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Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.988748
By:
- Ng, Jerome P. L.;
- Yu Han;
- Li Jun Yang;
- Birkholtz, Lyn-Marie;
- Coertzen, Dina;
- Ho Ning Wong;
- Haynes, Richard K.;
- Coghi, Paolo;
- Kam Wai Wong, Vincent
Publication type:
Article
Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites.
Published in:
Communications Chemistry, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0062-7
By:
- Beteck, Richard M.;
- Seldon, Ronnett;
- Coertzen, Dina;
- van der Watt, Mariëtte E.;
- Reader, Janette;
- Mackenzie, Jared S.;
- Lamprecht, Dirk A.;
- Abraham, Matthew;
- Eribez, Korina;
- Müller, Joachim;
- Rui, Feng;
- Zhu, Guang;
- de Grano, Ruel Valerio;
- Williams, Ian D.;
- Smit, Frans J.;
- Steyn, Adrie J. C.;
- Winzeler, Elizabeth A.;
- Hemphill, Andrew;
- Birkholtz, Lyn-Marie;
- Warner, Digby F.
Publication type:
Article
Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli.
Published in:
PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0152626
By:
- Makhoba, Xolani Henry;
- Burger, Adélle;
- Coertzen, Dina;
- Zininga, Tawanda;
- Birkholtz, Lyn-Marie;
- Shonhai, Addmore
Publication type:
Article
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
Published in:
Science Translational Medicine, 2022, v. 14, n. 667, p. 1, doi. 10.1126/scitranslmed.abo7219
By:
- Arendse, Lauren B.;
- Murithi, James M.;
- Qahash, Tarrick;
- Pasaje, Charisse Flerida A.;
- Godoy, Luiz C.;
- Dey, Sumanta;
- Gibhard, Liezl;
- Ghidelli-Disse, Sonja;
- Drewes, Gerard;
- Bantscheff, Marcus;
- Lafuente-Monasterio, Maria J.;
- Fienberg, Stephen;
- Wambua, Lynn;
- Gachuhi, Samuel;
- Coertzen, Dina;
- van der Watt, Mariëtte;
- Reader, Janette;
- Aswat, Ayesha S.;
- Erlank, Erica;
- Venter, Nelius
Publication type:
Article
Preliminary Evaluation of Artemisinin–Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.
Published in:
ChemMedChem, 2018, v. 13, n. 1, p. 67, doi. 10.1002/cmdc.201700579
By:
- Morake, Mokhitli;
- Coertzen, Dina;
- Ngwane, Andile;
- Wentzel, Johannes F.;
- Wong, Ho Ning;
- Smit, Frans J.;
- Birkholtz, Lyn‐Marie;
- Pietersen, Ray‐Dean;
- Baker, Bienyameen;
- Wiid, Ian;
- N'Da, David D.;
- Haynes, Richard K.
Publication type:
Article
Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.
Published in:
ChemMedChem, 2017, v. 12, n. 24, p. 2086, doi. 10.1002/cmdc.201700599
By:
- Harmse, Rozanne;
- Coertzen, Dina;
- Wong, Ho Ning;
- Smit, Frans J.;
- van der Watt, Mariette E.;
- Reader, Janette;
- Nondaba, Sindiswe H.;
- Birkholtz, Lyn‐Marie;
- Haynes, Richard K.;
- N'Da, David D.
Publication type:
Article

Found: 6

Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue.

Accessible and distinct decoquinate derivatives active against Mycobacterium tuberculosis and apicomplexan parasites.

Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli.

The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.

Preliminary Evaluation of Artemisinin–Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.

Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.