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CD28/CTLA-4/B7 costimulatory pathway blockade affects regulatory T-cell function in autoimmunity.
Published in:
European Journal of Immunology, 2015, v. 45, n. 6, p. 1832, doi. 10.1002/eji.201445190
By:
- Vogel, Isabel;
- Kasran, Ahmad;
- Cremer, Jonathan;
- Kim, Yoo‐Jin;
- Boon, Louis;
- Van Gool, Stefaan W.;
- Ceuppens, Jan L.
Publication type:
Article
Foxp3+ regulatory T cells are activated in spite of B7-CD28 and CD40-CD40L blockade.
Published in:
European Journal of Immunology, 2013, v. 43, n. 4, p. 1013, doi. 10.1002/eji.201242737
By:
- Vogel, Isabel;
- Verbinnen, Bert;
- Maes, Wim;
- Boon, Louis;
- Van Gool, Stefaan W.;
- Ceuppens, Jan L.
Publication type:
Article
Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model.
Published in:
Frontiers in Immunology, 2022, v. 13, p. N.PAG, doi. 10.3389/fimmu.2022.849155
By:
- Jonckheere, Anne-Charlotte;
- Seys, Sven F.;
- Steelant, Brecht;
- Decaesteker, Tatjana;
- Dekoster, Kaat;
- Cremer, Jonathan;
- Dilissen, Ellen;
- Schols, Dominique;
- Iwakura, Yoichiro;
- Vande Velde, Greetje;
- Breynaert, Christine;
- Schrijvers, Rik;
- Vanoirbeek, Jeroen;
- Ceuppens, Jan L.;
- Dupont, Lieven J.;
- Bullens, Dominique M. A.
Publication type:
Article
Effects of co-stimulation by CD58 on human T cell cytokine production: a selective cytokine pattern with induction of high IL-10 production.
Published in:
International Immunology, 2001, v. 13, n. 2, p. 181, doi. 10.1093/intimm/13.2.181
By:
- Bullens, Dominique M. A.;
- Rafiq, Khadija;
- Charitidou, Lydia;
- Peng, Xiaohui;
- Kasran, Ahmad;
- Warmerdam, Petra A. M.;
- Van Gool, Stefaan W.;
- Ceuppens, Jan L.
Publication type:
Article
B7–CD28 interaction is a late acting co-stimulatory signal for human T cell responses.
Published in:
International Immunology, 1997, v. 9, n. 8, p. 1095, doi. 10.1093/intimm/9.8.1095
By:
- Yi-qun Zhang;
- Joost van Neerven, R. J.;
- Van Gool, Stefaan W.;
- Coorevits, Lieve;
- de Boer, Mark;
- Ceuppens, Jan L.
Publication type:
Article
Differential requirements for co-stimulatory signals from B7 family members by resting versus recently activated memory T cells towards soluble recall antigens.
Published in:
International Immunology, 1996, v. 8, n. 1, p. 37, doi. 10.1093/intimm/8.1.37
By:
- Yi-qun, Zhang;
- Neerven, R. J. Joost van;
- Kasran, Ahmad;
- Boer, Mark de;
- Ceuppens, Jan L.
Publication type:
Article
Identification of an enriched CD4.
Published in:
International Journal of Cancer, 1997, v. 71, n. 2, p. 178, doi. 10.1002/(SICI)1097-0215(19970410)71:2<178::AID-IJC9>3.0.CO;2-Y
By:
- Van den Hove, Ludwig E.;
- Van Gool, Stefaan W.;
- Van Poppel, Hein;
- Baert, Luc;
- Coorevits, Lieve;
- Van Damme, Boudewijn;
- Dal Cin, Paola;
- Van den Berghe, Herman;
- Ceuppens, Jan L.
Publication type:
Article
Unique Gene Expression and MR T2 Relaxometry Patterns Define Chronic Murine Dextran Sodium Sulphate Colitis as a Model for Connective Tissue Changes in Human Crohn’s Disease.
Published in:
PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068876
By:
- Breynaert, Christine;
- Dresselaers, Tom;
- Perrier, Clémentine;
- Arijs, Ingrid;
- Cremer, Jonathan;
- Van Lommel, Leentje;
- Van Steen, Kristel;
- Ferrante, Marc;
- Schuit, Frans;
- Vermeire, Séverine;
- Rutgeerts, Paul;
- Himmelreich, Uwe;
- Ceuppens, Jan L.;
- Geboes, Karel;
- Van Assche, Gert
Publication type:
Article
Sensitization to Inhaled Ryegrass Pollen by Collateral Priming in a Murine Model of Allergic Respiratory Disease.
Published in:
International Archives of Allergy & Immunology, 2010, v. 152, n. 3, p. 233, doi. 10.1159/000283031
By:
- Cadot, Pascal;
- Meyts, Isabelle;
- Vanoirbeek, Jeroen A.J.;
- Vanaudenaerde, Bart;
- Bullens, Dominique M. A.;
- Ceuppens, Jan L.
Publication type:
Article
Interleukin-17 Orchestrates the Granulocyte Influx into Airways after Allergen Inhalation in a Mouse Model of Allergic Asthma.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2003, v. 28, n. 1, p. 42, doi. 10.1165/rcmb.4832
By:
- Hellings, Peter W.;
- Kasran, Ahmad;
- Zhanju Liu;
- Vandekerckhove, Philippe;
- Wuyts, Anja;
- Overbergh, Lutgart;
- Mathieu, Chantal;
- Ceuppens, Jan L.
Publication type:
Article
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
Published in:
Respiratory Research, 2006, v. 7, p. 1, doi. 10.1186/1465-9921-7-135
By:
- Bullens, Dominique M. A.;
- Truyen, Els;
- Coteur, Liesbeth;
- Dilissen, Ellen;
- Hellings, Peter W.;
- Dupont, Lieven J.;
- Ceuppens, Jan L.
Publication type:
Article
Uptake and presentation of malignant glioma tumor cell lysates by monocyte-derived dendritic cells.
Published in:
Cancer Immunology, Immunotherapy, 2005, v. 54, n. 4, p. 372, doi. 10.1007/s00262-004-0615-8
By:
- de Vleeschouwer, Steven;
- Arredouani, Mohammed;
- Adé, Martine;
- Cadot, Pascal;
- Vermassen, Elke;
- Ceuppens, Jan. L.;
- van Gool, Stefaan W.
Publication type:
Article
Placental Growth Factor Contributes to Bronchial Neutrophilic Inflammation and Edema in Allergic Asthma.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2012, v. 46, n. 6, p. 781, doi. 10.1165/rcmb.2011-0152OC
By:
- Bobic, Sonja;
- Seys, Sven;
- De Vooght, Vanessa;
- Callebaut, Ina;
- Hox, Valerie;
- Dooms, Christophe;
- Vinckier, Stefan;
- Jonckx, Bart;
- Saint-Remy, Jean-Marie;
- Stassen, Jean-Marie;
- Bullens, Dominique M. A.;
- Ceuppens, Jan L.;
- Carmeliet, Peter;
- Hellings, Peter W.
Publication type:
Article
Selective Nasal Allergen Provocation Induces Substance P- Mediated Bronchial Hyperresponsiveness.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2011, v. 44, n. 4, p. 517, doi. 10.1165/rcmb.2009-0425OC
By:
- Hens, Greet;
- Raap, Ulrike;
- Vanoirbeek, Jeroen;
- Meyts, Isabelle;
- Callebaut, Ina;
- Verbinnen, Bert;
- Vanaudenaerde, Bart M.;
- Cadot, Pascal;
- Nemery, Benoit;
- Bullens, Dominique M. A.;
- Ceuppens, Jan L.;
- Hellings, Peter W.
Publication type:
Article
Cluster analysis of sputum cytokine-high profiles reveals diversity in T(h)2-high asthma patients.
Published in:
2017
By:
- Seys, Sven F.;
- Scheers, Hans;
- Van den Brande, Paul;
- Marijsse, Gudrun;
- Dilissen, Ellen;
- Van Den Bergh, Annelies;
- Goeminne, Pieter C.;
- Hellings, Peter W.;
- Ceuppens, Jan L.;
- Dupont, Lieven J.;
- Bullens, Dominique M. A.
Publication type:
journal article
Fibrogenesis in Chronic DSS Colitis is Not Influenced by Neutralisation of Regulatory T Cells, of Major T Helper Cytokines or Absence of IL-13.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46472-6
By:
- Creyns, Brecht;
- Cremer, Jonathan;
- Hoshino, Tomoaki;
- Geboes, Karel;
- de Hertogh, Gert;
- Ferrante, Marc;
- Vermeire, Séverine;
- Ceuppens, Jan L.;
- Van Assche, Gert;
- Breynaert, Christine
Publication type:
Article
Restoring airway epithelial barrier dysfunction: a new therapeutic challenge in allergic airway disease.
Published in:
Rhinology, 2016, v. 54, p. 195, doi. 10.4193/Rhino15.376
By:
- Steelant, Brecht;
- Seys, Sven F.;
- Boeckxstaens, Guy;
- Akdis, Cezmi A.;
- Ceuppens, Jan L.;
- Hellings, Peter W.
Publication type:
Article
Biological Therapy in Inflammatory Bowel Disease Patients Partly Restores Intestinal Innate Lymphoid Cell Subtype Equilibrium.
Published in:
Frontiers in Immunology, 2020, p. N.PAG, doi. 10.3389/fimmu.2020.01847
By:
- Creyns, Brecht;
- Jacobs, Inge;
- Verstockt, Bram;
- Cremer, Jonathan;
- Ballet, Vera;
- Vandecasteele, Roselien;
- Vanuytsel, Tim;
- Ferrante, Marc;
- Vermeire, Séverine;
- Van Assche, Gert;
- Ceuppens, Jan L.;
- Breynaert, Christine
Publication type:
Article
Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo.
Published in:
Immunology, 2005, v. 114, n. 2, p. 263, doi. 10.1111/j.1365-2567.2004.02071.x
By:
- Arredouani, Mohamed S.;
- Kasran, Ahmad;
- Vanoirbeek, Jeroen A.;
- Berger, Frank G.;
- Baumann, Heinz;
- Ceuppens, Jan L.
Publication type:
Article
Obese Individuals with Asthma Preferentially Have a High IL-5/IL-17A/IL-25 Sputum Inflammatory Pattern.
Published in:
2014
By:
- Marijsse, Gudrun S;
- Seys, Sven F;
- Schelpe, An-Sofie;
- Dilissen, Ellen;
- Goeminne, Pieter;
- Dupont, Lieven J;
- Ceuppens, Jan L;
- Bullens, Dominique M A
Publication type:
Journal Article
Obese Individuals with Asthma Preferentially Have a High IL-5/IL-17A/IL-25 Sputum Inflammatory Pattern.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 189, n. 10, p. 1284, doi. 10.1164/rccm.201311-2011le
By:
- Marijsse, Gudrun S.;
- Seys, Sven F.;
- Schelpe, An-Sofie;
- Dilissen, Ellen;
- Goeminne, Pieter;
- Dupont, Lieven J.;
- Ceuppens, Jan L.;
- Bullens, Dominique M. A.
Publication type:
Article
Crucial Role of Transient Receptor Potential Ankyrin 1 and Mast Cells in Induction of Nonallergic Airway Hyperreactivity in Mice.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 5, p. 486, doi. 10.1164/rccm.201208-1358OC
By:
- Hox, Valérie;
- Vanoirbeek, Jeroen A.;
- Alpizar, Yeranddy A.;
- Voedisch, Sabrina;
- Callebaut, Ina;
- Bobic, Sonja;
- Sharify, Ali;
- De Vooght, Vanessa;
- Van Gerven, Laura;
- Devos, Fien;
- Liston, Adrian;
- Voets, Thomas;
- Vennekens, Rudi;
- Bullens, Dominique M. A.;
- De Vries, Annick;
- Hoet, Peter;
- Braun, Armin;
- Ceuppens, Jan L.;
- Talavera, Karel;
- Nemery, Benoit
Publication type:
Article
Respiratory Response to Toluene Diisocyanate Depends on Prior Frequency and Concentration of Dermal Sensitization in Mice.
Published in:
Toxicological Sciences, 2004, v. 80, n. 2, p. 310, doi. 10.1093/toxsci/kfh155
By:
- Vanoirbeek, Jeroen A. J.;
- Tarkowski, Maciej;
- Ceuppens, Jan L.;
- Verbeken, Erik K.;
- Nemery, Benoit;
- Hoet, Peter H. M.
Publication type:
Article
Fibrogenesis in chronic murine colitis is independent of innate lymphoid cells.
Published in:
Immunity, Inflammation & Disease, 2020, v. 8, n. 3, p. 393, doi. 10.1002/iid3.321
By:
- Creyns, Brecht;
- Cremer, Jonathan;
- De Hertogh, Gert;
- Boon, Louis;
- Ferrante, Marc;
- Vermeire, Séverine;
- Van Assche, Gert;
- Ceuppens, Jan L.;
- Breynaert, Christine
Publication type:
Article
Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab.
Published in:
Immunology, 2013, v. 138, n. 1, p. 47, doi. 10.1111/imm.12014
By:
- Perrier, Clémentine;
- Arijs, Ingrid;
- Staelens, Dominiek;
- Breynaert, Christine;
- Cleynen, Isabelle;
- Covens, Kris;
- Ferrante, Marc;
- Assche, Gert;
- Vermeire, Séverine;
- Hertogh, Gert;
- Schuit, Frans;
- Rutgeerts, Paul;
- Ceuppens, Jan L.
Publication type:
Article
Nasal epithelial barrier dysfunction increases sensitization and mast cell degranulation in the absence of allergic inflammation.
Published in:
Allergy, 2020, v. 75, n. 5, p. 1155, doi. 10.1111/all.14132
By:
- Kortekaas Krohn, Inge;
- Seys, Sven F.;
- Lund, Gitte;
- Jonckheere, Anne‐Charlotte;
- Dierckx de Casterlé, Isabelle;
- Ceuppens, Jan L.;
- Steelant, Brecht;
- Hellings, Peter W.
Publication type:
Article
A new acute inflammatory syndrome related to the introduction of mycophenolate mofetil in patients with Wegener's granulomatosis.
Published in:
Nephrology Dialysis Transplantation, 2002, v. 17, n. 5, p. 923, doi. 10.1093/ndt/17.5.923
By:
- Maes, Bart;
- Oellerich, Michael;
- Ceuppens, Jan L.;
- Armstrong, Victor W.;
- Evenepoel, Pieter;
- Kuypers, Dirk;
- Messiaen, Thierry;
- Shipkova, Maria;
- Wieland, Eberhard;
- Vanrenterghem, Yves
Publication type:
Article
Mucosal IL13RA2 expression predicts nonresponse to anti‐TNF therapy in Crohn's disease.
Published in:
Alimentary Pharmacology & Therapeutics, 2019, v. 49, n. 5, p. 572, doi. 10.1111/apt.15126
By:
- Verstockt, Bram;
- Verstockt, Sare;
- Creyns, Brecht;
- Tops, Sophie;
- Van Assche, Gert;
- Gils, Ann;
- Ceuppens, Jan L.;
- Vermeire, Séverine;
- Ferrante, Marc;
- Breynaert, Christine
Publication type:
Article
Targeting of Costimulatory Molecules as a Therapeutic Approach in Inflammatory Bowel Disease.
Published in:
BioDrugs, 2003, v. 17, n. 6, p. 395, doi. 10.2165/00063030-200317060-00003
By:
- Maerten, Philippe;
- Zhanju Liu, Philippe;
- Ceuppens, Jan L.
Publication type:
Article
Haptoglobin deficiency facilitates the development of autoimmune inflammation.
Published in:
European Journal of Immunology, 2009, v. 39, n. 12, p. 3404, doi. 10.1002/eji.200939291
By:
- Galicia, Georgina;
- Maes, Wim;
- Verbinnen, Bert;
- Kasran, Ahmad;
- Bullens, Dominique;
- Arredouani, Mohamed;
- Ceuppens, Jan L.
Publication type:
Article
1α,25-Dihydroxyvitamin D.
Published in:
European Journal of Immunology, 2005, v. 35, n. 6, p. 1841, doi. 10.1002/eji.200425784
By:
- Jeurissen, Axel;
- Van Etten, Evelyne;
- Overbergh, Lut;
- Wuyts, Greet;
- Heremans, Hubertine;
- Matthys, Patrick;
- Ceuppens, Jan L.;
- Mathieu, Chantal;
- Bossuyt, Xavier
Publication type:
Article
The human antibody response to pneumococcal capsular polysaccharides is dependent on the CD40-CD40 ligand interaction.
Published in:
European Journal of Immunology, 2004, v. 34, n. 3, p. 850, doi. 10.1002/eji.200324381
By:
- Jeurissen, Axel;
- Wuyts, Greet;
- Kasran, Ahmad;
- Ramdien-Murli, Seema;
- Blanckaert, Norbert;
- Boon, Louis;
- Ceuppens, Jan L.;
- Bossuyt, Xavier
Publication type:
Article
Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice.
Published in:
European Journal of Immunology, 2002, v. 32, n. 2, p. 585, doi. 10.1002/1521-4141(200202)32:2<585::AID-IMMU585>3.0.CO;2-U
By:
- Hellings, Peter W.;
- Vandenberghe, Peter;
- Kasran, Ahmad;
- Coorevits, Lieve;
- Overbergh, Lutgart;
- Mathieu, Chantal;
- Ceuppens, Jan L.
Publication type:
Article
Role of interleukin-12 in the induction of mucosal inflammation and abrogation of regulatory T cell function in chronic experimental colitis.
Published in:
European Journal of Immunology, 2001, v. 31, n. 5, p. 1550, doi. 10.1002/1521-4141(200105)31:5<1550::AID-IMMU1550>3.0.CO;2-3
By:
- Liu, Zhanju;
- Geboes, Karel;
- Heremans, Hubertine;
- Overbergh, Lutgart;
- Mathieu, Chantal;
- Rutgeerts, Paul;
- Ceuppens, Jan L.
Publication type:
Article
Blocking CD40 - CD154 and CD80/CD86 - CD28 interactions during primary allogeneic stimulation results in T cell anergy and high IL-10 production.
Published in:
European Journal of Immunology, 1999, v. 29, n. 8, p. 2367, doi. 10.1002/(SICI)1521-4141(199908)29:08<2367::AID-IMMU2367>3.0.CO;2-3
By:
- Van Gool, Stefaan W.;
- Vermeiren, Jan;
- Rafiq, Khadija;
- Lorré, Katrien;
- de Boer, Mark;
- Ceuppens, Jan L.
Publication type:
Article
Cyclosporin A increases IFN-γ production by T cells when co-stimulated through CD28.
Published in:
European Journal of Immunology, 1998, v. 28, n. 5, p. 1481, doi. 10.1002/(SICI)1521-4141(199805)28:05<1481::AID-IMMU1481>3.0.CO;2-4
By:
- Rafiq, Khadija;
- Kasran, Ahmad;
- Peng, Xiaohui;
- Warmerdam, Petra A. M.;
- Coorevits, Lieve;
- Ceuppens, Jan L.;
- Van Gool, Stefaan W.
Publication type:
Article
Accessory signaling by CD40 for T cell activation: induction of Th1 and Th2 cytokines and synergy with interleukin-12 for interferon-γ production.
Published in:
European Journal of Immunology, 1996, v. 26, n. 7, p. 1621, doi. 10.1002/eji.1830260732
By:
- Peng, Xiaohui;
- Kasran, Ahmad;
- Warmerdam, Petra A. M.;
- De Boer, Mark;
- Ceuppens, Jan L.
Publication type:
Article
Ligation of B7 with CD28/CTLA-4 on T cells results in CD40 ligand expression, interleukin-4 secretion and efficient help for antibody production by B cells.
Published in:
European Journal of Immunology, 1993, v. 23, n. 12, p. 3120, doi. 10.1002/eji.1830231212
By:
- de Boer, Mark;
- Kasran, Ahmad;
- Kwekkeboom, Jaap;
- Walter, Hugo;
- Vandenberghe, Peter;
- Ceuppens, Jan L.
Publication type:
Article
Immobilized anti-CD5 together with prolonged activation of protein kinase C induce interleukin 2-dependent T cell growth: evidence for signal transduction through CD5.
Published in:
European Journal of Immunology, 1991, v. 21, n. 2, p. 251, doi. 10.1002/eji.1830210203
By:
- Vandenberghe, Peter;
- Ceuppens, Jan L.
Publication type:
Article
A bidirectional regulatory network involving IL 2 and IL 4 in the alternative CD2 pathway of T cell activation.
Published in:
European Journal of Immunology, 1990, v. 20, n. 7, p. 1569, doi. 10.1002/eji.1830200724
By:
- Lorré, Katrien;
- Van Damme, Jo;
- Ceuppens, Jan L.
Publication type:
Article
Tumor necrosis factor-α and interleukin 6 synergistically induce T cell growth.
Published in:
European Journal of Immunology, 1990, v. 20, n. 5, p. 1019, doi. 10.1002/eji.1830200511
By:
- Kuhweide, Rudolf;
- van Damme, Jo;
- Ceuppens, Jan L.
Publication type:
Article
Nasal allergen deposition leads to conjunctival mast cell degranulation in allergic rhinoconjunctivitis.
Published in:
American Journal of Rhinology & Allergy, 2014, v. 28, n. 4, p. 290, doi. 10.2500/ajra.2014.28.4052
By:
- Callebaut, Ina;
- De Vries, Annick;
- Steelant, Brecht;
- Hox, Valérie;
- Bobic, Sonja;
- Van Gerven, Laura;
- Ceuppens, Jan L.;
- Hellings, Peter W.
Publication type:
Article
Anti-tumor necrosis factor treatment restores the gut barrier in Crohn’s disease
Published in:
American Journal of Gastroenterology (Springer Nature), 2002, v. 97, n. 8, p. 2000, doi. 10.1111/j.1572-0241.2002.05914.x
By:
- Suenaert, Peter;
- Bulteel, Veerle;
- Lemmens, Liesbeth;
- Noman, Maja;
- Geypens, Benny;
- Assche, Gert Van;
- Geboes, Karel;
- Ceuppens, Jan L.;
- Rutgeerts, Paul
Publication type:
Article

Found: 43