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The Adverse Outcome Pathway Framework Applied to Neurological Symptoms of COVID-19.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 21, p. 3411, doi. 10.3390/cells11213411
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Mechanistic Understanding of the Olfactory Neuroepithelium Involvement Leading to Short-Term Anosmia in COVID-19 Using the Adverse Outcome Pathway Framework.
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- Cells (2073-4409), 2022, v. 11, n. 19, p. 3027, doi. 10.3390/cells11193027
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- Article
Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide.
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- Journal of Neurochemistry, 2006, v. 99, n. 2, p. 596, doi. 10.1111/j.1471-4159.2006.04085.x
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- Article
Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation.
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- Journal of Neurochemistry, 2005, v. 95, n. 4, p. 1132, doi. 10.1111/j.1471-4159.2005.03422.x
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- Article
A worldwide survey on the use of animal‐derived materials and reagents in scientific experimentation.
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- Engineering in Life Sciences, 2022, v. 22, n. 9, p. 564, doi. 10.1002/elsc.202100167
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Cytochrome P450 Induction and Xeno‐Sensing Receptors Pregnane X Receptor, Constitutive Androstane Receptor, Aryl Hydrocarbon Receptor and Peroxisome Proliferator‐Activated Receptor α at the Crossroads of Toxicokinetics and Toxicodynamics.
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- Basic & Clinical Pharmacology & Toxicology, 2018, v. 123, p. 42, doi. 10.1111/bcpt.13004
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Building an Adverse Outcome Pathway network for COVID-19.
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- Frontiers in Systems Biology, 2024, p. 1, doi. 10.3389/fsysb.2024.1384481
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- Article
Covid-19 Through Adverse Outcome Pathways: Building Networks To Better Understand the Disease – 3<sup>rd</sup> CIAO AOP Design Workshop.
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- Altex, 2022, v. 39, n. 2, p. 322, doi. 10.14573/altex.2112161
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Guidance Document on Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0).
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- Altex, 2022, v. 39, n. 1, p. 30, doi. 10.14573/altex.2111011
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- Article
New Approach Methodologies (NAMs) for Human-Relevant Biokinetics Predictions: Meeting the Paradigm Shift in Toxicology Towards an Animal-Free Chemical Risk Assessment.
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- Altex, 2020, v. 37, n. 4, p. 607, doi. 10.14573/altex.2003242
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Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0) - Draft for Stakeholder Discussion and Call for Action.
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- Altex, 2020, v. 37, n. 3, p. 490, doi. 10.14573/altex.2007091
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Advanced Good Cell Culture Practice for Human Primary, Stem Cell-Derived and Organoid Models as well as Microphysiological Systems.
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- Altex, 2018, v. 35, n. 3, p. 353, doi. 10.14573/altex.1710081
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- Article
Good Cell Culture Practice for Stem Cells and Stem-Cell-Derived Models.
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- Altex, 2017, v. 34, n. 1, p. 95, doi. 10.14573/altex.1607121
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Finding Opportunities in the Area of Alternative Methods to Animal Testing for Romania and Inauguration of the Romanian Center for Alternative Test Methods (ROCAM).
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- Altex, 2015, v. 32, n. 4, p. 392, doi. 10.14573/altex.1509281
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Advancing the Science of Developmental Neurotoxicity (DNT): Testing for Better Safety Evaluation.
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- Altex, 2012, v. 29, n. 2, p. 202, doi. 10.14573/altex.2012.2.202
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A Human Stem Cell-Based Model for Identifying Adverse Effects of Organic and Inorganic Chemicals on the Developing Nervous System.
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- Stem Cells, 2009, v. 27, n. 10, p. 2591, doi. 10.1002/stem.179
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Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.
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- Archives of Toxicology, 2012, v. 86, n. 3, p. 393, doi. 10.1007/s00204-011-0768-0
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- Article
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.
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- Archives of Toxicology, 2011, v. 85, n. 5, p. 367, doi. 10.1007/s00204-011-0693-2
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Molecular effects of fermented papaya preparation on oxidative damage, MAP Kinase activation and modulation of the benzo[a]pyrene mediated genotoxicity.
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- Biofactors, 2006, v. 26, n. 2, p. 147, doi. 10.1002/biof.5520260205
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A pragmatic framework for the application of new approach methodologies in one health toxicological risk assessment.
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- Toxicological Sciences, 2023, v. 192, n. 2, p. 155, doi. 10.1093/toxsci/kfad012
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- Article
Three-Dimensional HepaRG Model As An Attractive Tool for Toxicity Testing.
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- Toxicological Sciences, 2012, v. 130, n. 1, p. 106, doi. 10.1093/toxsci/kfs232
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- Article
mRNA Expression is a Relevant Tool to Identify Developmental Neurotoxicants Using an In Vitro Approach.
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- Toxicological Sciences, 2010, v. 113, n. 1, p. 95, doi. 10.1093/toxsci/kfp175
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- Article
Mechanisms Leading to Gut Dysbiosis in COVID-19: Current Evidence and Uncertainties Based on Adverse Outcome Pathways.
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- Journal of Clinical Medicine, 2022, v. 11, n. 18, p. N.PAG, doi. 10.3390/jcm11185400
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Factors Modulating COVID-19: A Mechanistic Understanding Based on the Adverse Outcome Pathway Framework.
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- Journal of Clinical Medicine, 2022, v. 11, n. 15, p. 4464, doi. 10.3390/jcm11154464
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- Article
Comparative Effects of Di-(2-ethylhexyl)phthalate and Di-(2-ethylhexyl)terephthalate Metabolites on Thyroid Receptors: In Vitro and In Silico Studies.
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- Metabolites (2218-1989), 2021, v. 11, n. 2, p. 94, doi. 10.3390/metabo11020094
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Advances in Animal Models and Cutting-Edge Research in Alternatives: Proceedings of the Third International Conference on 3Rs Research and Progress, Vishakhapatnam, 2022.
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- Alternatives to Laboratory Animals, 2023, v. 51, n. 4, p. 263, doi. 10.1177/02611929231180428
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Report of the EPAA-ECVAM Workshop on the Validation of Integrated Testing Strategies (ITS).
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- Alternatives to Laboratory Animals, 2012, v. 40, n. 3, p. 175, doi. 10.1177/026119291204000310
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Toward Preclinical Predictive Drug Testing for Metabolism and Hepatotoxicity by Using In Vitro Models Derived from Human Embryonic Stem Cells and Human Cell Lines--A Report on the Vitrocellomics EU-project.
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- Alternatives to Laboratory Animals, 2011, v. 39, n. 2, p. 147, doi. 10.1177/026119291103900210
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- Article
Workgroup Report: Incorporating In Vitro Alternative Methods for Developmental Neurotoxicity into International Hazard and Risk Assessment Strategies.
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- Environmental Health Perspectives, 2007, v. 115, n. 6, p. 989, doi. 10.1289/ehp.9427
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Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM-ICCVAM/NICEATM Considerations for Regulatory Use.
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- Environmental Health Perspectives, 2006, v. 114, n. 3, p. 420, doi. 10.1289/ehp.8247
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- Article