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Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite.
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- Microbial Biotechnology, 2011, v. 4, n. 2, p. 184, doi. 10.1111/j.1751-7915.2010.00209.x
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- Article
Precursor-Directed Biosynthesis: Stereospecificity for Branched-Chain Diketides of the β-Ketoacyl-ACP Synthase Domain 2 of 6-Deoxyerythronolide B Synthase.
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- Helvetica Chimica Acta, 2003, v. 86, n. 12, p. 3889
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- Article
Stereochemical Studies of Natural Products Biosynthesis<sup>a</sup>.
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- Annals of the New York Academy of Sciences, 1986, v. 471, n. 1, p. 130, doi. 10.1111/j.1749-6632.1986.tb48031.x
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- Article
Enhancing the Atom Economy of Polyketide Biosynthetic Processes through Metabolic Engineering.
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- Biotechnology Progress, 2001, v. 17, n. 4, p. 612, doi. 10.1021/bp010045j
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- Article
Incubation of 2-methylisoborneol synthase with the intermediate analog 2-methylneryl diphosphate.
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- Journal of Antibiotics, 2017, v. 70, n. 5, p. 625, doi. 10.1038/ja.2017.24
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- Article
Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases.
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- Journal of Antibiotics, 2016, v. 69, n. 7, p. 507, doi. 10.1038/ja.2016.41
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- Article
Nature as organic chemist.
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- Journal of Antibiotics, 2016, v. 69, n. 7, p. 473, doi. 10.1038/ja.2016.55
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- Article
Novel terpenes generated by heterologous expression of bacterial terpene synthase genes in an engineered Streptomyces host.
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- Journal of Antibiotics, 2015, v. 68, n. 6, p. 385, doi. 10.1038/ja.2014.171
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- Article
Improved precursor-directed biosynthesis in E. coli via directed evolution.
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- Journal of Antibiotics, 2011, v. 64, n. 1, p. 59, doi. 10.1038/ja.2010.129
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- Article
Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis.
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- Journal of Antibiotics, 2011, v. 64, n. 1, p. 65, doi. 10.1038/ja.2010.135
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- Article
Geosmin Biosynthesis in Streptomyces avermitilis. Molecular Cloning, Expression, and Mechanistic Study of the Germacradienol/Geosmin Synthase.
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- Journal of Antibiotics, 2006, v. 59, n. 8, p. 471, doi. 10.1038/ja.2006.66
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- Article
Chain Elongation, Macrolactonization, and Hydrolysis of Natural and Reduced Hexaketide Substrates by the Picromycin/Methymycin Polyketide Synthase.
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- Angewandte Chemie, 2005, v. 117, n. 46, p. 7729, doi. 10.1002/ange.200502246
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- Article
Biochemistry: Favouring the unfavoured.
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- 2012
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- Publication type:
- Opinion
Chain Elongation, Macrolactonization, and Hydrolysis of Natural and Reduced Hexaketide Substrates by the Picromycin/Methymycin Polyketide SynthaseThis research was supported by NIH Grants GM22172 (D.E.C) and CA66736 (C.K.).
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- Angewandte Chemie International Edition, 2005, v. 44, n. 46, p. 7557, doi. 10.1002/anie.200502246
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- Article
Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis.
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- Nature Structural Biology, 2001, v. 8, n. 7, p. 641
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- Article
Probing the interactions of an acyl carrier protein domain from the 6-deoxyerythronolide B synthase.
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- Protein Science: A Publication of the Protein Society, 2011, v. 20, n. 7, p. 1244, doi. 10.1002/pro.652
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- Article
Solution structure and proposed domain-domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase.
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- Protein Science: A Publication of the Protein Society, 2007, v. 16, n. 10, p. 2093, doi. 10.1110/ps.073011407
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- Article
Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme.
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- Nature Chemical Biology, 2007, v. 3, n. 11, p. 711, doi. 10.1038/nchembio.2007.29
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- Article
How to evolve a silk purse from a sow's ear.
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- Nature Chemical Biology, 2006, v. 2, n. 4, p. 179, doi. 10.1038/nchembio0406-179
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- Article
The Mode of Incorporation of Farnesyl Pyrophosphate into Verrucarol. Preliminary communication.
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- Helvetica Chimica Acta, 1973, v. 56, n. 8, p. 2946, doi. 10.1002/hlca.19730560834
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- Article