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Complex formation of anti-VEGF-C with VEGF-C released during blood coagulation resulted in an artifact in its serum pharmacokinetics.
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- Pharmacology Research & Perspectives, 2020, v. 8, n. 2, p. 1, doi. 10.1002/prp2.573
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- Article
Maximizing tumour exposure to anti-neuropilin-1 antibody requires saturation of non-tumour tissue antigenic sinks in mice.
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- British Journal of Pharmacology, 2012, v. 166, n. 1, p. 368, doi. 10.1111/j.1476-5381.2011.01777.x
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- Article
Trastuzumab does not bind rat or mouse ErbB2/neu: implications for selection of non-clinical safety models for trastuzumab-based therapeutics.
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- Breast Cancer Research & Treatment, 2022, v. 191, n. 2, p. 303, doi. 10.1007/s10549-021-06427-w
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- Article
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates.
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- Nature Biotechnology, 2012, v. 30, n. 2, p. 184, doi. 10.1038/nbt.2108
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- Article
A Mechanistic Pharmacokinetic Model Elucidating the Disposition of Trastuzumab Emtansine (T-DM1), an Antibody-Drug Conjugate (ADC) for Treatment of Metastatic Breast Cancer.
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- AAPS Journal, 2014, v. 16, n. 5, p. 994, doi. 10.1208/s12248-014-9618-3
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- Article
Physiologically Based Pharmacokinetic Modeling as a Tool to Predict Drug Interactions for Antibody-Drug Conjugates.
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- Clinical Pharmacokinetics, 2015, v. 54, n. 1, p. 81, doi. 10.1007/s40262-014-0182-x
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- Article
Preclinical Characterization of the Distribution, Catabolism, and Elimination of a Polatuzumab Vedotin-Piiq (POLIVY ®) Antibody–Drug Conjugate in Sprague Dawley Rats.
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- Journal of Clinical Medicine, 2021, v. 10, n. 6, p. 1323, doi. 10.3390/jcm10061323
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- Article