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Common genetic variation within miR-146a predicts disease onset and relapse in multiple sclerosis.
Published in:
2018
By:
- Zhou, Yuan;
- Chen, Ming;
- Simpson, Steve;
- Lucas, Robyn M.;
- Charlesworth, Jac C.;
- Blackburn, Nicholas;
- van der Mei, Ingrid;
- Ponsonby, Anne-Louise;
- Ausimmune/AUSLONG investigators group;
- Taylor, Bruce V;
- Simpson, Steve Jr
Publication type:
journal article
Confirmation of the Adult-Onset Primary Open Angle Glaucoma Locus GLC1B at 2cen-q13 in an Australian Family.
Published in:
Ophthalmologica, 2006, v. 220, n. 1, p. 23, doi. 10.1159/000089271
By:
- Charlesworth, Jac C.;
- Stankovich, James M.;
- Mackey, David A.;
- Craig, Jamie E.;
- Haybittel, Michael;
- Westmore, Rodney N.;
- Sale, Michèle M.
Publication type:
Article
Comparison of pre-processing methodologies for Illumina 450k methylation array data in familial analyses.
Published in:
Clinical Epigenetics, 2016, v. 8, p. 1, doi. 10.1186/s13148-016-0241-2
By:
- Cazaly, Emma;
- Thomson, Russell;
- Marthick, James R.;
- Holloway, Adele F.;
- Charlesworth, Jac;
- Dickinson, Joanne L.
Publication type:
Article
Novel plasma and brain proteins that are implicated in multiple sclerosis.
Published in:
2023
By:
- Lin, Xin;
- Yang, Yuanhao;
- Gresle, Melissa;
- Cuellar-Partida, Gabriel;
- Han, Xikun;
- Stankovich, Jim;
- Group, AusLong;
- Simpson-Yap, Steve;
- Fuh-Ngwa, Valery;
- Charlesworth, Jac;
- Burdon, Kathryn P;
- Butzkueven, Helmut;
- Taylor, Bruce V;
- Zhou, Yuan;
- AusLong/Ausimmune Investigators Group Steve Simpson-Yap
Publication type:
journal article
The voltage‐gated calcium channel CaV1.2 promotes adult oligodendrocyte progenitor cell survival in the mouse corpus callosum but not motor cortex.
Published in:
Glia, 2020, v. 68, n. 2, p. 376, doi. 10.1002/glia.23723
By:
- Pitman, Kimberley A.;
- Ricci, Raphael;
- Gasperini, Robert;
- Beasley, Shannon;
- Pavez, Macarena;
- Charlesworth, Jac;
- Foa, Lisa;
- Young, Kaylene M.
Publication type:
Article
Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-23685-w
By:
- Fuh-Ngwa, Valery;
- Zhou, Yuan;
- Melton, Phillip E.;
- van der Mei, Ingrid;
- Charlesworth, Jac C.;
- Lin, Xin;
- Zarghami, Amin;
- Broadley, Simon A.;
- Ponsonby, Anne-Louise;
- Simpson-Yap, Steve;
- Lechner-Scott, Jeannette;
- Taylor, Bruce V.
Publication type:
Article
Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes.
Published in:
Nature Genetics, 2007, v. 39, n. 10, p. 1208, doi. 10.1038/ng2119
By:
- Göring, Harald H. H.;
- Curran, Joanne E.;
- Johnson, Matthew P.;
- Dyer, Thomas D.;
- Charlesworth, Jac;
- Cole, Shelley A.;
- Jowett, Jeremy B. M.;
- Abraham, Lawrence J.;
- Rainwater, David L.;
- Comuzzie, Anthony G.;
- Mahaney, Michael C.;
- Almasy, Laura;
- MacCluer, Jean W.;
- Kissebah, Ahmed H;
- Collier, Gregory R.;
- Moses, Eric K.;
- Blangero, John
Publication type:
Article
Variation within MBP gene predicts disease course in multiple sclerosis.
Published in:
Brain & Behavior, 2017, v. 7, n. 4, p. n/a, doi. 10.1002/brb3.670
By:
- Zhou, Yuan;
- Simpson, Steve;
- Charlesworth, Jac C.;
- Mei, Ingrid;
- Lucas, Robyn M.;
- Ponsonby, Anne‐Louise;
- Taylor, Bruce V.
Publication type:
Article
Utilising multi-large omics data to elucidate biological mechanisms within multiple sclerosis genetic susceptibility loci.
Published in:
Multiple Sclerosis Journal, 2021, v. 27, n. 14, p. 2141, doi. 10.1177/13524585211004422
By:
- Zhou, Yuan;
- Cuellar-Partida, Gabriel;
- Simpson Yap, Steve;
- Lin, Xin;
- Claflin, Suzi;
- Burdon, Kathryn;
- Charlesworth, Jac;
- Taylor, Bruce
Publication type:
Article
Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis.
Published in:
Multiple Sclerosis Journal, 2016, v. 22, n. 13, p. 1655, doi. 10.1177/1352458515626598
By:
- Zhou, Yuan;
- Zhu, Gu;
- Charlesworth, Jac C.;
- Simpson, Steve;
- Rubicz, Rohina;
- Göring, Harald H. H.;
- Patsopoulos, Nikolaos A.;
- Laverty, Caroline;
- Wu, Feitong;
- Henders, Anjali;
- Ellis, Jonathan J.;
- van der Mei, Ingrid;
- Montgomery, Grant W.;
- Blangero, John;
- Curran, Joanne E.;
- Johnson, Matthew P.;
- Martin, Nicholas G.;
- Nyholt, Dale R.;
- Taylor, Bruce V.
Publication type:
Article
Association between multiple sclerosis risk-associated SNPs and relapse and disability – a prospective cohort study.
Published in:
Multiple Sclerosis Journal, 2014, v. 20, n. 3, p. 313, doi. 10.1177/1352458513496882
By:
- Lin, Rui;
- Taylor, Bruce V;
- Simpson, Steve;
- Charlesworth, Jac;
- Ponsonby, Anne-Louise;
- Pittas, Fotini;
- Dwyer, Terry;
- van der Mei, Ingrid
Publication type:
Article
The potential role of epigenetic modifications in the heritability of multiple sclerosis.
Published in:
Multiple Sclerosis Journal, 2014, v. 20, n. 2, p. 135, doi. 10.1177/1352458514520911
By:
- Zhou, Yuan;
- Simpson, Steve;
- Holloway, Adele F;
- Charlesworth, Jac;
- van der Mei, Ingrid;
- Taylor, Bruce V
Publication type:
Article
Genetic Effects on DNA Methylation and Its Potential Relevance for Obesity in Mexican Americans.
Published in:
PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073950
By:
- Carless, Melanie A.;
- Kulkarni, Hemant;
- Kos, Mark Z.;
- Charlesworth, Jac;
- Peralta, Juan M.;
- Göring, Harald H. H.;
- Curran, Joanne E.;
- Almasy, Laura;
- Dyer, Thomas D.;
- Comuzzie, Anthony G.;
- Mahaney, Michael C.;
- Blangero, John
Publication type:
Article
Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0056379
By:
- Lin, Rui;
- Charlesworth, Jac;
- Stankovich, Jim;
- Perreau, Victoria M.;
- Brown, Matthew A.;
- Taylor, Bruce V.
Publication type:
Article
An X Chromosome Association Scan of the Norfolk Island Genetic Isolate Provides Evidence for a Novel Migraine Susceptibility Locus at Xq12.
Published in:
PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037903
By:
- Maher, Bridget H.;
- Lea, Rod A.;
- Benton, Miles;
- Cox, Hannah C.;
- Bellis, Claire;
- Carless, Melanie;
- Dyer, Thomas D.;
- Curran, Joanne;
- Charlesworth, Jac C.;
- Buring, Julie E.;
- Kurth, Tobias;
- Chasman, Daniel I.;
- Ridker, Paul M.;
- Schürks, Markus;
- Blangero, John;
- Griffiths, Lyn R.
Publication type:
Article
A Polymorphism in the HLA-DPB1 Gene Is Associated with Susceptibility to Multiple Sclerosis.
Published in:
PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013454
By:
- Field, Judith;
- Browning, Sharon R.;
- Laura J. Johnson;
- Danoy, Patrick;
- Varney, Michael D.;
- Tait, Brian D.;
- Gandhi, Kaushal S.;
- Charlesworth, Jac C.;
- Heard, Robert N.;
- Stewart, Graeme J.;
- Kilpatrick, Trevor J.;
- Foote, Simon J.;
- Bahlo, Melanie;
- Butzkueven, Helmut;
- Wiley, James;
- Booth, David R.;
- Taylor, Bruce V.;
- Brown, Matthew A.;
- Rubio, Justin P.;
- Stankovich, Jim
Publication type:
Article
Apparent autosomal dominant keratoconus in a large Australian pedigree accounted for by digenic inheritance of two novel loci.
Published in:
Human Genetics, 2008, v. 124, n. 4, p. 379, doi. 10.1007/s00439-008-0555-z
By:
- Burdon, Kathryn P.;
- Coster, Douglas J.;
- Charlesworth, Jac C.;
- Mills, Richard A.;
- Laurie, Kate J.;
- Giunta, Cecilia;
- Hewitt, Alex W.;
- Latimer, Paul;
- Craig, Jamie E.
Publication type:
Article
Association of Genetic Variation With Keratoconus.
Published in:
2020
By:
- McComish, Bennet J.;
- Sahebjada, Srujana;
- Bykhovskaya, Yelena;
- Willoughby, Colin E.;
- Richardson, Andrea J.;
- Tenen, Abi;
- Charlesworth, Jac C.;
- MacGregor, Stuart;
- Mitchell, Paul;
- Lucas, Sionne E. M.;
- Mills, Richard A.;
- Mackey, David A.;
- Li, Xiaohui;
- Wang, Jie Jin;
- Jensen, Richard A.;
- Rotter, Jerome I.;
- Taylor, Kent D.;
- Hewitt, Alex W.;
- Rabinowitz, Yaron S.;
- Baird, Paul N.
Publication type:
journal article
An Immunochip based interrogation of scleroderma susceptibility variants identifies a novel association at DNASE1L3.
Published in:
Arthritis Research & Therapy, 2014, v. 16, n. 5, p. 1, doi. 10.1186/s13075-014-0438-8
By:
- Zochling, Jane;
- Newell, Felicity;
- Charlesworth, Jac C.;
- Leo, Paul;
- Stankovich, Jim;
- Cortes, Adrian;
- Yuan Zhou;
- Stevens, Wendy;
- Sahhar, Joanne;
- Roddy, Janet;
- Nash, Peter;
- Tymms, Kathleen;
- Rischmueller, Maureen;
- Lester, Sue;
- Proudman, Susanna;
- Brown, Matthew A.
Publication type:
Article
Genome-wide linkage scan for loci influencing plasma triglyceride levels.
Published in:
BMC Proceedings, 2018, v. 12, n. 9, p. N.PAG, doi. 10.1186/s12919-018-0137-6
By:
- Peralta, Juan M.;
- Blackburn, Nicholas B.;
- Porto, Arthur;
- Blangero, John;
- Charlesworth, Jac
Publication type:
Article
Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes.
Published in:
BMC Medical Genomics, 2010, v. 3, p. 29, doi. 10.1186/1755-8794-3-29
By:
- Charlesworth, Jac C.;
- Curran, Joanne E.;
- Johnson, Matthew P.;
- Göring, Harald H. H.;
- Dyer, Thomas D.;
- Diego, Vincent P.;
- Kent, Jr, Jack W.;
- Mahaney, Michael C.;
- Almasy, Laura;
- MacCluer, Jean W.;
- Moses, Eric K.;
- Blangero, John
Publication type:
Article
Developing a clinical-environmental-genotypic prognostic index for relapsing-onset multiple sclerosis and clinically isolated syndrome.
Published in:
Brain Communications, 2021, v. 3, n. 4, p. 1, doi. 10.1093/braincomms/fcab288
By:
- Fuh-Ngwa, Valery;
- Yuan Zhou;
- Charlesworth, Jac C.;
- Ponsonby, Anne-Louise;
- Simpson-Yap, Steve;
- Lechner-Scott, Jeannette;
- Taylor, Bruce V.
Publication type:
Article
Genetic Determinants of Epigenetic Patterns: Providing Insight into Disease.
Published in:
Molecular Medicine, 2015, v. 21, n. 1, p. 400, doi. 10.2119/molmed.2015.00001
By:
- Cazaly, Emma;
- Charlesworth, Jac;
- Dickinson, Joanne L.;
- Holloway, Adele F.
Publication type:
Article
Genetic Analysis Workshop 17 mini-exome simulation.
Published in:
BMC Proceedings, 2011, v. 5, n. Suppl 9, p. 1, doi. 10.1186/1753-6561-5-S9-S2
By:
- Almasy, Laura;
- Dyer, Thomas D.;
- Peralta, Juan Manuel;
- Kent,Jr., Jack W.;
- Charlesworth, Jac C.;
- Curran, Joanne E.;
- Blangero, John
Publication type:
Article
Toward the identification of causal genes in complex diseases: a gene-centric joint test of significance combining genomic and transcriptomic data.
Published in:
BMC Proceedings, 2009, v. 3, p. 1, doi. 10.1186/1753-6561-3-S7-S92
By:
- Charlesworth, Jac C.;
- Peralta, Juan M.;
- Drigalenko, Eugene;
- Göring, Harald H. H.;
- Almasy, Laura;
- Dyer, Thomas D.;
- Blangero, John
Publication type:
Article
The Varied Mechanisms of Vitamin D in the Onset and Clinical Course of MS: Potential Roles in Modulating Other Etiological Pathways.
Published in:
Current Medical Literature: Neurology, 2011, v. 27, n. 1, p. 1
By:
- Simpson Jr., Steve;
- Greenhill, Kate;
- Van der Mei, Ingrid;
- Stankovich, Jim;
- Charlesworth, Jac;
- Taylor, Bruce V.
Publication type:
Article
Multiple Sclerosis Polygenic Risk Is Not Enriched in Three Multicase Families in Comparison to Population-Based Cases.
Published in:
Human Mutation, 2024, v. 2024, p. 1, doi. 10.1155/2024/9268911
By:
- Ming Chen;
- Motyer, Allan;
- Taylor, Bruce V.;
- McComish, Bennet J.;
- Burdon, Kathryn P.;
- Charlesworth, Jac C.;
- Blackburn, Nicholas B.
Publication type:
Article
Genetic determinants of mitochondrial content.
Published in:
Human Molecular Genetics, 2007, v. 16, n. 12, p. 1504, doi. 10.1093/hmg/ddm101
By:
- Curran, Joanne E.;
- Johnson, Matthew P.;
- Dyer, Thomas D.;
- Göring, Harald H.H.;
- Kent, Jack W.;
- Charlesworth, Jac C.;
- Borg, Anthony J.;
- Jowett, Jeremy B.M.;
- Cole, Shelley A.;
- MacCluer, Jean W.;
- Kissebah, Ahmed H.;
- Moses, Eric K.;
- Blangero, John
Publication type:
Article
Rare, potentially pathogenic variants in 21 keratoconus candidate genes are not enriched in cases in a large Australian cohort of European descent.
Published in:
PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199178
By:
- Lucas, Sionne E. M.;
- Charlesworth, Jac C.;
- Burdon, Kathryn P.;
- Blackburn, Nicholas B.;
- Zhou, Tiger;
- Mills, Richard A.;
- Souzeau, Emmanuelle;
- Ridge, Bronwyn;
- Craig, Jamie E.;
- Ellis, Jonathan;
- Leo, Paul;
- Lindsay, Richard
Publication type:
Article
Hepatic Gene Networks in Morbidly Obese Patients With Nonalcoholic Fatty Liver Disease.
Published in:
Obesity Surgery, 2010, v. 20, n. 12, p. 1698, doi. 10.1007/s11695-010-0171-6
By:
- Gawrieh, Samer;
- Baye, Tesfaye M.;
- Carless, Melanie;
- Wallace, James;
- Komorowski, Richard;
- Kleiner, David E.;
- Andris, Deborah;
- Makladi, Bassem;
- Cole, Regina;
- Charlton, Michael;
- Curran, Joanne;
- Dyer, Thomas D.;
- Charlesworth, Jac;
- Wilke, Russell;
- Blangero, John;
- Kissebah, Ahmed H.;
- Olivier, Michael
Publication type:
Article
A genome-wide analysis of 'Bounty' descendants implicates several novel variants in migraine susceptibility.
Published in:
Neurogenetics, 2012, v. 13, n. 3, p. 261, doi. 10.1007/s10048-012-0325-x
By:
- Cox, Hannah;
- Lea, Rod;
- Bellis, Claire;
- Carless, Melanie;
- Dyer, Thomas;
- Curran, Joanne;
- Charlesworth, Jac;
- Macgregor, Stuart;
- Nyholt, Dale;
- Chasman, Daniel;
- Ridker, Paul;
- Schürks, Markus;
- Blangero, John;
- Griffiths, Lyn
Publication type:
Article
Genome-Wide Genetic and Transcriptomic Investigation of Variation in Antibody Response to Dietary Antigens.
Published in:
Genetic Epidemiology, 2014, v. 38, n. 5, p. 439, doi. 10.1002/gepi.21817
By:
- Rubicz, Rohina;
- Yolken, Robert;
- Alaedini, Armin;
- Drigalenko, Eugene;
- Charlesworth, Jac C.;
- Carless, Melanie A.;
- Severance, Emily G.;
- Krivogorsky, Bogdana;
- Dyer, Thomas D.;
- Kent, Jack W.;
- Curran, Joanne E.;
- Johnson, Matthew P.;
- Cole, Shelley A.;
- Almasy, Laura;
- Moses, Eric K.;
- Blangero, John;
- Göring, Harald H. H.
Publication type:
Article
Principal Component and Linkage Analysis of Cardiovascular Risk Traits in the Norfolk Isolate.
Published in:
Human Heredity, 2009, v. 68, n. 1, p. 55, doi. 10.1159/000210449
By:
- Cox, Hannah C.;
- Bellis, Claire;
- Lea, Rod A.;
- Quinlan, Sharon;
- Hughes, Roger;
- Dyer, Thomas;
- Charlesworth, Jac;
- Blangero, John;
- Griffiths, Lyn R.
Publication type:
Article
The association between disability progression, relapses, and treatment in early relapse onset MS: an observational, multi-centre, longitudinal cohort study.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38415-z
By:
- Fuh-Ngwa, Valery;
- Charlesworth, Jac C.;
- Zhou, Yuan;
- van der Mei, Ingrid;
- Melton, Phillip E.;
- Broadley, Simon A.;
- Ponsonby, Anne-Louise;
- Simpson-Yap, Steve;
- Lechner-Scott, Jeannette;
- Taylor, Bruce V.
Publication type:
Article
Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic.
Published in:
Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0475-4
By:
- Nicol, Dianne;
- Eckstein, Lisa;
- Morrison, Michael;
- Sherkow, Jacob S.;
- Otlowski, Margaret;
- Whitton, Tess;
- Bubela, Tania;
- Burdon, Kathryn P.;
- Chalmers, Don;
- Chan, Sarah;
- Charlesworth, Jac;
- Critchley, Christine;
- Crossley, Merlin;
- de Lacey, Sheryl;
- Dickinson, Joanne L.;
- Hewitt, Alex W.;
- Kamens, Joanne;
- Kazuto Kato;
- Kleiderman, Erika;
- Satoshi Kodama
Publication type:
Article
A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study.
Published in:
Oncology Reports, 2015, v. 47, n. 1, p. 25, doi. 10.3892/or.2014.3568
By:
- BLACKBURN, NICHOLAS B.;
- CHARLESWORTH, JAC C.;
- MARTHICK, JAMES R.;
- TEGG, ELIZABETH M.;
- MARSDEN, KATHERINE A.;
- SRIKANTH, VELANDAI;
- BLANGERO, JOHN;
- LOWENTHAL, RAY M.;
- FOOTE, SIMON J.;
- DICKINSON, JOANNE L.
Publication type:
Article

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