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Characterization of the Blood–Brain Barrier Integrity and the Brain Transport of SN-38 in an Orthotopic Xenograft Rat Model of Diffuse Intrinsic Pontine Glioma.
Published in:
Pharmaceutics, 2020, v. 12, n. 5, p. 399, doi. 10.3390/pharmaceutics12050399
By:
- Chaves, Catarina;
- Declèves, Xavier;
- Taghi, Meryam;
- Menet, Marie-Claude;
- Lacombe, Joelle;
- Varlet, Pascale;
- Olaciregui, Nagore G.;
- Carcaboso, Angel M.;
- Cisternino, Salvatore
Publication type:
Article
Proteomics of Aqueous Humor as a Source of Disease Biomarkers in Retinoblastoma.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13458, doi. 10.3390/ijms232113458
By:
- Galardi, Angela;
- Stathopoulos, Christina;
- Colletti, Marta;
- Lavarello, Chiara;
- Russo, Ida;
- Cozza, Raffaele;
- Romanzo, Antonino;
- Carcaboso, Angel M.;
- Locatelli, Franco;
- Petretto, Andrea;
- Munier, Francis L.;
- Di Giannatale, Angela
Publication type:
Article
AC-265347 Inhibits Neuroblastoma Tumor Growth by Induction of Differentiation without Causing Hypocalcemia.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 8, p. 4323, doi. 10.3390/ijms23084323
By:
- Gonçalves-Alves, Eliana;
- Garcia, Marta;
- Rodríguez-Hernández, Carlos J.;
- Gómez-González, Soledad;
- Ecker, Rupert C.;
- Suñol, Mariona;
- Muñoz-Aznar, Oscar;
- Carcaboso, Angel M.;
- Mora, Jaume;
- Lavarino, Cinzia;
- Mateo-Lozano, Silvia
Publication type:
Article
Tridimensional Retinoblastoma Cultures as Vitreous Seeds Models for Live-Cell Imaging of Chemotherapy Penetration.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1077, doi. 10.3390/ijms20051077
By:
- Winter, Ursula;
- Aschero, Rosario;
- Fuentes, Federico;
- Buontempo, Fabian;
- Zugbi, Santiago;
- Sgroi, Mariana;
- Sampor, Claudia;
- Abramson, David H.;
- Carcaboso, Angel M.;
- Schaiquevich, Paula
Publication type:
Article
Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance.
Published in:
Fluids & Barriers of the CNS, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12987-020-00198-0
By:
- Deligne, Clémence;
- Hachani, Johan;
- Duban-Deweer, Sophie;
- Meignan, Samuel;
- Leblond, Pierre;
- Carcaboso, Angel M.;
- Sano, Yasuteru;
- Shimizu, Fumitaka;
- Kanda, Takashi;
- Gosselet, Fabien;
- Dehouck, Marie-Pierre;
- Mysiorek, Caroline
Publication type:
Article
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.
Published in:
Nature Genetics, 2014, v. 46, n. 5, p. 457, doi. 10.1038/ng.2925
By:
- Taylor, Kathryn R;
- Mackay, Alan;
- Truffaux, Nathalène;
- Butterfield, Yaron S;
- Morozova, Olena;
- Philippe, Cathy;
- Castel, David;
- Grasso, Catherine S;
- Vinci, Maria;
- Carvalho, Diana;
- Carcaboso, Angel M;
- de Torres, Carmen;
- Cruz, Ofelia;
- Mora, Jaume;
- Entz-Werle, Natacha;
- Ingram, Wendy J;
- Monje, Michelle;
- Hargrave, Darren;
- Bullock, Alex N;
- Puget, Stéphanie
Publication type:
Article
CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.
Published in:
2018
By:
- Stallard, Stefanie;
- Savelieff, Masha G.;
- Wierzbicki, Kyle;
- Mullan, Brendan;
- Miklja, Zachary;
- Bruzek, Amy;
- Garcia, Taylor;
- Siada, Ruby;
- Anderson, Bailey;
- Singer, Benjamin H.;
- Hashizume, Rintaro;
- Carcaboso, Angel M.;
- McMurray, Kaitlin Q.;
- Heth, Jason;
- Muraszko, Karin;
- Robertson, Patricia L.;
- Mody, Rajen;
- Venneti, Sriram;
- Garton, Hugh;
- Koschmann, Carl
Publication type:
Letter
Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours.
Published in:
Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0449-1
By:
- Haque, Farhana;
- Varlet, Pascale;
- Puntonet, Julien;
- Storer, Lisa;
- Bountali, Aikaterini;
- Rahman, Ruman;
- Grill, Jacques;
- Carcaboso, Angel M.;
- Jones, Chris;
- Layfield, Robert;
- Grundy, Richard G.
Publication type:
Article
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11732-6
By:
- Fons, Nathan R.;
- Sundaram, Ranjini K.;
- Breuer, Gregory A.;
- Peng, Sen;
- McLean, Ryan L.;
- Kalathil, Aravind N.;
- Schmidt, Mark S.;
- Carvalho, Diana M.;
- Mackay, Alan;
- Jones, Chris;
- Carcaboso, Ángel M.;
- Nazarian, Javad;
- Berens, Michael E.;
- Brenner, Charles;
- Bindra, Ranjit S.
Publication type:
Article
Proteomic Profiling of Retinoblastoma-Derived Exosomes Reveals Potential Biomarkers of Vitreous Seeding.
Published in:
Cancers, 2020, v. 12, n. 6, p. 1555, doi. 10.3390/cancers12061555
By:
- Galardi, Angela;
- Colletti, Marta;
- Lavarello, Chiara;
- Di Paolo, Virginia;
- Mascio, Paolo;
- Russo, Ida;
- Cozza, Raffaele;
- Romanzo, Antonino;
- Valente, Paola;
- De Vito, Rita;
- Pascucci, Luisa;
- Peinado, Hector;
- Carcaboso, Angel M.;
- Petretto, Andrea;
- Locatelli, Franco;
- Di Giannatale, Angela
Publication type:
Article
Reciprocal H3.3 gene editing identifies K27M and G34R mechanisms in pediatric glioma including NOTCH signaling.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-1076-0
By:
- Chen, Kuang-Yui;
- Bush, Kelly;
- Klein, Rachel Herndon;
- Cervantes, Vanessa;
- Lewis, Nichole;
- Naqvi, Aasim;
- Carcaboso, Angel M.;
- Lechpammer, Mirna;
- Knoepfler, Paul S.
Publication type:
Article
Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.
Published in:
Ecancermedicalscience, 2016, v. 10, n. 630-650, p. 1, doi. 10.3332/ecancer.2016.630
By:
- Nailor, Audrey;
- Walke, David A.;
- Jacque, Thomas S.;
- Warren, Kathy E.;
- Brem, Henry;
- Kearns, Pamela R.;
- Greenwood, John;
- Penny, Jeffrey I.;
- Pilkington, Geoffrey J.;
- Carcaboso, Angel M.;
- Fleischhack, Gudrun;
- Macarthur, Donald;
- Slavc, Irene;
- Meijer, Lisethe;
- Gill, Steven;
- Lowis, Stephen;
- van Vuurden, Dannis G.;
- Pearl, Monica S.;
- Clifford, Steven C.;
- Morrissy, Sorana
Publication type:
Article
Tissue Compatibility of SN‐38‐Loaded Anticancer Nanofiber Matrices.
Published in:
Advanced Healthcare Materials, 2018, v. 7, n. 15, p. 1, doi. 10.1002/adhm.201800255
By:
- Manzanares, Alejandro;
- Restrepo‐Perdomo, Camilo A.;
- Botteri, Gaia;
- Castillo‐Ecija, Helena;
- Pascual‐Pasto, Guillem;
- Cano, Francesc;
- Garcia‐Alvarez, Laura;
- Monterrubio, Carles;
- Ruiz, Bonaventura;
- Vazquez‐Carrera, Manuel;
- Suñol, Mariona;
- Mora, Jaume;
- Tornero, Jose A.;
- Sosnik, Alejandro;
- Carcaboso, Angel M.
Publication type:
Article
OKlahoma Nitrone-007: novel treatment for diffuse intrinsic pontine glioma.
Published in:
2020
By:
- Thomas, Lincy;
- Smith, Nataliya;
- Saunders, Debra;
- Zalles, Michelle;
- Gulej, Rafal;
- Lerner, Megan;
- Fung, Kar-Ming;
- Carcaboso, Angel M.;
- Towner, Rheal A.
Publication type:
journal article
Immune Response Generated With the Administration of Autologous Dendritic Cells Pulsed With an Allogenic Tumoral Cell-Lines Lysate in Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma.
Published in:
Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00127
By:
- Benitez-Ribas, Daniel;
- Cabezón, Raquel;
- Flórez-Grau, Georgina;
- Molero, Mari Carmen;
- Puerta, Patricia;
- Guillen, Antonio;
- González-Navarro, E. Azucena;
- Paco, Sonia;
- Carcaboso, Angel M.;
- Santa-Maria Lopez, Vicente;
- Cruz, Ofelia;
- de Torres, Carmen;
- Salvador, Noelia;
- Juan, Manel;
- Mora, Jaume;
- La Madrid, Andres Morales
Publication type:
Article
Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells.
Published in:
Cell Death & Disease, 2020, v. 11, n. 8, p. 1, doi. 10.1038/s41419-020-02800-7
By:
- Wiese, Maria;
- Hamdan, Feda H.;
- Kubiak, Klaudia;
- Diederichs, Christopher;
- Gielen, Gerrit H.;
- Nussbaumer, Gunther;
- Carcaboso, Angel M.;
- Hulleman, Esther;
- Johnsen, Steven A.;
- Kramm, Christof M.
Publication type:
Article
Intra-arterial chemotherapy for retinoblastoma. Challenges of a prospective study.
Published in:
Acta Ophthalmologica (1755375X), 2014, v. 92, n. 3, p. 209, doi. 10.1111/aos.12295
By:
- Parareda, Andreu;
- Català, Jaume;
- Carcaboso, Angel M.;
- Sola, Teresa;
- Cruz, Ofelia;
- Díaz, Jesús;
- Salvador, Héctor;
- Torres, Carmen;
- Álvarez‐Sampons, Alexandra;
- Suñol, Mariona;
- Vinent, Joan;
- Guimaraens, Leopoldo;
- Prat, Joan;
- Mora, Jaume
Publication type:
Article
Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0169485
By:
- Hennika, Tammy;
- Hu, Guo;
- Olaciregui, Nagore G.;
- Barton, Kelly L.;
- Ehteda, Anahid;
- Chitranjan, Arjanna;
- Chang, Cecilia;
- Gifford, Andrew J.;
- Tsoli, Maria;
- Ziegler, David S.;
- Carcaboso, Angel M.;
- Becher, Oren J.
Publication type:
Article
Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells.
Published in:
PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0160094
By:
- Winter, Ursula;
- Mena, Hebe A.;
- Negrotto, Soledad;
- Arana, Eloisa;
- Pascual-Pasto, Guillem;
- Laurent, Viviana;
- Suñol, Mariona;
- Chantada, Guillermo L.;
- Carcaboso, Angel M.;
- Schaiquevich, Paula
Publication type:
Article
Immunohistochemical expression of TFF1 is a marker of poor prognosis in retinoblastoma.
Published in:
Pediatric Blood & Cancer, 2024, v. 71, n. 1, p. 1, doi. 10.1002/pbc.30717
By:
- Aschero, Rosario;
- Ganiewich, Daiana;
- Lamas, Gabriela;
- Restrepo-Perdomo, Camilo A.;
- Ottaviani, Daniela;
- Zugbi, Santiago;
- Camarero, Sandra;
- Néspoli, Ezequiel;
- Vilanova, Maria Cuadrado;
- Perez-Jaume, Sara;
- Pascual-Pasto, Guillem;
- Sampor, Claudia;
- Grigorovski, Nathalia;
- Salas, Beatriz;
- Suñol, Mariona;
- Carcaboso, Angel M.;
- Mora, Jaume;
- de Dávila, María T. G.;
- Doz, François;
- Radvanyi, François
Publication type:
Article
Prognostic value of xenograft engraftment in patients with metastatic high‐risk neuroblastoma.
Published in:
Pediatric Blood & Cancer, 2023, v. 70, n. 6, p. 1, doi. 10.1002/pbc.30318
By:
- Aschero, Rosario;
- Castillo‐Ecija, Helena;
- Baulenas‐Farres, Merce;
- Resa‐Pares, Claudia;
- Jimenez‐Cabaco, Ana;
- Rodriguez, Eva;
- Monterrubio, Carles;
- Perez‐Jaume, Sara;
- Suñol, Mariona;
- Chantada, Guillermo L.;
- Lavarino, Cinzia;
- Mora, Jaume;
- Carcaboso, Angel M.
Publication type:
Article
Follow‐up of intraocular retinoblastoma through the quantitative analysis of conserved nuclear DNA sequences in aqueous humor from patients.
Published in:
Journal of Pathology: Clinical Research, 2023, v. 9, n. 1, p. 32, doi. 10.1002/cjp2.296
By:
- Cuadrado‐Vilanova, Maria;
- Burgueño, Victor;
- Balaguer‐Lluna, Leire;
- Aschero, Rosario;
- Castillo‐Ecija, Helena;
- Liu, Jing;
- Perez‐Jaume, Sara;
- Pascual‐Pasto, Guillem;
- Olaciregui, Nagore G;
- Gomez‐Gonzalez, Soledad;
- Correa, Genoveva;
- Suñol, Mariona;
- Schaiquevich, Paula;
- Radvanyi, François;
- Lavarino, Cinzia;
- Mora, Jaume;
- Catala‐Mora, Jaume;
- Chantada, Guillermo L;
- Carcaboso, Angel M
Publication type:
Article
Effective Detection and Monitoring of Glioma Using [ 18 F]FPIA PET Imaging.
Published in:
Biomedicines, 2021, v. 9, n. 7, p. 811, doi. 10.3390/biomedicines9070811
By:
- Vassileva, Vessela;
- Braga, Marta;
- Barnes, Chris;
- Przystal, Justyna;
- Ashek, Ali;
- Allott, Louis;
- Brickute, Diana;
- Abrahams, Joel;
- Suwan, Keittisak;
- Carcaboso, Angel M.;
- Hajitou, Amin;
- Aboagye, Eric O.
Publication type:
Article
Subconjunctival Carboplatin and Systemic Topotecan Treatment in Preclinical Models of Retinoblastoma.
Published in:
Cancer (0008543X), 2011, v. 117, n. 2, p. 421, doi. 10.1002/cncr.25574
By:
- Nemeth, Katie M.;
- Federico, Sara;
- Carcaboso, Angel M.;
- Ying Shen;
- Schaiquevich, Paula;
- Jiakun Zhang;
- Egorin, Merrill;
- Stewart, Clinton;
- Dyer, Michael A.
Publication type:
Article
MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment.
Published in:
2022
By:
- Garcia-Gerique, Laura;
- García, Marta;
- Garrido-Garcia, Alícia;
- Gómez-González, Soledad;
- Torrebadell, Montserrat;
- Prada, Estela;
- Pascual-Pasto, Guillem;
- Muñoz, Oscar;
- Perez-Jaume, Sara;
- Lemos, Isadora;
- Salvador, Noelia;
- Vila-Ubach, Monica;
- Doncel-Requena, Ana;
- Suñol, Mariona;
- Carcaboso, Angel M.;
- Mora, Jaume;
- Lavarino, Cinzia
Publication type:
journal article
PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo.
Published in:
Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-48652-x
By:
- Brown, Elizabeth J.;
- Balaguer-Lluna, Leire;
- Cribbs, Adam P.;
- Philpott, Martin;
- Campo, Leticia;
- Browne, Molly;
- Wong, Jong Fu;
- Oppermann, Udo;
- Carcaboso, Ángel M.;
- Bullock, Alex N.;
- Farnie, Gillian
Publication type:
Article

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