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Thiol-Reactive Analogues of Galanthamine, Codeine, and Morphine as Potential Probes to Interrogate Allosteric Binding within Nicotinic Acetylcholine Receptors.
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- Australian Journal of Chemistry, 2015, v. 68, n. 12, p. 1834, doi. 10.1071/CH15475
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- Article
Probing the Mode of Neurotransmitter Binding to GABA Receptors Using Selectively Fluorinated GABA Analogues.
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- Australian Journal of Chemistry, 2015, v. 68, n. 1, p. 23, doi. 10.1071/CH14456
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- Article
Correlations of receptor desensitization of gain-of-function GABRB3 variants with clinical severity.
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- Brain: A Journal of Neurology, 2024, v. 147, n. 1, p. 224, doi. 10.1093/brain/awad285
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- Article
Innate Immunity and Inflammation Post-Stroke: An α7-Nicotinic Agonist Perspective.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 12, p. 29029, doi. 10.3390/ijms161226141
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- Article
Pharmacological Effect of GABA Analogues on GABA-ρ2 Receptors and Their Subtype Selectivity.
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- Life (2075-1729), 2022, v. 12, n. 1, p. 127, doi. 10.3390/life12010127
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- Publication type:
- Article
trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and (±)-trans-2-aminomethylcyclopropanecarboxylic acid ((±)-TAMP) can differentiate rat ρ3 from human ρ1 and ρ2 recombinant GABA[subc] receptors.
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- British Journal of Pharmacology, 2002, v. 135, n. 4, p. 883, doi. 10.1038/sj.bjp.0704432
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- Publication type:
- Article
Analogues of γ-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) substituted in the 2 position as GABA<sub>C</sub> receptor antagonists.
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- British Journal of Pharmacology, 1997, v. 122, n. 8, p. 1551, doi. 10.1038/sj.bjp.0701533
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- Article
Gain-of-function and loss-of-function GABRB3 variants lead to distinct clinical phenotypes in patients with developmental and epileptic encephalopathies.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29280-x
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- Article
A Molecular Basis for Agonist and Antagonist Actions at GABA<sub>C</sub> Receptors.
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- Chemical Biology & Drug Design, 2008, v. 71, n. 4, p. 306, doi. 10.1111/j.1747-0285.2008.00642.x
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- Article
Zolpidem is a potent stoichiometry-selective modulator of α1β3 GABA<sub>A</sub> receptors: evidence of a novel benzodiazepine site in the α1-α1 interface.
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- Scientific Reports, 2016, p. 28674, doi. 10.1038/srep28674
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- Article
THE ‘ABC’ OF GABA RECEPTORS: A BRIEF REVIEW.
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- Clinical & Experimental Pharmacology & Physiology, 1999, v. 26, n. 11, p. 937, doi. 10.1046/j.1440-1681.1999.03151.x
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- Article
The Direct Actions of GABA, 2’-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABA<sub>A</sub> Receptors: Evidence for Receptors with Different Subunit Stoichiometries.
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- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141359
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- Article
GABA<sub>A</sub> Receptors Containing ρ1 Subunits Contribute to <i>In Vivo</i> Effects of Ethanol in Mice.
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- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085525
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- Article
Potency of GABA at human recombinant GABA receptors expressed in Xenopus oocytes: a mini review.
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- Amino Acids, 2013, v. 44, n. 4, p. 1139, doi. 10.1007/s00726-012-1456-y
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- Article
Targeting GABA C Receptors Improves Post-Stroke Motor Recovery.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 3, p. 315, doi. 10.3390/brainsci11030315
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- Article
The Z-Drugs Zolpidem, Zaleplon, and Eszopiclone Have Varying Actions on Human GABA<sub> A </sub> Receptors Containing γ1, γ2, and γ3 Subunits.
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- Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.599812
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- Article
The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia.
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- Journal of Cerebral Blood Flow & Metabolism, 2019, v. 39, n. 7, p. 1266, doi. 10.1177/0271678X18755628
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- Article
The de novo GABRA4 p.Thr300Ile variant found in a patient with early‐onset intractable epilepsy and neurodevelopmental abnormalities displays gain‐of‐function traits.
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- Epilepsia (Series 4), 2022, v. 63, n. 9, p. 2439, doi. 10.1111/epi.17358
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- Article
Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions.
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- Epilepsia (Series 4), 2019, v. 60, n. 11, p. 2224, doi. 10.1111/epi.16355
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- Article
The Synthesis and Evaluation of Fluoro-, Trifluoromethyl-, and Iodomuscimols as GABA Agonists.
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- Chemistry - A European Journal, 2017, v. 23, n. 45, p. 10848, doi. 10.1002/chem.201701443
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- Article
Vinpocetine improved neuropsychiatric and epileptic outcomes in a patient with a GABRA1 loss‐of‐function variant.
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- 2023
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- Publication type:
- Case Study
Modulation of Ionotropic GABA Receptors by 6-Methoxyflavanone and 6-Methoxyflavone.
- Published in:
- Neurochemical Research, 2014, v. 39, n. 6, p. 1068, doi. 10.1007/s11064-013-1157-2
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- Article
Neurochemicals for the Investigation of GABA Receptors.
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- Neurochemical Research, 2010, v. 35, n. 12, p. 1970, doi. 10.1007/s11064-010-0271-7
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- Publication type:
- Article
Guanidino Acids Act as ρ1 GABA<sub>C</sub> Receptor Antagonists.
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- Neurochemical Research, 2009, v. 34, n. 10, p. 1704, doi. 10.1007/s11064-009-9968-x
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- Article
The Flavonoid Glycosides, Myricitrin, Gossypin and Naringin Exert Anxiolytic Action in Mice.
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- Neurochemical Research, 2009, v. 34, n. 10, p. 1867, doi. 10.1007/s11064-009-9969-9
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- Article
Pinnatoxins E, F and G target multiple nicotinic receptor subtypes.
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- Journal of Neurochemistry, 2015, v. 135, n. 3, p. 479, doi. 10.1111/jnc.13245
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- Article
rho<sub>1</sub> GABA<sub>C</sub> receptors are expressed in fibrous and cartilaginous layers of chick sclera and located on sclera fibroblasts and chondrocytes.
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- Journal of Neurochemistry, 2011, v. 118, n. 2, p. 281, doi. 10.1111/j.1471-4159.2011.07300.x
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- Article
Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis.
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- 2015
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- Publication type:
- journal article
Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy.
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- British Journal of Pharmacology, 2021, v. 178, n. 24, p. 4826, doi. 10.1111/bph.15661
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- Article
Efficient expression of concatenated α1β2δ and α1β3δ GABA<sub>A</sub> receptors, their pharmacology and stoichiometry.
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- 2021
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- journal article
Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors.
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- 2018
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- Publication type:
- journal article
GABA-ρ receptors: distinctive functions and molecular pharmacology.
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- 2017
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- Publication type:
- journal article
Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State.
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- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161154
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- Article
Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABA<sub>A</sub> Receptors: Functional Characteristics and Molecular Mechanism.
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- PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0157700
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- Article
Investigating the Role of Loop C Hydrophilic Residue ‘T244’ in the Binding Site of ρ1 GABA<sub>C</sub> Receptors via Site Mutation and Partial Agonism.
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- PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0156618
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- Publication type:
- Article
2'-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors.
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- 2012
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- Publication type:
- journal article
Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors.
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- 2012
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- Publication type:
- journal article
2′-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA<sub>A</sub> receptors.
- Published in:
- British Journal of Pharmacology, 2012, v. 165, n. 4, p. 880, doi. 10.1111/j.1476-5381.2011.01604.x
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- Publication type:
- Article
Flavan-3-ol esters: new agents for exploring modulatory sites on GABA<sub>A</sub> receptors.
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- British Journal of Pharmacology, 2012, v. 165, n. 4, p. 965, doi. 10.1111/j.1476-5381.2011.01615.x
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- Publication type:
- Article
Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q.
- Published in:
- 2011
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- Publication type:
- journal article
Flavonoid modulation of GABA(A) receptors.
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- 2011
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- Publication type:
- journal article
GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn.
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- Evidence-based Complementary & Alternative Medicine (eCAM), 2016, v. 2016, p. 1, doi. 10.1155/2016/1215393
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- Publication type:
- Article
Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders.
- Published in:
- Molecules, 2019, v. 24, n. 3, p. 446, doi. 10.3390/molecules24030446
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- Publication type:
- Article
Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABA<sub>A</sub> Receptors.
- Published in:
- ChemMedChem, 2011, v. 6, n. 8, p. 1340, doi. 10.1002/cmdc.201100120
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- Article
Cover Picture: Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABA<sub>A</sub> Receptors (ChemMedChem 8/2011).
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- ChemMedChem, 2011, v. 6, n. 8, p. 1317, doi. 10.1002/cmdc.201190032
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- Publication type:
- Article
The β-amyloid protein of Alzheimer’s disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor.
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- Journal of Neurochemistry, 2007, v. 101, n. 6, p. 1527, doi. 10.1111/j.1471-4159.2006.04444.x
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- Article
(+)- and (-)-cis-2-Aminomethylcyclopropanecarboxylic Acids Show Opposite Pharmacology at Recombinant ρ[sub1] and ρ[sub2] GABA[subC] Receptors.
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- Journal of Neurochemistry, 2000, v. 75, n. 6, p. 2602, doi. 10.1046/j.1471-4159.2000.0752602.x
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- Publication type:
- Article
Stimulation of [<sup>3</sup>H]GABA and β-[<sup>3</sup>H]Alanine Release from Rat Brain Slices by cis-4-Aminocrotonic Acid.
- Published in:
- Journal of Neurochemistry, 1997, v. 68, n. 2, p. 786, doi. 10.1046/j.1471-4159.1997.68020786.x
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- Article
Medicinal chemistry and molecular pharmacology of GABA receptors and glutamate transporters-Complementary structure-activity relationships.
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- Drug Development Research, 1999, v. 46, n. 3/4, p. 255, doi. 10.1002/(SICI)1098-2299(199903/04)46:3/4<255::AID-DDR10>3.0.CO;2-S
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- Publication type:
- Article