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Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells.
Published in:
Cellular Microbiology, 2011, v. 13, n. 3, p. 432, doi. 10.1111/j.1462-5822.2010.01546.x
By:
- Schaar, Viveka;
- de Vries, Stefan P. W.;
- Perez Vidakovics, Maria Laura A.;
- Bootsma, Hester J.;
- Larsson, Lennart;
- Hermans, Peter W. M.;
- Bjartell, Anders;
- Mörgelin, Matthias;
- Riesbeck, Kristian
Publication type:
Article
Analysis of Moraxella catarrhalis by DNA Typing: Evidence for a Distinct Subpopulation Associated with Virulence Traits.
Published in:
Journal of Infectious Diseases, 2000, v. 181, n. 4
By:
- Bootsma, Hester J.;
- van der Heide, Han G.J.;
- van der Pas, Simone;
- Schouls, Leo M.;
- Mooi, Frits R.
Publication type:
Article
Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries.
Published in:
2018
By:
- Yahiaoui, Rachid Y.;
- Bootsma, Hester J.;
- den Heijer, Casper D. J.;
- Pluister, Gerlinde N.;
- John Paget, W.;
- Spreeuwenberg, Peter;
- Trzcinski, Krzysztof;
- Stobberingh, Ellen E.
Publication type:
journal article
The global nutritional regulator CodY is an essential protein in the human pathogen Streptococcus pneumoniae.
Published in:
Molecular Microbiology, 2010, v. 78, n. 2, p. 344, doi. 10.1111/j.1365-2958.2010.07339.x
By:
- Caymaris, Stéphanie;
- Bootsma, Hester J.;
- Martin, Bernard;
- Hermans, Peter W. M.;
- Prudhomme, Marc;
- Claverys, Jean-Pierre
Publication type:
Article
Diversity in the Bordetella virulence regulon: transcriptional control of a Bvg-intermediate phase gene.
Published in:
Molecular Microbiology, 2001, v. 40, n. 3, p. 669, doi. 10.1046/j.1365-2958.2001.02415.x
By:
- Deora, Rajendar;
- Bootsma, Hester J.;
- Miller, Jeff F.;
- Cotter, Peggy A.
Publication type:
Article
Genesis of BRO β-lactamase-producing Moraxella catarrhalis: evidence for transformation-mediated horizontal transfer.
Published in:
Molecular Microbiology, 2000, v. 36, n. 1, p. 93, doi. 10.1046/j.1365-2958.2000.01828.x
By:
- Bootsma, Hester J.;
- van Dijk, Hans;
- Vauterin, Paul;
- Verhoef, Jan;
- Mooi, Frits R.
Publication type:
Article
Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.
Published in:
PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145138
By:
- Hommes, Tijmen J.;
- van Lieshout, Miriam H.;
- van ‘t Veer, Cornelis;
- Florquin, Sandrine;
- Bootsma, Hester J.;
- Hermans, Peter W.;
- de Vos, Alex F.;
- van der Poll, Tom
Publication type:
Article
Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123702
By:
- Johnston, Calum;
- Bootsma, Hester J.;
- Aldridge, Christine;
- Manuse, Sylvie;
- Gisch, Nicolas;
- Schwudke, Dominik;
- Hermans, Peter W. M.;
- Grangeasse, Christophe;
- Polard, Patrice;
- Vollmer, Waldemar;
- Claverys, Jean-Pierre
Publication type:
Article
The Carbapenem Inactivation Method (CIM), a Simple and Low-Cost Alternative for the Carba NP Test to Assess Phenotypic Carbapenemase Activity in Gram-Negative Rods.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0123690
By:
- van der Zwaluw, Kim;
- de Haan, Angela;
- Pluister, Gerlinde N.;
- Bootsma, Hester J.;
- de Neeling, Albert J.;
- Schouls, Leo M.
Publication type:
Article
The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice.
Published in:
PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118181
By:
- de Vos, Alex F.;
- Dessing, Mark C.;
- Lammers, Adriana J. J.;
- de Porto, Alexander P. N. A.;
- Florquin, Sandrine;
- de Boer, Onno J.;
- de Beer, Regina;
- Terpstra, Sanne;
- Bootsma, Hester J.;
- Hermans, Peter W.;
- van ‘t Veer, Cornelis;
- van der Poll, Tom
Publication type:
Article
Genome-Wide Identification of Genes Essential for the Survival of Streptococcus pneumoniae in Human Saliva.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089541
By:
- Verhagen, Lilly M.;
- de Jonge, Marien I.;
- Burghout, Peter;
- Schraa, Kiki;
- Spagnuolo, Lorenza;
- Mennens, Svenja;
- Eleveld, Marc J.;
- van der Gaast-de Jongh, Christa E.;
- Zomer, Aldert;
- Hermans, Peter W. M.;
- Bootsma, Hester J.
Publication type:
Article
Differentially Expressed Genes in Bordetella pertussis Strains Belonging to a Lineage Which Recently Spread Globally.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084523
By:
- Gouw, Daan de;
- Hermans, Peter W. M.;
- Bootsma, Hester J.;
- Zomer, Aldert;
- Heuvelman, Kees;
- Diavatopoulos, Dimitri A.;
- Mooi, Frits R.
Publication type:
Article
Streptococcus pneumoniae Serine Protease HtrA, but Not SFP or PrtA, Is a Major Virulence Factor in Pneumonia.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080062
By:
- de Stoppelaar, Sacha F.;
- Bootsma, Hester J.;
- Zomer, Aldert;
- Roelofs, Joris J. T. H.;
- Hermans, Peter W. M.;
- van ’t Veer, Cornelis;
- van der Poll, Tom
Publication type:
Article
Characterization of the Molecular Interplay between Moraxella catarrhalis and Human Respiratory Tract Epithelial Cells.
Published in:
PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072193
By:
- de Vries, Stefan P. W.;
- Eleveld, Marc J.;
- Hermans, Peter W. M.;
- Bootsma, Hester J.
Publication type:
Article
ESSENTIALS: Software for Rapid Analysis of High Throughput Transposon Insertion Sequencing Data.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043012
By:
- Zomer, Aldert;
- Burghout, Peter;
- Bootsma, Hester J.;
- Hermans, Peter W. M.;
- van Hijum, Sacha A. F. T.;
- Provart, Nicholas James
Publication type:
Article
Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.
Published in:
2016
By:
- van der Maten, Erika;
- Westra, Dineke;
- van Selm, Saskia;
- Langereis, Jeroen D.;
- Bootsma, Hester J.;
- van Opzeeland, Fred J. H.;
- de Groot, Ronald;
- Ruseva, Marieta M.;
- Pickering, Matthew C.;
- van den Heuvel, Lambert P. W. J.;
- van de Kar, Nicole C. A. J.;
- de Jonge, Marien I.;
- van der Flier, Michiel
Publication type:
journal article
Pneumococcal genetic variability in age-dependent bacterial carriage.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.69244
By:
- Kremer, Philip H. C.;
- Ferwerda, Bart;
- Bootsma, Hester J.;
- Rots, Nienke Y.;
- Wijmenga-Monsuur, Alienke J.;
- Sanders, Elisabeth A. M.;
- Trzciński, Krzysztof;
- Wyllie, Anne L.;
- Turner, Paul;
- van der Ende, Arie;
- Brouwer, Matthijs C.;
- Bentley, Stephen D.;
- van de Beek, Diederik;
- Lees, John A.
Publication type:
Article
Fine-tuning of choline metabolism is important for pneumococcal colonization.
Published in:
Molecular Microbiology, 2016, v. 100, n. 6, p. 972, doi. 10.1111/mmi.13360
By:
- Johnston, Calum;
- Hauser, Christoph;
- Hermans, Peter W. M.;
- Martin, Bernard;
- Polard, Patrice;
- Bootsma, Hester J.;
- Claverys, Jean‐Pierre
Publication type:
Article
Deciphering the genetic basis of Moraxella catarrhalis complement resistance: a critical role for the disulphide bond formation system.
Published in:
Molecular Microbiology, 2014, v. 91, n. 3, p. 522, doi. 10.1111/mmi.12475
By:
- Vries, Stefan P. W.;
- Rademakers, Rob J. A.;
- Gaast‐de Jongh, Christa E.;
- Eleveld, Marc J.;
- Hermans, Peter W. M.;
- Bootsma, Hester J.
Publication type:
Article
Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions.
Published in:
Molecular Microbiology, 2013, v. 87, n. 1, p. 14, doi. 10.1111/mmi.12081
By:
- Vries, Stefan P. W.;
- Burghout, Peter;
- Langereis, Jeroen D.;
- Zomer, Aldert;
- Hermans, Peter W. M.;
- Bootsma, Hester J.
Publication type:
Article
Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09976-3
By:
- Lees, John A.;
- Ferwerda, Bart;
- Kremer, Philip H. C.;
- Wheeler, Nicole E.;
- Serón, Mercedes Valls;
- Croucher, Nicholas J.;
- Gladstone, Rebecca A.;
- Bootsma, Hester J.;
- Rots, Nynke Y.;
- Wijmega-Monsuur, Alienke J.;
- Sanders, Elisabeth A. M.;
- Trzciński, Krzysztof;
- Wyllie, Anne L.;
- Zwinderman, Aeilko H.;
- van den Berg, Leonard H.;
- van Rheenen, Wouter;
- Veldink, Jan H.;
- Harboe, Zitta B.;
- Lundbo, Lene F.;
- de Groot, Lisette C. P. G. M.
Publication type:
Article
Comparative Genomic Analyses of the Moraxella catarrhalis Serosensitive and Seroresistant Lineages Demonstrate Their Independent Evolution.
Published in:
Genome Biology & Evolution, 2016, v. 8, n. 4, p. 955, doi. 10.1093/gbe/evw039
By:
- Earl, Joshua P.;
- de Vries, Stefan P.W.;
- Ahmed, Azad;
- Powell, Evan;
- Schultz, Matthew P.;
- Hermans, Peter W.M.;
- Hill, Darryl J.;
- Zhou, Zhemin;
- Constantinidou, Crystala I.;
- Hu, Fen Z.;
- Bootsma, Hester J.;
- Ehrlich, Garth D.
Publication type:
Article
Influenza-like Illness Exacerbates Pneumococcal Carriage in Older Adults.
Published in:
Clinical Infectious Diseases, 2021, v. 73, n. 9, p. e2680, doi. 10.1093/cid/ciaa1551
By:
- Miellet, Willem R;
- Veldhuizen, Janieke van;
- Nicolaie, Mioara A;
- Mariman, Rob;
- Bootsma, Hester J;
- Bosch, Thijs;
- Rots, Nynke Y;
- Sanders, Elisabeth A M;
- Beek, Josine van;
- Trzciński, Krzysztof
Publication type:
Article
The Contribution of Genetic Variation of Streptococcus pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease.
Published in:
Clinical Infectious Diseases, 2019, v. 68, n. 1, p. 61, doi. 10.1093/cid/ciy417
By:
- Cremers, Amelieke J H;
- Mobegi, Fredrick M;
- Jongh, Christa van der Gaast–de;
- Weert, Michelle van;
- Opzeeland, Fred J van;
- Vehkala, Minna;
- Knol, Mirjam J;
- Bootsma, Hester J;
- Välimäki, Niko;
- Croucher, Nicholas J;
- Meis, Jacques F;
- Bentley, Stephen;
- Hijum, Sacha A F T van;
- Corander, Jukka;
- Zomer, Aldert L;
- Ferwerda, Gerben;
- Jonge, Marien I de
Publication type:
Article
Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice.
Published in:
PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149307
By:
- van der Maten, Erika;
- van Selm, Saskia;
- Langereis, Jeroen D.;
- Bootsma, Hester J.;
- van Opzeeland, Fred J. H.;
- de Groot, Ronald;
- de Jonge, Marien I.;
- van der Flier, Michiel
Publication type:
Article
Natural Genetic Transformation Generates a Population of Merodiploids in Streptococcus pneumoniae.
Published in:
PLoS Genetics, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.pgen.1003819
By:
- Johnston, Calum;
- Caymaris, Stéphanie;
- Zomer, Aldert;
- Bootsma, Hester J.;
- Prudhomme, Marc;
- Granadel, Chantal;
- Hermans, Peter W. M.;
- Polard, Patrice;
- Martin, Bernard;
- Claverys, Jean-Pierre
Publication type:
Article
Adaptation of Bordetella pertussis to the Respiratory Tract.
Published in:
2018
By:
- van Beek, Lucille F.;
- de Gouw, Daan;
- Eleveld, Marc J.;
- Bootsma, Hester J.;
- de Jonge, Marien I.;
- Mooi, Frits R.;
- Zomer, Aldert;
- Diavatopoulos, Dimitri A.
Publication type:
journal article
From microbial gene essentiality to novel antimicrobial drug targets.
Published in:
BMC Genomics, 2014, v. 15, n. 1, p. 958, doi. 10.1186/1471-2164-15-958
By:
- Mobegi, Fredrick M.;
- van Hijum, Sacha A. F. T.;
- Burghout, Peter;
- Bootsma, Hester J.;
- de Vries, Stefan P. W.;
- van der Gaast-de Jongh, Christa E.;
- Simonetti, Elles;
- Langereis, Jeroen D.;
- Hermans, Peter W. M.;
- de Jonge, Marien I.;
- Zomer, Aldert
Publication type:
Article
Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.
Published in:
BMC Genomics, 2014, v. 15, n. 1, p. 863, doi. 10.1186/1471-2164-15-863
By:
- Tavares, Débora A.;
- Simões, Alexandra S.;
- Bootsma, Hester J.;
- Hermans, Peter W. M.;
- de Lencastre, Hermínia;
- Sá-Leão, Raquel
Publication type:
Article
Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates.
Published in:
BMC Genomics, 2011, v. 12, p. 1, doi. 10.1186/1471-2164-12-70
By:
- Davie, Jeremiah J;
- Earl, Josh;
- de Vries, Stefan PW;
- Ahmed, Azad;
- Hu, Fen Z;
- Bootsma, Hester J;
- Stol, Kim;
- Hermans, Peter WM;
- Wadowsky, Robert M;
- Ehrlich, Garth D;
- Hays, John P;
- Campagnari, Anthony A
Publication type:
Article
Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates.
Published in:
BMC Genomics, 2011, v. 12, n. 1, p. 70, doi. 10.1186/1471-2164-12-70
By:
- Davie, Jeremiah J.;
- Earl, Josh;
- de Vries, Stefan P. W.;
- Ahmed, Azad;
- Hu, Fen Z.;
- Bootsma, Hester J.;
- Stol, Kim;
- Hermans, Peter W. M.;
- Wadowsky, Robert M.;
- Ehrlich, Garth D.;
- Hays, John P.;
- Campagnari, Anthony A.
Publication type:
Article
Non-lytic antibiotic treatment in community-acquired pneumococcal pneumonia does not attenuate inflammation: the PRISTINE trial.
Published in:
2019
By:
- Groeneveld, Geert H;
- Reyden, Tanny J van der;
- Joosten, Simone A;
- Bootsma, Hester J;
- Cobbaert, Christa M;
- Vries, Jutte J C de;
- Kuijper, Ed J;
- Dissel, Jaap T van;
- van der Reyden, Tanny J;
- de Vries, Jutte J C;
- van Dissel, Jaap T
Publication type:
journal article

Found: 32

Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells.

Analysis of Moraxella catarrhalis by DNA Typing: Evidence for a Distinct Subpopulation Associated with Virulence Traits.

Distribution of serotypes and patterns of antimicrobial resistance among commensal Streptococcus pneumoniae in nine European countries.

The global nutritional regulator CodY is an essential protein in the human pathogen Streptococcus pneumoniae.

Diversity in the Bordetella virulence regulon: transcriptional control of a Bvg-intermediate phase gene.

Genesis of BRO β-lactamase-producing Moraxella catarrhalis: evidence for transformation-mediated horizontal transfer.

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.

Co-Inactivation of GlnR and CodY Regulators Impacts Pneumococcal Cell Wall Physiology.

The Carbapenem Inactivation Method (CIM), a Simple and Low-Cost Alternative for the Carba NP Test to Assess Phenotypic Carbapenemase Activity in Gram-Negative Rods.

The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice.

Genome-Wide Identification of Genes Essential for the Survival of <i>Streptococcus pneumoniae</i> in Human Saliva.

Differentially Expressed Genes in <i>Bordetella pertussis</i> Strains Belonging to a Lineage Which Recently Spread Globally.

<i>Streptococcus pneumoniae</i> Serine Protease HtrA, but Not SFP or PrtA, Is a Major Virulence Factor in Pneumonia.

Characterization of the Molecular Interplay between <i>Moraxella catarrhalis</i> and Human Respiratory Tract Epithelial Cells.

ESSENTIALS: Software for Rapid Analysis of High Throughput Transposon Insertion Sequencing Data.

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.

Pneumococcal genetic variability in age-dependent bacterial carriage.

Fine-tuning of choline metabolism is important for pneumococcal colonization.

Deciphering the genetic basis of Moraxella catarrhalis complement resistance: a critical role for the disulphide bond formation system.

Genetic requirements for Moraxella catarrhalis growth under iron-limiting conditions.

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis.

Comparative Genomic Analyses of the Moraxella catarrhalis Serosensitive and Seroresistant Lineages Demonstrate Their Independent Evolution.

Influenza-like Illness Exacerbates Pneumococcal Carriage in Older Adults.

The Contribution of Genetic Variation of Streptococcus pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease.

Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice.

Natural Genetic Transformation Generates a Population of Merodiploids in <i>Streptococcus pneumoniae</i>.

Adaptation of Bordetella pertussis to the Respiratory Tract.

From microbial gene essentiality to novel antimicrobial drug targets.

Non-typeable pneumococci circulating in Portugal are of cps type NCC2 and have genomic features typical of encapsulated isolates.

Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates.

Comparative analysis and supragenome modeling of twelve Moraxella catarrhalis clinical isolates.

Non-lytic antibiotic treatment in community-acquired pneumococcal pneumonia does not attenuate inflammation: the PRISTINE trial.