Found: 2

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  • Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.

    Published in:
    Nature Biotechnology, 2014, v. 32, n. 2, p. 191, doi. 10.1038/nbt.2797
    By:
    • Lewis, Steven M;
    • Wu, Xiufeng;
    • Pustilnik, Anna;
    • Sereno, Arlene;
    • Huang, Flora;
    • Rick, Heather L;
    • Guntas, Gurkan;
    • Leaver-Fay, Andrew;
    • Smith, Eric M;
    • Ho, Carolyn;
    • Hansen-Estruch, Christophe;
    • Chamberlain, Aaron K;
    • Truhlar, Stephanie M;
    • Conner, Elaine M;
    • Atwell, Shane;
    • Kuhlman, Brian;
    • Demarest, Stephen J
    Publication type:
    Article

  • Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16231-7
    By:
    • Froning, Karen;
    • Maguire, Jack;
    • Sereno, Arlene;
    • Huang, Flora;
    • Chang, Shawn;
    • Weichert, Kenneth;
    • Frommelt, Anton J.;
    • Dong, Jessica;
    • Wu, Xiufeng;
    • Austin, Heather;
    • Conner, Elaine M.;
    • Fitchett, Jonathan R.;
    • Heng, Aik Roy;
    • Balasubramaniam, Deepa;
    • Hilgers, Mark T.;
    • Kuhlman, Brian;
    • Demarest, Stephen J.
    Publication type:
    Article