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Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin's Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug.
- Published in:
- Cardiovascular Toxicology, 2024, v. 24, n. 3, p. 266, doi. 10.1007/s12012-024-09829-6
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- Publication type:
- Article
Therapeutic Concentrations of Mitoxantrone Elicit Energetic Imbalance in H9c2 Cells as an Earlier Event.
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- Cardiovascular Toxicology, 2013, v. 13, n. 4, p. 413, doi. 10.1007/s12012-013-9224-0
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- Publication type:
- Article
The Metabolic Fingerprint of Doxorubicin-Induced Cardiotoxicity in Male CD-1 Mice Fades Away with Time While Autophagy Increases.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 11, p. 1613, doi. 10.3390/ph16111613
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- Publication type:
- Article
Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 6, p. 510, doi. 10.3390/ph14060510
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- Publication type:
- Article
Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A ‘Chemobrain’ In Vitro Study.
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- Pharmaceuticals (14248247), 2018, v. 11, n. 2, p. 41, doi. 10.3390/ph11020041
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- Publication type:
- Article
Inflammation as common link to progressive neurological diseases.
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- Archives of Toxicology, 2024, v. 98, n. 1, p. 95, doi. 10.1007/s00204-023-03628-8
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- Publication type:
- Article
The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice.
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- Archives of Toxicology, 2023, v. 97, n. 12, p. 3163, doi. 10.1007/s00204-023-03586-1
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- Publication type:
- Article
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice.
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- Archives of Toxicology, 2023, v. 97, n. 10, p. 2643, doi. 10.1007/s00204-023-03558-5
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- Publication type:
- Article
Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells.
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- Archives of Toxicology, 2023, v. 97, n. 1, p. 201, doi. 10.1007/s00204-022-03363-6
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- Publication type:
- Article
Chemobrain: mitoxantrone-induced oxidative stress, apoptotic and autophagic neuronal death in adult CD-1 mice.
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- Archives of Toxicology, 2022, v. 96, n. 6, p. 1767, doi. 10.1007/s00204-022-03261-x
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- Publication type:
- Article
The Role of Nrf2 and Inflammation on the Dissimilar Cardiotoxicity of Doxorubicin in Two-Time Points: a Cardio-Oncology In Vivo Study Through Time.
- Published in:
- Inflammation, 2024, v. 47, n. 1, p. 264, doi. 10.1007/s10753-023-01908-0
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- Publication type:
- Article
Cardiac Molecular Remodeling by Anticancer Drugs: Doxorubicin Affects More Metabolism While Mitoxantrone Impacts More Autophagy in Adult CD-1 Male Mice.
- Published in:
- Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 921, doi. 10.3390/biom13060921
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- Publication type:
- Article
Natural Sympathomimetic Drugs: From Pharmacology to Toxicology.
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- Biomolecules (2218-273X), 2022, v. 12, n. 12, p. 1793, doi. 10.3390/biom12121793
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- Publication type:
- Article
Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 11, p. 1725, doi. 10.3390/biom11111725
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- Publication type:
- Article
The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells.
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- Biomolecules (2218-273X), 2019, v. 9, n. 3, p. 98, doi. 10.3390/biom9030098
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- Publication type:
- Article
Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 1, p. 21, doi. 10.3390/biom9010021
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- Publication type:
- Article
"Ecstasy" toxicity to adolescent rats following an acute low binge dose.
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- BMC Pharmacology & Toxicology, 2016, v. 17, p. 1, doi. 10.1186/s40360-016-0070-0
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- Publication type:
- Article
Comprehensive review of cardiovascular toxicity of drugs and related agents.
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- Medicinal Research Reviews, 2018, v. 38, n. 4, p. 1332, doi. 10.1002/med.21476
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- Publication type:
- Article
Evaluation of GSH adducts of adrenaline in biological samples.
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- Biomedical Chromatography, 2007, v. 21, n. 7, p. 670, doi. 10.1002/bmc.796
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- Article
Pharmacology and Toxicology of Amphetamine-Type Stimulants.
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- 2023
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- Publication type:
- Editorial
Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity.
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- Journal of Applied Toxicology, 2016, v. 36, n. 10, p. 1321, doi. 10.1002/jat.3323
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- Publication type:
- Article
Inosine Strongly Enhances Proliferation of Human C32 Melanoma Cells through PLC- PKC- MEK1/2- ERK1/2 and PI3K Pathways.
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- Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 1, p. 25, doi. 10.1111/bcpt.12280
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- Publication type:
- Article
Cardiotoxicity of cyclophosphamide's metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes.
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- Archives of Toxicology, 2022, v. 96, n. 2, p. 653, doi. 10.1007/s00204-021-03204-y
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- Publication type:
- Article
Four decades of chemotherapy-induced cognitive dysfunction: comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events.
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- Archives of Toxicology, 2022, v. 96, n. 1, p. 11, doi. 10.1007/s00204-021-03171-4
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- Article
An updated review on synthetic cathinones.
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- Archives of Toxicology, 2021, v. 95, n. 9, p. 2895, doi. 10.1007/s00204-021-03083-3
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- Publication type:
- Article
In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV).
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- Archives of Toxicology, 2021, v. 95, n. 2, p. 509, doi. 10.1007/s00204-020-02949-2
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- Publication type:
- Article
Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations.
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- Archives of Toxicology, 2020, v. 94, n. 12, p. 4067, doi. 10.1007/s00204-020-02874-4
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- Publication type:
- Article
Adverse outcome pathways induced by 3,4-dimethylmethcathinone and 4-methylmethcathinone in differentiated human SH-SY5Y neuronal cells.
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- Archives of Toxicology, 2020, v. 94, n. 7, p. 2481, doi. 10.1007/s00204-020-02761-y
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- Publication type:
- Article
An effective antidotal combination of polymyxin B and methylprednisolone for α-amanitin intoxication.
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- Archives of Toxicology, 2019, v. 93, n. 5, p. 1449, doi. 10.1007/s00204-019-02426-5
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- Publication type:
- Article
Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes.
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- Archives of Toxicology, 2011, v. 85, n. 8, p. 929, doi. 10.1007/s00204-010-0630-9
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- Publication type:
- Article
Amphetamine and methylphenidate potential on the recovery from stroke and traumatic brain injury: a review.
- Published in:
- Reviews in the Neurosciences, 2024, v. 35, n. 7, p. 709, doi. 10.1515/revneuro-2024-0016
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- Publication type:
- Article
A Clinically Relevant Dosage of Mitoxantrone Disrupts the Glutathione and Lipid Metabolic Pathways of the CD-1 Mice Brain: A Metabolomics Study.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13126, doi. 10.3390/ijms241713126
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- Publication type:
- Article
Methylphenidate effects in the young brain: friend or foe?
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- International Journal of Developmental Neuroscience, 2017, v. 60, p. 34, doi. 10.1016/j.ijdevneu.2017.04.002
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- Publication type:
- Article
The neurotoxicity of amphetamines during the adolescent period.
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- International Journal of Developmental Neuroscience, 2015, v. 41, p. 44, doi. 10.1016/j.ijdevneu.2014.12.001
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- Publication type:
- Article