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α-Synuclein Seed Amplification in CSF and Brain from Patients with Different Brain Distributions of Pathological α-Synuclein in the Context of Co-Pathology and Non-LBD Diagnoses.
Published in:
2022
By:
- Arnold, Moriah R.;
- Coughlin, David G.;
- Brumbach, Barbara H.;
- Smirnov, Denis S.;
- Concha‐Marambio, Luis;
- Farris, Carly M.;
- Ma, Yihua;
- Kim, Yongya;
- Wilson, Edward N.;
- Kaye, Jeffrey A.;
- Hiniker, Annie;
- Woltjer, Randy L.;
- Galasko, Doug R.;
- Quinn, Joseph F.;
- Concha-Marambio, Luis
Publication type:
journal article
Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Published in:
2021
By:
- Russo, Marco J.;
- Orru, Christina D.;
- Concha-Marambio, Luis;
- Giaisi, Simone;
- Groveman, Bradley R.;
- Farris, Carly M.;
- Holguin, Bret;
- Hughson, Andrew G.;
- LaFontant, David-Erick;
- Caspell-Garcia, Chelsea;
- Cofey, Christopher S.;
- Mollon, Jennifer;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Heym, Roland G.;
- Soto, Claudio;
- Caughey, Byron;
- Kang, Un Jung
Publication type:
Correction Notice
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8
By:
- Russo, Marco J.;
- Orru, Christina D.;
- Concha-Marambio, Luis;
- Giaisi, Simone;
- Groveman, Bradley R.;
- Farris, Carly M.;
- Holguin, Bret;
- Hughson, Andrew G.;
- LaFontant, David-Erick;
- Caspell-Garcia, Chelsea;
- Coffey, Christopher S.;
- Mollon, Jennifer;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Heym, Roland G.;
- Soto, Claudio;
- Caughey, Byron;
- Kang, Un Jung
Publication type:
Article
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8
By:
- Russo, Marco J.;
- Orru, Christina D.;
- Concha-Marambio, Luis;
- Giaisi, Simone;
- Groveman, Bradley R.;
- Farris, Carly M.;
- Holguin, Bret;
- Hughson, Andrew G.;
- LaFontant, David-Erick;
- Caspell-Garcia, Chelsea;
- Coffey, Christopher S.;
- Mollon, Jennifer;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Heym, Roland G.;
- Soto, Claudio;
- Caughey, Byron;
- Kang, Un Jung
Publication type:
Article
Preclinical Detection of Prions in Blood of Nonhuman Primates Infected with Variant Creutzfeldt-Jakob Disease.
Published in:
2020
By:
- Concha-Marambio, Luis;
- Chacon, Marcelo A.;
- Soto, Claudio
Publication type:
journal article
Recent US Case of Variant Creutzfeldt-Jakob Disease-Global Implications.
Published in:
2015
By:
- Maheshwari, Atul;
- Fischer, Michael;
- Gambetti, Pierluigi;
- Parker, Alicia;
- Ram, Aarthi;
- Soto, Claudio;
- Concha-Marambio, Luis;
- Cohen, Yvonne;
- Belay, Ermias D;
- Maddox, Ryan A;
- Mead, Simon;
- Goodman, Clay;
- Kass, Joseph S;
- Schonberger, Lawrence B;
- Hussein, Haitham M
Publication type:
journal article
Recent US Case of Variant Creutzfeldt-Jakob Disease--Global Implications.
Published in:
2015
By:
- Maheshwari, Atul;
- Fischer, Michael;
- Gambetti, Pierluigi;
- Parker, Alicia;
- Ram, Aarthi;
- Soto, Claudio;
- Concha-Marambio, Luis;
- Cohen, Yvonne;
- Belay, Ermias D.;
- Maddox, Ryan A.;
- Mead, Simon;
- Goodman, Clay;
- Kass, Joseph S.;
- Schonberger, Lawrence B.;
- Hussein, Haitham M.
Publication type:
Case Study
Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 5, p. 3334, doi. 10.1002/alz.13799
By:
- Samudra, Niyatee;
- Fischer, D. Luke;
- Lenio, Steven;
- Lario Lago, Argentina;
- Ljubenkov, Peter A.;
- Rojas, Julio C.;
- Seeley, William W.;
- Spina, Salvatore;
- Staffaroni, Adam M.;
- Tablante, Jonathan;
- Wekselman, Fattin;
- Lamoureux, Jennifer;
- Concha‐Marambio, Luis;
- Grinberg, Lea T.;
- Boxer, Adam L.;
- VandeVrede, Lawren
Publication type:
Article
Investigating alpha‐synuclein co‐pathology in Alzheimer's disease by means of cerebrospinal fluid alpha‐synuclein seed amplification assay.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2444, doi. 10.1002/alz.13658
By:
- Bellomo, Giovanni;
- Toja, Andrea;
- Paolini Paoletti, Federico;
- Ma, Yihua;
- Farris, Carly M.;
- Gaetani, Lorenzo;
- Salvadori, Nicola;
- Chiasserini, Davide;
- Wojdaƚa, Anna Lidia;
- Concha‐Marambio, Luis;
- Parnetti, Lucilla
Publication type:
Article
The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.
Published in:
Scientific Reports, 2017, p. 44723, doi. 10.1038/srep44723
By:
- Park, Kyung-Won;
- Eun Kim, Gyoung;
- Morales, Rodrigo;
- Moda, Fabio;
- Moreno-Gonzalez, Ines;
- Concha-Marambio, Luis;
- Lee, Amy S.;
- Hetz, Claudio;
- Soto, Claudio
Publication type:
Article
Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo.
Published in:
Scientific Reports, 2016, p. 32338, doi. 10.1038/srep32338
By:
- Urayama, Akihiko;
- Concha-Marambio, Luis;
- Khan, Uffaf;
- Bravo-Alegria, Javiera;
- Kharat, Vineetkumar;
- Soto, Claudio
Publication type:
Article
Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease.
Published in:
Science Translational Medicine, 2016, v. 8, n. 370, p. 1, doi. 10.1126/scitranslmed.aaf6188
By:
- Concha-Marambio, Luis;
- Pritzkow, Sandra;
- Moda, Fabio;
- Tagliavini, Fabrizio;
- Ironside, James W.;
- Schulz, Paul E.;
- Soto, Claudio
Publication type:
Article
Seed amplification assay results illustrate discrepancy in Parkinson's disease clinical diagnostic accuracy and error rates.
Published in:
Journal of Neurology, 2023, v. 270, n. 12, p. 5813, doi. 10.1007/s00415-023-11810-2
By:
- Middleton, John Stephen;
- Hovren, Hanna Lynn;
- Kha, Nelson;
- Medina, Manuel Joseph;
- MacLeod, Karen Ruth;
- Concha-Marambio, Luis;
- Jensen, Kendal Jay
Publication type:
Article
Accurate Detection of α‐Synuclein Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort.
Published in:
Movement Disorders, 2023, v. 38, n. 4, p. 567, doi. 10.1002/mds.29329
By:
- Concha‐Marambio, Luis;
- Weber, Sandrina;
- Farris, Carly M.;
- Dakna, Mohammed;
- Lang, Elisabeth;
- Wicke, Tamara;
- Ma, Yihua;
- Starke, Maritta;
- Ebentheuer, Jens;
- Sixel‐Döring, Friederike;
- Muntean, Maria‐Lucia;
- Schade, Sebastian;
- Trenkwalder, Claudia;
- Soto, Claudio;
- Mollenhauer, Brit
Publication type:
Article
Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression.
Published in:
Movement Disorders, 2021, v. 36, n. 10, p. 2444, doi. 10.1002/mds.28715
By:
- Concha‐Marambio, Luis;
- Farris, Carly M.;
- Holguin, Bret;
- Ma, Yihua;
- Seibyl, John;
- Russo, Marco J.;
- Kang, Un J.;
- Hutten, Samantha J.;
- Merchant, Kalpana;
- Shahnawaz, Mohammad;
- Soto, Claudio
Publication type:
Article
Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid.
Published in:
Nature Protocols, 2023, v. 18, n. 4, p. 1179, doi. 10.1038/s41596-022-00787-3
By:
- Concha-Marambio, Luis;
- Pritzkow, Sandra;
- Shahnawaz, Mohammad;
- Farris, Carly M.;
- Soto, Claudio
Publication type:
Article
Thermal adaptation of mesophilic and thermophilic FtsZ assembly by modulation of the critical concentration.
Published in:
PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0185707
By:
- Concha-Marambio, Luis;
- Maldonado, Paula;
- Lagos, Rosalba;
- Monasterio, Octavio;
- Montecinos-Franjola, Felipe
Publication type:
Article
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays.
Published in:
Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00613-8
By:
- Bellomo, Giovanni;
- Paciotti, Silvia;
- Concha-Marambio, Luis;
- Rizzo, Domenico;
- Wojdaƚa, Anna Lidia;
- Chiasserini, Davide;
- Gatticchi, Leonardo;
- Cerofolini, Linda;
- Giuntini, Stefano;
- De Luca, Chiara Maria Giulia;
- Ma, Yihua;
- Farris, Carly M.;
- Pieraccini, Giuseppe;
- Bologna, Sara;
- Filidei, Marta;
- Ravera, Enrico;
- Lelli, Moreno;
- Moda, Fabio;
- Fragai, Marco;
- Parnetti, Lucilla
Publication type:
Article

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