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Prekallikrein – an emerging therapeutic target for Klebsiella pneumoniae infection?<sup>†</sup>.
Published in:
Journal of Pathology, 2020, v. 250, n. 4, p. 359, doi. 10.1002/path.5382
By:
- Lam, Zena;
- Condliffe, Alison M
Publication type:
Article
The Impact of Hypoxia on Neutrophil Degranulation and Consequences for the Host.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1183, doi. 10.3390/ijms21041183
By:
- Lodge, Katharine M.;
- Cowburn, Andrew S.;
- Li, Wei;
- Condliffe, Alison M.
Publication type:
Article
The Impact of Hypoxia on the Host-Pathogen Interaction between Neutrophils and Staphylococcus aureus.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 22, p. 5561, doi. 10.3390/ijms20225561
By:
- Hajdamowicz, Natalia H;
- Hull, Rebecca C;
- Foster, Simon J;
- Condliffe, Alison M
Publication type:
Article
Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00338
By:
- Condliffe, Alison M.;
- Chandra, Anita
Publication type:
Article
Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045933
By:
- Juss, Jatinder K.;
- Hayhoe, Richard P.;
- Owen, Charles E.;
- Bruce, Ian;
- Walmsley, Sarah R.;
- Cowburn, Andrew S.;
- Kulkarni, Suhasini;
- Boyle, Keith B.;
- Stephens, Len;
- Hawkins, Phillip T.;
- Chilvers, Edwin R.;
- Condliffe, Alison M.;
- Benarafa, Charaf
Publication type:
Article
Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial--MIST-3.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 208, n. 12, p. 1305, doi. 10.1164/rccm.202305-0854OC
By:
- Bedawi, Eihab O.;
- Stavroulias, Dionisios;
- Hedley, Emma;
- Blyth, KevinG.;
- Kirk, Alan;
- De Fonseka, Duneesha;
- Edwards, John G.;
- Internullo, Eveline;
- Corcoran, John P.;
- Marchbank, Adrian;
- Panchal, Rakesh;
- Caruana, Edward;
- Kadwani, Owais;
- Okiror, Lawrence;
- Saba, Tarek;
- Purohit, Manoj;
- Mercer, Rachel M.;
- Taberham, Rhona;
- Kanellakis, Nikolaos;
- Condliffe, Alison M.
Publication type:
Article
Early Video Assisted Thoracoscopic Surgery (VATS) or Intrapleural Enzyme Therapy (IET) in Pleural Infection -- a feasibility randomized controlled trial (The third Multicenter Intrapleural Sepsis Trial - MIST-3).
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 208, n. 12, p. E1, doi. 10.1164/rccm.202305-0854oc
By:
- Bedawi, Eihab O.;
- Stavroulias, Dionisios;
- Hedley, Emma;
- Blyth, Kevin G.;
- Kirk, Alan;
- De Fonseka, Duneesha;
- Edwards, John G.;
- Internullo, Eveline;
- Corcoran, John P.;
- Marchbank, Adrian;
- Panchal, Rakesh;
- Caruana, Edward;
- Kadwani, Owais;
- Okiror, Lawrence;
- Saba, Tarek;
- Purohit, Manoj;
- Mercer, Rachel M.;
- Taberham, Rhona;
- Kanellakis, Nikolaos;
- Condliffe, Alison M.
Publication type:
Article
The Biological Role of Pleural Fluid PAI-1 and Sonographic Septations in Pleural Infection: Analysis of a Prospectively Collected Clinical Outcome Study.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 6, p. 731, doi. 10.1164/rccm.202206-1084OC
By:
- Bedawi, Eihab O.;
- Kanellakis, Nikolaos I.;
- Corcoran, John P.;
- Yu Zhao;
- Hassan, Maged;
- Asciak, Rachelle;
- Mercer, Rachel M.;
- Sundaralingam, Anand;
- Addala, Dinesh N.;
- Miller, Robert F.;
- Tao Dong;
- Condliffe, Alison M.;
- Rahman, Najib M.
Publication type:
Article
Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease.
Published in:
2022
By:
- Lodge, Katharine M.;
- Vassallo, Arlette;
- Bin Liu;
- Merete Long;
- Zhen Tong;
- Newby, Paul R.;
- Agha-Jaffar, Danya;
- Paschalaki, Koralia;
- Green, Clara E.;
- Belchamber, Kylie B. R.;
- Ridger, Victoria C.;
- Stockley, Robert A.;
- Sapey, Elizabeth;
- Summers, Charlotte;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.;
- Wei Li;
- Condliffe, Alison M.;
- Liu, Bin;
- Long, Merete
Publication type:
journal article
Circulating BMP9 Protects the Pulmonary Endothelium during Inflammation-induced Lung Injury in Mice.
Published in:
2021
By:
- Wei Li;
- Lu Long;
- Xudong Yang;
- Zhen Tong;
- Southwood, Mark;
- King, Ross;
- Caruso, Paola;
- Upton, Paul D.;
- Peiran Yang;
- Bocobo, Geoffrey A.;
- Nikolic, Ivana;
- Higuera, Angelica;
- Salmon, Richard M.;
- He Jiang;
- Lodge, Katharine M.;
- Hoenderdos, Kim;
- Baron, Rebecca M.;
- Yu, Paul B.;
- Condliffe, Alison M.;
- Summers, Charlotte
Publication type:
journal article
Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells.
Published in:
Respiratory Research, 2000, v. 1, p. 24, doi. 10.1186/rr8
By:
- Condliffe, Alison M.;
- Cadwallader, Karen A.;
- Walker, Trevor R.;
- Rintoul, Robert C.;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.
Publication type:
Article
Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction.
Published in:
PLoS Pathogens, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.ppat.1009468
By:
- Sutton, Joshua A. F.;
- Carnell, Oliver T.;
- Lafage, Lucia;
- Gray, Joe;
- Biboy, Jacob;
- Gibson, Josie F.;
- Pollitt, Eric J. G.;
- Tazoll, Simone C.;
- Turnbull, William;
- Hajdamowicz, Natalia H.;
- Salamaga, Bartłomiej;
- Pidwill, Grace R.;
- Condliffe, Alison M.;
- Renshaw, Stephen A.;
- Vollmer, Waldemar;
- Foster, Simon J.
Publication type:
Article
Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01721
By:
- Hughes, Bethany M.;
- Burton, Charlotte S.;
- Reese, Abigail;
- Jabeen, Maisha F.;
- Wright, Carl;
- Willis, Jessica;
- Khoshaein, Nika;
- Marsh, Elizabeth K.;
- Peachell, Peter;
- Sun, Shao C.;
- Dockrell, David H.;
- Marriott, Helen M.;
- Sabroe, Ian;
- Condliffe, Alison M.;
- Prince, Lynne R.
Publication type:
Article
Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils.
Published in:
Nature Cell Biology, 2006, v. 8, n. 11, p. 1303, doi. 10.1038/ncb1494
By:
- Suire, Sabine;
- Condliffe, Alison M.;
- Ferguson, G. John;
- Ellson, Chris D.;
- Guillou, Hervé;
- Davidson, Keith;
- Welch, Heidi;
- Coadwell, John;
- Turner, Martin;
- Chilvers, Edwin R.;
- Hawkins, Phillip T.;
- Stephens, Len
Publication type:
Article
NBEAL2 is required for neutrophil and NK cell function and pathogen defense.
Published in:
2017
By:
- Sowerby, John M.;
- Thomas, David C.;
- Clare, Simon;
- Espéli, Marion;
- Guerrero, Jose A.;
- Hoenderdos, Kim;
- Harcourt, Katherine;
- Marsden, Morgan;
- Abdul-Karim, Juneid;
- Clement, Mathew;
- Antrobus, Robin;
- Umrania, Yagnesh;
- Barton, Philippa R.;
- Flint, Shaun M.;
- Juss, Jatinder K.;
- Condliffe, Alison M.;
- Lyons, Paul A.;
- Humphreys, Ian R.;
- Chilvers, Edwin R.;
- Ouwehand, Willem H.
Publication type:
journal article
Managing Granulomatous–Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders: e-GLILDnet International Clinicians Survey.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.606333
By:
- van de Ven, Annick A. J. M.;
- Alfaro, Tiago M.;
- Robinson, Alexandra;
- Baumann, Ulrich;
- Bergeron, Anne;
- Burns, Siobhan O.;
- Condliffe, Alison M.;
- Fevang, Børre;
- Gennery, Andrew R.;
- Haerynck, Filomeen;
- Jacob, Joseph;
- Jolles, Stephen;
- Malphettes, Marion;
- Meignin, Véronique;
- Milota, Tomas;
- van Montfrans, Joris;
- Prasse, Antje;
- Quinti, Isabella;
- Renzoni, Elisabetta;
- Stolz, Daiana
Publication type:
Article
Use of technetium-99m-labeled eosinophils to detect active eosinophilic inflammation in humans.
Published in:
2013
By:
- Farahi, Neda;
- Loutsios, Chrystalla;
- Peters, Adrien M;
- Condliffe, Alison M;
- Chilvers, Edwin R
Publication type:
Case Study
Use of Technetium-99m-labeled Eosinophils to Detect Active Eosinophilic Inflammation in Humans.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 188, n. 7, p. 880, doi. 10.1164/rccm.201303-0535le
By:
- FARAHI, NEDA;
- LOUTSIOS, CHRYSTALLA;
- PETERS, ADRIEN M.;
- CONDLIFFE, ALISON M.;
- CHILVERS, EDWIN R.
Publication type:
Article
Priming and de‐priming of neutrophil responses in vitro and in vivo.
Published in:
European Journal of Clinical Investigation, 2018, v. 48, p. N.PAG, doi. 10.1111/eci.12967
By:
- Vogt, Katja L.;
- Summers, Charlotte;
- Chilvers, Edwin R.;
- Condliffe, Alison M.
Publication type:
Article
Neutrophil GM‐CSF receptor dynamics in acute lung injury.
Published in:
Journal of Leukocyte Biology, 2019, v. 105, n. 6, p. 1183, doi. 10.1002/JLB.3MA0918-347R
By:
- Alessandris, Silvia;
- Juss, Jatinder K.;
- Simmonds, Rosalind;
- Condliffe, Alison M.;
- Cowburn, Andrew S.;
- Chilvers, Edwin R.;
- Ferguson, G. John;
- Dodd, Alison J.;
- Piper, Siân;
- Wyatt, Owen;
- Killick, Helen;
- Corkill, Dominic J.;
- Cohen, E. Suzanne;
- Sleeman, Matthew A.;
- Finch, Donna K.;
- Devaprasad, Abhinandan;
- Pandit, Aridaman;
- Radstake, Timothy R.D.J.
Publication type:
Article
Coexistence of Bronchiectasis and Rheumatoid Arthritis: Revisited.
Published in:
Respiratory Care, 2013, v. 58, n. 4, p. 694, doi. 10.4187/respcare.01857
By:
- Wilczynska, Maria M;
- Condliffe, Alison M;
- Mckeon, Damian J
Publication type:
Article
Phosphoinositide 3-kinase δ (PI3Kδ) in respiratory disease.
Published in:
Biochemical Society Transactions, 2018, v. 46, n. 2, p. 361, doi. 10.1042/BST20170467
By:
- Stokes, Clare A.;
- Condliffe, Alison M.
Publication type:
Article
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05674-8
By:
- Stark, Anne-Katrien;
- Chandra, Anita;
- Chakraborty, Krishnendu;
- Alam, Rafeah;
- Carbonaro, Valentina;
- Clark, Jonathan;
- Sriskantharajah, Srividya;
- Bradley, Glyn;
- Richter, Alex G.;
- Banham-Hall, Edward;
- Clatworthy, Menna R.;
- Nejentsev, Sergey;
- Hamblin, J. Nicole;
- Hessel, Edith M.;
- Condliffe, Alison M.;
- Okkenhaug, Klaus
Publication type:
Article
A serum calprotectin lateral flow test as an inflammatory and prognostic marker in acute lung infection: a prospective observational study.
Published in:
ERJ Open Research, 2024, v. 10, n. 3, p. 1, doi. 10.1183/23120541.00059-2024
By:
- Gilmour, Amy;
- Hughes, Chloe;
- Yan Hui Giam;
- Hull, Rebecca C.;
- Pembridge, Thomas;
- Abo-Leyah, Hani;
- Roger Thompson, A. A.;
- Condliffe, Alison M.;
- Shoemark, Amelia;
- Chalmers, James D.;
- Long, Merete B.
Publication type:
Article
A Fun-Guide to Innate Immune Responses to Fungal Infections.
Published in:
Journal of Fungi, 2022, v. 8, n. 8, p. 805, doi. 10.3390/jof8080805
By:
- Burgess, Thomas B.;
- Condliffe, Alison M.;
- Elks, Philip M.
Publication type:
Article
Seasonal Azithromycin Use in Paediatric Protracted Bacterial Bronchitis Does Not Promote Antimicrobial Resistance but Does Modulate the Nasopharyngeal Microbiome.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 22, p. 16053, doi. 10.3390/ijms242216053
By:
- Hardman, Simon J.;
- Shackley, Fiona M.;
- Ugonna, Kelechi;
- Darton, Thomas C.;
- Rigby, Alan S.;
- Bogaert, Debby;
- Binkowska, Justyna M.;
- Condliffe, Alison M.
Publication type:
Article
Clinical, Immunological, and Genetic Features in Patients with Activated PI3Kδ Syndrome (APDS): a Systematic Review.
Published in:
Clinical Reviews in Allergy & Immunology, 2020, v. 59, n. 3, p. 323, doi. 10.1007/s12016-019-08738-9
By:
- Jamee, Mahnaz;
- Moniri, Shakiba;
- Zaki-Dizaji, Majid;
- Olbrich, Peter;
- Yazdani, Reza;
- Jadidi-Niaragh, Farhad;
- Aghamahdi, Fatemeh;
- Abolhassani, Hassan;
- Condliffe, Alison M.;
- Aghamohammadi, Asghar;
- Azizi, Gholamreza
Publication type:
Article
Moving in mysterious ways.
Published in:
Nature, 2000, v. 404, n. 6774, p. 135, doi. 10.1038/35004693
By:
- Condliffe, Alison M.;
- Hawkins, Phillip T.
Publication type:
Article

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