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Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole.
- Published in:
- 2016
- By:
- Publication type:
- journal article
A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model of the histone deacetylase (HDAC) inhibitor vorinostat for pediatric and adult patients and its application for dose specification.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Dose‐dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 8, p. 1, doi. 10.1111/cts.70007
- By:
- Publication type:
- Article
Reply to Truffot et al.
- Published in:
- 2018
- By:
- Publication type:
- Letter to the Editor
Potent cytochrome P450 2C19 genotype–related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2006, v. 80, n. 2, p. 126, doi. 10.1016/j.clpt.2006.04.004
- By:
- Publication type:
- Article
Opposite effects of short-term and long-term St John’s wort intake on voriconazole pharmacokinetics
- Published in:
- Clinical Pharmacology & Therapeutics, 2005, v. 78, n. 1, p. 25, doi. 10.1016/j.clpt.2005.01.024
- By:
- Publication type:
- Article
Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 1, p. 73, doi. 10.1016/j.clpt.2004.02.008
- By:
- Publication type:
- Article
Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 5, p. 397, doi. 10.1016/S0009-9236(03)00059-6
- By:
- Publication type:
- Article
Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 5, p. 405, doi. 10.1016/S0009-9236(01)35864-2
- By:
- Publication type:
- Article
Influence of St. John's wort on the steady-state pharmacokinetics and metabolism of bosentan.
- Published in:
- International Journal of Clinical Pharmacology & Therapeutics, 2014, v. 52, n. 4, p. 328, doi. 10.5414/CP202048
- By:
- Publication type:
- Article
Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Example.
- Published in:
- Molecules, 2022, v. 27, n. 3, p. 690, doi. 10.3390/molecules27030690
- By:
- Publication type:
- Article
Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives.
- Published in:
- Molecules, 2021, v. 26, n. 5, p. 1281, doi. 10.3390/molecules26051281
- By:
- Publication type:
- Article
An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids.
- Published in:
- Molecules, 2020, v. 25, n. 19, p. 4436, doi. 10.3390/molecules25194436
- By:
- Publication type:
- Article
The Effect of Induction of CYP3A4 by St John's Wort on Ambrisentan Plasma Pharmacokinetics in Volunteers of known CYP2C19 Genotype.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 5, p. 423, doi. 10.1111/bcpt.12332
- By:
- Publication type:
- Article
Pre-systemic Elimination of Tilidine: Localization and Consequences for the Formation of the Active Metabolite Nortilidine.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 2, p. 129, doi. 10.1111/bcpt.12328
- By:
- Publication type:
- Article
Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34674-3
- By:
- Publication type:
- Article
Substantial Impairment of Voriconazole Clearance by High-Dose Meropenem in a Patient With Renal Failure.
- Published in:
- Clinical Infectious Diseases, 2017, v. 65, n. 6, p. 1033, doi. 10.1093/cid/cix443
- By:
- Publication type:
- Article
Efavirenz Treatment and False-Positive Results in Benzodiazepine Screening Tests.
- Published in:
- Clinical Infectious Diseases, 2009, v. 48, n. 12, p. 1787, doi. 10.1086/599109
- By:
- Publication type:
- Article
Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP).
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 4118, doi. 10.3390/ijms25074118
- By:
- Publication type:
- Article
Desorption Kinetics Evaluation for the Development of Validated Desorption Electrospray Ionization-Mass Spectrometric Assays for Drug Quantification in Tissue Sections.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8469, doi. 10.3390/ijms24108469
- By:
- Publication type:
- Article
Correction: Bay et al. Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC3A2) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine. Int. J. Mol. Sci. 2022, 23 , 3637
- Published in:
- 2023
- By:
- Publication type:
- Correction Notice
Metabolic Effect of Blocking Sodium-Taurocholate Co-Transporting Polypeptide in Hypercholesterolemic Humans with a Twelve-Week Course of Bulevirtide—An Exploratory Phase I Clinical Trial.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15924, doi. 10.3390/ijms232415924
- By:
- Publication type:
- Article
Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC2A3) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3637, doi. 10.3390/ijms23073637
- By:
- Publication type:
- Article
Ceritinib-Induced Regression of an Insulin-Like Growth Factor-Driven Neuroepithelial Brain Tumor.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 17, p. 4267, doi. 10.3390/ijms20174267
- By:
- Publication type:
- Article
Accumulation of the solvent vehicle sulphobutylether beta cyclodextrin sodium in critically ill patients treated with intravenous voriconazole under renal replacement therapy.
- Published in:
- BMC Clinical Pharmacology, 2006, v. 6, p. 6, doi. 10.1186/1472-6904-6-6
- By:
- Publication type:
- Article
Plasma Drug Concentrations in Patients with Pulmonary Arterial Hypertension on Combination Treatment.
- Published in:
- Respiration, 2017, v. 94, n. 1, p. 26, doi. 10.1159/000470916
- By:
- Publication type:
- Article
A Nanocarrier Approach for Oral Peptide Delivery: Evaluation of Cell‐Penetrating‐Peptide‐Modified Liposomal Formulations in Dogs.
- Published in:
- Advanced Therapeutics, 2023, v. 6, n. 10, p. 1, doi. 10.1002/adtp.202300021
- By:
- Publication type:
- Article
<italic>In Vivo</italic> CYP3A Activity in Palliative Care Patients: Study Protocol for a Single Arm Prospective Trial.
- Published in:
- Journal of Palliative Medicine, 2018, v. 21, n. 5, p. 686, doi. 10.1089/jpm.2017.0461
- By:
- Publication type:
- Article
Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans.
- Published in:
- European Journal of Clinical Pharmacology, 2022, v. 78, n. 6, p. 975, doi. 10.1007/s00228-022-03304-3
- By:
- Publication type:
- Article
Concentration effect relationship of CYP3A inhibition by ritonavir in humans.
- Published in:
- European Journal of Clinical Pharmacology, 2013, v. 69, n. 10, p. 1795, doi. 10.1007/s00228-013-1530-8
- By:
- Publication type:
- Article
Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.
- Published in:
- European Journal of Clinical Pharmacology, 2013, v. 69, n. 10, p. 1785, doi. 10.1007/s00228-013-1529-1
- By:
- Publication type:
- Article
Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity.
- Published in:
- European Journal of Clinical Pharmacology, 2013, v. 69, n. 3, p. 507, doi. 10.1007/s00228-012-1388-1
- By:
- Publication type:
- Article
CytochromeP<sub>450</sub> enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m).
- Published in:
- European Journal of Clinical Pharmacology, 2005, v. 61, n. 1, p. 39, doi. 10.1007/s00228-004-0886-1
- By:
- Publication type:
- Article
Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria.
- Published in:
- European Journal of Clinical Pharmacology, 2004, v. 60, n. 10, p. 709, doi. 10.1007/s00228-004-0818-0
- By:
- Publication type:
- Article
Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter-based drug-drug interactions.
- Published in:
- Oncology Letters, 2017, v. 14, n. 3, p. 3185, doi. 10.3892/ol.2017.6560
- By:
- Publication type:
- Article
Effect of Tacrolimus Formulation (Prolonged‐Release vs Immediate‐Release) on Its Susceptibility to Drug‐Drug Interactions with St. John's Wort.
- Published in:
- Clinical Pharmacology in Drug Development, 2024, v. 13, n. 3, p. 297, doi. 10.1002/cpdd.1364
- By:
- Publication type:
- Article
Effect of Pantoprazole on the Absorption of Hydroxychloroquinea A Randomized Drug‐Drug Interaction Trial in Healthy Adults.
- Published in:
- Clinical Pharmacology in Drug Development, 2022, v. 11, n. 2, p. 285, doi. 10.1002/cpdd.999
- By:
- Publication type:
- Article
Differential Effect of a Continental Breakfast on Tacrolimus Formulations With Different Release Characteristics.
- Published in:
- Clinical Pharmacology in Drug Development, 2021, v. 10, n. 8, p. 899, doi. 10.1002/cpdd.924
- By:
- Publication type:
- Article
Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00026
- By:
- Publication type:
- Article
Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19): A structured summary of a study protocol for a randomised controlled trial.
- Published in:
- 2020
- By:
- Publication type:
- letter
In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo–keto reductases.
- Published in:
- Archives of Toxicology, 2024, v. 98, n. 3, p. 807, doi. 10.1007/s00204-023-03661-7
- By:
- Publication type:
- Article
Steady-state pharmacokinetics and metabolism of voriconazole in patients.
- Published in:
- 2013
- By:
- Publication type:
- Journal Article
Steady-state pharmacokinetics and metabolism of voriconazole in patients.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 11, p. 2592, doi. 10.1093/jac/dkt229
- By:
- Publication type:
- Article
Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2011, v. 66, n. 10, p. 2350, doi. 10.1093/jac/dkr304
- By:
- Publication type:
- Article
Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways.
- Published in:
- BMC Pharmacology & Toxicology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s40360-019-0331-9
- By:
- Publication type:
- Article
Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers.
- Published in:
- Clinical Pharmacokinetics, 2024, v. 63, n. 4, p. 469, doi. 10.1007/s40262-024-01350-x
- By:
- Publication type:
- Article
CYP3A and CYP2C19 Activity Determined by Microdosed Probe Drugs Accurately Predict Voriconazole Clearance in Healthy Adults.
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 9, p. 1305, doi. 10.1007/s40262-023-01287-7
- By:
- Publication type:
- Article
Quantification of the Time Course of CYP3A Inhibition, Activation, and Induction Using a Population Pharmacokinetic Model of Microdosed Midazolam Continuous Infusion.
- Published in:
- Clinical Pharmacokinetics, 2022, v. 61, n. 11, p. 1595, doi. 10.1007/s40262-022-01175-6
- By:
- Publication type:
- Article