Found: 3

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  • Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05190-9
    By:
    • Li, Xiaodun;
    • Francies, Hayley E.;
    • Secrier, Maria;
    • Perner, Juliane;
    • Miremadi, Ahmad;
    • Galeano-Dalmau, Núria;
    • Barendt, William J.;
    • Letchford, Laura;
    • Leyden, Genevieve M.;
    • Goffin, Emma K.;
    • Barthorpe, Andrew;
    • Lightfoot, Howard;
    • Chen, Elisabeth;
    • Gilbert, James;
    • Noorani, Ayesha;
    • Devonshire, Ginny;
    • Bower, Lawrence;
    • Grantham, Amber;
    • MacRae, Shona;
    • Grehan, Nicola
    Publication type:
    Article

  • Integrated cross-study datasets of genetic dependencies in cancer.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21898-7
    By:
    • Pacini, Clare;
    • Dempster, Joshua M.;
    • Boyle, Isabella;
    • Gonçalves, Emanuel;
    • Najgebauer, Hanna;
    • Karakoc, Emre;
    • van der Meer, Dieudonne;
    • Barthorpe, Andrew;
    • Lightfoot, Howard;
    • Jaaks, Patricia;
    • McFarland, James M.;
    • Garnett, Mathew J.;
    • Tsherniak, Aviad;
    • Iorio, Francesco
    Publication type:
    Article

  • Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens.

    Published in:
    Molecular Systems Biology, 2020, v. 16, n. 7, p. 1, doi. 10.15252/msb.20199405
    By:
    • Gonçalves, Emanuel;
    • Segura‐Cabrera, Aldo;
    • Pacini, Clare;
    • Picco, Gabriele;
    • Behan, Fiona M;
    • Jaaks, Patricia;
    • Coker, Elizabeth A;
    • Meer, Donny;
    • Barthorpe, Andrew;
    • Lightfoot, Howard;
    • Mironenko, Tatiana;
    • Beck, Alexandra;
    • Richardson, Laura;
    • Yang, Wanjuan;
    • Lleshi, Ermira;
    • Hall, James;
    • Tolley, Charlotte;
    • Hall, Caitlin;
    • Mali, Iman;
    • Thomas, Frances
    Publication type:
    Article