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Incretins in obesity and diabetes.
Published in:
Annals of the New York Academy of Sciences, 2020, v. 1461, n. 1, p. 104, doi. 10.1111/nyas.14211
By:
- Chia, Chee W.;
- Egan, Josephine M.
Publication type:
Article
Plasma Klotho and Frailty in Older Adults: Findings From the InCHIANTI Study.
Published in:
2019
By:
- Shardell, Michelle;
- Semba, Richard D;
- Kalyani, Rita R;
- Bandinelli, Stefania;
- Prather, Aric A;
- Chia, Chee W;
- Ferrucci, Luigi
Publication type:
journal article
Bioavailable Testosterone Linearly Declines Over A Wide Age Spectrum in Men and Women From The Baltimore Longitudinal Study of Aging.
Published in:
2016
By:
- Fabbri, Elisa;
- Yang An;
- Gonzalez-Freire, Marta;
- Zoli, Marco;
- Maggio, Marcello;
- Studenski, Stephanie A.;
- Egan, Josephine M.;
- Chia, Chee W.;
- Ferrucci, Luigi;
- An, Yang
Publication type:
journal article
Free Thyroxine and Functional Mobility, Fitness, and Fatigue in Euthyroid Older Men and Women in the Baltimore Longitudinal Study of Aging.
Published in:
2016
By:
- Simonsick, Eleanor M.;
- Chia, Chee W.;
- Mammen, Jennifer S.;
- Egan, Josephine M.;
- Ferrucci, Luigi
Publication type:
journal article
Plasma Klotho and Cognitive Decline in Older Adults: Findings From the InCHIANTI Study.
Published in:
2016
By:
- Shardell, Michelle;
- Semba, Richard D.;
- Rosano, Caterina;
- Kalyani, Rita R.;
- Bandinelli, Stefania;
- Chia, Chee W.;
- Ferrucci, Luigi
Publication type:
journal article
Glucose and Insulin Measurements From the Oral Glucose Tolerance Test and Relationship to Muscle Mass.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67A, n. 1, p. 74, doi. 10.1093/gerona/glr022
By:
- Kalyani, Rita R.;
- Metter, E. Jeffrey;
- Ramachandran, Ramona;
- Chia, Chee W.;
- Saudek, Christopher D.;
- Ferrucci, Luigi
Publication type:
Article
Heterogeneity and transcriptome changes of human CD8<sup>+</sup> T cells across nine decades of life.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32869-x
By:
- Lu, Jian;
- Ahmad, Raheel;
- Nguyen, Thomas;
- Cifello, Jeffrey;
- Hemani, Humza;
- Li, Jiangyuan;
- Chen, Jinguo;
- Li, Siyi;
- Wang, Jing;
- Achour, Achouak;
- Chen, Joseph;
- Colie, Meagan;
- Lustig, Ana;
- Dunn, Christopher;
- Zukley, Linda;
- Chia, Chee W.;
- Burd, Irina;
- Zhu, Jun;
- Ferrucci, Luigi;
- Weng, Nan-ping
Publication type:
Article
Evidence for brain glucose dysregulation in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 3, p. 318, doi. 10.1016/j.jalz.2017.09.011
By:
- An, Yang;
- Varma, Vijay R.;
- Varma, Sudhir;
- Casanova, Ramon;
- Dammer, Eric;
- Pletnikova, Olga;
- Chia, Chee W.;
- Egan, Josephine M.;
- Ferrucci, Luigi;
- Troncoso, Juan;
- Levey, Allan I.;
- Lah, James;
- Seyfried, Nicholas T.;
- Legido‐Quigley, Cristina;
- O'Brien, Richard;
- Thambisetty, Madhav
Publication type:
Article
Skeletal muscle transcriptome in healthy aging.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22168-2
By:
- Tumasian III, Robert A.;
- Harish, Abhinav;
- Kundu, Gautam;
- Yang, Jen-Hao;
- Ubaida-Mohien, Ceereena;
- Gonzalez-Freire, Marta;
- Kaileh, Mary;
- Zukley, Linda M.;
- Chia, Chee W.;
- Lyashkov, Alexey;
- Wood III, William H.;
- Piao, Yulan;
- Coletta, Christopher;
- Ding, Jun;
- Gorospe, Myriam;
- Sen, Ranjan;
- De, Supriyo;
- Ferrucci, Luigi
Publication type:
Article
Role and development of GLP-1 receptor agonists in the management of diabetes.
Published in:
Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2009, v. 2, p. 37
By:
- Chia, Chee W.;
- Egan, Josephine M.
Publication type:
Article
Nonlinear modeling of oral glucose tolerance test response to evaluate associations with aging outcomes.
Published in:
PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0302381
By:
- Schumock, Grant;
- Bandeen-Roche, Karen;
- Chia, Chee W.;
- Kalyani, Rita R.;
- Ferrucci, Luigi;
- Varadhan, Ravi
Publication type:
Article
Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in Older Men.
Published in:
2016
By:
- Dias, Jenny Pena;
- Melvin, Denise;
- Shardell, Michelle;
- Ferrucci, Luigi;
- Chia, Chee W;
- Gharib, Mohsen;
- Egan, Josephine M;
- Basaria, Shehzad
Publication type:
journal article
GIP contributes to islet trihormonal abnormalities in type 2 diabetes.
Published in:
2014
By:
- Chia, Chee W;
- Odetunde, Juliana O;
- Kim, Wook;
- Carlson, Olga D;
- Ferrucci, Luigi;
- Egan, Josephine M
Publication type:
journal article
Cross-sectional evidence of a signaling pathway from bone homeostasis to glucose metabolism.
Published in:
2011
By:
- Gravenstein, Kristofer S;
- Napora, Joshua K;
- Short, Ryan G;
- Ramachandran, Ramona;
- Carlson, Olga D;
- Metter, E Jeffrey;
- Ferrucci, Luigi;
- Egan, Josephine M;
- Chia, Chee W
Publication type:
journal article
Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets.
Published in:
Diabetologia, 2018, v. 61, n. 6, p. 1470, doi. 10.1007/s00125-018-4576-4
By:
- González-Mariscal, Isabel;
- Montoro, Rodrigo A.;
- Doyle, Máire E.;
- Liu, Qing-Rong;
- Rouse, Michael;
- O’Connell, Jennifer F.;
- Santa-Cruz Calvo, Sara;
- Krzysik-Walker, Susan M.;
- Ghosh, Soumita;
- Carlson, Olga D.;
- Lehrmann, Elin;
- Zhang, Yongqing;
- Becker, Kevin G.;
- Chia, Chee W.;
- Ghosh, Paritosh;
- Egan, Josephine M.
Publication type:
Article
Regular low‐calorie sweetener consumption is associated with increased secretion of glucose‐dependent insulinotropic polypeptide.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 9, p. 2282, doi. 10.1111/dom.13328
By:
- Chia, Chee W.;
- Shardell, Michelle;
- Gravenstein, Kristofer S.;
- Carlson, Olga D.;
- Simonsick, Eleanor M.;
- Ferrucci, Luigi;
- Egan, Josephine M.
Publication type:
Article
SARS-CoV-2 infection establishes a stable and age-independent CD8<sup>+</sup> T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42430-z
By:
- Choy, Cecily;
- Chen, Joseph;
- Li, Jiangyuan;
- Gallagher, D. Travis;
- Lu, Jian;
- Wu, Daichao;
- Zou, Ainslee;
- Hemani, Humza;
- Baptiste, Beverly A.;
- Wichmann, Emily;
- Yang, Qian;
- Ciffelo, Jeffrey;
- Yin, Rui;
- McKelvy, Julia;
- Melvin, Denise;
- Wallace, Tonya;
- Dunn, Christopher;
- Nguyen, Cuong;
- Chia, Chee W.;
- Fan, Jinshui
Publication type:
Article
Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease.
Published in:
Frontiers in Aging Neuroscience, 2017, v. 9, p. 1, doi. 10.3389/fnagi.2017.00118
By:
- Mullins, Roger J.;
- Diehl, Thomas C.;
- Chia, Chee W.;
- Kapogiannis, Dimitrios
Publication type:
Article
Incretin-based therapies in type 2 diabetes mellitus.
Published in:
2008
By:
- Chia, Chee W;
- Egan, Josephine M
Publication type:
journal article
The Diagnosis of Fasting Hypoglycemia Due to an Islet-Cell Tumor Obscured by a Highly Specific Insulin Assay.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 4, p. 1464, doi. 10.1210/jc.2002-021543
By:
- CHIA, CHEE W.;
- SAUDEK, CHRISTOPHER D.
Publication type:
Article
Body Mass Index and Diabetes Incidence Across the Adult Lifespan: The Baltimore Longitudinal Study of Aging.
Published in:
Journal of the Endocrine Society, 2024, v. 8, n. 11, p. 1, doi. 10.1210/jendso/bvae156
By:
- Malandrino, Noemi;
- Metter, E Jeffrey;
- Simonsick, Eleanor M;
- Egan, Josephine M;
- Chia, Chee W;
- Walston, Jeremy D;
- Ferrucci, Luigi;
- Kalyani, Rita R
Publication type:
Article
The Relationship of Lean Body Mass With Aging to the Development of Diabetes.
Published in:
Journal of the Endocrine Society, 2020, v. 4, n. 7, p. 1, doi. 10.1210/jendso/bvaa043
By:
- Kalyani, Rita R;
- Metter, E Jeffrey;
- Xue, Qian-Li;
- Egan, Josephine M;
- Chia, Chee W;
- Studenski, Stephanie;
- Shaffer, Nancy Chiles;
- Golden, Sherita;
- Al-Sofiani, Mohammed;
- Florez, Hermes;
- Ferrucci, Luigi
Publication type:
Article
Effect of Rifaximin Treatment on Endotoxemia and Insulin Sensitivity in Humans.
Published in:
Journal of the Endocrine Society, 2019, v. 3, n. 9, p. 1641, doi. 10.1210/js.2019-00148
By:
- Finlin, Brian S;
- Zhu, Beibei;
- Boyechko, Tania;
- Westgate, Philip M;
- Chia, Chee W;
- Egan, Josephine M;
- Kern, Philip A
Publication type:
Article
Chronic Low-Calorie Sweetener Use and Risk of Abdominal Obesity among Older Adults: A Cohort Study.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167241
By:
- Chia, Chee W.;
- Shardell, Michelle;
- Tanaka, Toshiko;
- Liu, David D.;
- Gravenstein, Kristofer S.;
- Simonsick, Eleanor M.;
- Egan, Josephine M.;
- Ferrucci, Luigi
Publication type:
Article
Intravenous GIP Worsens Postprandial Hyperglycemia in Humans with Type 2 Diabetes.
Published in:
Diabetes, 2007, v. 56, p. A385
By:
- Chia, Chee W.;
- Carlson, Olga;
- Melvin, Denise;
- Kim, Heeseung;
- Tagalicud, Arlene;
- Charles, Cornelia;
- Egan, Josephine M.
Publication type:
Article
Thyroid Hormone Therapy and Risk of Thyrotoxicosis in Community-Resident Older Adults: Findings from the Baltimore Longitudinal Study of Aging.
Published in:
Thyroid, 2015, v. 25, n. 9, p. 979, doi. 10.1089/thy.2015.0180
By:
- Mammen, Jennifer S.;
- McGready, John;
- Oxman, Rachael;
- Chia, Chee W.;
- Ladenson, Paul W.;
- Simonsick, Eleanor M.
Publication type:
Article
Physical Activity Associated Proteomics of Skeletal Muscle: Being Physically Active in Daily Life May Protect Skeletal Muscle From Aging.
Published in:
Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00312
By:
- Ubaida-Mohien, Ceereena;
- Gonzalez-Freire, Marta;
- Lyashkov, Alexey;
- Moaddel, Ruin;
- Chia, Chee W.;
- Simonsick, Eleanor M.;
- Sen, Ranjan;
- Ferrucci, Luigi
Publication type:
Article
Altered Plasma Amino Acids and Lipids Associated With Abnormal Glucose Metabolism and Insulin Resistance in Older Adults.
Published in:
2018
By:
- Semba, Richard D;
- Gonzalez-Freire, Marta;
- Moaddel, Ruin;
- Sun, Kai;
- Fabbri, Elisa;
- Zhang, Pingbo;
- Carlson, Olga D;
- Khadeer, Mohammed;
- Chia, Chee W;
- Salem, Norman Jr;
- Ferrucci, Luigi
Publication type:
journal article
Cross‐sectional analysis of healthy individuals across decades: Aging signatures across multiple physiological compartments.
Published in:
Aging Cell, 2024, v. 23, n. 1, p. 1, doi. 10.1111/acel.13902
By:
- Moaddel, Ruin;
- Ubaida‐Mohien, Ceereena;
- Tanaka, Toshiko;
- Tian, Qu;
- Candia, Julián;
- Moore, Ann Zenobia;
- Lovett, Jacqueline;
- Fantoni, Giovanna;
- Shehadeh, Nader;
- Turek, Lisa;
- Collingham, Victoria;
- Kaileh, Mary;
- Chia, Chee W.;
- Sen, Ranjan;
- Egan, Josephine M.;
- Ferrucci, Luigi
Publication type:
Article
Transcriptomes of human primary skin fibroblasts of healthy individuals reveal age‐associated mRNAs and long noncoding RNAs.
Published in:
Aging Cell, 2023, v. 22, n. 11, p. 1, doi. 10.1111/acel.13915
By:
- Tsitsipatis, Dimitrios;
- Martindale, Jennifer L.;
- Mazan‐Mamczarz, Krystyna;
- Herman, Allison B.;
- Piao, Yulan;
- Banskota, Nirad;
- Yang, Jen‐Hao;
- Cui, Linna;
- Anerillas, Carlos;
- Chang, Ming‐Wen;
- Kaileh, Mary;
- Munk, Rachel;
- Yang, Xiaoling;
- Ubaida‐Mohien, Ceereena;
- Chia, Chee W.;
- Karikkineth, Ajoy C.;
- Zukley, Linda;
- D'Agostino, Jarod;
- Abdelmohsen, Kotb;
- Basisty, Nathan
Publication type:
Article
Whole‐genome methylation analysis of aging human tissues identifies age‐related changes in developmental and neurological pathways.
Published in:
Aging Cell, 2023, v. 22, n. 7, p. 1, doi. 10.1111/acel.13847
By:
- Tharakan, Ravi;
- Ubaida‐Mohien, Ceereena;
- Dunn, Christopher;
- Kaileh, Mary;
- Tryggvadottir, Rakel;
- Zukley, Linda;
- Chia, Chee W.;
- Sen, Ranjan;
- Ferrucci, Luigi
Publication type:
Article
Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span.
Published in:
Aging Cell, 2022, v. 21, n. 5, p. 1, doi. 10.1111/acel.13609
By:
- Tsitsipatis, Dimitrios;
- Martindale, Jennifer L.;
- Ubaida‐Mohien, Ceereena;
- Lyashkov, Alexey;
- Yanai, Hagai;
- Kashyap, Amogh;
- Shin, Chang Hoon;
- Herman, Allison B.;
- Ji, Eunbyul;
- Yang, Jen‐Hao;
- Munk, Rachel;
- Dunn, Christopher;
- Lukyanenko, Yevgeniya;
- Yang, Xiaoling;
- Chia, Chee W.;
- Karikkineth, Ajoy C.;
- Zukley, Linda;
- D'Agostino, Jarod;
- Kaileh, Mary;
- Cui, Chang‐Yi
Publication type:
Article
Age‐associated expression of p21and p53 during human wound healing.
Published in:
Aging Cell, 2021, v. 20, n. 5, p. 1, doi. 10.1111/acel.13354
By:
- Chia, Chee W.;
- Sherman‐Baust, Cheryl A.;
- Larson, Sara A.;
- Pandey, Ritu;
- Withers, Roxanne;
- Karikkineth, Ajoy C.;
- Zukley, Linda M.;
- Campisi, Judith;
- Egan, Josephine M.;
- Sen, Ranjan;
- Ferrucci, Luigi
Publication type:
Article
Skewed macrophage polarization in aging skeletal muscle.
Published in:
Aging Cell, 2019, v. 18, n. 6, p. N.PAG, doi. 10.1111/acel.13032
By:
- Cui, Chang‐Yi;
- Driscoll, Riley K.;
- Piao, Yulan;
- Chia, Chee W.;
- Gorospe, Myriam;
- Ferrucci, Luigi
Publication type:
Article
Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging.
Published in:
Aging Cell, 2018, v. 17, n. 2, p. 1, doi. 10.1111/acel.12725
By:
- Gonzalez‐Freire, Marta;
- Scalzo, Paul;
- D'Agostino, Jarod;
- Moore, Zenobia A.;
- Diaz‐Ruiz, Alberto;
- Fabbri, Elisa;
- Zane, Ariel;
- Chen, Brian;
- Becker, Kevin G.;
- Lehrmann, Elin;
- Zukley, Linda;
- Chia, Chee W.;
- Tanaka, Toshiko;
- Coen, Paul M.;
- Bernier, Michel;
- de Cabo, Rafael;
- Ferrucci, Luigi
Publication type:
Article
Circulating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54-96 years from the Baltimore Longitudinal Study of Aging.
Published in:
Aging Cell, 2016, v. 15, n. 5, p. 825, doi. 10.1111/acel.12491
By:
- Fabbri, Elisa;
- Yang, An;
- Simonsick, Eleanor M.;
- Chia, Chee W.;
- Zoli, Marco;
- Haughey, Norman J.;
- Mielke, Michelle M.;
- Ferrucci, Luigi;
- Coen, Paul M.
Publication type:
Article
The gut microbiome and regional fat distribution: Findings from the Baltimore Longitudinal Study of Aging.
Published in:
Obesity (19307381), 2023, v. 31, n. 5, p. 1425, doi. 10.1002/oby.23717
By:
- Tilves, Curtis;
- Tanaka, Toshiko;
- Differding, Moira K.;
- Spira, Adam P.;
- Chia, Chee W.;
- Ferrucci, Luigi;
- Mueller, Noel T.
Publication type:
Article
Quality Specific Associations of Carbohydrate Consumption and Frailty Index.
Published in:
Nutrients, 2022, v. 14, n. 23, p. 5072, doi. 10.3390/nu14235072
By:
- Tanaka, Toshiko;
- Kafyra, Maria;
- Jin, Yichen;
- Chia, Chee W.;
- Dedoussis, George V.;
- Talegawkar, Sameera A.;
- Ferrucci, Luigi
Publication type:
Article
Selective Contribution of Regional Adiposity, Skeletal Muscle, and Adipokines to Glucose Disposal in Older Adults.
Published in:
Journal of the American Geriatrics Society, 2012, v. 60, n. 4, p. 707, doi. 10.1111/j.1532-5415.2011.03865.x
By:
- Ramachandran, Ramona;
- Gravenstein, Kristofer S.;
- Metter, E. Jeffrey;
- Egan, Josephine M.;
- Ferrucci, Luigi;
- Chia, Chee W.
Publication type:
Article
Novel Human Insulin Isoforms and Cα-Peptide Product in Islets of Langerhans and Choroid Plexus.
Published in:
2021
By:
- Liu, Qing-Rong;
- Zhu, Min;
- Zhang, Pingbo;
- Mazucanti, Caio H.;
- Huang, Nicholas S.;
- Lang, Doyle L.;
- Chen, Qinghua;
- Auluck, Pavan;
- Marenco, Stefano;
- O'Connell, Jennifer F.;
- Ferrucci, Luigi;
- Chia, Chee W.;
- Egan, Josephine M.
Publication type:
journal article
1719-P: Novel Mass Spectrometry–Based Selected Reaction Monitoring Proteomics for Analysis of Low Abundant Insulin Levels in Cerebrospinal Fluid.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1719-P
By:
- LIU, QING-RONG;
- ZHU, MIN;
- CHIA, CHEE W.;
- O'CONNELL, JENNIFER F.;
- ZHANG, PINGBO;
- EGAN, JOSEPHINE M.
Publication type:
Article
Insulin Resistance Is Associated With Reduced Mitochondrial Oxidative Capacity Measured by 31P-Magnetic Resonance Spectroscopy in Participants Without Diabetes From the Baltimore Longitudinal Study of Aging.
Published in:
2017
By:
- Fabbri, Elisa;
- Chia, Chee W.;
- Spencer, Richard G.;
- Fishbein, Kenneth W.;
- Reiter, David A.;
- Cameron, Donnie;
- Zane, Ariel C.;
- Moore, Zenobia A.;
- Gonzalez-Freire, Marta;
- Zoli, Marco;
- Studenski, Stephanie A.;
- Kalyani, Rita R.;
- Egan, Josephine M.;
- Ferrucci, Luigi
Publication type:
journal article
Incretin Therapy and Pancreatic Pathologies: Background Pathology Versus Drug-Induced Pathology in Rats.
Published in:
2014
By:
- Egan, Josephine M.;
- Chia, Chee W.
Publication type:
Opinion
Exogenous glucose-dependent insulinotropic polypeptide worsens post prandial hyperglycemia in type 2 diabetes.
Published in:
2009
By:
- Chia CW;
- Carlson OD;
- Kim W;
- Shin YK;
- Charles CP;
- Kim HS;
- Melvin DL;
- Egan JM;
- Chia, Chee W;
- Carlson, Olga D;
- Kim, Wook;
- Shin, Yu-Kyong;
- Charles, Cornelia P;
- Kim, Hee Seung;
- Melvin, Denise L;
- Egan, Josephine M
Publication type:
journal article
Exogenous Glucose-Dependent Insulinotropic Polypeptide Worsens Postprandial Hyperglycemia in Type 2 Diabetes.
Published in:
Diabetes, 2009, v. 58, n. 6, p. 1342, doi. 10.2337/db08-0958
By:
- Chia, Chee W.;
- Carlson, Olga D.;
- Wook Kim;
- Yu-Kyong Shin;
- Charles, Cornelia P.;
- Hee Seung Kim;
- Melvin, Denise L.;
- Egan, Josephine M.
Publication type:
Article

Found: 45