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The drug interaction potential of daprodustat when coadministered with pioglitazone, rosuvastatin, or trimethoprim in healthy subjects.
Published in:
Pharmacology Research & Perspectives, 2018, v. 6, n. 2, p. 1, doi. 10.1002/prp2.327
By:
- Caltabiano, Stephen;
- Mahar, Kelly M.;
- Lister, Karyn;
- Tenero, David;
- Ravindranath, Ramiya;
- Cizman, Borut;
- Cobitz, Alexander R.
Publication type:
Article
Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients: A Randomized Clinical Trial.
Published in:
2022
By:
- Singh, Ajay K.;
- Cizman, Borut;
- Carroll, Kevin;
- McMurray, John J. V.;
- Perkovic, Vlado;
- Jha, Vivekanand;
- Johansen, Kirsten L.;
- Lopes, Renato D.;
- Macdougall, Iain C.;
- Obrador, Gregorio T.;
- Waikar, Sushrut S.;
- Wanner, Christoph;
- Wheeler, David C.;
- Wiecek, Andrzej;
- Stankus, Nicole;
- Strutz, Frank;
- Blackorby, Allison;
- Cobitz, Alexander R.;
- Meadowcroft, Amy M.;
- Paul, Gitanjali
Publication type:
journal article
Pharmacokinetics of Daprodustat and Metabolites in Individuals with Normal and Impaired Hepatic Function.
Published in:
Clinical Pharmacology in Drug Development, 2022, v. 11, n. 5, p. 562, doi. 10.1002/cpdd.1090
By:
- Mahar, Kelly M.;
- Shaddinger, Bonnie C.;
- Ramanjineyulu, Bandi;
- Andrews, Susan;
- Caltabiano, Stephen;
- Lindsay, Alistair C.;
- Cobitz, Alexander R.
Publication type:
Article
Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability Determination.
Published in:
Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1419, doi. 10.1002/cpdd.1029
By:
- Mahar, Kelly M.;
- Caltabiano, Stephen;
- Andrews, Susan;
- Ramanjineyulu, Bandi;
- Chen, Liangfu;
- Young, Graeme;
- Pereira, Adrian;
- Lindsay, Alistair C.;
- van den Berg, Frans;
- Cobitz, Alexander R.
Publication type:
Article
A Randomized, Placebo‐ and Positive‐Controlled, Single‐Dose, Crossover Thorough QT/QTc Study Assessing the Effect of Daprodustat on Cardiac Repolarization in Healthy Subjects.
Published in:
Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 627, doi. 10.1002/cpdd.342
By:
- Caltabiano, Stephen;
- Collins, Jon;
- Serbest, Gul;
- Morgan, Lisa;
- Smith, Deborah A.;
- Ravindranath, Ramiya;
- Cobitz, Alexander R.
Publication type:
Article
Analysis of on-treatment cancer safety events with daprodustat versus conventional erythropoiesis-stimulating agents—post hoc analyses of the ASCEND-ND and ASCEND-D trials.
Published in:
Nephrology Dialysis Transplantation, 2023, v. 38, n. 8, p. 1890, doi. 10.1093/ndt/gfac342
By:
- Singh, Ajay K;
- McCausland, Finnian R;
- Claggett, Brian L;
- Wanner, Christoph;
- Wiecek, Andrzej;
- Atkins, Michael B;
- Carroll, Kevin;
- Perkovic, Vlado;
- McMurray, John J V;
- Wittes, Janet;
- Snapinn, Steven;
- Blackorby, Allison;
- Meadowcroft, Amy;
- Barker, Tara;
- DiMino, Tara;
- Mallett, Stephen;
- Cobitz, Alexander R;
- Solomon, Scott D
Publication type:
Article
ASCEND-ND trial: study design and participant characteristics.
Published in:
Nephrology Dialysis Transplantation, 2022, v. 37, n. 11, p. 2157, doi. 10.1093/ndt/gfab318
By:
- Perkovic, Vlado;
- Blackorby, Allison;
- Cizman, Borut;
- Carroll, Kevin;
- Cobitz, Alexander R;
- Davies, Rich;
- DiMino, Tara L;
- Jha, Vivekanand;
- Johansen, Kirsten L;
- Lopes, Renato D;
- Kler, Lata;
- Macdougall, Iain C;
- McMurray, John J V;
- Meadowcroft, Amy M;
- Obrador, Gregorio T;
- Solomon, Scott;
- Taft, Lin;
- Wanner, Christoph;
- Waikar, Sushrut S;
- Wheeler, David C
Publication type:
Article
Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial.
Published in:
Nephrology Dialysis Transplantation, 2022, v. 37, n. 5, p. 960, doi. 10.1093/ndt/gfab065
By:
- Singh, Ajay K;
- Blackorby, Allison;
- Cizman, Borut;
- Carroll, Kevin;
- Cobitz, Alexander R;
- Davies, Rich;
- Jha, Vivekanand;
- Johansen, Kirsten L;
- Lopes, Renato D;
- Kler, Lata;
- Macdougall, Iain C;
- McMurray, John J V;
- Meadowcroft, Amy M;
- Obrador, Gregorio T;
- Perkovic, Vlado;
- Solomon, Scott;
- Wanner, Christoph;
- Waikar, Sushrut S;
- Wheeler, David C;
- Wiecek, Andrzej
Publication type:
Article
A randomized, parallel group, double-blind, multicentre study comparing the efficacy and safety of Avandamet (rosiglitazone/metformin) and metformin on long-term glycaemic control and bone mineral density after 80 weeks of treatment in drug-na ïve type 2 diabetes mellitus patients
Published in:
Diabetes, Obesity & Metabolism, 2011, v. 13, n. 11, p. 1036, doi. 10.1111/j.1463-1326.2011.01461.x
By:
- Borges, J. L. C.;
- Bilezikian, J. P.;
- Jones-Leone, A. R.;
- Acusta, A. P.;
- Ambery, P. D.;
- Nino, A. J.;
- Grosse, M.;
- Fitzpatrick, L. A.;
- Cobitz, A. R.
Publication type:
Article
Rosiglitazone decreases bone mineral density and increases bone turnover in postmenopausal women with type 2 diabetes mellitus.
Published in:
2013
By:
- Bilezikian, John P;
- Josse, Robert G;
- Eastell, Richard;
- Lewiecki, E Michael;
- Miller, Colin G;
- Wooddell, Margaret;
- Northcutt, Allison R;
- Kravitz, Barbara G;
- Paul, Gitanjali;
- Cobitz, Alexander R;
- Nino, Antonio J;
- Fitzpatrick, Lorraine A
Publication type:
Journal Article
Anemia and mortality in patients with nondialysis-dependent chronic kidney disease.
Published in:
2018
By:
- Stirnadel-Farrant, Heide A.;
- Luo, Jiacong;
- Kler, Lata;
- Cizman, Borut;
- Jones, Delyth;
- Brunelli, Steven M.;
- Cobitz, Alexander R.
Publication type:
journal article
Posttranslational modification of ras proteins: Detection of a modification prior to fatty acid acylation and cloning of a gene responsible for the modification.
Published in:
Journal of Cellular Biochemistry, 1988, v. 36, n. 3, p. 261, doi. 10.1002/jcb.240360307
By:
- Tamanoi, F.;
- Hsueh, E. C.;
- Goodman, L. E.;
- Cobitz, A. R.;
- Detrick, R. J.;
- Brown, W. R.;
- Fujiyama, A.
Publication type:
Article
Improving Metabolic Control Leads to Better Working Memory in Adults With Type 2 Diabetes.
Published in:
Diabetes Care, 2006, v. 29, n. 2, p. 345, doi. 10.2337/diacare.29.02.06.dc05-1626
By:
- Ryan, Christopher M.;
- Freed, Martin I.;
- Rood, Julie A.;
- Cobitz, Alexander R.;
- Waterhouse, Brian R.;
- Strachan, Mark W. J.
Publication type:
Article
Effect of renal function and dialysis modality on daprodustat and predominant metabolite exposure.
Published in:
Clinical Kidney Journal, 2019, v. 12, n. 5, p. 693, doi. 10.1093/ckj/sfz013
By:
- Caltabiano, Stephen;
- Cizman, Borut;
- Burns, Olivia;
- Mahar, Kelly M;
- Johnson, Brendan M;
- Ramanjineyulu, Bandi;
- Serbest, Gulyeter;
- Cobitz, Alexander R
Publication type:
Article
Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants on hemodialysis.
Published in:
Clinical Kidney Journal, 2019, v. 12, n. 1, p. 139, doi. 10.1093/ckj/sfy014
By:
- Meadowcroft, Amy M;
- Cizman, Borut;
- Holdstock, Louis;
- Biswas, Nandita;
- Johnson, Brendan M;
- Jones, Delyth;
- Nossuli, A Kaldun;
- Lepore, John J;
- Aarup, Michael;
- Cobitz, Alexander R
Publication type:
Article
Daprodustat for anemia: a 24-week, open-label, randomized controlled trial in participants with chronic kidney disease.
Published in:
Clinical Kidney Journal, 2019, v. 12, n. 1, p. 129, doi. 10.1093/ckj/sfy013
By:
- Holdstock, Louis;
- Cizman, Borut;
- Meadowcroft, Amy M;
- Biswas, Nandita;
- Johnson, Brendan M;
- Jones, Delyth;
- Kim, Sung Gyun;
- Zeig, Steven;
- Lepore, John J;
- Cobitz, Alexander R
Publication type:
Article
Normalization of skeletal muscle glycogen synthesis and glycolysis in rosiglitazone-treated Zucker fatty rats: an in vivo nuclear magnetic resonance study.
Published in:
2002
By:
- Jucker, Beat M.;
- Schaeffer, Thomas R.;
- Haimbach, Robin E.;
- McIntosh, Thomas S.;
- Chun, Daniel;
- Mayer, Matthew;
- Ohlstein, Derek H.;
- Davis, Hugh M.;
- Smith, Stephen A.;
- Cobitz, Alexander R.;
- Sarkar, Susanta K.
Publication type:
journal article
Commentary on 'case series of liver failure associated with rosiglitazone and pioglitazone' by Floyd et al.
Published in:
Pharmacoepidemiology & Drug Safety, 2009, v. 18, n. 12, p. 1244, doi. 10.1002/pds.1840
By:
- Osei, Suzette Y;
- Koro, Carol E;
- Cobitz, Alexander R;
- Kolatkar, Nikheel S;
- Stender, Monika
Publication type:
Article
Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D).
Published in:
American Journal of Nephrology, 2023, v. 54, n. 1/2, p. 1, doi. 10.1159/000528696
By:
- Macdougall, Iain C.;
- Meadowcroft, Amy M.;
- Blackorby, Allison;
- Cizman, Borut;
- Cobitz, Alexander R.;
- Godoy, Sergio;
- Jha, Vivekanand;
- Johansen, Kirsten L.;
- McMahon, Gearoid;
- Obrador, Gregorio T.;
- Wong, Muh Geot;
- Singh, Ajay K.
Publication type:
Article
Daprodustat Compared with Epoetin Beta Pegol for Anemia in Japanese Patients Not on Dialysis: A 52-Week Randomized Open-Label Phase 3 Trial.
Published in:
American Journal of Nephrology, 2021, v. 52, n. 1, p. 26, doi. 10.1159/000513103
By:
- Nangaku, Masaomi;
- Hamano, Takayuki;
- Akizawa, Tadao;
- Tsubakihara, Yoshiharu;
- Nagai, Reiko;
- Okuda, Nobuhiko;
- Kurata, Kyo;
- Nagakubo, Takashi;
- Jones, Nigel P.;
- Endo, Yukihiro;
- Cobitz, Alexander R.
Publication type:
Article
A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat, administered three times weekly in patients with anemia on hemodialysis.
Published in:
2019
By:
- Bailey, Christine K.;
- Caltabiano, Stephen;
- Cobitz, Alexander R.;
- Huang, Chun;
- Mahar, Kelly M.;
- Patel, Vickas V.
Publication type:
journal article
Medical Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy: A Consensus Statement of the American Diabetes Association and the European Association for the Study of Diabetes.
Published in:
Diabetes Care, 2009, v. 32, n. 5, p. e58, doi. 10.2337/dc09-0125
By:
- COBITZ, ALEXANDER R.;
- AMBERY, PHIL
Publication type:
Article
Characterization of chronic and acute ESA hyporesponse: a retrospective cohort study of hemodialysis patients.
Published in:
BMC Nephrology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12882-015-0138-x
By:
- Sibbel, Scott P.;
- Koro, Carol E.;
- Brunelli, Steven M.;
- Cobitz, Alexander R.
Publication type:
Article
Characterization of chronic and acute ESA hyporesponse: a retrospective cohort study of hemodialysis patients.
Published in:
2015
By:
- Sibbel, Scott P;
- Koro, Carol E;
- Brunelli, Steven M;
- Cobitz, Alexander R
Publication type:
journal article

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