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A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo.
Published in:
Oncogene, 2013, v. 32, n. 37, p. 4406, doi. 10.1038/onc.2012.460
By:
- Eberlein, C;
- Kendrew, J;
- McDaid, K;
- Alfred, A;
- Kang, J S;
- Jacobs, V N;
- Ross, S J;
- Rooney, C;
- Smith, N R;
- Rinkenberger, J;
- Cao, A;
- Churchman, A;
- Marshall, J F;
- Weir, H M;
- Bedian, V;
- Blakey, D C;
- Foltz, I N;
- Barry, S T
Publication type:
Article
Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma.
Published in:
2008
By:
- Fens, M H A M;
- Hill, K J;
- Issa, J;
- Ashton, S E;
- Westwood, F R;
- Blakey, D C;
- Storm, G;
- Ryan, A J;
- Schiffelers, R M
Publication type:
journal article
Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging.
Published in:
2003
By:
- Robinson, S P;
- McIntyre, D J O;
- Checkley, D;
- Tessier, J J;
- Howe, F A;
- Griffiths, J R;
- Ashton, S E;
- Ryan, A J;
- Blakey, D C;
- Waterton, J C
Publication type:
journal article
Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue.
Published in:
British Journal of Cancer, 2001, v. 85, n. 5, p. 764, doi. 10.1054/bjoc.2001.1947
By:
- Monks, N R;
- Blakey, D C;
- Curtin, N J;
- East, S J;
- Heuze, A;
- Newell, D R
Publication type:
Article
Cellular glutathione as a determinant of the sensitivity of colorectal tumour cell-lines to ZD2767 antibody-directed enzyme prodrug therapy (ADEPT).
Published in:
British Journal of Cancer, 2000, v. 83, n. 2, p. 267, doi. 10.1054/bjoc.2000.1240
By:
- Monks, N R;
- Calvete, J A;
- Curtin, N J;
- Blakey, D C;
- East, S J;
- Newell, D R
Publication type:
Article

Found: 5

A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo.

Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma.

Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging.

Induction of apoptosis by the ADEPT agent ZD2767: comparison with the classical nitrogen mustard chlorambucil and a monofunctional ZD2767 analogue.

Cellular glutathione as a determinant of the sensitivity of colorectal tumour cell-lines to ZD2767 antibody-directed enzyme prodrug therapy (ADEPT).