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The Promise of Patient-Derived Preclinical Models to Accelerate the Implementation of Personalised Medicine for Children with Neuroblastoma.
Published in:
Journal of Personalized Medicine, 2021, v. 11, n. 4, p. 248, doi. 10.3390/jpm11040248
By:
- Tucker, Elizabeth R.;
- George, Sally;
- Angelini, Paola;
- Bruna, Alejandra;
- Chesler, Louis
Publication type:
Article
Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer.
Published in:
Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00111
By:
- Cage, Tene Aneka;
- Yvan Chanthery;
- Chesler, Louis;
- Grimmer, Matthew;
- Knight, Zachary;
- Shokat, Kevan;
- Weiss, William A.;
- Gustafson, W. Clay
Publication type:
Article
The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma.
Published in:
Science Signaling, 2014, v. 7, n. 349, p. 1, doi. 10.1126/scisignal.2005470
By:
- Umapathy, Ganesh;
- El Wakil, Abeer;
- Witek, Barbara;
- Chesler, Louis;
- Danielson, Laura;
- Xianming Deng;
- Gray, Nathanael S.;
- Johansson, Mikael;
- Kvarnbrink, Samuel;
- Ruuth, Kristina;
- Schönherr, Christina;
- Palmer, Ruth H.;
- Hallberg, Bengt
Publication type:
Article
Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119834
By:
- Ahmad, Zai;
- Jasnos, Lukasz;
- Gil, Veronica;
- Howell, Louise;
- Hallsworth, Albert;
- Petrie, Kevin;
- Sawado, Tomoyuki;
- Chesler, Louis
Publication type:
Article
Intrinsic Susceptibility MRI Identifies Tumors with ALKF1174L Mutation in Genetically-Engineered Murine Models of High-Risk Neuroblastoma.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092886
By:
- Jamin, Yann;
- Glass, Laura;
- Hallsworth, Albert;
- George, Rani;
- Koh, Dow-Mu;
- Pearson, Andrew D. J.;
- Chesler, Louis;
- Robinson, Simon P.
Publication type:
Article
miRNA Expression Profiling of the Murine TH-MYCN Neuroblastoma Model Reveals Similarities with Human Tumors and Identifies Novel Candidate MiRNAs.
Published in:
PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028356
By:
- Terrile, Marta;
- Bryan, Kenneth;
- Vaughan, Lynsey;
- Hallsworth, Albert;
- Webber, Hannah;
- Chesler, Louis;
- Stallings, Raymond L.
Publication type:
Article
Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
Published in:
Journal of Cellular Biochemistry, 2007, v. 102, n. 6, p. 1529, doi. 10.1002/jcb.21373
By:
- Meyer, Gary E.;
- Chesler, Louis;
- Liu, Dandan;
- Gable, Karissa;
- Maddux, Betty A.;
- Goldenberg, David D.;
- Youngren, Jack F.;
- Goldfine, Ira D.;
- Weiss, William A.;
- Matthay, Katherine K.;
- Rosenthal, Stephen M.
Publication type:
Article
Henoch-Schönlein purpura with severe jejunitis and minimal skin lesions.
Published in:
2000
By:
- Chesler, Louis;
- Hwang, Linda;
- Patton, Wendy;
- Heyman, Melvin B.;
- Chesler, L;
- Hwang, L;
- Patton, W;
- Heyman, M B
Publication type:
journal article
Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on-target ALK inhibitors in neuroblastoma.
Published in:
Molecular Oncology, 2017, v. 11, n. 8, p. 996, doi. 10.1002/1878-0261.12069
By:
- Tucker, Elizabeth R.;
- Tall, Jennifer R.;
- Danielson, Laura S.;
- Gowan, Sharon;
- Jamin, Yann;
- Robinson, Simon P.;
- Banerji, Udai;
- Chesler, Louis
Publication type:
Article
Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead.
Published in:
Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.694320
By:
- Shrestha, Sumana;
- Morcavallo, Alaide;
- Gorrini, Chiara;
- Chesler, Louis
Publication type:
Article
Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma.
Published in:
Brain Pathology, 2018, v. 28, n. 4, p. 475, doi. 10.1111/bpa.12525
By:
- Boult, Jessica K. R.;
- Apps, John R.;
- Hölsken, Annett;
- Hutchinson, J. Ciaran;
- Carreno, Gabriela;
- Danielson, Laura S.;
- Smith, Laura M.;
- Bäuerle, Tobias;
- Buslei, Rolf;
- Buchfelder, Michael;
- Virasami, Alex K.;
- Koers, Alexander;
- Arthurs, Owen J.;
- Jacques, Thomas S.;
- Chesler, Louis;
- Martinez‐Barbera, Juan Pedro;
- Robinson, Simon P.
Publication type:
Article
Pre-clinical imaging of transgenic mouse models of neuroblastoma using a dedicated 3-element solenoid coil on a clinical 3T platform.
Published in:
2017
By:
- Almeida, Gilberto S;
- Panek, Rafal;
- Hallsworth, Albert;
- Webber, Hannah;
- Papaevangelou, Efthymia;
- Boult, Jessica KR;
- Jamin, Yann;
- Chesler, Louis;
- Robinson, Simon P
Publication type:
journal article
18F-meta-fluorobenzylguanidine (18F-mFBG) to monitor changes in norepinephrine transporter expression in response to therapeutic intervention in neuroblastoma models.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77788-3
By:
- Turnock, Stephen;
- Turton, David R.;
- Martins, Carlos Daniel;
- Chesler, Louis;
- Wilson, Thomas C.;
- Gouverneur, Véronique;
- Smith, Graham;
- Kramer-Marek, Gabriela
Publication type:
Article
Inhibition of angiogenesis by tissue inhibitor of metalloproteinase.
Published in:
Journal of Cellular Physiology, 1994, v. 160, n. 1, p. 194, doi. 10.1002/jcp.1041600122
By:
- Johnson, Mark D.;
- Kim, Hyeong-Reh Choi;
- Chesler, Louis;
- Tsao-Wu, Gladys;
- Polverini, Peter J.;
- Bouck, Noel
Publication type:
Article
Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03512-5
By:
- Malagon, Sandra G. Gonzalez;
- Muñoz, Anna M. Lopez;
- Doro, Daniel;
- Bolger, Triòna G.;
- Poon, Evon;
- Tucker, Elizabeth R.;
- Al-Lami, Hadeel Adel;
- Krause, Matthias;
- Phiel, Christopher J.;
- Chesler, Louis;
- Liu, Karen J.
Publication type:
Article
Paraneoplasia, cancer development and immunity: what are the connections?
Published in:
Nature Reviews Cancer, 2014, v. 14, n. 7, p. 447, doi. 10.1038/nrc3766
By:
- Chesler, Louis
Publication type:
Article
Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma.
Published in:
Molecular Oncology, 2016, v. 10, n. 4, p. 538, doi. 10.1016/j.molonc.2015.11.005
By:
- Smith, Jennifer R.;
- Moreno, Lucas;
- Heaton, Simon P.;
- Chesler, Louis;
- Pearson, Andrew D.J.;
- Garrett, Michelle D.
Publication type:
Article
Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma.
Published in:
Molecular Oncology, 2015, v. 9, n. 7, p. 1484, doi. 10.1016/j.molonc.2015.04.005
By:
- Cheung, Belamy B.;
- Tan, Owen;
- Koach, Jessica;
- Liu, Bing;
- Shum, Michael S.Y.;
- Carter, Daniel R.;
- Sutton, Selina;
- Po'uha, Sela T.;
- Chesler, Louis;
- Haber, Michelle;
- Norris, Murray D.;
- Kavallaris, Maria;
- Liu, Tao;
- O'Neill, Geraldine M.;
- Marshall, Glenn M.
Publication type:
Article

Found: 18

The Promise of Patient-Derived Preclinical Models to Accelerate the Implementation of Personalised Medicine for Children with Neuroblastoma.

Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer.

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma.

Molecular and In Vivo Characterization of Cancer-Propagating Cells Derived from MYCN-Dependent Medulloblastoma.

Intrinsic Susceptibility MRI Identifies Tumors with <i>ALK<sup>F1174L</sup></i> Mutation in Genetically-Engineered Murine Models of High-Risk Neuroblastoma.

miRNA Expression Profiling of the Murine TH-MYCN Neuroblastoma Model Reveals Similarities with Human Tumors and Identifies Novel Candidate MiRNAs.

Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.

Henoch-Schönlein purpura with severe jejunitis and minimal skin lesions.

Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on-target ALK inhibitors in neuroblastoma.

Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead.

Preclinical transgenic and patient‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma.

Pre-clinical imaging of transgenic mouse models of neuroblastoma using a dedicated 3-element solenoid coil on a clinical 3T platform.

<sup>18</sup>F-meta-fluorobenzylguanidine (<sup>18</sup>F-mFBG) to monitor changes in norepinephrine transporter expression in response to therapeutic intervention in neuroblastoma models.

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase.

Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus.

Paraneoplasia, cancer development and immunity: what are the connections?

Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma.

Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma.