Found: 110
Select item for more details and to access through your institution.
Key factors in the discovery and development of new antiepileptic drugs.
- Published in:
- 2010
- By:
- Publication type:
- journal article
sec-Butyl-propylacetamide (SPD) and two of its stereoisomers rapidly terminate paraoxon-induced status epilepticus in rats.
- Published in:
- Epilepsia (Series 4), 2014, v. 55, n. 12, p. 1953, doi. 10.1111/epi.12838
- By:
- Publication type:
- Article
Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
- Published in:
- Epilepsia (Series 4), 2014, v. 55, n. 12, p. 1944, doi. 10.1111/epi.12857
- By:
- Publication type:
- Article
Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
- Published in:
- Epilepsia (Series 4), 2014, v. 55, n. 2, p. 353, doi. 10.1111/epi.12480
- By:
- Publication type:
- Article
Valnoctamide and sec-butyl-propylacetamide ( SPD) for acute seizures and status epilepticus.
- Published in:
- Epilepsia (Series 4), 2013, v. 54, p. 99, doi. 10.1111/epi.12290
- By:
- Publication type:
- Article
Comparative steady-state pharmacokinetic evaluation of immediate-release topiramate and USL255, a once-daily extended-release topiramate formulation.
- Published in:
- Epilepsia (Series 4), 2013, v. 54, n. 8, p. 1444, doi. 10.1111/epi.12225
- By:
- Publication type:
- Article
Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers.
- Published in:
- Epilepsia (Series 4), 2013, v. 54, n. 8, p. 1453, doi. 10.1111/epi.12242
- By:
- Publication type:
- Article
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
- Published in:
- Epilepsia (Series 4), 2012, v. 53, p. 3, doi. 10.1111/epi.12024
- By:
- Publication type:
- Article
Introduction.
- Published in:
- Epilepsia (Series 4), 2012, v. 53, p. 1, doi. 10.1111/epi.12023
- By:
- Publication type:
- Article
Introduction.
- Published in:
- Epilepsia (Series 4), 2012, v. 53, p. 1, doi. 10.1111/j.1528-1167.2012.03708.x
- By:
- Publication type:
- Article
Why are antiepileptic drugs used for nonepileptic conditions?
- Published in:
- Epilepsia (Series 4), 2012, v. 53, p. 26, doi. 10.1111/j.1528-1167.2012.03712.x
- By:
- Publication type:
- Article
Why are antiepileptic drugs used for nonepileptic conditions?
- Published in:
- Epilepsia (Series 4), 2012, p. 26, doi. 10.1111/j.1528-1167.2012.03712.x
- By:
- Publication type:
- Article
Introduction.
- Published in:
- Epilepsia (Series 4), 2012, p. 1, doi. 10.1111/j.1528-1167.2012.03708.x
- By:
- Publication type:
- Article
Comments on the working group's 2012 review of the Program.
- Published in:
- Epilepsia (Series 4), 2012, v. 53, n. 10, p. 1844, doi. 10.1111/j.1528-1167.2012.03682.x
- By:
- Publication type:
- Article
Pharmacokinetics and drug interactions of eslicarbazepine acetate.
- Published in:
- Epilepsia (Series 4), 2012, v. 53, n. 6, p. 935, doi. 10.1111/j.1528-1167.2012.03519.x
- By:
- Publication type:
- Article
A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.
- Published in:
- Epilepsia (Series 4), 2012, v. 53, n. 1, p. 134, doi. 10.1111/j.1528-1167.2011.03338.x
- By:
- Publication type:
- Article
Comparative pharmacokinetic analysis of USL255, a new once-daily extended-release formulation of topiramate.
- Published in:
- Epilepsia (Series 4), 2011, v. 52, n. 10, p. 1877, doi. 10.1111/j.1528-1167.2011.03183.x
- By:
- Publication type:
- Article
Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
- Published in:
- Epilepsia (Series 4), 2010, v. 51, n. 10, p. 1944, doi. 10.1111/j.1528-1167.2010.02684.x
- By:
- Publication type:
- Article
Generic products of antiepileptic drugs: A perspective on bioequivalence and interchangeability.
- Published in:
- Epilepsia (Series 4), 2010, v. 51, n. 6, p. 941, doi. 10.1111/j.1528-1167.2010.02573.x
- By:
- Publication type:
- Article
Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): A chiral stereoisomer of valproic acid urea derivative.
- Published in:
- Epilepsia (Series 4), 2010, v. 51, n. 3, p. 323, doi. 10.1111/j.1528-1167.2009.02241.x
- By:
- Publication type:
- Article
Pharmacodynamic and pharmacokinetic characteristics of intravenous drugs in status epilepticus.
- Published in:
- Epilepsia (Series 4), 2009, v. 50, p. 44, doi. 10.1111/j.1528-1167.2009.02348.x
- By:
- Publication type:
- Article
Pharmacokinetics of carisbamate (RWJ-333369) in healthy Japanese and Western subjects.
- Published in:
- Epilepsia (Series 4), 2009, v. 50, n. 8, p. 1850, doi. 10.1111/j.1528-1167.2009.02081.x
- By:
- Publication type:
- Article
Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: A potential for a second generation drug to valproic acid.
- Published in:
- Epilepsia (Series 4), 2008, v. 49, n. 7, p. 1202, doi. 10.1111/j.1528-1167.2008.01624.x
- By:
- Publication type:
- Article
Clinical pharmacology of parenteral use of antiepileptic drugs.
- Published in:
- Epilepsia (Series 4), 2007, v. 48, p. 46, doi. 10.1111/j.1528-1167.2007.01348.x
- By:
- Publication type:
- Article
Generic Products of Antiepileptic Drugs (AEDs): Is It an Issue?
- Published in:
- Epilepsia (Series 4), 2007, v. 48, n. 10, p. 1825, doi. 10.1111/j.1528-1167.2007.01272.x
- By:
- Publication type:
- Article
An Interaction Study Between the New Antiepileptic and CNS Drug Carisbamate (RWJ-333369) and Lamotrigine and Valproic Acid.
- Published in:
- Epilepsia (Series 4), 2007, v. 48, n. 7, p. 1328, doi. 10.1111/j.1528-1167.2007.01037.x
- By:
- Publication type:
- Article
Eslicarbazepine Acetate: A Double-blind, Add-on, Placebo-controlled Exploratory Trial in Adult Patients with Partial-onset Seizures.
- Published in:
- Epilepsia (Series 4), 2007, v. 48, n. 3, p. 497, doi. 10.1111/j.1528-1167.2007.00984.x
- By:
- Publication type:
- Article
Pharmacokinetics of the New Antiepileptic and CNS Drug RWJ-333369 Following Single and Multiple Dosing to Humans.
- Published in:
- Epilepsia (Series 4), 2006, v. 47, n. 11, p. 1822, doi. 10.1111/j.1528-1167.2006.00814.x
- By:
- Publication type:
- Article
Pharmacokinetic Interaction Study between the New Antiepileptic and CNS Drug RWJ-333369 and Carbamazepine in Healthy Adults.
- Published in:
- Epilepsia (Series 4), 2006, v. 47, n. 11, p. 1830, doi. 10.1111/j.1528-1167.2006.00815.x
- By:
- Publication type:
- Article
A Comparative Study of the Effect of Carbamazepine and Valproic Acid on the Pharmacokinetics and Metabolic Profile of Topiramate at Steady State in Patients with Epilepsy.
- Published in:
- Epilepsia (Series 4), 2005, v. 46, n. 7, p. 1046, doi. 10.1111/j.1528-1167.2005.06805.x
- By:
- Publication type:
- Article
Pharmacokinetic and Metabolic Investigation of Topiramate Disposition in Healthy Subjects in the Absence and in the Presence of Enzyme Induction by Carbamazepine.
- Published in:
- Epilepsia (Series 4), 2005, v. 46, n. 3, p. 378, doi. 10.1111/j.0013-9580.2005.55204.x
- By:
- Publication type:
- Article
The Activity of Antiepileptic Drugs as Histone Deacetylase Inhibitors.
- Published in:
- Epilepsia (Series 4), 2004, v. 45, n. 7, p. 737, doi. 10.1111/j.0013-9580.2004.00104.x
- By:
- Publication type:
- Article
Topiramate and Lamotrigine Pharmacokinetics during Repetitive Monotherapy and Combination Therapy in Epilepsy Patients.
- Published in:
- Epilepsia (Series 4), 2003, v. 44, n. 7, p. 917, doi. 10.1046/j.1528-1157.2003.64402.x
- By:
- Publication type:
- Article
Effect of Topiramate or Carbamazepine on the Pharmacokinetics of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol in Healthy Obese and Nonobese Female Subjects.
- Published in:
- Epilepsia (Series 4), 2003, v. 44, n. 4, p. 540, doi. 10.1046/j.1528-1157.2003.55602.x
- By:
- Publication type:
- Article
Interlaboratory Variability in the Quantification of New Generation Antiepileptic Drugs Based on External Quality Assessment Data.
- Published in:
- Epilepsia (Series 4), 2003, v. 44, n. 1, p. 40, doi. 10.1046/j.1528-1157.2003.26702.x
- By:
- Publication type:
- Article
Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients.
- Published in:
- 2002
- By:
- Publication type:
- Correction Notice
Topiramate and Phenytoin Pharmacokinetics During Repetitive Monotherapy and Combination Therapy to Epileptic Patients.
- Published in:
- Epilepsia (Series 4), 2002, v. 43, n. 7, p. 691, doi. 10.1046/j.1528-1157.2002.41701.x
- By:
- Publication type:
- Article
Anticonvulsant Profile and Teratogenicity of N -methyl-tetramethylcyclopropyl Carboxamide: A New Antiepileptic Drug.
- Published in:
- Epilepsia (Series 4), 2002, v. 43, n. 2, p. 115, doi. 10.1046/j.1528-1157.2002.25801.x
- By:
- Publication type:
- Article
Anticonvulsant Profile of Valrocemide (TV1901): A New Antiepileptic Drug.
- Published in:
- Epilepsia (Series 4), 2001, v. 42, n. 7, p. 831, doi. 10.1046/j.1528-1157.2001.042007831.x
- By:
- Publication type:
- Article
Pharmacokinetics of Levetiracetam and Its Enantiomer (R)-α-ethyl-2-oxo-pyrrolidine acetamide in Dogs.
- Published in:
- Epilepsia (Series 4), 2001, v. 42, n. 7, p. 825, doi. 10.1046/j.1528-1157.2001.042007825.x
- By:
- Publication type:
- Article
Synthesis and Enantioselective Pharmacokinetic/Pharmacodynamic Analysis of New CNS-Active Sulfamoylphenyl Carbamate Derivatives.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3361, doi. 10.3390/ijms22073361
- By:
- Publication type:
- Article
Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase.
- Published in:
- International Journal of Molecular Sciences, 2017, v. 18, n. 9, p. 1912, doi. 10.3390/ijms18091912
- By:
- Publication type:
- Article
Structure elucidation of a condensation product of 4-aminopyrrole derivatives and dicyclohexylcarbodiimide.
- Published in:
- Journal of Heterocyclic Chemistry, 1980, v. 17, n. 8, p. 1797, doi. 10.1002/jhet.5570170834
- By:
- Publication type:
- Article
sec-Butylpropylacetamide (SPD) has antimigraine properties.
- Published in:
- Cephalalgia, 2016, v. 36, n. 10, p. 924, doi. 10.1177/0333102415612773
- By:
- Publication type:
- Article
Anticonvulsant activity, teratogencity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
- Published in:
- British Journal of Pharmacology, 2003, v. 139, n. 4, p. 755, doi. 10.1038/sj.bjp.0705301
- By:
- Publication type:
- Article
Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
- Published in:
- 2003
- By:
- Publication type:
- journal article
Use of mean residence time to determine the magnitude of difference between rate constants and to calculate t<sub>max</sub> in the Bateman equation.
- Published in:
- Biopharmaceutics & Drug Disposition, 1999, v. 20, n. 1, p. 3, doi. 10.1002/(SICI)1099-081X(199901)20:1<3::AID-BDD146>3.0.CO;2-7
- By:
- Publication type:
- Article
Pharmacokinetic analysis and antiepileptic activity of two new isomers of N-valproyl glycinamide.
- Published in:
- Biopharmaceutics & Drug Disposition, 1997, v. 18, n. 7, p. 557, doi. 10.1002/(SICI)1099-081X(199710)18:7<557::AID-BDD48>3.0.CO;2-D
- By:
- Publication type:
- Article
PHARMACOKINETIC AND PHARMACODYNAMIC ANALYSIS OF (E)-2-ENE VALPROYL DERIVATIVES OF GLYCINE AND VALPROYL DERIVATIVES OF NIPECOTIC ACID.
- Published in:
- Biopharmaceutics & Drug Disposition, 1996, v. 17, n. 7, p. 565, doi. 10.1002/(SICI)1099-081X(199610)17:7<565::AID-BDD979>3.0.CO;2-I
- By:
- Publication type:
- Article
Pharmacokinetic analysis of diethylcarbonate prodrugs of ibuprofen and naproxen.
- Published in:
- Biopharmaceutics & Drug Disposition, 1995, v. 16, n. 3, p. 201, doi. 10.1002/bdd.2510160305
- By:
- Publication type:
- Article