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Advances in Melanoma-Nevus Classification Using Artificially Generated Image Data Sets.
Published in:
2023
By:
- Brinker, Titus J.
Publication type:
Opinion
Evaluation of Long-term Clearance Rates of Interventions for Actinic Keratosis: A Systematic Review and Network Meta-analysis.
Published in:
2021
By:
- Steeb, Theresa;
- Wessely, Anja;
- Petzold, Anne;
- Brinker, Titus J.;
- Schmitz, Lutz;
- Leiter, Ulrike;
- Garbe, Claus;
- Schöffski, Oliver;
- Berking, Carola;
- Heppt, Markus V.
Publication type:
journal article
Effect of a Face-Aging Mobile App-Based Intervention on Skin Cancer Protection Behavior in Secondary Schools in Brazil: A Cluster-Randomized Clinical Trial.
Published in:
2020
By:
- Brinker, Titus J.;
- Faria, Bianca Lisa;
- de Faria, Olber Moreira;
- Klode, Joachim;
- Schadendorf, Dirk;
- Utikal, Jochen S.;
- Mons, Ute;
- Krieghoff-Henning, Eva;
- Lisboa, Oscar Campos;
- Oliveira, Ana Carla Cruz;
- Lino, Henrique Augusto;
- Bernardes-Souza, Breno
Publication type:
journal article
Facial-Aging App Availability in Waiting Rooms as a Potential Opportunity for Skin Cancer Prevention.
Published in:
2018
By:
- Brinker, Titus J.;
- Klode, Joachim;
- Esser, Stefan;
- Schadendorf, Dirk
Publication type:
Letter
Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer.
Published in:
Journal of Pathology, 2022, v. 256, n. 3, p. 269, doi. 10.1002/path.5831
By:
- Brockmoeller, Scarlet;
- Echle, Amelie;
- Ghaffari Laleh, Narmin;
- Eiholm, Susanne;
- Malmstrøm, Marie Louise;
- Plato Kuhlmann, Tine;
- Levic, Katarina;
- Grabsch, Heike Irmgard;
- West, Nicholas P;
- Saldanha, Oliver Lester;
- Kouvidi, Katerina;
- Bono, Aurora;
- Heij, Lara R;
- Brinker, Titus J;
- Gögenür, Ismayil;
- Quirke, Philip;
- Kather, Jakob Nikolas
Publication type:
Article
Weakly supervised annotation‐free cancer detection and prediction of genotype in routine histopathology.
Published in:
Journal of Pathology, 2022, v. 256, n. 1, p. 50, doi. 10.1002/path.5800
By:
- Schrammen, Peter Leonard;
- Ghaffari Laleh, Narmin;
- Echle, Amelie;
- Truhn, Daniel;
- Schulz, Volkmar;
- Brinker, Titus J;
- Brenner, Hermann;
- Chang‐Claude, Jenny;
- Alwers, Elizabeth;
- Brobeil, Alexander;
- Kloor, Matthias;
- Heij, Lara R;
- Jäger, Dirk;
- Trautwein, Christian;
- Grabsch, Heike I;
- Quirke, Philip;
- West, Nicholas P;
- Hoffmeister, Michael;
- Kather, Jakob Nikolas
Publication type:
Article
Deep learning detects genetic alterations in cancer histology generated by adversarial networks.
Published in:
Journal of Pathology, 2021, v. 254, n. 1, p. 70, doi. 10.1002/path.5638
By:
- Krause, Jeremias;
- Grabsch, Heike I;
- Kloor, Matthias;
- Jendrusch, Michael;
- Echle, Amelie;
- Buelow, Roman David;
- Boor, Peter;
- Luedde, Tom;
- Brinker, Titus J;
- Trautwein, Christian;
- Pearson, Alexander T;
- Quirke, Philip;
- Jenniskens, Josien;
- Offermans, Kelly;
- Brandt, Piet A;
- Kather, Jakob Nikolas
Publication type:
Article
Evaluating deep learning-based melanoma classification using immunohistochemistry and routine histology: A three center study.
Published in:
PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0297146
By:
- Wies, Christoph;
- Schneider, Lucas;
- Haggenmüller, Sarah;
- Bucher, Tabea-Clara;
- Hobelsberger, Sarah;
- Heppt, Markus V.;
- Ferrara, Gerardo;
- Krieghoff-Henning, Eva I.;
- Brinker, Titus J.
Publication type:
Article
Salivary cortisol levels and anxiety in melanoma patients undergoing sentinel lymph node excision under local anesthesia versus general anesthesia: a prospective study.
Published in:
World Journal of Surgical Oncology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12957-020-01823-w
By:
- Jansen, Philipp;
- Stoffels, Ingo;
- Müseler, Anne-Christine;
- Petri, Maximilian;
- Brinker, Titus J.;
- Schedlowski, Manfred;
- Schadendorf, Dirk;
- Engler, Harald;
- Klode, Joachim
Publication type:
Article
The Value of Total Body Photography for the Early Detection of Melanoma: A Systematic Review.
Published in:
International Journal of Environmental Research & Public Health, 2021, v. 18, n. 4, p. 1726, doi. 10.3390/ijerph18041726
By:
- Hornung, Annkathrin;
- Steeb, Theresa;
- Wessely, Anja;
- Brinker, Titus J.;
- Breakell, Thomas;
- Erdmann, Michael;
- Berking, Carola;
- Heppt, Markus V.;
- Tchounwou, Paul B.
Publication type:
Article
Overdiagnosis of melanoma – causes, consequences and solutions.
Published in:
Journal der Deutschen Dermatologischen Gesellschaft, 2020, v. 18, n. 11, p. 1236, doi. 10.1111/ddg.14233
By:
- Kutzner, Heinz;
- Jutzi, Tanja B.;
- Krahl, Dieter;
- Krieghoff‐Henning, Eva I.;
- Heppt, Markus V.;
- Hekler, Achim;
- Schmitt, Max;
- Maron, Roman C. R.;
- Fröhling, Stefan;
- Kalle, Christof;
- Brinker, Titus J.
Publication type:
Article
Überdiagnose von Melanomen – Ursachen, Konsequenzen und Lösungsansätze.
Published in:
Journal der Deutschen Dermatologischen Gesellschaft, 2020, v. 18, n. 11, p. 1236, doi. 10.1111/ddg.14233_g
By:
- Kutzner, Heinz;
- Jutzi, Tanja B.;
- Krahl, Dieter;
- Krieghoff‐Henning, Eva I.;
- Heppt, Markus V.;
- Hekler, Achim;
- Schmitt, Max;
- Maron, Roman C. R.;
- Fröhling, Stefan;
- Kalle, Christof;
- Brinker, Titus J.
Publication type:
Article
Externe wissenschaftliche Evaluation der ersten Teledermatologie-App ohne direkten Patientenkontakt in Deutschland („Online Hautarzt – AppDoc").
Published in:
Der Hautarzt, 2020, v. 71, n. 11, p. 887, doi. 10.1007/s00105-020-04660-w
By:
- Sondermann, Wiebke;
- von Kalle, Christof;
- Utikal, Jochen S.;
- Schadendorf, Dirk;
- Esser, Stefan;
- Durani, Benjamin;
- Durani, Hendrike;
- Jansen, Martin;
- Brinker, Titus J.
Publication type:
Article
Frequent Occurrence of NRAS and BRAF Mutations in Human Acral Naevi.
Published in:
Cancers, 2019, v. 11, n. 4, p. 546, doi. 10.3390/cancers11040546
By:
- Jansen, Philipp;
- Cosgarea, Ioana;
- Murali, Rajmohan;
- Möller, Inga;
- Sucker, Antje;
- Franklin, Cindy;
- Paschen, Annette;
- Zaremba, Anne;
- Brinker, Titus J.;
- Stoffels, Ingo;
- Schadendorf, Dirk;
- Klode, Joachim;
- Hadaschik, Eva;
- Griewank, Klaus G.
Publication type:
Article
Large language model use in clinical oncology.
Published in:
NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00733-4
By:
- Carl, Nicolas;
- Schramm, Franziska;
- Haggenmüller, Sarah;
- Kather, Jakob Nikolas;
- Hetz, Martin J.;
- Wies, Christoph;
- Michel, Maurice Stephan;
- Wessels, Frederik;
- Brinker, Titus J.
Publication type:
Article
Deep learning for dual detection of microsatellite instability and POLE mutations in colorectal cancer histopathology.
Published in:
NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00592-z
By:
- Gustav, Marco;
- Reitsam, Nic Gabriel;
- Carrero, Zunamys I.;
- Loeffler, Chiara M. L.;
- van Treeck, Marko;
- Yuan, Tanwei;
- West, Nicholas P.;
- Quirke, Philip;
- Brinker, Titus J.;
- Brenner, Hermann;
- Favre, Loëtitia;
- Märkl, Bruno;
- Stenzinger, Albrecht;
- Brobeil, Alexander;
- Hoffmeister, Michael;
- Calderaro, Julien;
- Pujals, Anaïs;
- Kather, Jakob Nikolas
Publication type:
Article
Reducing the Impact of Confounding Factors on Skin Cancer Classification via Image Segmentation: Technical Model Study.
Published in:
2021
By:
- Maron, Roman C;
- Hekler, Achim;
- Krieghoff-Henning, Eva;
- Schmitt, Max;
- Schlager, Justin G;
- Utikal, Jochen S;
- Brinker, Titus J
Publication type:
journal article
Artificial Intelligence and Its Effect on Dermatologists' Accuracy in Dermoscopic Melanoma Image Classification: Web-Based Survey Study.
Published in:
2020
By:
- Maron, Roman C;
- Utikal, Jochen S;
- Hekler, Achim;
- Hauschild, Axel;
- Sattler, Elke;
- Sondermann, Wiebke;
- Haferkamp, Sebastian;
- Schilling, Bastian;
- Heppt, Markus V;
- Jansen, Philipp;
- Reinholz, Markus;
- Franklin, Cindy;
- Schmitt, Laurenz;
- Hartmann, Daniela;
- Krieghoff-Henning, Eva;
- Schmitt, Max;
- Weichenthal, Michael;
- Kalle, Christof von;
- Fröhling, Stefan;
- Brinker, Titus J
Publication type:
journal article
Photoaging Mobile Apps: A Novel Opportunity for Smoking Cessation?
Published in:
Journal of Medical Internet Research, 2015, v. 17, n. 7, p. 1, doi. 10.2196/jmir.4792
By:
- Brinker, Titus J.;
- Seeger, Werner
Publication type:
Article
Loss of p53 compensates osteopenia in murine Mysm1 deficiency.
Published in:
FASEB Journal, 2018, v. 32, n. 4, p. 1957, doi. 10.1096/fj.201700871R
By:
- Haffner-Luntzer, Melanie;
- Kovtun, Anna;
- Fischer, Verena;
- Prystaz, Katja;
- Hainzl, Adelheid;
- Kroeger, Carsten M.;
- Krikki, Ioanna;
- Brinker, Titus J.;
- Ignatius, Anita;
- Gatzka, Martina
Publication type:
Article
Assessment of Nonradioactive Multispectral Optoacoustic Tomographic Imaging With Conventional Lymphoscintigraphic Imaging for Sentinel Lymph Node Biopsy in Melanoma.
Published in:
JAMA Network Open, 2019, v. 2, n. 8, p. e199020, doi. 10.1001/jamanetworkopen.2019.9020
By:
- Stoffels, Ingo;
- Jansen, Philipp;
- Petri, Maximilian;
- Goerdt, Lukas;
- Brinker, Titus J.;
- Griewank, Klaus G.;
- Poeppel, Thorsten D.;
- Schadendorf, Dirk;
- Klode, Joachim
Publication type:
Article
Automated curation of large‐scale cancer histopathology image datasets using deep learning.
Published in:
Histopathology, 2024, v. 84, n. 7, p. 1139, doi. 10.1111/his.15159
By:
- Hilgers, Lars;
- Ghaffari Laleh, Narmin;
- West, Nicholas P;
- Westwood, Alice;
- Hewitt, Katherine J;
- Quirke, Philip;
- Grabsch, Heike I;
- Carrero, Zunamys I;
- Matthaei, Emylou;
- Loeffler, Chiara M L;
- Brinker, Titus J;
- Yuan, Tanwei;
- Brenner, Hermann;
- Brobeil, Alexander;
- Hoffmeister, Michael;
- Kather, Jakob Nikolas
Publication type:
Article
A photoaging smartphone application to promote sun safety behaviors among youth in late childhood and adolescence.
Published in:
Pediatric Dermatology, 2024, v. 41, n. 4, p. 641, doi. 10.1111/pde.15618
By:
- Abraham, Jaclyn;
- Natarelli, Nicole;
- Boby, Aleena;
- Wei, Grace;
- Hennessy, Kerry;
- Moore, Sarah;
- Bindernagel, Constance;
- Dabrow, Sharon;
- Soylu, Lana;
- Brinker, Titus J.;
- Seminario‐Vidal, Lucia;
- Albers, Sharon
Publication type:
Article
Deep learning approach to predict lymph node metastasis directly from primary tumour histology in prostate cancer.
Published in:
BJU International, 2021, v. 128, n. 3, p. 352, doi. 10.1111/bju.15386
By:
- Wessels, Frederik;
- Schmitt, Max;
- Krieghoff‐Henning, Eva;
- Jutzi, Tanja;
- Worst, Thomas S.;
- Waldbillig, Frank;
- Neuberger, Manuel;
- Maron, Roman C.;
- Steeg, Matthias;
- Gaiser, Timo;
- Hekler, Achim;
- Utikal, Jochen S.;
- von Kalle, Christof;
- Fröhling, Stefan;
- Michel, Maurice S.;
- Nuhn, Philipp;
- Brinker, Titus J.
Publication type:
Article
A Face-Aging Smoking Prevention/Cessation Intervention for Nursery School Students in Germany: An Appearance-Focused Interventional Study.
Published in:
International Journal of Environmental Research & Public Health, 2018, v. 15, n. 8, p. 1656, doi. 10.3390/ijerph15081656
By:
- Brinker, Titus J.;
- Alfitian, Jonas;
- Seeger, Werner;
- Groneberg, David A.;
- von Kalle, Christof;
- Enk, Alexander H.;
- Herth, Felix J. F.;
- Kreuter, Michael;
- Bauer, Claudia M.;
- Gatzka, Martina;
- Suhre, Janina L.
Publication type:
Article
A self-supervised vision transformer to predict survival from histopathology in renal cell carcinoma.
Published in:
World Journal of Urology, 2023, v. 41, n. 8, p. 2233, doi. 10.1007/s00345-023-04489-7
By:
- Wessels, Frederik;
- Schmitt, Max;
- Krieghoff-Henning, Eva;
- Nientiedt, Malin;
- Waldbillig, Frank;
- Neuberger, Manuel;
- Kriegmair, Maximilian C.;
- Kowalewski, Karl-Friedrich;
- Worst, Thomas S.;
- Steeg, Matthias;
- Popovic, Zoran V.;
- Gaiser, Timo;
- von Kalle, Christof;
- Utikal, Jochen S.;
- Fröhling, Stefan;
- Michel, Maurice S.;
- Nuhn, Philipp;
- Brinker, Titus J.
Publication type:
Article
Colorectal cancer risk stratification on histological slides based on survival curves predicted by deep learning.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00451-3
By:
- Höhn, Julia;
- Krieghoff-Henning, Eva;
- Wies, Christoph;
- Kiehl, Lennard;
- Hetz, Martin J.;
- Bucher, Tabea-Clara;
- Jonnagaddala, Jitendra;
- Zatloukal, Kurt;
- Müller, Heimo;
- Plass, Markus;
- Jungwirth, Emilian;
- Gaiser, Timo;
- Steeg, Matthias;
- Holland-Letz, Tim;
- Brenner, Hermann;
- Hoffmeister, Michael;
- Brinker, Titus J.
Publication type:
Article
Robust and accurate quantification of biomarkers of immune cells in lung cancer micro-environment using deep convolutional neural networks.
Published in:
PeerJ, 2019, p. 1, doi. 10.7717/peerj.6335
By:
- Aprupe, Lilija;
- Litjens, Geert;
- Brinker, Titus J.;
- van der Laak, Jeroen;
- Grabe, Niels
Publication type:
Article
Deep learning can predict survival directly from histology in clear cell renal cell carcinoma.
Published in:
PLoS ONE, 2022, v. 17, n. 8, p. 1, doi. 10.1371/journal.pone.0272656
By:
- Wessels, Frederik;
- Schmitt, Max;
- Krieghoff-Henning, Eva;
- Kather, Jakob N.;
- Nientiedt, Malin;
- Kriegmair, Maximilian C.;
- Worst, Thomas S.;
- Neuberger, Manuel;
- Steeg, Matthias;
- Popovic, Zoran V.;
- Gaiser, Timo;
- von Kalle, Christof;
- Utikal, Jochen S.;
- Fröhling, Stefan;
- Michel, Maurice S.;
- Nuhn, Philipp;
- Brinker, Titus J.
Publication type:
Article
Time-updated resting heart rate predicts mortality in patients with COPD.
Published in:
Clinical Research in Cardiology, 2020, v. 109, n. 6, p. 776, doi. 10.1007/s00392-019-01572-1
By:
- Omlor, Albert J.;
- Trudzinski, Franziska C.;
- Alqudrah, Mohamad;
- Seiler, Frederik;
- Biertz, Frank;
- Vogelmeier, Claus F.;
- Welte, Tobias;
- Watz, Henrik;
- Waschki, Benjamin;
- Brinker, Titus J.;
- Andreas, Stefan;
- Fähndrich, Sebastian;
- Alter, Peter;
- Jörres, Rudolf A.;
- Böhm, Michael;
- Bals, Robert
Publication type:
Article
Artificial intelligence to predict oncological outcome directly from hematoxylin and eosin-stained slides in urology.
Published in:
Minerva Urology & Nephrology, 2022, v. 74, n. 5, p. 538, doi. 10.23736/S2724-6051.22.04758-9
By:
- WESSELS, Frederik;
- KUNTZ, Sara;
- KRIEGHOFF-HENNING, Eva;
- SCHMITT, Max;
- BRAUN, Volker;
- WORST, Thomas S.;
- NEUBERGER, Manuel;
- STEEG, Matthias;
- GAISER, Timo;
- FRÖHLING, Stefan;
- MICHEL, Maurice-Stephan;
- NUHN, Philipp;
- BRINKER, Titus J.
Publication type:
Article
Reply to: False conflict and false confirmation errors are crucial components of AI accuracy in medical decision making.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50954-1
By:
- Wies, Christoph;
- Hauser, Katja;
- Brinker, Titus J.
Publication type:
Article
Enhanced classifier training to improve precision of a convolutional neural network to identify images of skin lesions.
Published in:
PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218713
By:
- Brinker, Titus J.;
- Hekler, Achim;
- Enk, Alexander H.;
- von Kalle, Christof
Publication type:
Article
The "Intimarzt" (intimate doctor) Model Project: Anonymous Remote Diagnosis of Sexually Transmitted Diseases.
Published in:
Deutsches Ärzteblatt International, 2023, v. 120, n. 6, p. 94, doi. 10.3238/arztebl.m2022.0350
By:
- Sondermann, Wiebke;
- Wies, Christoph;
- Esser, Stefan;
- Utikal, Jochen S.;
- Schadendorf, Dirk;
- Brinker, Titus J.
Publication type:
Article
Primary leiomyosarcoma of the skin: a comprehensive review on diagnosis and treatment.
Published in:
2018
By:
- Zacher, Martina;
- Heppt, Markus V.;
- Brinker, Titus J.;
- Hayani, Kinan M.;
- Flaig, Michael J.;
- Berking, Carola
Publication type:
journal article

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