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1536. Population Pharmacokinetic Analysis of Baloxavir Morboxil, a Cap-Dependent Endonuclease Inhibitor, in Adult and Adolescent Healthy Subjects and Influenza Patients and Exposure-Response Relationships in the Patients at High-Risk of Influenza Complications
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- Open Forum Infectious Diseases, 2019, v. 6, p. S559, doi. 10.1093/ofid/ofz360.1400
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- Article
A Pharmacokinetics–Time to Alleviation of Symptoms Model to Support Extrapolation of Baloxavir Marboxil Clinical Efficacy in Different Ethnic Groups with Influenza A or B.
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- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 2, p. 372, doi. 10.1002/cpt.2648
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- Article
How Semiphysiological Population Pharmacokinetic Modeling Incorporating Active Hepatic Uptake Supports Phase II Dose Selection of RO7049389, A Novel Anti–Hepatitis B Virus Drug.
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- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1081, doi. 10.1002/cpt.2184
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Pharmacokinetic modelling of valproic acid from routine clinical data in Egyptian epileptic patients.
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- European Journal of Clinical Pharmacology, 2004, v. 59, n. 11, p. 783, doi. 10.1007/s00228-003-0699-7
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- Article
Population pharmacokinetics and exposure-response analyses of trastuzumab in patients with advanced gastric or gastroesophageal junction cancer.
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- Cancer Chemotherapy & Pharmacology, 2014, v. 73, n. 4, p. 737, doi. 10.1007/s00280-014-2400-5
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- Article
Simulation‐based evaluation of the Pharmpy Automatic Model Development tool for population pharmacokinetic modeling in early clinical drug development.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 10, p. 1707, doi. 10.1002/psp4.13213
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- Article
A Model-Based Approach to Predict Longitudinal HbA1c, Using Early Phase Glucose Data From Type 2 Diabetes Mellitus Patients After Anti-Diabetic Treatment.
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- Journal of Clinical Pharmacology, 2013, v. 53, n. 6, p. 589, doi. 10.1002/jcph.86
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- Article
Pharmacokinetics, safety, and simulated efficacy of an influenza treatment, baloxavir marboxil, in Chinese individuals.
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- CTS: Clinical & Translational Science, 2022, v. 15, n. 5, p. 1196, doi. 10.1111/cts.13237
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Population Pharmacokinetic and Exposure–dizziness Modeling for a Metabotropic Glutamate Receptor Subtype 5 Negative Allosteric Modulator in Major Depressive Disorder Patients.
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- CTS: Clinical & Translational Science, 2018, v. 11, n. 5, p. 523, doi. 10.1111/cts.12566
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- Article
What drives the dynamics of HBV RNA during treatment?
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- Journal of Viral Hepatitis, 2021, v. 28, n. 2, p. 383, doi. 10.1111/jvh.13425
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- Article