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CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16933-6
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- Publication type:
- Article
Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05193-z
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- Publication type:
- Article
Non‐canonical cMet regulation by vimentin mediates Plk1 inhibitor–induced apoptosis.
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- EMBO Molecular Medicine, 2019, v. 11, n. 5, p. N.PAG, doi. 10.15252/emmm.201809960
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- Publication type:
- Article
Gene Therapy of Pancreatic Cancer With Green Fluorescent Protein and Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Fusion Gene Expression Driven by a Human Telomerase Reverse Transcriptase Promoter.
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- Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2003, v. 10, n. 7, p. 762, doi. 10.1245/ASO.2003.01.021
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- Publication type:
- Article
Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer.
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- Annals of Surgical Oncology: An Oncology Journal for Surgeons, 1998, v. 5, n. 8, p. 681, doi. 10.1007/BF02303477
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- Publication type:
- Article
mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21841-w
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- Publication type:
- Article
TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin.
- Published in:
- Scientific Reports, 2016, p. 35741, doi. 10.1038/srep35741
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- Publication type:
- Article
Downregulation of IFNG in CD4<sup>+</sup> T Cells in Lung Cancer through Hypermethylation: A Possible Mechanism of Tumor-Induced Immunosuppression.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079064
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- Publication type:
- Article
The Tumor Suppressor Gene TUSC2 (FUS1) Sensitizes NSCLC to the AKT Inhibitor MK2206 in LKB1-dependent Manner.
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- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077067
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- Publication type:
- Article
Insulin-Like Growth Factor Binding Protein-2 Level Is Increased in Blood of Lung Cancer Patients and Associated with Poor Survival.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074973
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- Publication type:
- Article
Aberrant Expression of Proteins Involved in Signal Transduction and DNA Repair Pathways in Lung Cancer and Their Association with Clinical Parameters.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031087
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- Publication type:
- Article
Antitumor Activity of a Novel Oncrasin Analogue Is Mediated by JNK Activation and STAT3 Inhibition.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0028487
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- Publication type:
- Article
The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0024855
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- Publication type:
- Article
Combination Treatment with MEK and AKT Inhibitors Is More Effective than Each Drug Alone in Human Non-Small Cell Lung Cancer In Vitro and In Vivo.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014124
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- Publication type:
- Article
Apoptosis Induction by MEK Inhibition in Human Lung Cancer Cells Is Mediated by Bim.
- Published in:
- PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0013026
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- Publication type:
- Article
Bcl-2-associated X protein is the main mediator of manumycin a-induced apoptosis in anaplastic thyroid cancer cells.
- Published in:
- 2005
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- Publication type:
- journal article
Insulin-Like Growth Factor Binding Protein-6 Inhibits the Growth of Human Bronchial Epithelial Cells and Increases in Abundance with All-trans-Retinoic Acid Treatment.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2000, v. 23, n. 3, p. 297, doi. 10.1165/ajrcmb.23.3.4013
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- Publication type:
- Article
Use of the Probasin Promoter ARR[sub 2]PB to Express Bax in Androgen Receptor-Positive Prostate....
- Published in:
- JNCI: Journal of the National Cancer Institute, 2001, v. 93, n. 17, p. 1314, doi. 10.1093/jnci/93.17.1314
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- Publication type:
- Article
Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors.
- Published in:
- Oncogene, 2005, v. 24, n. 31, p. 4993, doi. 10.1038/sj.onc.1208683
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- Publication type:
- Article
Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
- Published in:
- Oncogene, 2004, v. 23, n. 29, p. 4984, doi. 10.1038/sj.onc.1207645
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- Publication type:
- Article
Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis.
- Published in:
- Oncogene, 2004, v. 23, n. 6, p. 1300, doi. 10.1038/sj.onc.1207239
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- Publication type:
- Article
Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumorgrowth in a model of human ovarian cancer.
- Published in:
- Oncogene, 2003, v. 22, n. 36, p. 5694, doi. 10.1038/sj.onc.1206858
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- Publication type:
- Article
Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells.
- Published in:
- Oncogene, 2002, v. 21, n. 52, p. 8020, doi. 10.1038/sj.onc.1205926
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- Publication type:
- Article
A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo.
- Published in:
- Oncogene, 2002, v. 21, n. 31, p. 4757, doi. 10.1038/sj.onc.1205582
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- Publication type:
- Article
Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 sequences.
- Published in:
- Oncogene, 2002, v. 21, n. 1, p. 87, doi. 10.1038/sj.onc.1204999
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- Publication type:
- Article
Genetic Interactions of STAT3 and Anticancer Drug Development.
- Published in:
- Cancers, 2014, v. 6, n. 1, p. 494, doi. 10.3390/cancers6010494
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- Publication type:
- Article
Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells.
- Published in:
- Oncogene, 2000, v. 19, n. 38, p. 4432, doi. 10.1038/sj.onc.1203813
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- Publication type:
- Article
Induction of apoptosis and G2/M cell cycle arrest by DCC.
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- Oncogene, 1999, v. 18, n. 17, p. 2747, doi. 10.1038/sj.onc.1202629
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- Publication type:
- Article
Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer.
- Published in:
- Breast Cancer Research, 2013, v. 15, n. 1, p. 1, doi. 10.1186/bcr3374
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- Publication type:
- Article
Elafin, an inhibitor of elastase, is a prognostic indicator in breast cancer.
- Published in:
- 2013
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- Publication type:
- journal article
Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer.
- Published in:
- 2018
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- Publication type:
- journal article
Mechanisms of resistance to TRAIL-induced apoptosis in cancer.
- Published in:
- Cancer Gene Therapy, 2005, v. 12, n. 3, p. 228, doi. 10.1038/sj.cgt.7700792
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- Publication type:
- Article
Suppression of pancreatic tumor growth in the liver by systemic administration of the TRAIL gene driven by the hTERT promoter.
- Published in:
- Cancer Gene Therapy, 2005, v. 12, n. 2, p. 109, doi. 10.1038/sj.cgt.7700773
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- Publication type:
- Article
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
- Published in:
- Cancer Gene Therapy, 2004, v. 11, n. 4, p. 249, doi. 10.1038/sj.cgt.7700684
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- Publication type:
- Article
Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma.
- Published in:
- Cancer Gene Therapy, 2001, v. 8, n. 8, p. 547, doi. 10.1038/sj.cgt.7700332
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- Publication type:
- Article
Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type p53 (Ad-p53).
- Published in:
- Cancer Gene Therapy, 2000, v. 7, n. 4, p. 530, doi. 10.1038/sj.cgt.7700138
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- Publication type:
- Article
Adenovirus-mediated small hairpin RNA targeting Bcl-XL as therapy for colon cancer.
- Published in:
- International Journal of Cancer, 2007, v. 121, n. 6, p. 1366, doi. 10.1002/ijc.22856
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- Publication type:
- Article
Immunotherapy for non-small cell lung cancers: biomarkers for predicting responses and strategies to overcome resistance.
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- 2018
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- Publication type:
- journal article
RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
- Published in:
- Acta Biochimica et Biophysica Sinica, 2016, v. 48, n. 1, p. 27, doi. 10.1093/abbs/gmv090
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- Publication type:
- Article
Antitumor activity and downregulation of pro‐angiogenic molecules in human prostate cancer cells by a novel thiazolidione compoundFuminori Teraishi and Shuhong Wu contributed equally to this study.
- Published in:
- Prostate, 2006, v. 66, n. 4, p. 430, doi. 10.1002/pros.20373
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- Publication type:
- Article
Repurposing auranofin to treat TP53-mutated or PTEN-deleted refractory B-cell lymphoma.
- Published in:
- 2019
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- Publication type:
- Letter to the Editor
Oxidative stress in NSC-741909-induced apoptosis of cancer cells.
- Published in:
- Journal of Translational Medicine, 2010, v. 8, p. 37, doi. 10.1186/1479-5876-8-37
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- Publication type:
- Article
Therapeutic Molecular Targetingof 15-Lipoxygenase-1 in Colon Cancer.
- Published in:
- Molecular Therapy, 2008, v. 16, n. 5, p. 886, doi. 10.1038/mt.2008.44
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- Publication type:
- Article
1004. c-Jun NH2-Terminal Kinase (JNK)1 and JNK2 Have Distinct Roles in Adenovirus-Mediated Transgene Expression.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S387, doi. 10.1016/j.ymthe.2006.08.1098
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- Publication type:
- Article
539. Antitumor Activity of an hTERT-Specific, GFP Expressing Oncolytic Adenovirus
- Published in:
- 2005
- By:
- Publication type:
- Abstract
Overcoming Acquired Resistance to TRAIL by Chemotherapeutic Agents and Calpain Inhibitor I through Distinct Mechanisms
- Published in:
- Molecular Therapy, 2004, v. 9, n. 5, p. 666, doi. 10.1016/j.ymthe.2004.02.007
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- Publication type:
- Article
Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers
- Published in:
- Molecular Therapy, 2003, v. 8, n. 3, p. 441, doi. 10.1016/S1525-0016(03)00203-X
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- Publication type:
- Article
Differential Expression of Viral Transcripts From Single-Cell RNA Sequencing of Moderate and Severe COVID-19 Patients and Its Implications for Case Severity.
- Published in:
- Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.603509
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- Publication type:
- Article
α-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of β-catenin transactivation.
- Published in:
- Journal of Neuro-Oncology, 2011, v. 103, n. 3, p. 445, doi. 10.1007/s11060-010-0413-4
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- Publication type:
- Article
3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04889-w
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- Publication type:
- Article