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Chemische Epigenetik: der Einfluss chemischer und chemo‐biologischer Techniken auf die Zielstruktur‐Validierung von Bromodomänen.
Published in:
Angewandte Chemie, 2019, v. 131, n. 50, p. 18096, doi. 10.1002/ange.201812164
By:
- Schiedel, Matthias;
- Moroglu, Mustafa;
- Ascough, David M. H.;
- Chamberlain, Anna E. R.;
- Kamps, Jos J. A. G.;
- Sekirnik, Angelina R.;
- Conway, Stuart J.
Publication type:
Article
Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3.
Published in:
Angewandte Chemie, 2016, v. 128, n. 29, p. 8493, doi. 10.1002/ange.201602908
By:
- Sekirnik (née Measures), Angelina R.;
- Hewings, David S.;
- Theodoulou, Natalie H.;
- Jursins, Lukass;
- Lewendon, Katie R.;
- Jennings, Laura E.;
- Rooney, Timothy P. C.;
- Heightman, Tom D.;
- Conway, Stuart J.
Publication type:
Article
Synthesis of Highly Water-Soluble Adamantyl Phosphoinositide Derivatives.
Published in:
Australian Journal of Chemistry, 2015, v. 68, n. 4, p. 543, doi. 10.1071/CH14543
By:
- Gregory, Mark;
- Meng-Xin Yin;
- McConville, Malcolm J.;
- Williams, Eleanor;
- Bullock, Alex N.;
- Conway, Stuart J.;
- Burgess, Antony W.;
- Catimel, Bruno;
- Holmes, Andrew B.
Publication type:
Article
Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3.
Published in:
Angewandte Chemie International Edition, 2016, v. 55, n. 29, p. 8353, doi. 10.1002/anie.201602908
By:
- Sekirnik, Angelina R.;
- Hewings, David S.;
- Theodoulou, Natalie H.;
- Jursins, Lukass;
- Lewendon, Katie R.;
- Jennings, Laura E.;
- Rooney, Timothy P. C.;
- Heightman, Tom D.;
- Conway, Stuart J.
Publication type:
Article
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction.
Published in:
Angewandte Chemie International Edition, 2014, v. 53, n. 24, p. 6126, doi. 10.1002/anie.201402750
By:
- Rooney, Timothy P. C.;
- Filippakopoulos, Panagis;
- Fedorov, Oleg;
- Picaud, Sarah;
- Cortopassi, Wilian A.;
- Hay, Duncan A.;
- Martin, Sarah;
- Tumber, Anthony;
- Rogers, Catherine M.;
- Philpott, Martin;
- Wang, Minghua;
- Thompson, Amber L.;
- Heightman, Tom D.;
- Pryde, David C.;
- Cook, Andrew;
- Paton, Robert S.;
- Müller, Susanne;
- Knapp, Stefan;
- Brennan, Paul E.;
- Conway, Stuart J.
Publication type:
Article
Regulation of InsP<sub>3</sub> receptor activity by neuronal Ca<sup>2+</sup>-binding proteins.
Published in:
EMBO Journal, 2004, v. 23, n. 2, p. 312, doi. 10.1038/sj.emboj.7600037
By:
- Kasri, Nael Nadif;
- Holmes, Anthony M.;
- Bultynck, Geert;
- Parys, Jan B.;
- Bootman, Martin D.;
- Rietdorf, Katja;
- Missiaen, Ludwig;
- McDonald, Fraser;
- De Smedt, Humbert;
- Conway, Stuart J.;
- Holmes, Andrew B.;
- Berridge, Michael J.;
- Roderick, H. Llewelyn
Publication type:
Article
Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 6, p. 390, doi. 10.3390/metabo11060390
By:
- Flynn, Noah R.;
- Ward, Michael D.;
- Schleiff, Mary A.;
- Laurin, Corentine M. C.;
- Farmer, Rohit;
- Conway, Stuart J.;
- Boysen, Gunnar;
- Swamidass, S. Joshua;
- Miller, Grover P.
Publication type:
Article
Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals.
Published in:
British Journal of Pharmacology, 2003, v. 139, n. 8, p. 1523, doi. 10.1038/sj.bjp.0705377
By:
- Miller, Jacqueline C.;
- Howson, Patrick A.;
- Conway, Stuart J.;
- Williams, Richard V.;
- Clark, Barry P.;
- Jane, David E.
Publication type:
Article
High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions.
Published in:
Nucleic Acids Research, 2018, v. 46, n. 14, p. e86, doi. 10.1093/nar/gky410
By:
- Phillips, Jack O;
- Butt, Louise E;
- Henderson, Charlotte A;
- Devonshire, Martin;
- Healy, Jess;
- Conway, Stuart J;
- Locker, Nicolas;
- Pickford, Andrew R;
- Vincent, Helen A;
- Callaghan, Anastasia J
Publication type:
Article
Zap‐Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat.
Published in:
ChemMedChem, 2021, v. 16, n. 24, p. 3691, doi. 10.1002/cmdc.202100403
By:
- Troelsen, Kathrin S.;
- Calder, Ewen D. D.;
- Skwarska, Anna;
- Sneddon, Deborah;
- Hammond, Ester M.;
- Conway, Stuart J.
Publication type:
Article
Selective Fragments for the CREBBP Bromodomain Identified from an Encoded Self‐assembly Chemical Library.
Published in:
ChemMedChem, 2020, v. 15, n. 18, p. 1752, doi. 10.1002/cmdc.202000528
By:
- Catalano, Marco;
- Moroglu, Mustafa;
- Balbi, Petra;
- Mazzieri, Federica;
- Clayton, James;
- Andrews, Katrina H.;
- Bigatti, Martina;
- Scheuermann, Jörg;
- Conway, Stuart J.;
- Neri, Dario
Publication type:
Article
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction.
Published in:
Angewandte Chemie, 2014, v. 126, n. 24, p. 6240, doi. 10.1002/ange.201402750
By:
- Rooney, Timothy P. C.;
- Filippakopoulos, Panagis;
- Fedorov, Oleg;
- Picaud, Sarah;
- Cortopassi, Wilian A.;
- Hay, Duncan A.;
- Martin, Sarah;
- Tumber, Anthony;
- Rogers, Catherine M.;
- Philpott, Martin;
- Wang, Minghua;
- Thompson, Amber L.;
- Heightman, Tom D.;
- Pryde, David C.;
- Cook, Andrew;
- Paton, Robert S.;
- Müller, Susanne;
- Knapp, Stefan;
- Brennan, Paul E.;
- Conway, Stuart J.
Publication type:
Article
Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.
Published in:
Journal of Cell Biology, 2004, v. 166, n. 2, p. 193, doi. 10.1083/jcb.200309146
By:
- Chen, Rui;
- Valencia, Ignacio;
- Zhong, Fei;
- McColl, Karen S.;
- Roderick, H. Llewelyn;
- Bootman, Martin D.;
- Berridge, Michael J.;
- Conway, Stuart J.;
- Holmes, Andrew B.;
- Mignery, Gregory A.;
- Velez, Patricio;
- Distelhorst, Clark W.
Publication type:
Article
Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10882-x
By:
- Geddes, Barney A.;
- Jorrin, Beatriz;
- Poole, Philip S.;
- Paramasivan, Ponraj;
- Oldroyd, Giles E. D.;
- Joffrin, Amelie;
- Thompson, Amber L.;
- Christensen, Kirsten;
- Conway, Stuart J.;
- Brett, Paul
Publication type:
Article
A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks.
Published in:
Advanced Science, 2020, v. 7, n. 22, p. 1, doi. 10.1002/advs.202001970
By:
- Bassi, Gabriele;
- Favalli, Nicholas;
- Vuk, Miriam;
- Catalano, Marco;
- Martinelli, Adriano;
- Trenner, Anika;
- Porro, Antonio;
- Yang, Su;
- Tham, Chuin Lean;
- Moroglu, Mustafa;
- Yue, Wyatt W.;
- Conway, Stuart J.;
- Vogt, Peter K.;
- Sartori, Alessandro A.;
- Scheuermann, Jörg;
- Neri, Dario
Publication type:
Article
Carsten Schmuck and Helma Wennemers (eds). Highlights in bioorganic chemistry: methods and applications. Wiley-VCH; 2004, 600 pp; ISBN 3-527-30656-0 (paperback).
Published in:
Applied Organometallic Chemistry, 2006, v. 20, n. 7, p. 476, doi. 10.1002/aoc.1093
By:
- Conway, Stuart J.
Publication type:
Article
Chemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target Validation.
Published in:
Angewandte Chemie International Edition, 2019, v. 58, n. 50, p. 17930, doi. 10.1002/anie.201812164
By:
- Schiedel, Matthias;
- Moroglu, Mustafa;
- Ascough, David M. H.;
- Chamberlain, Anna E. R.;
- Kamps, Jos J. A. G.;
- Sekirnik, Angelina R.;
- Conway, Stuart J.
Publication type:
Article
Bürgenstock 2012: Reflections on stereochemistry.
Published in:
Nature Chemistry, 2013, v. 5, n. 2, p. 86, doi. 10.1038/nchem.1552
By:
- Conway, Stuart J.
Publication type:
Article

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