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Enhancing natriuretic peptide bioactivity prevents bleomycin-induced pulmonary fibrosis.
Published in:
2011
By:
- Baliga, Reshma S.;
- Trinder, Sarah L.;
- Scotton, Christopher J.;
- Chambers, Rachel C.;
- MacAllister, Raymond J.;
- Hobbs, Adrian J.
Publication type:
Abstract
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.
Published in:
2009
By:
- Scotton, Chris J.;
- Krupiczojc, Malvina A.;
- Königshoff, Melanie;
- Mercer, Paul F.;
- Gary Lee, Y. C.;
- Kaminski, Naftali;
- Morser, John;
- Post, Joseph M.;
- Maher, Toby M.;
- Nicholson, Andrew G.;
- Moffatt, James D.;
- Laurent, Geoffrey J.;
- Derian, Claudia K.;
- Eickelberg, Oliver;
- Chambers, Rachel C.;
- Königshoff, Melanie;
- Lee, Y C Gary
Publication type:
journal article
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.
Published in:
2006
By:
- Jenkins, R. Gisli;
- Xiao Su;
- Su, George;
- Scotton, Christopher J.;
- Camerer, Eric;
- Laurent, Geoffrey J.;
- Davis, George E.;
- Chambers, Rachel C.;
- Matthay, Michael A.;
- Sheppard, Dean;
- Su, Xiao
Publication type:
journal article
mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1–induced collagen biosynthesis.
Published in:
Science Signaling, 2019, v. 12, n. 582, p. N.PAG, doi. 10.1126/scisignal.aav3048
By:
- Selvarajah, Brintha;
- Azuelos, Ilan;
- Platé, Manuela;
- Guillotin, Delphine;
- Forty, Ellen J.;
- Contento, Greg;
- Woodcock, Hannah V.;
- Redding, Matthew;
- Taylor, Adam;
- Brunori, Gino;
- Durrenberger, Pascal F.;
- Ronzoni, Riccardo;
- Blanchard, Andy D.;
- Mercer, Paul F.;
- Anastasiou, Dimitrios;
- Chambers, Rachel C.
Publication type:
Article
Signaling Pathways Involved in Proteinase-Activated Receptor1-Induced Proinflammatory and Profibrotic Mediator Release Following Lung Injury.
Published in:
Annals of the New York Academy of Sciences, 2007, v. 1096, p. 86, doi. 10.1196/annals.1397.073
By:
- MERCER, PAUL F.;
- DENG, XIAOLING;
- CHAMBERS, RACHEL C.
Publication type:
Article
Role of Serine Proteases in the Regulation of Interleukin-877 during the Development of Bronchopulmonary Dysplasia in Preterm Ventilated Infants.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114524
By:
- Chakraborty, Mallinath;
- McGreal, Eamon P.;
- Williams, Andrew;
- Davies, Philip L.;
- Powell, Wendy;
- Abdulla, Salima;
- Voitenok, Nikolai N.;
- Hogwood, John;
- Gray, Elaine;
- Spiller, Brad;
- Chambers, Rachel C.;
- Kotecha, Sailesh
Publication type:
Article
Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086241
By:
- Kallis, Yiannis N.;
- Scotton, Christopher J.;
- MacKinnon, Alison C.;
- Goldin, Robert D.;
- Wright, Nicholas A.;
- Iredale, John P.;
- Chambers, Rachel C.;
- Forbes, Stuart J.
Publication type:
Article
Residual Lung Abnormalities Following COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID Study.
Published in:
2023
By:
- Stewart, Iain;
- Jacob, Joseph;
- George, Peter M.;
- Molyneaux, Philip L.;
- Porter, Joanna C.;
- Allen, Richard J.;
- Aslani, Shahab;
- Baillie, J. Kenneth;
- Barratt, Shaney L.;
- Beirne, Paul;
- Bianchi, Stephen M.;
- Blaikley, John F.;
- Chalmers, James D.;
- Chambers, Rachel C.;
- Chadhuri, Nazia;
- Coleman, Christopher;
- Collier, Guilhem;
- Denneny, Emma K.;
- Docherty, Annemarie;
- Elneima, Omer
Publication type:
journal article
BARD1 mediates TGF-β signaling in pulmonary fibrosis.
Published in:
2015
By:
- André, Pierre-Alain;
- Prêle, Cecilia M.;
- Vierkotten, Sarah;
- Carnesecchi, Stéphanie;
- Donati, Yves;
- Chambers, Rachel C.;
- Pache, Jean-Claude;
- Crestani, Bruno;
- Barazzone-Argiroffo, Constance;
- Königshoff, Melanie;
- Laurent, Geoffrey J.;
- Irminger-Finger, Irmgard
Publication type:
journal article
Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch
Published in:
Cardiovascular Research, 2006, v. 71, n. 3, p. 548, doi. 10.1016/j.cardiores.2006.03.022
By:
- Ku, Ching-Hsin;
- Johnson, Philip H.;
- Batten, Puspa;
- Sarathchandra, Padmini;
- Chambers, Rachel C.;
- Taylor, Patricia M.;
- Yacoub, Magdi H.;
- Chester, Adrian H.
Publication type:
Article
An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 5, p. 667, doi. 10.1165/rcmb.2017-0096ST
By:
- Jenkins, R. Gisli;
- Moore, Bethany B.;
- Chambers, Rachel C.;
- Eickelberg, Oliver;
- Königshoff, Melanie;
- Kolb, Martin;
- Laurent, Geoffrey J.;
- Nanthakumar, Carmel B.;
- Olman, Mitchell A.;
- Pardo, Annie;
- Selman, Moises;
- Sheppard, Dean;
- Sime, Patricia J.;
- Tager, Andrew M.;
- Tatler, Amanda L.;
- Thannickal, Victor J.;
- White, Eric S.
Publication type:
Article
Proteinase-Activated Receptor-1, CCL2, and CCL7 Regulate Acute Neutrophilic Lung Inflammation.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 1, p. 144, doi. 10.1165/rcmb.2013-0142OC
By:
- Mercer, Paul F.;
- Williams, Andrew E.;
- Scotton, Christopher J.;
- José, Ricardo J.;
- Sulikowski, Michal;
- Moffatt, James D.;
- Murray, Lynne A.;
- Chambers, Rachel C.
Publication type:
Article
Characterization of a New Mouse Model of Empyema and the Mechanisms of Pleural Invasion by Streptococcus pneumoniae.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2012, v. 46, n. 2, p. 180, doi. 10.1165/rcmb.2011-0182OC
By:
- Wilkosz, Sylwia;
- Edwards, Lindsey A.;
- Bielsa, Silvia;
- Hyams, Catherine;
- Taylor, Abigail;
- Davies, Robert J. O.;
- Laurent, Geoffrey J.;
- Chambers, Rachel C.;
- Brown, Jeremy S.;
- Gary Lee, Y. C.
Publication type:
Article
Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2009, v. 41, n. 6, p. 680, doi. 10.1165/rcmb.2007-0386OC
By:
- Atzori, Luigi;
- Lucattelli, Monica;
- Scotton, Chris J.;
- Laurent, Geoffrey J.;
- Bartalesi, Barbara;
- Cunto, Giovanna De;
- Lunghi, Benedetta;
- Chambers, Rachel C.;
- Lungarella, Giuseppe
Publication type:
Article
Innate Immunity in Lung Fibrosis: A Therapeutic Role for Surfactant Protein D?
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 5, p. 471, doi. 10.1164/rccm.201112-2193ED
By:
- SCOTTON, CHRIS J.;
- CHAMBERS, RACHEL C.
Publication type:
Article
Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis.
Published in:
2010
By:
- Maher TM;
- Evans IC;
- Bottoms SE;
- Mercer PF;
- Thorley AJ;
- Nicholson AG;
- Laurent GJ;
- Tetley TD;
- Chambers RC;
- McAnulty RJ;
- Maher, Toby M;
- Evans, Iona C;
- Bottoms, Stephen E;
- Mercer, Paul F;
- Thorley, Andrew J;
- Nicholson, Andrew G;
- Laurent, Geoffrey J;
- Tetley, Teresa D;
- Chambers, Rachel C;
- McAnulty, Robin J
Publication type:
journal article
Fibrometabolism—An emerging therapeutic frontier in pulmonary fibrosis.
Published in:
Science Signaling, 2021, v. 14, n. 697, p. 1, doi. 10.1126/scisignal.aay1027
By:
- Selvarajah, Brintha;
- Azuelos, Ilan;
- Anastasiou, Dimitrios;
- Chambers, Rachel C.
Publication type:
Article
PAR-1-dependent and PAR-independent pro-inflammatory signaling in human lung fibroblasts exposed to thrombin.
Published in:
Journal of Cellular Physiology, 2012, v. 227, n. 11, p. 3575, doi. 10.1002/jcp.24061
By:
- Ortiz-Stern, Alejandro;
- Deng, Xiaoling;
- Smoktunowicz, Natalia;
- Mercer, Paul F.;
- Chambers, Rachel C.
Publication type:
Article
Alpha-1-antitrypsin stimulates fibroblast proliferation and procollagen production and activates classical MAP kinase signalling pathways.
Published in:
Journal of Cellular Physiology, 2001, v. 186, n. 1, p. 73, doi. 10.1002/1097-4652(200101)186:1<73::AID-JCP1002>3.0.CO;2-Q
By:
- Dabbagh, Karim;
- Laurent, Geoffrey J.;
- Shock, Anthony;
- Leoni, Patricia;
- Papakrivopoulou, Jenny;
- Chambers, Rachel C.
Publication type:
Article
Role of a functional polymorphism in the F2R gene promoter in sarcoidosis.
Published in:
Respirology, 2015, v. 20, n. 8, p. 1285, doi. 10.1111/resp.12608
By:
- Platé, Manuela;
- Lawson, Phillippa J.;
- Hill, Michael R.;
- Marshall, Richard P.;
- Booth, Helen L.;
- Kumari, Meena;
- Laurent, Geoffrey J.;
- Hurst, John R.;
- Chambers, Rachel C.
Publication type:
Article
Novel therapeutic approaches for pulmonary fibrosis.
Published in:
British Journal of Pharmacology, 2011, v. 163, n. 1, p. 141, doi. 10.1111/j.1476-5381.2011.01247.x
By:
- Datta, Arnab;
- Scotton, Chris J;
- Chambers, Rachel C
Publication type:
Article
A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01886-6
By:
- Johnston, Chris J. C.;
- Smyth, Danielle J.;
- Kodali, Ravindra B.;
- White, Madeleine P. J.;
- Harcus, Yvonne;
- Filbey, Kara J.;
- Hewitson, James P.;
- Hinck, Cynthia S.;
- Ivens, Alasdair;
- Kemter, Andrea M.;
- Kildemoes, Anna O.;
- Le Bihan, Thierry;
- Soares, Dinesh C.;
- Anderton, Stephen M.;
- Brenn, Thomas;
- Wigmore, Stephen J.;
- Woodcock, Hannah V.;
- Chambers, Rachel C.;
- Hinck, Andrew P.;
- McSorley, Henry J.
Publication type:
Article
Mechanisms of Alveolar Epithelial Injury, Repair, and Fibrosis.
Published in:
Annals of the American Thoracic Society, 2015, v. 12, p. S16, doi. 10.1513/AnnalsATS.201410-448MG
By:
- Chambers, Rachel C.;
- Mercer, Paul F.
Publication type:
Article
Single-cell analysis of bronchoalveolar cells in inflammatory and fibrotic post-COVID lung disease.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1372658
By:
- Mehta, Puja;
- Duque de Estrada, Blanca Sanz-Magallón;
- Denneny, Emma K.;
- Foster, Kane;
- Turner, Carolin T.;
- Mayer, Andreas;
- Milighetti, Martina;
- Platé, Manuela;
- Worlock, Kaylee B.;
- Masahiro Yoshida;
- Brown, Jeremy S.;
- Nikolić, Marko Z.;
- Chain, Benjamin M.;
- Noursadeghi, Mahdad;
- Chambers, Rachel C.;
- Porter, Joanna C.;
- Tomlinson, Gillian S.
Publication type:
Article
Proteinase-activated receptors and the pathophysiology of pulmonary fibrosis.
Published in:
Drug Development Research, 2003, v. 60, n. 1, p. 29, doi. 10.1002/ddr.10317
By:
- Rachel C. Chambers
Publication type:
Article
Altered Surfactant Homeostasis and Alveolar Epithelial Cell Stress in Amiodarone-Induced Lung Fibrosis.
Published in:
Toxicological Sciences, 2014, v. 142, n. 1, p. 285, doi. 10.1093/toxsci/kfu177
By:
- Mahavadi, Poornima;
- Henneke, Ingrid;
- Ruppert, Clemens;
- Knudsen, Lars;
- Venkatesan, Shalini;
- Liebisch, Gerhard;
- Chambers, Rachel C.;
- Ocha, Matthias;
- Schmitz, Gerd;
- Vancheri, Carlo;
- Seeger, Werner;
- Korfei, Martina;
- Guenther, Andreas
Publication type:
Article

Found: 26

Enhancing natriuretic peptide bioactivity prevents bleomycin-induced pulmonary fibrosis.

Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.

Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β<sub>1</sub>–induced collagen biosynthesis.

Signaling Pathways Involved in Proteinase-Activated Receptor<sub>1</sub>-Induced Proinflammatory and Profibrotic Mediator Release Following Lung Injury.

Role of Serine Proteases in the Regulation of Interleukin-8<sub>77</sub> during the Development of Bronchopulmonary Dysplasia in Preterm Ventilated Infants.

Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages.

Residual Lung Abnormalities Following COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID Study.

BARD1 mediates TGF-β signaling in pulmonary fibrosis.

Collagen synthesis by mesenchymal stem cells and aortic valve interstitial cells in response to mechanical stretch

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

Proteinase-Activated Receptor-1, CCL2, and CCL7 Regulate Acute Neutrophilic Lung Inflammation.

Characterization of a New Mouse Model of Empyema and the Mechanisms of Pleural Invasion by Streptococcus pneumoniae.

Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia.

Innate Immunity in Lung Fibrosis: A Therapeutic Role for Surfactant Protein D?

Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis.

Fibrometabolism—An emerging therapeutic frontier in pulmonary fibrosis.

PAR-1-dependent and PAR-independent pro-inflammatory signaling in human lung fibroblasts exposed to thrombin.

Alpha-1-antitrypsin stimulates fibroblast proliferation and procollagen production and activates classical MAP kinase signalling pathways.

Role of a functional polymorphism in the F2R gene promoter in sarcoidosis.

Novel therapeutic approaches for pulmonary fibrosis.

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

Mechanisms of Alveolar Epithelial Injury, Repair, and Fibrosis.

Single-cell analysis of bronchoalveolar cells in inflammatory and fibrotic post-COVID lung disease.

Proteinase-activated receptors and the pathophysiology of pulmonary fibrosis.

Altered Surfactant Homeostasis and Alveolar Epithelial Cell Stress in Amiodarone-Induced Lung Fibrosis.