OpenURL Connection Search

Select item for more details and to access through your institution.

Inno4Vac Workshop Report Part 2: RSV‐Controlled Human Infection Model (CHIM) Strain Selection and Immune Assays for RSV CHIM Studies, November 2021, MHRA, UK.
Published in:
Influenza & Other Respiratory Viruses, 2024, v. 18, n. 10, p. 1, doi. 10.1111/irv.70013
By:
- Waldock, Joanna;
- Cox, Rebecca J.;
- Engelhardt, Othmar G.;
- Ascough, Stephanie;
- Osterhaus, Albert;
- Rimmelzwaan, Guus F.;
- Ludlow, Martin;
- Tregoning, John S.;
- McDonald, Jacqueline U.;
- Buchholz, Ursula J.;
- Jeeninga, Rienk E.;
- Sande, Charles.;
- Chiu, Christopher
Publication type:
Article
2777. Live-Attenuated Vaccine Against RSV Generates Robust Cellular and Humoral Immune Responses.
Published in:
Open Forum Infectious Diseases, 2019, v. 6, p. S980, doi. 10.1093/ofid/ofz360.2454
By:
- Mueller, Steffen;
- Nouen, Cyril Le;
- Buchholz, Ursula J;
- Kalkeri, Raj;
- Koide, Fusataka;
- Collins, Peter;
- Coleman, J Robert
Publication type:
Article
Evaluation of a Live Attenuated Human Metapneumovirus Vaccine in Adults and Children.
Published in:
Journal of the Pediatric Infectious Diseases Society, 2018, v. 7, n. 1, p. 86, doi. 10.1093/jpids/pix006
By:
- Karron, Ruth A.;
- Jocelyn San Mateo;
- Wanionek, Kimberli;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
Article
Evaluation of a Live-Attenuated Human Parainfluenza Type 1 Vaccine in Adults and Children.
Published in:
Journal of the Pediatric Infectious Diseases Society, 2015, v. 4, n. 4, p. e143, doi. 10.1093/jpids/piu104
By:
- Karron, Ruth A.;
- Mateo, Jocelyn San;
- Thumar, Bhagvanji;
- Schaap-Nutt, Anne;
- Buchholz, Ursula J.;
- Schmidt, Alexander C.;
- Bartlett, Emmalene J.;
- Murphy, Brian R.;
- Collins, Peter L.
Publication type:
Article
Addendum to Proposal for Human Respiratory Syncytial Virus Nomenclature below the Species Level.
Published in:
2022
By:
- Barr, Ian G.;
- Williams, Thomas C.;
- Salimi, Vahid;
- Buchholz, Ursula J.
Publication type:
Letter
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques.
Published in:
PLoS Pathogens, 2024, v. 0, n. 7, p. 1, doi. 10.1371/journal.ppat.1012339
By:
- Nelson, Christine E.;
- Foreman, Taylor W.;
- Fukutani, Eduardo R.;
- Kauffman, Keith D.;
- Sakai, Shunsuke;
- Fleegle, Joel D.;
- Gomez, Felipe;
- Gould, Sydnee T.;
- Le Nouën, Cyril;
- Liu, Xueqiao;
- Burdette, Tracey L.;
- Garza, Nicole L.;
- Lafont, Bernard A. P.;
- Brooks, Kelsie;
- Lindestam Arlehamn, Cecilia S.;
- Weiskopf, Daniela;
- Sette, Alessandro;
- Hickman, Heather D.;
- Buchholz, Ursula J.;
- Johnson, Reed F.
Publication type:
Article
Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters.
Published in:
PLoS Pathogens, 2024, v. 20, n. 5, p. 1, doi. 10.1371/journal.ppat.1012198
By:
- Levy, Megan;
- Chen, Jessica W.;
- Kaiser, Jaclyn A.;
- Park, Hong-Su;
- Liu, Xueqiao;
- Yang, Lijuan;
- Santos, Celia;
- Buchholz, Ursula J.;
- Le Nouën, Cyril
Publication type:
Article
TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 571, doi. 10.1172/JCI75183
By:
- Caballero, Mauricio T.;
- Serra, M. Elina;
- Acosta, Patricio L.;
- Marzec, Jacqui;
- Gibbons, Luz;
- Salim, Maximiliano;
- Rodriguez, Andrea;
- Reynaldi, Andrea;
- Garcia, Alejandro;
- Bado, Daniela;
- Buchholz, Ursula J.;
- Hijano, Diego R.;
- Coviello, Silvina;
- Newcomb, Dawn;
- Bellabarba, Miguel;
- Ferolla, Fausto M.;
- Libster, Romina;
- Berenstein, Ada;
- Siniawaski, Susana;
- Blumetti, Valeria
Publication type:
Article
RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 5, p. 2219, doi. 10.1172/JCI72948
By:
- Liesman, Rachael M.;
- Buchholz, Ursula J.;
- Luongo, Cindy L.;
- Lijuan Yang;
- Proia, Alan D.;
- DeVincenzo, John P.;
- Collins, Peter L.;
- Pickles, Raymond J.
Publication type:
Article
Mutations in the F protein of the live-attenuated respiratory syncytial virus vaccine candidate ΔNS2/Δ1313/I1314L increase the stability of infectivity and content of prefusion F protein.
Published in:
PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0301773
By:
- Alamares-Sapuay, Judith;
- Kishko, Michael;
- Lai, Charles;
- Parrington, Mark;
- Delagrave, Simon;
- Herbert, Richard;
- Castens, Ashley;
- Swerczek, Joanna;
- Luongo, Cindy;
- Yang, Lijuan;
- Collins, Peter L.;
- Buchholz, Ursula J.;
- Zhang, Linong
Publication type:
Article
Evaluation of the Replication, Pathogenicity, and Immunogenicity of Avian Paramyxovirus (APMV) Serotypes 2, 3, 4, 5, 7, and 9 in Rhesus Macaques.
Published in:
PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0075456
By:
- Khattar, Sunil K.;
- Nayak, Baibaswata;
- Kim, Shin-Hee;
- Xiao, Sa;
- Samal, Sweety;
- Paldurai, Anandan;
- Buchholz, Ursula J.;
- Collins, Peter L.;
- Samal, Siba K.
Publication type:
Article
Effects of Human Respiratory Syncytial Virus, Metapneumovirus, Parainfluenza Virus 3 and Influenza Virus on CD4+ T Cell Activation by Dendritic Cells.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015017
By:
- Le Nouën, Cyril;
- Hillyer, Philippa;
- Munir, Shirin;
- Winter, Christine C.;
- McCarty, Thomas;
- Bukreyev, Alexander;
- Collins, Peter L.;
- Rabin, Ronald L.;
- Buchholz, Ursula J.
Publication type:
Article
Experimental Infection of Adults With Recombinant Wild-Type Human Metapneumovirus.
Published in:
Journal of Infectious Diseases, 2013, v. 208, n. 10, p. 1669, doi. 10.1093/infdis/jit356
By:
- Talaat, Kawsar R.;
- Karron, Ruth A.;
- Thumar, Bhagvanji;
- McMahon, Bridget A.;
- Schmidt, Alexander C.;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
Article
Attenuation of Live Respiratory Syncytial Virus Vaccines Is Associated With Reductions in Levels of Nasal Cytokines.
Published in:
Journal of Infectious Diseases, 2013, v. 207, n. 11, p. 1773, doi. 10.1093/infdis/jit089
By:
- Karron, Ruth A.;
- Thumar, Bhagvanji;
- Schappell, Elizabeth;
- Buchholz, Ursula J.;
- Collins, Peter L.
Publication type:
Article
Live-attenuated Vaccines Prevent Respiratory Syncytial Virus-associated Illness in Young Children.
Published in:
2021
By:
- Karron, Ruth A.;
- Atwell, Jessica E.;
- McFarland, Elizabeth J.;
- Cunningham, Coleen K.;
- Muresan, Petronella;
- Perlowski, Charlotte;
- Libous, Jennifer;
- Spector, Stephen A.;
- Yogev, Ram;
- Aziz, Mariam;
- Woods, Suzanne;
- Wanionek, Kimberli;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
journal article
Reversion mutations in phosphoprotein P of a codon-pair-deoptimized human respiratory syncytial virus confer increased transcription, immunogenicity, and genetic stability without loss of attenuation.
Published in:
PLoS Pathogens, 2021, v. 17, n. 12, p. 1, doi. 10.1371/journal.ppat.1010191
By:
- Chen, Jessica W.;
- Yang, Lijuan;
- Santos, Celia;
- Hassan, Sergio A.;
- Collins, Peter L.;
- Buchholz, Ursula J.;
- Le Nouën, Cyril
Publication type:
Article
Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01250
By:
- Le Nouën, Cyril;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
Article
Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report.
Published in:
NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00654-6
By:
- Knisely, Jane M.;
- Buyon, Lucas E.;
- Mandt, Rebecca;
- Farkas, Rebecca;
- Balasingam, Shobana;
- Bok, Karin;
- Buchholz, Ursula J.;
- D'Souza, M. Patricia;
- Gordon, Jennifer L.;
- King, Deborah F. L.;
- Le, Tung T.;
- Leitner, Wolfgang W.;
- Seder, Robert A.;
- Togias, Alkis;
- Tollefsen, Stig;
- Vaughn, David W.;
- Wolfe, Daniel N.;
- Taylor, Kimberly L.;
- Fauci, Anthony S.
Publication type:
Article
Taxonomy of the order Mononegavirales: update 2019.
Published in:
Archives of Virology, 2019, v. 164, n. 7, p. 1967, doi. 10.1007/s00705-019-04247-4
By:
- Amarasinghe, Gaya K.;
- Ayllón, María A.;
- Bào, Yīmíng;
- Basler, Christopher F.;
- Bavari, Sina;
- Blasdell, Kim R.;
- Briese, Thomas;
- Brown, Paul A.;
- Bukreyev, Alexander;
- Balkema-Buschmann, Anne;
- Buchholz, Ursula J.;
- Chabi-Jesus, Camila;
- Chandran, Kartik;
- Chiapponi, Chiara;
- Crozier, Ian;
- de Swart, Rik L.;
- Dietzgen, Ralf G.;
- Dolnik, Olga;
- Drexler, Jan F.;
- Dürrwald, Ralf
Publication type:
Article
Taxonomy of the order Mononegavirales: second update 2018.
Published in:
Archives of Virology, 2019, v. 164, n. 4, p. 1233, doi. 10.1007/s00705-018-04126-4
By:
- Maes, Piet;
- Amarasinghe, Gaya K.;
- Ayllón, María A.;
- Basler, Christopher F.;
- Bavari, Sina;
- Blasdell, Kim R.;
- Briese, Thomas;
- Brown, Paul A.;
- Bukreyev, Alexander;
- Balkema-Buschmann, Anne;
- Buchholz, Ursula J.;
- Chandran, Kartik;
- Crozier, Ian;
- de Swart, Rik L.;
- Dietzgen, Ralf G.;
- Dolnik, Olga;
- Domier, Leslie L.;
- Drexler, Jan F.;
- Dürrwald, Ralf;
- Dundon, William G.
Publication type:
Article
Evaluation of a Live-Attenuated Human Parainfluenza Virus Type 2 Vaccine in Adults and Children.
Published in:
Journal of the Pediatric Infectious Diseases Society, 2023, v. 12, n. 3, p. 173, doi. 10.1093/jpids/piac137
By:
- Karron, Ruth A;
- Herbert, Kristi;
- Wanionek, Kimberli;
- Schmidt, Alexander C;
- Schaap-Nutt, Anne;
- Collins, Peter L;
- Buchholz, Ursula J
Publication type:
Article
A gene deletion that up-regulates viral gene expression yields an attenuated RSV vaccine with improved antibody responses in children.
Published in:
Science Translational Medicine, 2015, v. 7, n. 312, p. 1, doi. 10.1126/scitranslmed.aac8463
By:
- Karron, Ruth A.;
- Luongo, Cindy;
- Thumar, Bhagvanji;
- Loehr, Karen M.;
- Englund, Janet A.;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
Article
Low CCR7-Mediated Migration of Human Monocyte Derived Dendritic Cells in Response to Human Respiratory Syncytial Virus and Human Metapneumovirus.
Published in:
PLoS Pathogens, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.ppat.1002105
By:
- Le Nouën, Cyril;
- Hillyer, Philippa;
- Winter, Christine C.;
- McCarty, Thomas;
- Rabin, Ronald L.;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
Article
Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response.
Published in:
PLoS Pathogens, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.ppat.1001336
By:
- Munir, Shirin;
- Hillyer, Philippa;
- Nouën, Cyril Le;
- Buchholz, Ursula J.;
- Rabin, Ronald L.;
- Collins, Peter L.;
- Bukreyev, Alexander
Publication type:
Article
Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread.
Published in:
PLoS Pathogens, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.ppat.1006062
By:
- Mehedi, Masfique;
- McCarty, Thomas;
- Martin, Scott E.;
- Le Nouën, Cyril;
- Buehler, Eugen;
- Chen, Yu-Chi;
- Smelkinson, Margery;
- Ganesan, Sundar;
- Fischer, Elizabeth R.;
- Brock, Linda G.;
- Liang, Bo;
- Munir, Shirin;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
Article
Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell Spread.
Published in:
PLoS Pathogens, 2016, v. 12, n. 9, p. 1, doi. 10.1371/journal.ppat.1005922
By:
- El Najjar, Farah;
- Cifuentes-Muñoz, Nicolás;
- Chen, Jing;
- Zhu, Haining;
- Buchholz, Ursula J.;
- Moncman, Carole L.;
- Dutch, Rebecca Ellis
Publication type:
Article
Intranasal immunization with avian paramyxovirus type 3 expressing SARS-CoV-2 spike protein protects hamsters against SARS-CoV-2.
Published in:
NPJ Vaccines, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41541-022-00493-x
By:
- Park, Hong-Su;
- Matsuoka, Yumiko;
- Luongo, Cindy;
- Yang, Lijuan;
- Santos, Celia;
- Liu, Xueqiao;
- Ahlers, Laura R. H.;
- Moore, Ian N.;
- Afroz, Sharmin;
- Johnson, Reed F.;
- Lafont, Bernard A. P.;
- Dorward, David W.;
- Fischer, Elizabeth R.;
- Martens, Craig;
- Samal, Siba K.;
- Munir, Shirin;
- Buchholz, Ursula J.;
- Le Nouën, Cyril
Publication type:
Article
Elicitation of pneumovirus-specific B cell responses by a prefusion-stabilized respiratory syncytial virus F subunit vaccine.
Published in:
Science Translational Medicine, 2022, v. 14, n. 650, p. 1, doi. 10.1126/scitranslmed.abo5032
By:
- Phung, Emily;
- Chang, Lauren A.;
- Mukhamedova, Maryam;
- Yang, Lijuan;
- Nair, Deepika;
- Rush, Scott A.;
- Morabito, Kaitlyn M.;
- McLellan, Jason S.;
- Buchholz, Ursula J.;
- Mascola, John R.;
- Crank, Michelle C.;
- Chen, Grace;
- Graham, Barney S.;
- Ruckwardt, Tracy J.
Publication type:
Article
Evaluation of the Live-Attenuated Intranasal Respiratory Syncytial Virus (RSV) Vaccine RSV/6120/ΔNS2/1030s in RSV-Seronegative Young Children.
Published in:
Journal of Infectious Diseases, 2024, v. 229, n. 2, p. 346, doi. 10.1093/infdis/jiad281
By:
- Karron, Ruth A;
- Luongo, Cindy;
- Woods, Suzanne;
- Oliva, Jennifer;
- Collins, Peter L;
- Buchholz, Ursula J;
- Team, the RSVPed
Publication type:
Article
Safety and Immunogenicity of the Respiratory Syncytial Virus Vaccine RSV/ΔNS2/Δ1313/I1314L in RSV-Seronegative Children.
Published in:
Journal of Infectious Diseases, 2020, v. 222, n. 1, p. 82, doi. 10.1093/infdis/jiz408
By:
- Karron, Ruth A;
- Luongo, Cindy;
- Mateo, Jocelyn San;
- Wanionek, Kimberli;
- Collins, Peter L;
- Buchholz, Ursula J
Publication type:
Article
Safety and Immunogenicity of the Respiratory Syncytial Virus Vaccine RSV/ΔNS2/Δ1313/I1314L in RSV-Seronegative Children.
Published in:
2020
By:
- Karron, Ruth A;
- Luongo, Cindy;
- Mateo, Jocelyn San;
- Wanionek, Kimberli;
- Collins, Peter L;
- Buchholz, Ursula J
Publication type:
journal article
Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children.
Published in:
Journal of Infectious Diseases, 2020, v. 221, n. 12, p. 2050, doi. 10.1093/infdis/jiaa049
By:
- McFarland, Elizabeth J;
- Karron, Ruth A;
- Muresan, Petronella;
- Cunningham, Coleen K;
- Perlowski, Charlotte;
- Libous, Jennifer;
- Oliva, Jennifer;
- Jean-Philippe, Patrick;
- Moye, Jack;
- Schappell, Elizabeth;
- Barr, Emily;
- Rexroad, Vivian;
- Fearn, Laura;
- Cielo, Mikhaela;
- Wiznia, Andrew;
- Deville, Jaime G;
- Yang, Lijuan;
- Luongo, Cindy;
- Collins, Peter L;
- Buchholz, Ursula J
Publication type:
Article
Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children.
Published in:
2020
By:
- McFarland, Elizabeth J;
- Karron, Ruth A;
- Muresan, Petronella;
- Cunningham, Coleen K;
- Perlowski, Charlotte;
- Libous, Jennifer;
- Oliva, Jennifer;
- Jean-Philippe, Patrick;
- Moye, Jack;
- Schappell, Elizabeth;
- Barr, Emily;
- Rexroad, Vivian;
- Fearn, Laura;
- Cielo, Mikhaela;
- Wiznia, Andrew;
- Deville, Jaime G;
- Yang, Lijuan;
- Luongo, Cindy;
- Collins, Peter L;
- Buchholz, Ursula J
Publication type:
journal article
Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children.
Published in:
2018
By:
- Buchholz, Ursula J.;
- Cunningham, Coleen K.;
- Muresan, Petronella;
- Gnanashanmugam, Devasena;
- Sato, Paul;
- Siberry, George K.;
- Rexroad, Vivian;
- Valentine, Megan;
- Perlowski, Charlotte;
- Schappell, Elizabeth;
- Thumar, Bhagvinji;
- Luongo, Cindy;
- Barr, Emily;
- Aziz, Mariam;
- Yogev, Ram;
- Spector, Stephen A.;
- Collins, Peter L.;
- McFarland, Elizabeth J.;
- Karron, Ruth A.;
- International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1114 Study Team
Publication type:
journal article
Live-Attenuated Respiratory Syncytial Virus Vaccine Candidate With Deletion of RNA Synthesis Regulatory Protein M2-2 is Highly Immunogenic in Children.
Published in:
2018
By:
- McFarland, Elizabeth J.;
- Karron, Ruth A.;
- Muresan, Petronella;
- Cunningham, Coleen K.;
- Valentine, Megan E.;
- Perlowski, Charlotte;
- Thumar, Bhagvanji;
- Gnanashanmugam, Devasena;
- Siberry, George K.;
- Schappell, Elizabeth;
- Barr, Emily;
- Rexroad, Vivian;
- Yogev, Ram;
- Spector, Stephen A.;
- Aziz, Mariam;
- Patel, Nehali;
- Cielo, Mikhaela;
- Luongo, Cindy;
- Collins, Peter L.;
- Buchholz, Ursula J.
Publication type:
journal article
The alpha-1 subunit of the Na<sup>+</sup>,K<sup>+</sup>-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells.
Published in:
PLoS Pathogens, 2019, v. 15, n. 8, p. 1, doi. 10.1371/journal.ppat.1007963
By:
- Lingemann, Matthias;
- McCarty, Thomas;
- Liu, Xueqiao;
- Buchholz, Ursula J.;
- Surman, Sonja;
- Martin, Scott E.;
- Collins, Peter L.;
- Munir, Shirin
Publication type:
Article
Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus.
Published in:
PLoS Pathogens, 2023, v. 19, n. 9, p. 1, doi. 10.1371/journal.ppat.1011584
By:
- Ou, Li;
- Chen, Steven J.;
- Teng, I-Ting;
- Yang, Lijuan;
- Zhang, Baoshan;
- Zhou, Tongqing;
- Biju, Andrea;
- Cheng, Cheng;
- Kong, Wing-Pui;
- Morano, Nicholas C.;
- Stancofski, Erik-Stephane D.;
- Todd, John-Paul;
- Tsybovsky, Yaroslav;
- Wang, Shuishu;
- Zheng, Cheng-Yan;
- Mascola, John R.;
- Shapiro, Lawrence;
- Woodward, Ruth A.;
- Buchholz, Ursula J.;
- Kwong, Peter D.
Publication type:
Article
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters.
Published in:
PLoS Pathogens, 2023, v. 18, n. 6, p. 1, doi. 10.1371/journal.ppat.1011057
By:
- Liu, Xueqiao;
- Park, Hong-Su;
- Matsuoka, Yumiko;
- Santos, Celia;
- Yang, Lijuan;
- Luongo, Cindy;
- Moore, Ian N.;
- Johnson, Reed F.;
- Garza, Nicole L.;
- Zhang, Peng;
- Lusso, Paolo;
- Best, Sonja M.;
- Buchholz, Ursula J.;
- Le Nouën, Cyril
Publication type:
Article

Found: 38