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The Conformation of the Prion Domain of Sup35 p in Isolation and in the Full-Length Protein.
- Published in:
- Angewandte Chemie International Edition, 2013, v. 52, n. 48, p. 12741, doi. 10.1002/anie.201304699
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- Publication type:
- Article
The yeast prion Ure2p retains its native α‐helical conformation upon assembly into protein fibrils in vitro.
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- EMBO Journal, 2002, v. 21, n. 12, p. 2903, doi. 10.1093/emboj/cdf303
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- Publication type:
- Article
The yeast prion Ure2p retains its native a-helical conformation upon assembly into protein fibrils in vitro.
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- EMBO Journal, 2002, v. 21, n. 12, p. 2903, doi. 10.1093/emboj/cdf303
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- Publication type:
- Article
Crucial Role of FABP3 in αSyn-Induced Reduction of Septal GABAergic Neurons and Cognitive Decline in Mice.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 400, doi. 10.3390/ijms22010400
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- Publication type:
- Article
Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5358, doi. 10.3390/ijms20215358
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- Article
Alpha-synuclein transfers from neurons to oligodendrocytes.
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- Glia, 2014, v. 62, n. 3, p. 387, doi. 10.1002/glia.22611
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- Article
β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors.
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- Glia, 2013, v. 61, n. 10, p. 1673, doi. 10.1002/glia.22548
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- Publication type:
- Article
Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neurons.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23682-z
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- Publication type:
- Article
TAU SPREADING: HOW ARE TAU ASSEMBLIES TRANSFERRED FROM CELL TO CELL?
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P906, doi. 10.1016/j.jalz.2017.07.320
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- Publication type:
- Article
Die Konformation der Prionendomäne von Sup35: isoliert und im Kontext des Volllängen-Proteins.
- Published in:
- Angewandte Chemie, 2013, v. 125, n. 48, p. 12974, doi. 10.1002/ange.201304699
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- Publication type:
- Article
A Native-Like Conformation for the C-Terminal Domain of the Prion Ure2p within its Fibrillar Form.
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- Angewandte Chemie, 2012, v. 124, n. 32, p. 8087, doi. 10.1002/ange.201202093
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- Publication type:
- Article
Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies.
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0386-4
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- Publication type:
- Article
Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA.
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- Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/2051-5960-2-29
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- Publication type:
- Article
The role of Galectin-3 in α-synuclein-induced microglial activation.
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- Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0156-0
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- Publication type:
- Article
Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein.
- Published in:
- Scientific Reports, 2016, p. 37970, doi. 10.1038/srep37970
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- Article
α-Synuclein and huntingtin exon 1 amyloid fibrils bind laterally to the cellular membrane.
- Published in:
- Scientific Reports, 2016, p. 19180, doi. 10.1038/srep19180
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- Publication type:
- Article
Peripheral Inflammation Regulates CNS Immune Surveillance Through the Recruitment of Inflammatory Monocytes Upon Systemic α-Synuclein Administration.
- Published in:
- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00080
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- Publication type:
- Article
A mutation within the C-terminal domain of Sup35p that affects [ PSI<sup>+</sup>] prion propagation.
- Published in:
- Molecular Microbiology, 2011, v. 81, n. 3, p. 640, doi. 10.1111/j.1365-2958.2011.07719.x
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- Publication type:
- Article
Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein.
- Published in:
- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100760
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- Publication type:
- Article
Unlike Twins: An NMR Comparison of Two α-Synuclein Polymorphs Featuring Different Toxicity.
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- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090659
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- Publication type:
- Article
Structure and Assembly Properties of the N-Terminal Domain of the Prion Ure2p in Isolation and in Its Natural Context.
- Published in:
- PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009760
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- Publication type:
- Article
CONFINE-MAS: a magic-angle spinning NMR probe that confines the sample in case of a rotor explosion.
- Published in:
- Journal of Biomolecular NMR, 2018, v. 72, n. 3/4, p. 171, doi. 10.1007/s10858-018-0218-x
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- Publication type:
- Article
Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion.
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- Journal of Biomolecular NMR, 2011, v. 51, n. 3, p. 235, doi. 10.1007/s10858-011-9530-4
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- Publication type:
- Article
α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. 1, doi. 10.1186/s40478-019-0859-3
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- Publication type:
- Article
Neurons with Cat's Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 3, p. 436, doi. 10.3390/biom12030436
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- Article
The prion-like domain of Drosophila Imp promotes axonal transport of RNP granules in vivo.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10554-w
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- Publication type:
- Article
Clustering of Tau fibrils impairs the synaptic composition of α3‐Na<sup>+</sup>/K<sup>+</sup>‐ATPase and AMPA receptors.
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- EMBO Journal, 2019, v. 38, n. 3, p. N.PAG, doi. 10.15252/embj.201899871
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- Publication type:
- Article
Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes.
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- EMBO Journal, 2016, v. 35, n. 19, p. 2120, doi. 10.15252/embj.201593411
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- Publication type:
- Article
α-synuclein assemblies sequester neuronal α3-Na<sup>+</sup>/K<sup>+</sup>- ATPase and impair Na<sup>+</sup> gradient.
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- EMBO Journal, 2015, v. 34, n. 19, p. 2408, doi. 10.15252/embj.201591397
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- Publication type:
- Article
C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons.
- Published in:
- Life Science Alliance, 2022, v. 5, n. 9, p. 1, doi. 10.26508/lsa.202101276
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- Publication type:
- Article
Long term worsening of amyloid pathology, cerebral function, and cognition after a single inoculation of beta-amyloid seeds with Osaka mutation.
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- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01559-0
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- Publication type:
- Article
The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61757-x
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- Publication type:
- Article
Synapses do not facilitate prion-like transfer of alpha-synuclein: a quantitative study in reconstructed unidirectional neural networks.
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- Cellular & Molecular Life Sciences, 2023, v. 80, n. 10, p. 1, doi. 10.1007/s00018-023-04915-4
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- Publication type:
- Article
Structural and functional characterization of two alpha-synuclein strains.
- Published in:
- Nature Communications, 2013, v. 4, n. 10, p. 2575, doi. 10.1038/ncomms3575
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- Publication type:
- Article
Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease.
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- 2019
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- Publication type:
- journal article
G51D [alpha]-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome.
- Published in:
- 2013
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- Publication type:
- Journal Article
G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome.
- Published in:
- Annals of Neurology, 2013, v. 73, n. 4, p. 459, doi. 10.1002/ana.23894
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- Publication type:
- Article
Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport.
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- 2012
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- Publication type:
- journal article
Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport.
- Published in:
- Annals of Neurology, 2012, v. 72, n. 4, p. 517, doi. 10.1002/ana.23747
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- Publication type:
- Article
Distinct alpha‐Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH‐SY5Y cells.
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- Journal of Neurochemistry, 2021, v. 156, n. 6, p. 880, doi. 10.1111/jnc.15174
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- Article
α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities.
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- Journal of Neurochemistry, 2019, v. 150, n. 5, p. 522, doi. 10.1111/jnc.14808
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- Publication type:
- Article
Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis.
- Published in:
- Cell Death & Disease, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41419-020-03369-x
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- Publication type:
- Article
The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies.
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- Acta Neuropathologica, 2020, v. 139, n. 6, p. 977, doi. 10.1007/s00401-020-02157-3
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- Publication type:
- Article
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons.
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- Acta Neuropathologica, 2019, v. 137, n. 6, p. 961, doi. 10.1007/s00401-019-01995-0
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- Publication type:
- Article
Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms.
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- Acta Neuropathologica, 2019, v. 137, n. 6, p. 981, doi. 10.1007/s00401-019-01973-6
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- Publication type:
- Article
α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading.
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- Acta Neuropathologica, 2017, v. 134, n. 5, p. 789, doi. 10.1007/s00401-017-1746-2
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- Publication type:
- Article
Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.
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- Acta Neuropathologica, 2017, v. 134, n. 4, p. 629, doi. 10.1007/s00401-017-1722-x
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- Publication type:
- Article
Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1.
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- Acta Neuropathologica, 2016, v. 131, n. 4, p. 539, doi. 10.1007/s00401-016-1538-0
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- Article
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.
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- Acta Neuropathologica, 2014, v. 128, n. 6, p. 805, doi. 10.1007/s00401-014-1343-6
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- Publication type:
- Article
Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice.
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- Acta Neuropathologica, 2013, v. 126, n. 4, p. 555, doi. 10.1007/s00401-013-1160-3
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- Publication type:
- Article