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Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis.
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- Journal of Neuroscience, 2013, v. 33, n. 11, p. 4657, doi. 10.1523/JNEUROSCI.1119-12.2013
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- Article
Phosphorylation of Highly Conserved Neurofilament Medium KSP Repeats Is Not Required for Myelin-Dependent Radial Axonal Growth.
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- Journal of Neuroscience, 2009, v. 29, n. 5, p. 1277, doi. 10.1523/JNEUROSCI.3765-08.2009
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- Article
Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1.
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- Journal of Neurochemistry, 2008, v. 107, n. 1, p. 253, doi. 10.1111/j.1471-4159.2008.05601.x
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- Article
Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis.
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- Journal of Neurochemistry, 2005, v. 93, n. 4, p. 875, doi. 10.1111/j.1471-4159.2005.03054.x
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- Article
Cell biology: Nondisjunction, aneuploidy and tetraploidy.
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- Nature, 2006, v. 442, n. 7104, p. E9, doi. 10.1038/nature05139
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- Article
Structural determinants for generating centromeric chromatin.
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- Nature, 2004, v. 430, n. 6999, p. 578, doi. 10.1038/nature02766
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- Article
Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS.
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- Molecular Therapy, 2013, v. 21, n. 12, p. 2148, doi. 10.1038/mt.2013.211
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- Article
Cep152 interacts with Plk4 and is required for centriole duplication.
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- Journal of Cell Biology, 2010, v. 191, n. 4, p. 721, doi. 10.1083/jcb.201006049
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- Article
A chemical tool box defines mitotic and interphase roles for Mps1 kinase.
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- Journal of Cell Biology, 2010, v. 190, n. 1, p. 21, doi. 10.1083/jcb.201006080
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- Article
Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability.
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- Journal of Cell Biology, 2010, v. 188, n. 2, p. 191, doi. 10.1083/jcb.200911102
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- Article
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.
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- Journal of Cell Biology, 2009, v. 187, n. 6, p. 761, doi. 10.1083/jcb.200908164
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- Article
The role of aneuploidy in promoting and suppressing tumors.
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- Journal of Cell Biology, 2009, v. 185, n. 6, p. 935, doi. 10.1083/jcb.200905098
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- Article
Requirements for NuMA in maintenance and establishment of mammalian spindle poles.
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- Journal of Cell Biology, 2009, v. 184, n. 5, p. 677, doi. 10.1083/jcb.200810091
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- Article
CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether.
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- Journal of Cell Biology, 2008, v. 181, n. 3, p. 411, doi. 10.1083/jcb.200802189
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- Article
Propagation of centromeric chromatin requires exit from mitosis.
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- Journal of Cell Biology, 2007, v. 176, n. 6, p. 795, doi. 10.1083/jcb.200701066
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- Article
Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling.
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- Journal of Cell Biology, 2005, v. 170, n. 6, p. 873, doi. 10.1083/jcb.200505040
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- Article
ZW10 links mitotic checkpoint signaling to the structural kinetochore.
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- Journal of Cell Biology, 2005, v. 169, n. 1, p. 49, doi. 10.1083/jcb.200411118
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- Article
A standardized kinesin nomenclature.
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- Journal of Cell Biology, 2004, v. 167, n. 1, p. 19, doi. 10.1083/jcb.200408113
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- Article
NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth.
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- Journal of Cell Biology, 2003, v. 163, n. 5, p. 1011, doi. 10.1083/jcb.200308159
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- Article
Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss.
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- Journal of Cell Biology, 2003, v. 162, n. 4, p. 551, doi. 10.1083/jcb.200303167
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- Article
Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A.
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- Journal of Cell Biology, 2003, v. 161, n. 1, p. 55, doi. 10.1083/jcb.200301026
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- Article
Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.
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- Journal of Cell Biology, 2002, v. 158, n. 4, p. 681, doi. 10.1083/jcb.200202037
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- Article
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration.
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- Human Molecular Genetics, 2010, v. 19, n. R1, p. R46, doi. 10.1093/hmg/ddq137
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- Article
Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway.
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- Human Molecular Genetics, 2009, v. 18, n. 8, p. 1384, doi. 10.1093/hmg/ddp044
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- Article
Hindlimb gait defects due to motor axon loss and reduced distal muscles in a transgenic mouse model of Charcot–Marie–Tooth type 2A.
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- Human Molecular Genetics, 2008, v. 17, n. 3, p. 367, doi. 10.1093/hmg/ddm314
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- Article
A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.
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- Nucleic Acids Research, 2024, v. 52, n. 8, p. 4440, doi. 10.1093/nar/gkae216
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- Article
Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition.
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- Nature Communications, 2017, v. 8, n. 6, p. 15775, doi. 10.1038/ncomms15775
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- Article
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.
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- Nature Communications, 2015, v. 6, n. 1, p. 6171, doi. 10.1038/ncomms7171
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- Article
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
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- Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00737-5
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- Article
Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.
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- Acta Neuropathologica, 2021, v. 142, n. 6, p. 985, doi. 10.1007/s00401-021-02374-4
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- Article
Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.
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- Acta Neuropathologica, 2018, v. 136, n. 3, p. 425, doi. 10.1007/s00401-018-1852-9
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- Article
Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
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- Acta Neuropathologica, 2018, v. 135, n. 3, p. 459, doi. 10.1007/s00401-017-1793-8
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- Article
Misfolded SOD1 is not a primary component of sporadic ALS.
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- Acta Neuropathologica, 2017, v. 134, n. 1, p. 97, doi. 10.1007/s00401-017-1688-8
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- Article
Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.
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- Acta Neuropathologica, 2017, v. 133, n. 6, p. 907, doi. 10.1007/s00401-017-1698-6
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- Article
Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72.
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- Acta Neuropathologica, 2015, v. 130, n. 6, p. 863, doi. 10.1007/s00401-015-1480-6
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- Article
Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers.
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- Acta Neuropathologica, 2015, v. 130, n. 4, p. 559, doi. 10.1007/s00401-015-1474-4
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- Article
Neurodegeneration: An expansion in ALS genetics.
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- 2010
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- Publication type:
- Opinion
Motor neuron disease: The curious ways of ALS.
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- Nature, 2008, v. 454, n. 7202, p. 284, doi. 10.1038/454284a
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- Article
Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
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- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0212-4
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- Article
TDP-43 toxicity and the usefulness of junk.
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- Nature Genetics, 2012, v. 44, n. 12, p. 1289, doi. 10.1038/ng.2473
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- Article
The Copper Chaperone CCS Is Abundant in Neurons and Astrocytes in Humanand Rodent Brain.
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- Journal of Neurochemistry, 1999, v. 72, n. 1, p. 422, doi. 10.1046/j.1471-4159.1999.0720422.x
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- Publication type:
- Article
Elevation of tubulin levels by microinjection suppresses new tubulin synthesis.
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- Nature, 1983, v. 305, n. 5936, p. 738, doi. 10.1038/305738a0
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- Publication type:
- Article
Phosphorylation of CENP-A on serine 7 does not control centromere function.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08073-1
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- Publication type:
- Article
TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC.
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- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06774-1
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- Article
Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis.
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- Nature Reviews Molecular Cell Biology, 2009, v. 10, n. 7, p. 478, doi. 10.1038/nrm2718
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- Article
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint.
- Published in:
- Nature Cell Biology, 2000, v. 2, n. 8, p. 484, doi. 10.1038/35019518
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- Publication type:
- Article
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20768-y
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- Publication type:
- Article
Human Neural Stem Cell Replacement Therapy for Amyotrophic Lateral Sclerosis by Spinal Transplantation.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042614
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- Article
Misfolded SOD1 Associated with Motor Neuron Mitochondria Alters Mitochondrial Shape and Distribution Prior to Clinical Onset.
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- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022031
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- Article
Human Condensin Function Is Essential for Centromeric Chromatin Assembly and Proper Sister Kinetochore Orientation.
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- PLoS ONE, 2009, v. 4, n. 8, p. 1, doi. 10.1371/journal.pone.0006831
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- Article