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Digital Therapeutics (DTx) Expand Multimodal Treatment Options for Chronic Low Back Pain: The Nexus of Precision Medicine, Patient Education, and Public Health.
- Published in:
- Healthcare (2227-9032), 2023, v. 11, n. 10, p. 1469, doi. 10.3390/healthcare11101469
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- Publication type:
- Article
Music-Enhanced Analgesia and Antiseizure Activities in Animal Models of Pain and Epilepsy: Toward Preclinical Studies Supporting Development of Digital Therapeutics and Their Combinations With Pharmaceutical Drugs.
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- Frontiers in Neurology, 2019, p. N.PAG, doi. 10.3389/fneur.2019.00277
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- Publication type:
- Article
Selenopeptide Analogs of EETI-II Retain Potent Trypsin Inhibitory Activities.
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- Chemical Biology & Drug Design, 2011, v. 77, n. 1, p. 93, doi. 10.1111/j.1747-0285.2010.01046.x
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- Publication type:
- Article
Improving Fmoc Solid Phase Synthesis of Human Beta Defensin 3.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12562, doi. 10.3390/ijms232012562
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- Publication type:
- Article
Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily.
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- FEBS Journal, 2005, v. 272, n. 16, p. 4178, doi. 10.1111/j.1742-4658.2005.04830.x
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- Publication type:
- Article
Oxidative folding of conotoxins sharing an identical disulfide bridging framework.
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- FEBS Journal, 2005, v. 272, n. 7, p. 1727, doi. 10.1111/j.1742-4658.2005.04602.x
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- Publication type:
- Article
Reagentless Oxidative Folding of Disulfide-Rich Peptides Catalyzed by an Intramolecular Diselenide.
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 23, p. 5678, doi. 10.1002/ange.201200062
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- Publication type:
- Article
From Precision Metapharmacology to Patient Empowerment: Delivery of Self-Care Practices for Epilepsy, Pain, Depression and Cancer Using Digital Health Technologies.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.612602
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- Publication type:
- Article
On the Importance of Oxidative Folding in the Evolution of Conotoxins: Cysteine Codon Preservation through Gene Duplication and Adaptation.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078456
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- Publication type:
- Article
The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells.
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- Journal of Neuroscience Research, 2017, v. 95, n. 11, p. 2286, doi. 10.1002/jnr.24057
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- Publication type:
- Article
Mobile Software as a Medical Device (SaMD) for the Treatment of Epilepsy: Development of Digital Therapeutics Comprising Behavioral and Music-Based Interventions for Neurological Disorders.
- Published in:
- Frontiers in Human Neuroscience, 2018, p. 1, doi. 10.3389/fnhum.2018.00171
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- Publication type:
- Article
Healthy Dwelling: Design of Biophilic Interior Environments Fostering Self-Care Practices for People Living with Migraines, Chronic Pain, and Depression.
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- International Journal of Environmental Research & Public Health, 2022, v. 19, n. 4, p. 2248, doi. 10.3390/ijerph19042248
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- Publication type:
- Article
The Cys-Xaa-His metal-binding motif: {N} versus {S} coordination and nickel-mediated formation of cysteinyl sulfinic acid.
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- Journal of Biological Inorganic Chemistry (JBIC), 2003, v. 8, n. 6, p. 601, doi. 10.1007/s00775-003-0454-7
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- Publication type:
- Article
Digital Therapeutics for Improving Effectiveness of Pharmaceutical Drugs and Biological Products: Preclinical and Clinical Studies Supporting Development of Drug + Digital Combination Therapies for Chronic Diseases.
- Published in:
- Journal of Clinical Medicine, 2024, v. 13, n. 2, p. 403, doi. 10.3390/jcm13020403
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- Publication type:
- Article
Optimization of oxidative folding methods for cysteine-rich peptides: a study of conotoxins containing three disulfide bridges.
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- Journal of Peptide Science, 2011, v. 17, n. 1, p. 1, doi. 10.1002/psc.1283
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- Publication type:
- Article
Introduction of lipidization-cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities.
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- Journal of Peptide Science, 2010, v. 16, n. 9, p. 486, doi. 10.1002/psc.1266
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- Publication type:
- Article
Characterization of conantokin Rl-A: molecular phylogeny as structure/function study.
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- Journal of Peptide Science, 2010, v. 16, n. 8, p. 375, doi. 10.1002/psc.1249
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- Publication type:
- Article
Cosolvent-assisted oxidative folding of a bicyclic α-conotoxin ImI.
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- Journal of Peptide Science, 2004, v. 10, n. 5, p. 249, doi. 10.1002/psc.531
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- Publication type:
- Article
Synergistic effects of the galanin analog 810–2 with the antiseizure medication levetiracetam in rodent seizure models.
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- Epilepsia (Series 4), 2022, v. 63, n. 12, p. 3090, doi. 10.1111/epi.17420
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- Publication type:
- Article
Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics.
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- Epilepsia (Series 4), 2017, v. 58, n. 2, p. 239, doi. 10.1111/epi.13647
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- Publication type:
- Article
Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin Bu IIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3.
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- 2014
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- Publication type:
- Editorial
A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties.
- Published in:
- Frontiers in Pharmacology, 2015, v. 6, p. 1, doi. 10.3389/fphar.2015.00011
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- Publication type:
- Article
Preclinical Analgesic and Safety Evaluation of the GalR2-preferring Analog, NAX 810-2.
- Published in:
- Neurochemical Research, 2017, v. 42, n. 7, p. 1983, doi. 10.1007/s11064-017-2229-5
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- Publication type:
- Article
Patient-Empowerment Interactive Technologies.
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- Science Translational Medicine, 2012, v. 4, n. 152, p. 1, doi. 10.1126/scitranslmed.3004009
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- Publication type:
- Article
Albumin is a redox-active crowding agent that promotes oxidative folding of cysteine-rich peptides.
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- Biopolymers, 2007, v. 88, n. 1, p. 8, doi. 10.1002/bip.20615
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- Publication type:
- Article
Total chemical synthesis and oxidative folding of δ-conotoxin PVIA containing an N-terminal propeptide.
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- Biopolymers, 2005, v. 80, n. 1, p. 50, doi. 10.1002/bip.20211
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- Publication type:
- Article
Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins.
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- 2013
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- Publication type:
- journal article
Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins.
- Published in:
- British Journal of Pharmacology, 2013, v. 169, n. 1, p. 102, doi. 10.1111/bph.12119
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- Publication type:
- Article
Co-expression of Na<sub>V</sub>β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins.
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- British Journal of Pharmacology, 2013, v. 168, n. 7, p. 1597, doi. 10.1111/bph.12051
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- Publication type:
- Article
φ-Values for BPTI folding intermediates and implications for transition state analysis.
- Published in:
- Nature Structural Biology, 2001, v. 8, n. 4, p. 326, doi. 10.1038/86200
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- Publication type:
- Article
Redesigning Pharmacy to Improve Public Health Outcomes: Expanding Retail Spaces for Digital Therapeutics to Replace Consumer Products That Increase Mortality and Morbidity Risks.
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- Pharmacy, 2024, v. 12, n. 4, p. 107, doi. 10.3390/pharmacy12040107
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- Publication type:
- Article
Improving Self-Esteem With Motivational Quotes: Opportunities for Digital Health Technologies for People With Chronic Disorders.
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- Frontiers in Psychology, 2018, p. N.PAG, doi. 10.3389/fpsyg.2018.02126
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- Publication type:
- Article
Combining non-pharmacological treatments with pharmacotherapies for neurological disorders: a unique interface of the brain, drug-device, and intellectual property.
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- Frontiers in Neurology, 2014, v. 5, p. 1, doi. 10.3389/fneur.2014.00126
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- Publication type:
- Article
Generating Orally Active Galanin Analogues with Analgesic Activities.
- Published in:
- ChemMedChem, 2012, v. 7, n. 5, p. 903, doi. 10.1002/cmdc.201100574
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- Publication type:
- Article
Glycosylated Neurotensin Analogues Exhibit Sub-picomolar Anticonvulsant Potency in a Pharmacoresistant Model of Epilepsy.
- Published in:
- ChemMedChem, 2009, v. 4, n. 3, p. 400, doi. 10.1002/cmdc.200800421
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- Publication type:
- Article
Structurally Minimized μ-Conotoxin Analogues as Sodium Channel Blockers: Implications for Designing Conopeptide-Based Therapeutics.
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- ChemMedChem, 2009, v. 4, n. 3, p. 406, doi. 10.1002/cmdc.200800292
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- Publication type:
- Article
The μO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3
- Published in:
- FEBS Letters, 2006, v. 580, n. 5, p. 1360, doi. 10.1016/j.febslet.2006.01.057
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- Publication type:
- Article
Alteration of the disulfide-coupled folding pathway of BPTI by circular permutation.
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- Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 5, p. 1182, doi. 10.1110/ps.03563704
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- Publication type:
- Article
Early events in the disulfide-coupled folding of BPTI.
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- Protein Science: A Publication of the Protein Society, 1999, v. 8, n. 9, p. 1825, doi. 10.1110/ps.8.9.1825
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- Publication type:
- Article
Dissecting a role of evolutionary-conserved but noncritical disulfide bridges in cysteine-rich peptides using ω-conotoxin GVIA and its selenocysteine analogs.
- Published in:
- Biopolymers, 2012, v. 98, n. 3, p. 212, doi. 10.1002/bip.22047
- By:
- Publication type:
- Article
Reagentless Oxidative Folding of Disulfide-Rich Peptides Catalyzed by an Intramolecular Diselenide.
- Published in:
- Angewandte Chemie International Edition, 2012, v. 51, n. 23, p. 5580, doi. 10.1002/anie.201200062
- By:
- Publication type:
- Article
Integrated Oxidative Folding of Cysteine/Selenocysteine Containing Peptides: Improving Chemical Synthesis of Conotoxins.
- Published in:
- Angewandte Chemie International Edition, 2009, v. 48, n. 12, p. 2221, doi. 10.1002/anie.200806085
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- Publication type:
- Article