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Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35592-9
By:
- Chatila, Walid K.;
- Walch, Henry;
- Hechtman, Jaclyn F.;
- Moyer, Sydney M.;
- Sgambati, Valeria;
- Faleck, David M.;
- Srivastava, Amitabh;
- Tang, Laura;
- Benhamida, Jamal;
- Ismailgeci, Dorina;
- Campos, Carl;
- Wu, Fan;
- Chang, Qing;
- Vakiani, Efsevia;
- de Stanchina, Elisa;
- Weiser, Martin R.;
- Widmar, Maria;
- Yantiss, Rhonda K.;
- Shah, Manish A.;
- Bass, Adam J.
Publication type:
Article
Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 12, p. 5145, doi. 10.1172/JCI75200
By:
- Jihun Kim;
- Fox, Cameron;
- Shouyong Peng;
- Pusung, Mark;
- Pectasides, Eirini;
- Matthee, Eric;
- Yong Sang Hong;
- In-Cu Do;
- Jiryeon Jang;
- Thorner, Aaron R.;
- Van Hummelen, Paul;
- Rustgi, Anil K.;
- Kwok-Kin Wong;
- Zhongren Zhou;
- Ping Tang;
- Kyoung-Mee Kim;
- Jeeyun Lee;
- Bass, Adam J.
Publication type:
Article
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 4, p. 1636, doi. 10.1172/JCI71545
By:
- Hideo Watanabe;
- Qiuping Ma;
- Shouyong Peng;
- Adelmant, Guillaume;
- Swain, Danielle;
- Wenyu Song;
- Fox, Cameron;
- Francis, Joshua M.;
- Chandra Sekhar Pedamallu;
- DeLuca, David S.;
- Brooks, Angela N.;
- Su Wang;
- Jianwen Que;
- Rustgi, Anil K.;
- Kwok-kin Wong;
- Ligon, Keith L.;
- Liu, X. Shirley;
- Marto, Jarrod A.;
- Meyerson, Matthew;
- Bass, Adam J.
Publication type:
Article
A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27055-4
By:
- Liu, Yanli;
- Wu, Zhong;
- Zhou, Jin;
- Ramadurai, Dinesh K. A.;
- Mortenson, Katelyn L.;
- Aguilera-Jimenez, Estrella;
- Yan, Yifei;
- Yang, Xiaojun;
- Taylor, Alison M.;
- Varley, Katherine E.;
- Gertz, Jason;
- Choi, Peter S.;
- Cherniack, Andrew D.;
- Chen, Xingdong;
- Bass, Adam J.;
- Bailey, Swneke D.;
- Zhang, Xiaoyang
Publication type:
Article
Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25700-6
By:
- Dang, Fabin;
- Nie, Li;
- Zhou, Jin;
- Shimizu, Kouhei;
- Chu, Chen;
- Wu, Zhong;
- Fassl, Anne;
- Ke, Shizhong;
- Wang, Yuangao;
- Zhang, Jinfang;
- Zhang, Tao;
- Tu, Zhenbo;
- Inuzuka, Hiroyuki;
- Sicinski, Piotr;
- Bass, Adam J.;
- Wei, Wenyi
Publication type:
Article
Paired exome analysis of Barrett's esophagus and adenocarcinoma.
Published in:
Nature Genetics, 2015, v. 47, n. 9, p. 1047, doi. 10.1038/ng.3343
By:
- Taylor-Weiner, Amaro;
- Peng, Shouyong;
- Stojanov, Petar;
- Lin, Jules;
- Bass, Adam J;
- Stewart, Chip;
- Seepo, Sara;
- Odze, Robert D;
- Nason, Katie S;
- Stachler, Matthew D;
- Carter, Scott L;
- Lander, Eric S;
- Leshchiner, Ignaty;
- Lawrence, Michael S;
- McKenna, Aaron;
- Chang, Andrew C;
- Agoston, Agoston T;
- Beer, David G;
- Loda, Massimo;
- Davison, Jon M
Publication type:
Article
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Published in:
Nature Genetics, 2011, v. 43, n. 10, p. 964, doi. 10.1038/ng.936
By:
- Bass, Adam J;
- Lawrence, Michael S;
- Brace, Lear E;
- Ramos, Alex H;
- Drier, Yotam;
- Cibulskis, Kristian;
- Sougnez, Carrie;
- Voet, Douglas;
- Saksena, Gordon;
- Sivachenko, Andrey;
- Jing, Rui;
- Parkin, Melissa;
- Pugh, Trevor;
- Verhaak, Roel G;
- Stransky, Nicolas;
- Boutin, Adam T;
- Barretina, Jordi;
- Solit, David B;
- Vakiani, Evi;
- Shao, Wenlin
Publication type:
Article
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Published in:
Nature Genetics, 2011, v. 43, n. 9, p. 869, doi. 10.1038/ng.890
By:
- Locasale, Jason W.;
- Grassian, Alexandra R.;
- Melman, Tamar;
- Lyssiotis, Costas A.;
- Mattaini, Katherine R.;
- Bass, Adam J.;
- Heffron, Gregory;
- Metallo, Christian M.;
- Muranen, Taru;
- Sharfi, Hadar;
- Sasaki, Atsuo T.;
- Anastasiou, Dimitrios;
- Mullarky, Edouard;
- Vokes, Natalie I.;
- Sasaki, Mika;
- Beroukhim, Rameen;
- Stephanopoulos, Gregory;
- Ligon, Azra H.;
- Meyerson, Matthew;
- Richardson, Andrea L.
Publication type:
Article
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
Published in:
Nature Genetics, 2009, v. 41, n. 11, p. 1238, doi. 10.1038/ng.465
By:
- Bass, Adam J.;
- Watanabe, Hideo;
- Mermel, Craig H.;
- Soyoung Yu;
- Perner, Sven;
- Verhaak, Roel G.;
- So Young Kim;
- Wardwell, Leslie;
- Tamayo, Pablo;
- Gat-Viks, Irit;
- Ramos, Alex H.;
- Woo, Michele S.;
- Weir, Barbara A.;
- Getz, Gad;
- Beroukhim, Rameen;
- O'Kelly, Michael;
- Dutt, Amit;
- Rozenblatt-Rosen, Orit;
- Dziunycz, Piotr;
- Komisarof, Justin
Publication type:
Article
Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab.
Published in:
Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-141
By:
- Jeonghee Cho;
- Bass, Adam J.;
- Lawrence, Michael S.;
- Cibulskis, Kristian;
- Ahye Cho;
- Shi-Nai Lee;
- Yamauchi, Mai;
- Wagle, Nikhil;
- Pochanard, Panisa;
- Nayoung Kim;
- Park, Angela K. J.;
- Jonghwa Won;
- Hyung-Suk Hur;
- Greulich, Heidi;
- Ogino, Shuji;
- Sougnez, Carrie;
- Voet, Douglas;
- Tabernero, Josep;
- Jimenez, Jose;
- Baselga, Jose
Publication type:
Article
Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review.
Published in:
Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-135
By:
- Imamura, Yu;
- Lochhead, Paul;
- Yamauchi, Mai;
- Kuchiba, Aya;
- Zhi Rong Qian;
- Xiaoyun Liao;
- Nishihara, Reiko;
- Seungyoun Jung;
- Wu, Kana;
- Nosho, Katsuhiko;
- Wang, Yaoyu E.;
- Shouyong Peng;
- Bass, Adam J.;
- Haigis, Kevin M.;
- Meyerhardt, Jeffrey A.;
- Chan, Andrew T.;
- Fuchs, Charles S.;
- Ogino, Shuji
Publication type:
Article
Comparative transcriptomes of adenocarcinomas and squamous cell carcinomas reveal molecular similarities that span classical anatomic boundaries.
Published in:
PLoS Genetics, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pgen.1006938
By:
- Lin, Eric W.;
- Karakasheva, Tatiana A.;
- Lee, Dong-Jin;
- Lee, Ju-Seog;
- Long, Qi;
- Bass, Adam J.;
- Wong, Kwok K.;
- Rustgi, Anil K.
Publication type:
Article
Fine needle aspirate flow cytometric phenotyping characterizes immunosuppressive nature of the mesothelioma microenvironment.
Published in:
Scientific Reports, 2016, p. 31745, doi. 10.1038/srep31745
By:
- Lizotte, Patrick H.;
- Jones, Robert E.;
- Keogh, Lauren;
- Ivanova, Elena;
- Liu, Hongye;
- Awad, Mark M.;
- Hammerman, Peter S.;
- Gill, Ritu R.;
- Richards, William G.;
- Barbie, David A.;
- Bass, Adam J.;
- Bueno, Raphael;
- English, Jessie M.;
- Bittinger, Mark;
- Wong, Kwok-Kin
Publication type:
Article
Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer?
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2018.03107
By:
- Goedegebuure, Ruben S. A.;
- de Klerk, Leonie K.;
- Bass, Adam J.;
- Derks, Sarah;
- Thijssen, Victor L. J. L.
Publication type:
Article
Genomic signatures of past and present chromosomal instability in Barrett's esophagus and early esophageal adenocarcinoma.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41805-6
By:
- Bao, Chunyang;
- Tourdot, Richard W.;
- Brunette, Gregory J.;
- Stewart, Chip;
- Sun, Lili;
- Baba, Hideo;
- Watanabe, Masayuki;
- Agoston, Agoston T.;
- Jajoo, Kunal;
- Davison, Jon M.;
- Nason, Katie S.;
- Getz, Gad;
- Wang, Kenneth K.;
- Imamura, Yu;
- Odze, Robert;
- Bass, Adam J.;
- Stachler, Matthew D.;
- Zhang, Cheng-Zhong
Publication type:
Article
Src Mutation Induces Acquired Lapatinib Resistance in ERBB2-Amplified Human Gastroesophageal Adenocarcinoma Models.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109440
By:
- Hong, Yong Sang;
- Kim, Jihun;
- Pectasides, Eirini;
- Fox, Cameron;
- Hong, Seung-Woo;
- Ma, Qiuping;
- Wong, Gabrielle S.;
- Peng, Shouyong;
- Stachler, Matthew D.;
- Thorner, Aaron R.;
- Van Hummelen, Paul;
- Bass, Adam J.
Publication type:
Article
Colorectal Cancers from Distinct Ancestral Populations Show Variations in <i>BRAF</i> Mutation Frequency.
Published in:
PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074950
By:
- Hanna, Megan C.;
- Go, Christina;
- Roden, Christine;
- Jones, Robert T.;
- Pochanard, Panisa;
- Javed, Ahmed Yasir;
- Javed, Awais;
- Mondal, Chandrani;
- Palescandolo, Emanuele;
- Van Hummelen, Paul;
- Hatton, Charles;
- Bass, Adam J.;
- Chun, Sung Min;
- Na, Deuk Chae;
- Kim, Tae-Im;
- Jang, Se Jin;
- Osarogiagbon, Raymond U.;
- Hahn, William C.;
- Meyerson, Matthew;
- Garraway, Levi A.
Publication type:
Article
Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09179-w
By:
- Qie, Shuo;
- Yoshida, Akihiro;
- Parnham, Stuart;
- Oleinik, Natalia;
- Beeson, Gyda C.;
- Beeson, Craig C.;
- Ogretmen, Besim;
- Bass, Adam J.;
- Wong, Kwok-Kin;
- Rustgi, Anil K.;
- Diehl, J. Alan
Publication type:
Article
Molecular profiles of response to neoadjuvant chemoradiotherapy in oesophageal cancers to develop personalized treatment strategies.
Published in:
Molecular Oncology, 2021, v. 15, n. 4, p. 901, doi. 10.1002/1878-0261.12907
By:
- Klerk, Leonie K.;
- Goedegebuure, Ruben S. A.;
- Grieken, Nicole C. T.;
- Sandick, Johanna W.;
- Cats, Annemieke;
- Stiekema, Jurrien;
- Kaaij, Rosa T.;
- Farina Sarasqueta, Arantza;
- Engeland, Manon;
- Jacobs, Maarten A. J. M.;
- Wanrooij, Roy L. J.;
- Peet, Donald L.;
- Thorner, Aaron R.;
- Verheul, Henk M. W.;
- Thijssen, Victor L. J. L.;
- Bass, Adam J.;
- Derks, Sarah
Publication type:
Article
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity.
Published in:
Nature, 2008, v. 455, n. 7212, p. 547, doi. 10.1038/nature07179
By:
- Firestein, Ron;
- Bass, Adam J.;
- So Young Kim;
- Dunn, Ian F.;
- Silver, Serena J.;
- Guney, Isil;
- Freed, Ellen;
- Ligon, Azra H.;
- Vena, Natalie;
- Ogino, Shuji;
- Chheda, Milan G.;
- Tamayo, Pablo;
- Finn, Stephen;
- Shrestha, Yashaswi;
- Boehm, Jesse S.;
- Jain, Supriya;
- Bojarski, Emeric;
- Mermel, Craig;
- Barretina, Jordi;
- Chan, Jennifer A.
Publication type:
Article
Family history and survival after colorectal cancer diagnosis.
Published in:
2008
By:
- Bass, Adam J.;
- Meyerhardt, Jeffrey A.;
- Chan, Jennifer A.;
- Giovannucci, Edward L.;
- Fuchs, Charles S.
Publication type:
journal article
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
Published in:
2017
By:
- Giroux, Véronique;
- Lento, Ashley A.;
- Islam, Mirazul;
- Pitarresi, Jason R.;
- Kharbanda, Akriti;
- Hamilton, Kathryn E.;
- Whelan, Kelly A.;
- Long, Apple;
- Rhoades, Ben;
- Qiaosi Tang;
- Hiroshi Nakagawa;
- Lengner, Christopher J.;
- Bass, Adam J.;
- Wileyto, E. Paul;
- Klein-Szanto, Andres J.;
- Wang, Timothy C.;
- Rustgi, Anil K.;
- Tang, Qiaosi;
- Nakagawa, Hiroshi
Publication type:
journal article
CDK4/6 or MAPK blockade enhances efficacy of EGFR inhibition in oesophageal squamous cell carcinoma.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 13897, doi. 10.1038/ncomms13897
By:
- Zhou, Jin;
- Wu, Zhong;
- Wong, Gabrielle;
- Pectasides, Eirini;
- Nagaraja, Ankur;
- Stachler, Matthew;
- Zhang, Haikuo;
- Chen, Ting;
- Zhang, Haisheng;
- Liu, Jie Bin;
- Xu, Xinsen;
- Sicinska, Ewa;
- Sanchez-Vega, Francisco;
- Rustgi, Anil K.;
- Diehl, J. Alan;
- Wong, Kwok-Kin;
- Bass, Adam J.
Publication type:
Article
RHOA<sup>L57V</sup> drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling.
Published in:
Science Signaling, 2023, v. 16, n. 816, p. 1, doi. 10.1126/scisignal.adg5289
By:
- Schaefer, Antje;
- Hodge, Richard G.;
- Zhang, Haisheng;
- Hobbs, G. Aaron;
- Dilly, Julien;
- Huynh, Minh V.;
- Goodwin, Craig M.;
- Zhang, Feifei;
- Diehl, J. Nathaniel;
- Pierobon, Mariaelena;
- Baldelli, Elisa;
- Javaid, Sehrish;
- Guthrie, Karson;
- Rashid, Naim U.;
- Petricoin, Emanuel F.;
- Cox, Adrienne D.;
- Hahn, William C.;
- Aguirre, Andrew J.;
- Bass, Adam J.;
- Der, Channing J.
Publication type:
Article
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01500-9
By:
- Mitsuteru Natsuizaka;
- Whelan, Kelly A.;
- Shingo Kagawa;
- Koji Tanaka;
- Giroux, Veronique;
- Chandramouleeswaran, Prasanna M.;
- Long, Apple;
- Sahu, Varun;
- Darling, Douglas S.;
- Jianwen Que;
- Yizeng Yang;
- Katz, Jonathan P.;
- Wileyto, E. Paul;
- Basu, Devraj;
- Yoshiaki Kita;
- Shoji Natsugoe;
- Seiji Naganuma;
- Klein-Szanto, Andres J.;
- Diehl, J. Alan;
- Bass, Adam J.
Publication type:
Article
Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients.
Published in:
PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0176045
By:
- Schumacher, Steven E.;
- Shim, Byoung Yong;
- Corso, Giovanni;
- Ryu, Min-Hee;
- Kang, Yoon-Koo;
- Roviello, Franco;
- Saksena, Gordon;
- Peng, Shouyong;
- Shivdasani, Ramesh A.;
- Bass, Adam J.;
- Beroukhim, Rameen
Publication type:
Article

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