoshifumi;
- Miura, Masayuki;
- Jenkins, Dana M. R.;
- Choi, Hyunsung;
- Kim, Jung-whan;
- Asagiri, Masataka;
- Cowburn, Andrew S.;
- Abe, Hajime;
- Soma, Katsura;
- Koyama, Katsuhiro;
- Katoh, Manami;
- Sayama, Keimon;
- Goda, Nobuhito
Publication type:
Article
Epidermal Deletion of HIF-2α Stimulates Wound Closure.
Published in:
Journal of Investigative Dermatology, 2014, v. 134, n. 3, p. 801, doi. 10.1038/jid.2013.395
By:
- Cowburn, Andrew S;
- Alexander, Laura E Crotty;
- Southwood, Mark;
- Nizet, Victor;
- Chilvers, Edwin R;
- Johnson, Randall S
Publication type:
Article
Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism.
Published in:
BMC Biology, 2015, v. 13, p. 1, doi. 10.1186/s12915-015-0221-6
By:
- Ashmore, Tom;
- Roberts, Lee D.;
- Morash, Andrea J.;
- Kotwica, Aleksandra O.;
- Finnerty, John;
- West, James A.;
- Murfitt, Steven A.;
- Fernandez, Bernadette O.;
- Branco, Cristina;
- Cowburn, Andrew S.;
- Clarke, Kieran;
- Johnson, Randall S.;
- Feelisch, Martin;
- Griffin, Julian L.;
- Murray, Andrew J.
Publication type:
Article
Human Cytomegalovirus Delays Neutropil Apoptosis and Stimulates the Release of a Prosurvival Secretome.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01185
By:
- Pocock1, Joanna M.;
- Storisteanu, Daniel M. L.;
- Reeves, Matthew B.;
- Juss, Jatinder K.;
- Wills, Mark R.;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.
Publication type:
Article
The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion.
Published in:
PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0160108
By:
- Fiddler, Christine A.;
- Parfrey, Helen;
- Cowburn, Andrew S.;
- Luo, Ding;
- Nash, Gerard B.;
- Murphy, Gillian;
- Chilvers, Edwin R.
Publication type:
Article
Neutrophil GM‐CSF receptor dynamics in acute lung injury.
Published in:
Journal of Leukocyte Biology, 2019, v. 105, n. 6, p. 1183, doi. 10.1002/JLB.3MA0918-347R
By:
- Alessandris, Silvia;
- Juss, Jatinder K.;
- Simmonds, Rosalind;
- Condliffe, Alison M.;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.;
- Ferguson, G. John;
- Dodd, Alison J.;
- Piper, Siân;
- Wyatt, Owen;
- Killick, Helen;
- Corkill, Dominic J.;
- Cohen, E. Suzanne;
- Sleeman, Matthew A.;
- Finch, Donna K.;
- Devaprasad, Abhinandan;
- Pandit, Aridaman;
- Radstake, Timothy R.D.J.
Publication type:
Article
Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart.
Published in:
Journal of Physiology, 2014, v. 592, n. 21, p. 4715, doi. 10.1113/jphysiol.2014.275263
By:
- Ashmore, Tom;
- Fernandez, Bernadette O.;
- Branco‐Price, Cristina;
- West, James A.;
- Cowburn, Andrew S.;
- Heather, Lisa C.;
- Griffin, Julian L.;
- Johnson, Randall S.;
- Feelisch, Martin;
- Murray, Andrew J.
Publication type:
Article
Changes in helper lymphocyte chemokine receptor expression and elevation of IP-10 during acute respiratory syncytial virus infection in infants.
Published in:
Pediatric Allergy & Immunology, 2011, v. 22, n. 2, p. 229, doi. 10.1111/j.1399-3038.2010.01032.x
By:
- Roe, Michael F. E.;
- Bloxham, David M.;
- Cowburn, Andrew S.;
- O'Donnell, Diarmuid R.
Publication type:
Article
The survival effect of TNF-α in human neutrophils is mediated via NF-κB-dependent IL-8 release.
Published in:
European Journal of Immunology, 2004, v. 34, n. 6, p. 1733, doi. 10.1002/eji.200425091
By:
- Cowburn, Andrew S.;
- Deighton, John;
- Walmsley, Sarah R.;
- Chilvers, Edwin R.
Publication type:
Article
The Influence of the Spleen on Neutrophil Apoptosis In Vivo.
Published in:
Journal of Cell Death, 2011, n. 4, p. 1, doi. 10.4137/JCD.S6444
By:
- White, Jessica F.;
- Cowburn, Andrew S.;
- Summers, Charlotte;
- Cadwallader, Karen A.;
- Mackenzie, Iain;
- Praseedom, Raaj K.;
- Chilvers, Edwin R.;
- Peters, A. Mike
Publication type:
Article

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