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Assessing the Role of PLCG2*M28L Risk In A Novel Mouse Model Late‐Onset Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079180
By:
- Territo, Paul R;
- Oblak, Adrian L;
- Persohn, Scott C;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Kotredes, Kevin P;
- Pandey, Ravi S;
- Rizzo, Stacey J Sukoff;
- Carter, Gregory W;
- Sasner, Michael;
- Howell, Gareth R;
- Lamb, Bruce T
Publication type:
Article
Characterization of brain metabolism, volume, and vasculature of the 5xFAD mouse model of Alzheimer's Disease across lifespan.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077201
By:
- Jullienne, Amandine;
- Szu, Jenny;
- Quan, Ryan;
- Trinh, Michelle V;
- Norouzi, Tannoz;
- Noarbe, Brenda P;
- Silvola, Rebecca;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Persohn, Scott C;
- Territo, Paul R;
- Obenaus, Andre
Publication type:
Article
Characterization of brain metabolism, volume, and vasculature of the 5xFAD mouse model of Alzheimer's Disease across lifespan.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081753
By:
- Jullienne, Amandine;
- Szu, Jenny;
- Quan, Ryan;
- Trinh, Michelle V;
- Norouzi, Tannoz;
- Noarbe, Brenda P;
- Silvola, Rebecca;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Persohn, Scott C;
- Territo, Paul R;
- Obenaus, Andre
Publication type:
Article
Characterization of brain metabolism, volume, and vasculature of the 5xFAD mouse model of Alzheimer's Disease across lifespan.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077201
By:
- Jullienne, Amandine;
- Szu, Jenny;
- Quan, Ryan;
- Trinh, Michelle V;
- Norouzi, Tannoz;
- Noarbe, Brenda P;
- Silvola, Rebecca;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Persohn, Scott C;
- Territo, Paul R;
- Obenaus, Andre
Publication type:
Article
Application of neurovascular uncoupling and whole brain network connectomics to assess the role of genetic and dietary risk factors in the LOAD2 mouse model.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065967
By:
- Silvola, Rebecca;
- Persohn, Scott C;
- Oblak, Adrian L;
- Lamb, Bruce T;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Howell, Gareth R;
- Sasner, Michael;
- Territo, Paul R
Publication type:
Article
Lifespan diffusion MRI reveals structural abnormalities in the 5xFAD model of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.062637
By:
- Noarbe, Brenda P;
- Jullienne, Amandine;
- Silvola, Rebecca;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Persohn, Scott C;
- Territo, Paul R;
- Obenaus, Andre;
- AD, MODEL
Publication type:
Article
Pharmacodynamics Assessment of Aducanumab in 5XFAD mice: A MODEL‐AD PTC Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.064606
By:
- Territo, Paul R;
- Quinney, Sara K;
- Masters, Andrea R;
- Haynes, Katy A;
- Cope, Zackery A;
- Little, Gabriela;
- Williams, Sean‐Paul;
- Meyer, Jill A;
- Peters, Jonathan;
- Figueiredo, Lucas;
- Persohn, Scott C;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Seyfried, Nicholas T.;
- Onos, Kristen D;
- Sasner, Michael;
- Howell, Gareth R;
- Carter, Gregory W;
- Oblak, Adrian L
Publication type:
Article
Cerebral perfusion and glucose metabolism profiling reveal special phenotypes in the hAPOE3, hAPOE4, Trem2 risk, and doubled risks mice.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.063682
By:
- Lin, Peter Bor‐Chian;
- Persohn, Scott C;
- Bedwell, Amanda A;
- Jiang, Lei;
- Eldridge, Kierra;
- Speedy, Rachael;
- Kotredes, Kevin P;
- Pandey, Ravi S;
- Williams, Harriet M;
- Oblak, Adrian L;
- Sasner, Michael;
- Howell, Gareth R;
- Carter, Gregory W;
- Lamb, Bruce T;
- Territo, Paul R
Publication type:
Article
Metabolic and Cerebrovascular Perturbations in the 5xFAD Mouse Model of Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.061565
By:
- Jullienne, Amandine;
- Szu, Jenny;
- Quan, Ryan;
- Silvola, Rebecca;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Persohn, Scott C;
- Obenaus, Andre;
- Territo, Paul R
Publication type:
Article
Neurovascular uncoupling of cerebral blood flow and glucose metabolism in APOE4, TREM2, and APOE4.TREM2 mice: Development of new models and analysis methods/novel assays and technologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041531
By:
- Territo, Paul R.;
- Lin, Peter B.;
- Persohn, Scott C.;
- Bedwell, Amanda A.;
- Eldridge, Kierra;
- Speedy, Rachael;
- Kotredes, Kevin P.;
- Pandey, Ravi S.;
- Oblak, Adrian L.;
- Sasner, Michael;
- Carter, Gregory W.;
- Lamb, Bruce T.;
- Howell, Gareth
Publication type:
Article
Pharmacokinetic, pharmacodynamic and transcriptomic analyses of verubecestat treatment in 5XFAD mice: Development of new models and analysis methods/novel assays and technologies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041491
By:
- Territo, Paul R.;
- Quinney, Sara K.;
- Biesdorf, Carla;
- Masters, Andrea R.;
- Onos, Kristen;
- Haynes, Leslie;
- Keezer, Kelly;
- Cope, Zackery A.;
- Meyer, Jill A.;
- Peters, Jonathan;
- Persohn, Scott C.;
- Figueiredo, Lucas;
- Bedwell, Amanda A.;
- Eldridge, Kierra;
- Speedy, Rachael;
- Sasner, Michael;
- Howell, Gareth;
- Carter, Gregory W.;
- Oblak, Adrian L.;
- Lamb, Bruce T.
Publication type:
Article
P4‐079: CRITICAL EVALUATION OF THE PHARMACOKINETICS OF VERUBECESTAT IN AGED 5XFAD MICE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1304, doi. 10.1016/j.jalz.2019.06.3739
By:
- Territo, Paul R.;
- Quinney, Sara K.;
- Biesdorf, Carla;
- Onos, Kristen;
- Haynes, Leslie;
- Keezer, Kelly J.;
- Meyer, Jill A.;
- Peters, Jonathan;
- Persohn, Scott C.;
- Bedwell, Amanda;
- Eldridge, Kierra;
- Speedy, Rachael;
- Sasner, Michael;
- Howell, Gareth;
- Williams, Harriet M.;
- Oblak, Adrian L.;
- Lamb, Bruce T.;
- Sukoff Rizzo, Stacey J.
Publication type:
Article
Inhibition of serum- and glucocorticoid-induced kinase 1 ameliorates hydrocephalus in preclinical models.
Published in:
Fluids & Barriers of the CNS, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12987-023-00461-0
By:
- Hochstetler, Alexandra;
- Smith, Hillary;
- Reed, Makenna;
- Hulme, Louise;
- Territo, Paul;
- Bedwell, Amanda;
- Persohn, Scott;
- Perrotti, Nicola;
- D'Antona, Lucia;
- Musumeci, Francesca;
- Schenone, Silvia;
- Blazer-Yost, Bonnie L.
Publication type:
Article
Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer's disease.
Published in:
Frontiers in Aging Neuroscience, 2023, p. 1, doi. 10.3389/fnagi.2023.1220036
By:
- Jullienne, Amandine;
- Szu, Jenny I.;
- Quan, Ryan;
- Trinh, Michelle V.;
- Norouzi, Tannoz;
- Noarbe, Brenda P.;
- Bedwell, Amanda A.;
- Eldridge, Kierra;
- Persohn, Scott C.;
- Territo, Paul R.;
- Obenaus, Andre
Publication type:
Article
Plcg2<sup>M28L</sup> Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.886575
By:
- Oblak, Adrian L.;
- Kotredes, Kevin P.;
- Pandey, Ravi S.;
- Reagan, Alaina M.;
- Ingraham, Cynthia;
- Perkins, Bridget;
- Lloyd, Christopher;
- Baker, Deborah;
- Lin, Peter B.;
- Soni, Disha M.;
- Tsai, Andy P.;
- Persohn, Scott A.;
- Bedwell, Amanda A.;
- Eldridge, Kierra;
- Speedy, Rachael;
- Meyer, Jill A.;
- Peters, Johnathan S.;
- Figueiredo, Lucas L.;
- Sasner, Michael;
- Territo, Paul R.
Publication type:
Article
The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2022, v. 42, n. 12, p. 2333, doi. 10.1177/0271678X221122644
By:
- Reagan, Alaina M;
- Christensen, Karen E;
- Graham, Leah C;
- Bedwell, Amanda A;
- Eldridge, Kierra;
- Speedy, Rachael;
- Figueiredo, Lucas L;
- Persohn, Scott C;
- Bottiglieri, Teodoro;
- Nho, Kwangsik;
- Sasner, Michael;
- Territo, Paul R;
- Rozen, Rima;
- Howell, Gareth R
Publication type:
Article
Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice.
Published in:
Science Translational Medicine, 2023, v. 15, n. 715, p. 1, doi. 10.1126/scitranslmed.adf8977
By:
- Liu, Yang;
- Reiken, Steven;
- Dridi, Haikel;
- Yuan, Qi;
- Mohammad, Khalid S.;
- Trivedi, Trupti;
- Miotto, Marco C.;
- Wedderburn-Pugh, Kaylee;
- Sittenfeld, Leah;
- Kerley, Ynez;
- Meyer, Jill A.;
- Peters, Jonathan S.;
- Persohn, Scott C.;
- Bedwell, Amanda A.;
- Figueiredo, Lucas L.;
- Suresh, Sukanya;
- She, Yun;
- Soni, Rajesh Kumar;
- Territo, Paul R.;
- Marks, Andrew R.
Publication type:
Article
1237-P: Generation of Targeted Nanoparticles for ß-Cell-Selective Delivery of Antioxidant Drugs.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1237-P
By:
- NOVAK, ALISSA;
- CHAKRAVARTHULA, TANMAYE NALLAN;
- CROWDER, JUSTIN;
- ALVES, NATHAN J.;
- BROICHHAGEN, JOHANNES;
- HODSON, DAVID;
- BEDWELL, AMANDA;
- LINNEMANN, AMELIA K.
Publication type:
Article

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