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FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.
- Published in:
- EMBO Journal, 2004, v. 23, n. 24, p. 4802, doi. 10.1038/sj.emboj.7600476
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- Publication type:
- Article
Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38.
- Published in:
- EMBO Journal, 2002, v. 21, n. 14, p. 3782, doi. 10.1093/emboj/cdf361
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- Publication type:
- Article
All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.
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- EMBO Journal, 1998, v. 17, n. 23, p. 6776, doi. 10.1093/emboj/17.23.6776
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- Publication type:
- Article
Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling.
- Published in:
- EMBO Journal, 1998, v. 17, n. 20, p. 5905, doi. 10.1093/emboj/17.20.5905
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- Publication type:
- Article
Stimulation of gene induction and cell growth by the Ras effector Rlf.
- Published in:
- EMBO Journal, 1997, v. 16, n. 22, p. 6748, doi. 10.1093/emboj/16.22.6748
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- Publication type:
- Article
Rapid Ca<sup>2+</sup>-mediated activation of Rap1 in human platelets.
- Published in:
- EMBO Journal, 1997, v. 16, n. 2, p. 252, doi. 10.1093/emboj/16.2.252
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- Publication type:
- Article
Specificity of commonly used cyclic nucleotides with PKA, PKG and Epac-implementing microcalorimetry to determine PDE activities.
- Published in:
- 2007
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- Publication type:
- Abstract
Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator.
- Published in:
- EMBO Reports, 2004, v. 5, n. 12, p. 1176, doi. 10.1038/sj.embor.7400290
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- Publication type:
- Article
Molecular mechanisms in signal transduction and cancer.
- Published in:
- 2004
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- Publication type:
- Interview
cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic β cells and rat INS-1 cells.
- Published in:
- Journal of Physiology, 2006, v. 573, n. 3, p. 595, doi. 10.1113/jphysiol.2006.107391
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- Publication type:
- Article
Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.18489
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- Publication type:
- Article
Cyclic nucleotide analogs as probes of signaling pathways.
- Published in:
- 2008
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- Publication type:
- Letter
DEP domains: structurally similar but functionally different.
- Published in:
- Nature Reviews Molecular Cell Biology, 2014, v. 15, n. 5, p. 357, doi. 10.1038/nrm3791
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- Publication type:
- Article
Capturing cyclic nucleotides in action: snapshots from crystallographic studies.
- Published in:
- Nature Reviews Molecular Cell Biology, 2007, v. 8, n. 1, p. 63, doi. 10.1038/nrm2082
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- Publication type:
- Article
Opinion: Epac: a new cAMP target and new avenues in cAMP research.
- Published in:
- Nature Reviews Molecular Cell Biology, 2003, v. 4, n. 9, p. 733, doi. 10.1038/nrm1197
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- Publication type:
- Article
RAP1 SIGNALLING: ADHERING TO NEW MODELS.
- Published in:
- Nature Reviews Molecular Cell Biology, 2001, v. 2, n. 5, p. 369, doi. 10.1038/35073073
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- Publication type:
- Article
Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β[sub 2]-adrenergic receptor.
- Published in:
- Journal of Cell Biology, 2003, v. 160, n. 4, p. 487, doi. 10.1083/jcb.200209105
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- Publication type:
- Article
Mechanisms of Isoform Specific Rap2 Signaling during Enterocytic Brush Border Formation.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106687
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- Publication type:
- Article
The PDZ Domain of the Guanine Nucleotide Exchange Factor PDZGEF Directs Binding to Phosphatidic Acid during Brush Border Formation.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098253
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- Publication type:
- Article
Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance.
- Published in:
- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057903
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- Publication type:
- Article
Rap1 Can Bypass the FAK-Src-Paxillin Cascade to Induce Cell Spreading and Focal Adhesion Formation.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050072
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- Publication type:
- Article
RAS gene mutations in childhood acute myeloid leukemia: A pediatric oncology group study.
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- Genes, Chromosomes & Cancer, 1990, v. 2, n. 2, p. 159, doi. 10.1002/gcc.2870020212
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- Publication type:
- Article
Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia.
- Published in:
- Nature, 1985, v. 315, n. 6022, p. 726, doi. 10.1038/315726a0
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- Publication type:
- Article
Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP.
- Published in:
- Oncogene, 2005, v. 24, n. 12, p. 2087, doi. 10.1038/sj.onc.1208450
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- Publication type:
- Article
RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans.
- Published in:
- EMBO Journal, 2007, v. 26, n. 24, p. 5083, doi. 10.1038/sj.emboj.7601922
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- Publication type:
- Article
Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B.
- Published in:
- Nature, 2008, v. 455, n. 7209, p. 124, doi. 10.1038/nature07187
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- Publication type:
- Article
Rap2A links intestinal cell polarity to brush border formation.
- Published in:
- Nature Cell Biology, 2012, v. 14, n. 8, p. 793, doi. 10.1038/ncb2537
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- Publication type:
- Article
TSPYL5 suppresses p53 levels and function by physical interaction with USP7.
- Published in:
- Nature Cell Biology, 2011, v. 13, n. 1, p. 102, doi. 10.1038/ncb2142
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- Publication type:
- Article
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 11, p. 901, doi. 10.1038/ncb874
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- Publication type:
- Article
Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and ΔE1B adenovirus replication in human cells.
- Published in:
- Oncogene, 1999, v. 18, n. 36, p. 5032, doi. 10.1038/sj.onc.1202886
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- Publication type:
- Article
Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells.
- Published in:
- Oncogene, 1999, v. 18, n. 31, p. 4435, doi. 10.1038/sj.onc.1202834
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- Publication type:
- Article
The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells.
- Published in:
- Oncogene, 1998, v. 16, n. 3, p. 349, doi. 10.1038/sj.onc.1201540
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- Publication type:
- Article
Insulin activates Stat3 independently of p21ras-ERK and PI-3K signal transduction.
- Published in:
- Oncogene, 1997, v. 15, n. 21, p. 2529, doi. 10.1038/sj.onc.1201429
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- Publication type:
- Article
Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation.
- Published in:
- Oncogene, 1997, v. 14, n. 10, p. 1147, doi. 10.1038/sj.onc.1200911
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- Publication type:
- Article
Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.
- Published in:
- Oncogene, 1997, v. 14, n. 5, p. 623, doi. 10.1038/sj.onc.1201005
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- Publication type:
- Article
Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome.
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- FASEB Journal, 2013, v. 27, n. 10, p. 4122, doi. 10.1096/fj.13-230433
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- Publication type:
- Article
RAPL: taking the Rap in immunity.
- Published in:
- Nature Immunology, 2004, v. 5, n. 10, p. 1007, doi. 10.1038/ni1004-1007
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- Publication type:
- Article
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state.
- Published in:
- Nature, 2006, v. 439, n. 7076, p. 625, doi. 10.1038/nature04468
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- Publication type:
- Article
Signal transduction: Thumbs up for inactivation.
- Published in:
- Nature, 2004, v. 429, n. 6988, p. 138, doi. 10.1038/429138a
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- Publication type:
- Article
Forkhead transcriptions factor FOXO3a protects quiescent cells from oxidative stress.
- Published in:
- Nature, 2002, v. 419, n. 6904, p. 316, doi. 10.1038/nature01036
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- Publication type:
- Article
Glowing switches.
- Published in:
- Nature, 2001, v. 411, n. 6841, p. 1006, doi. 10.1038/35082667
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- Publication type:
- Article
The Benefits and Costs of JTPA Title II-A programs. Key Findings from the National Job Training Partnership Act Study.
- Published in:
- Journal of Human Resources, 1997, v. 32, n. 3, p. 549, doi. 10.2307/146183
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- Publication type:
- Article
The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.
- Published in:
- Journal of Cell Biology, 2011, v. 193, n. 6, p. 1009, doi. 10.1083/jcb.201011126
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- Publication type:
- Article
Unilateral and Multilateral Congenital Coronary-Pulmonary Fistulas in Adults: Clinical Presentation, Diagnostic Modalities, and Management With a Brief Review of the Literature.
- Published in:
- Clinical Cardiology, 2014, v. 37, n. 9, p. 536, doi. 10.1002/clc.22297
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- Publication type:
- Article
Ras Oncogene Mutations in Basal Cell Carcinomas and Squamous Cell Carcinomas of Human Skin.
- Published in:
- Journal of Investigative Dermatology, 1990, v. 94, n. 4, p. 423, doi. 10.1111/1523-1747.ep12874504
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- Publication type:
- Article
Structure-Guided Design of Selective Epac1 and Epac2 Agonists.
- Published in:
- PLoS Biology, 2015, v. 13, n. 1, p. 1, doi. 10.1371/journal.pbio.1002038
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- Publication type:
- Article
Structure and regulation of the cAMP-binding domains of Epac2.
- Published in:
- Nature Structural Biology, 2003, v. 10, n. 1, p. 26, doi. 10.1038/nsb878
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- Publication type:
- Article
A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization.
- Published in:
- PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0207159
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- Publication type:
- Article
Epac1 regulates integrity of endothelial cell junctions through VE-cadherin
- Published in:
- FEBS Letters, 2005, v. 579, n. 22, p. 4966, doi. 10.1016/j.febslet.2005.07.080
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- Publication type:
- Article
Using a Regression Discontinuity Design to Estimate the Impact of Placement Decisions in Developmental Math.
- Published in:
- Research in Higher Education, 2016, v. 57, n. 2, p. 123, doi. 10.1007/s11162-015-9382-y
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- Publication type:
- Article