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Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.
- Published in:
- Angewandte Chemie, 2017, v. 129, n. 21, p. 5832, doi. 10.1002/ange.201611281
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- Publication type:
- Article
Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 21, p. 5738, doi. 10.1002/anie.201611281
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- Publication type:
- Article
A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas.
- Published in:
- 2013
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- Publication type:
- journal article
A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas.
- Published in:
- Journal of Clinical Investigation, 2013, v. 123, n. 11, p. 4612, doi. 10.1172/JCI64210
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- Publication type:
- Article
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.
- Published in:
- 2010
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- Publication type:
- journal article
MELK is not necessary for the proliferation of basal-like breast cancer cells.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.26693
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- Publication type:
- Article
Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 16, p. 7790, doi. 10.1093/nar/gkv645
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- Publication type:
- Article
Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies.
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- Nucleic Acids Research, 2015, v. 43, n. 12, p. 5880, doi. 10.1093/nar/gkv262
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- Publication type:
- Article
Acetylation site specificities of lysine deacetylase inhibitors in human cells.
- Published in:
- Nature Biotechnology, 2015, v. 33, n. 4, p. 415, doi. 10.1038/nbt.3130
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- Publication type:
- Article
Genome-wide localization of small molecules.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 1, p. 92, doi. 10.1038/nbt.2776
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- Publication type:
- Article
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
- Published in:
- Nature Medicine, 2015, v. 21, n. 4, p. 335, doi. 10.1038/nm.3832
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- Publication type:
- Article
Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease.
- Published in:
- Nature Genetics, 2009, v. 41, n. 12, p. 1341, doi. 10.1038/ng.490
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- Publication type:
- Article
Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells.
- Published in:
- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0126328
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- Publication type:
- Article
Regulation of <i>MYC</i> Expression and Differential JQ1 Sensitivity in Cancer Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087003
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- Publication type:
- Article
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11672-1
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- Publication type:
- Article
Direct inhibition of the NOTCH transcription factor complex.
- Published in:
- 2010
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- Publication type:
- Correction Notice
Direct inhibition of the NOTCH transcription factor complex.
- Published in:
- Nature, 2009, v. 462, n. 7270, p. 182, doi. 10.1038/nature08543
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- Publication type:
- Article
HDAC2 negatively regulates memory formation and synaptic plasticity.
- Published in:
- Nature, 2009, v. 459, n. 7243, p. 55, doi. 10.1038/nature07925
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- Publication type:
- Article
BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.
- Published in:
- Cancer Medicine, 2016, v. 5, n. 6, p. 1183, doi. 10.1002/cam4.667
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- Publication type:
- Article
Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome.
- Published in:
- Nature Communications, 2017, v. 8, n. 2, p. 14400, doi. 10.1038/ncomms14400
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- Publication type:
- Article
Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle.
- Published in:
- Nature Communications, 2014, v. 5, n. 3, p. 3511, doi. 10.1038/ncomms4511
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- Publication type:
- Article
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase.
- Published in:
- Science Translational Medicine, 2017, v. 9, n. 398, p. 1, doi. 10.1126/scitranslmed.aal5272
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- Publication type:
- Article
BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.
- Published in:
- Science Translational Medicine, 2017, v. 9, n. 390, p. 1, doi. 10.1126/scitranslmed.aah5084
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- Publication type:
- Article
Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 14, p. 3982, doi. 10.1093/hmg/ddv136
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- Publication type:
- Article
Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma.
- Published in:
- International Journal of Cancer, 2015, v. 136, n. 9, p. 2055, doi. 10.1002/ijc.29269
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- Publication type:
- Article
Erratum: Notch inhibition allows oncogene-independent generation of iPS cells.
- Published in:
- Nature Chemical Biology, 2014, v. 10, n. 12, p. 1074, doi. 10.1038/nchembio1214-1074b
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- Publication type:
- Article
Erratum: Notch inhibition allows oncogene-independent generation of iPS cells.
- Published in:
- Nature Chemical Biology, 2014, v. 10, n. 12, p. 1074, doi. 10.1038/nchembio1214-1074c
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- Publication type:
- Article
Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.
- Published in:
- PLoS Pathogens, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.ppat.1006668
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- Publication type:
- Article
The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.
- Published in:
- Journal of Cellular Physiology, 2015, v. 230, n. 11, p. 2683, doi. 10.1002/jcp.24991
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- Publication type:
- Article
Cancer: An essential passenger with p53.
- Published in:
- Nature, 2015, v. 520, n. 7549, p. 626, doi. 10.1038/nature14390
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- Publication type:
- Article
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
- Published in:
- Nature, 2011, v. 478, n. 7370, p. 524, doi. 10.1038/nature10334
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- Publication type:
- Article
Intensive treatment and survival outcomes in NUT midline carcinoma of the head and neck.
- Published in:
- 2016
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- Publication type:
- journal article
Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET.
- Published in:
- ChemMedChem, 2016, v. 11, n. 23, p. 2575, doi. 10.1002/cmdc.201600502
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- Publication type:
- Article
Back Cover: Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET (ChemMedChem 23/2016).
- Published in:
- ChemMedChem, 2016, v. 11, n. 23, p. 2638, doi. 10.1002/cmdc.201600587
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- Publication type:
- Article
Notch inhibition allows oncogene-independent generation of iPS cells.
- Published in:
- Nature Chemical Biology, 2014, v. 10, n. 8, p. 632, doi. 10.1038/nchembio.1552
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- Publication type:
- Article
Chemical phylogenetics of histone deacetylases.
- Published in:
- Nature Chemical Biology, 2010, v. 6, n. 3, p. 238, doi. 10.1038/nchembio.313
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- Publication type:
- Article
A pulse at the heart of targeted therapy.
- Published in:
- Nature Chemical Biology, 2009, v. 5, n. 3, p. 144, doi. 10.1038/nchembio0309-144
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- Publication type:
- Article
DNA-bend modulation in a repressor-to-activator switching mechanism.
- Published in:
- Nature, 1995, v. 374, n. 6520, p. 371, doi. 10.1038/374370a0
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- Publication type:
- Article
In Vivo Pharmacodynamic Imaging of Proteasome Inhibition.
- Published in:
- Molecular Imaging, 2009, v. 8, n. 3, p. 140, doi. 10.2310/7290.2009.00007
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- Publication type:
- Article
Synthesis and Biochemical Evaluation of Biotinylated Conjugates of Largazole Analogues: Selective Class I Histone Deacetylase Inhibitors.
- Published in:
- Israel Journal of Chemistry, 2017, v. 57, n. 3/4, p. 319, doi. 10.1002/ijch.201600130
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- Publication type:
- Article
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18377-w
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- Publication type:
- Article
Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16103-0
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- Publication type:
- Article
Fluorous-Based Small-Molecule Microarrays for the Discovery of Histone Deacetylase Inhibitors.
- Published in:
- Angewandte Chemie International Edition, 2007, v. 46, n. 42, p. 7960, doi. 10.1002/anie.200703198
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- Publication type:
- Article