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Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes.
Published in:
Cellular Microbiology, 2019, v. 21, n. 7, p. N.PAG, doi. 10.1111/cmi.13030
By:
- Healer, Julie;
- Wong, Wilson;
- Thompson, Jennifer K.;
- He, Wengqiang;
- Birkinshaw, Richard W.;
- Miura, Kazutoyo;
- Long, Carol A.;
- Soroka, Vladislav;
- Søgaard, Teit Max Moscote;
- Jørgensen, Thomas;
- Jongh, Willem A.;
- Weir, Christopher;
- Svahn, Ella;
- Czabotar, Peter E.;
- Tham, Wai‐Hong;
- Mueller, Ivo;
- Barlow, Paul N.;
- Cowman, Alan F.
Publication type:
Article
The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation.
Published in:
Journal of Molecular Recognition, 2011, v. 24, n. 2, p. 245, doi. 10.1002/jmr.1042
By:
- Popovic, Matija;
- Bella, Juraj;
- Zlatev, Ventsislav;
- Hodnik, Vesna;
- Anderluh, Gregor;
- Barlow, Paul N.;
- Pintar, Alessandro;
- Pongor, Sándor
Publication type:
Article
Structural basis for engagement by complement factor H of C3b on a self surface.
Published in:
Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 463, doi. 10.1038/nsmb.2018
By:
- Morgan, Hugh P.;
- Schmidt, Christoph Q.;
- Guariento, Mara;
- Blaum, Bärbel S.;
- Gillespie, Dominic;
- Herbert, Andrew P.;
- Kavanagh, David;
- Mertens, Haydyn D. T.;
- Svergun, Dmitri I.;
- Johansson, Conny M.;
- Uhrín, Dušan;
- Barlow, Paul N.;
- Hannan, Jonathan P.
Publication type:
Article
Lack of Evidence from Studies of Soluble Protein Fragments that Knops Blood Group Polymorphisms in Complement Receptor-Type 1 Are Driven by Malaria.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034820
By:
- Tetteh-Quarcoo, Patience B.;
- Schmidt, Christoph Q.;
- Wai-Hong Tham;
- Hauhart, Richard;
- Mertens, Haydyn D. T.;
- Rowe, Arthur;
- Atkinson, John P.;
- Cowman, Alan F.;
- Rowe, J. Alexandra;
- Barlow, Paul N.
Publication type:
Article
Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0032187
By:
- Morgan, Hugh P.;
- Mertens, Haydyn D. T.;
- Guariento, Mara;
- Schmidt, Christoph Q.;
- Soares, Dinesh C.;
- Svergun, Dmitri I.;
- Herbert, Andrew P.;
- Barlow, Paul N.;
- Hannan, Jonathan P.
Publication type:
Article
Structural Models of Human eEF1A1 and eEF1A2 Reveal Two Distinct Surface Clusters of Sequence Variation and Potential Differences in Phosphorylation.
Published in:
PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006315
By:
- Soares, Dinesh C.;
- Barlow, Paul N.;
- Newbery, Helen J.;
- Porteous, David J.;
- Abbott, Catherine M.
Publication type:
Article
Opportunities for New Therapies Based on the Natural Regulators of Complement Activation.
Published in:
Annals of the New York Academy of Sciences, 2005, v. 1056, n. 1, p. 176, doi. 10.1196/annals.1352.033
By:
- BROOK, EVE;
- HERBERT, ANDREW P.;
- JENKINS, HUW T.;
- SOARES, DINESH C.;
- BARLOW, PAUL N.
Publication type:
Article
Letter to the Editor: 1H, 15N and 13C resonance assignments of complement control protein module pair 2–3 from the C4b-binding site of complement receptor type 1.
Published in:
Journal of Biomolecular NMR, 2004, v. 30, n. 2, p. 227, doi. 10.1023/B:JNMR.0000048853.72652.9a
By:
- Black, Gordon;
- Wenzler, Michael;
- Xuefeng Wang;
- Krych-Goldberg, Malgorzata;
- Atkinson, John P.;
- Barlow, Paul N.
Publication type:
Article
Letter to the Editor: 1H, 15N and 13C resonance assignments of the C345C domain of the complement component C5.
Published in:
Journal of Biomolecular NMR, 2004, v. 29, n. 2, p. 217, doi. 10.1023/B:JNMR.0000019243.25787.15
By:
- Bramham, Janice;
- Rance, Mark;
- Chuong-Thu Thai;
- Uhrín, Dušan;
- Assa-Munt, Nuria;
- Ogata, Ronald T.;
- Barlow, Paul N.
Publication type:
Article
Structure and flexibility of the multiple domain proteins that regulate complement activation.
Published in:
Immunological Reviews, 2001, v. 180, n. 1, p. 146, doi. 10.1034/j.1600-065x.2001.1800113.x
By:
- Kirkitadze, Marina D.;
- Barlow, Paul N.
Publication type:
Article
A supernumerary synthetic chromosome in Komagataella phaffii as a repository for extraneous genetic material.
Published in:
Microbial Cell Factories, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12934-023-02262-4
By:
- Abramczyk, Dariusz;
- del Carmen Sanchez Olmos, Maria;
- Rojas, Adan Andres Ramirez;
- Schindler, Daniel;
- Robertson, Daniel;
- McColm, Stephen;
- Marston, Adele L.;
- Barlow, Paul N.
Publication type:
Article
Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.
Published in:
2019
By:
- Smith-Jackson, Kate;
- Yi Yang;
- Denton, Harriet;
- Pappworth, Isabel Y.;
- Cooke, Katie;
- Barlow, Paul N.;
- Atkinson, John P.;
- Liszewski, M. Kathryn;
- Pickering, Matthew C.;
- Kavanagh, David;
- Cook, H. Terence;
- Marchbank, Kevin J.;
- Yang, Yi
Publication type:
journal article
Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.
Published in:
Frontiers in Immunology, 2021, v. 12, p. N.PAG, doi. 10.3389/fimmu.2021.681098
By:
- Kerr, Heather;
- Herbert, Andrew P.;
- Makou, Elisavet;
- Abramczyk, Dariusz;
- Malik, Talat H.;
- Lomax-Browne, Hannah;
- Yang, Yi;
- Pappworth, Isabel Y.;
- Denton, Harriet;
- Richards, Anna;
- Marchbank, Kevin J.;
- Pickering, Matthew C.;
- Barlow, Paul N.
Publication type:
Article
Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes.
Published in:
PLoS Pathogens, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.ppat.1004670
By:
- Weiss, Greta E.;
- Gilson, Paul R.;
- Taechalertpaisarn, Tana;
- Tham, Wai-Hong;
- de Jong, Nienke W. M.;
- Harvey, Katherine L.;
- Fowkes, Freya J. I.;
- Barlow, Paul N.;
- Rayner, Julian C.;
- Wright, Gavin J.;
- Cowman, Alan F.;
- Crabb, Brendan S.
Publication type:
Article
Creating functional sophistication from simple protein building blocks, exemplified by factor H and the regulators of complement activation.
Published in:
Biochemical Society Transactions, 2015, v. 43, n. 5, p. 812, doi. 10.1042/BST20150074
By:
- Makou, Elisavet;
- Herbert, Andrew P.;
- Barlow, Paul N.
Publication type:
Article
Letter to the Editor: Resonance assignments of the central complement control protein module pair of human decay accelerating factor.
Published in:
Journal of Biomolecular NMR, 2002, v. 23, n. 2, p. 167, doi. 10.1023/a:1016362923187
By:
- Uhrí;nová, Stanislava;
- Lin, Feng;
- Duŝan Uhrín;
- Medof, M. Edward;
- Barlow, Paul N.
Publication type:
Article
Letter to the Editor: 1H, 15N and 13C resonance assignments of the N-terminal region of calponin.
Published in:
Journal of Biomolecular NMR, 2001, v. 19, n. 2, p. 189, doi. 10.1023/A:1008392206407
By:
- Bramham, Janice;
- Smith, Brian O.;
- Uhrín, Dušan;
- Barlow, Paul N.;
- Winder, Steven J.
Publication type:
Article
Simultaneous CT-13C and VT-15N chemical shift labelling: Application to 3D NOESY-CH3NH and 3D 13C,15N HSQC-NOESY-CH3NH.
Published in:
Journal of Biomolecular NMR, 2000, v. 18, n. 3, p. 253, doi. 10.1023/a:1026550629595
By:
- Uhrín, Dušan;
- Bramham, Janice;
- Winder, Steven J.;
- Barlow, Paul N.
Publication type:
Article
MDM4 binds ligands via a mechanism in which disordered regions become structured
Published in:
FEBS Letters, 2010, v. 584, n. 14, p. 3035, doi. 10.1016/j.febslet.2010.05.058
By:
- Sanchez, Maria C.;
- Renshaw, Jonathan G.;
- Davies, Gareth;
- Barlow, Paul N.;
- Vogtherr, Martin
Publication type:
Article
Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus).
Published in:
Protein Science: A Publication of the Protein Society, 2011, v. 20, n. 12, p. 2102, doi. 10.1002/pro.738
By:
- Pechtl, Isabell C.;
- Neely, Robert K.;
- Dryden, David T.F.;
- Jones, Anita C.;
- Barlow, Paul N.
Publication type:
Article
Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.
Published in:
Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 5, p. 1238, doi. 10.1110/ps.03582704
By:
- O'Leary, Joanne M.;
- Bromek, Krystyna;
- Black, Gordon M.;
- Uhrinova, Stanislava;
- Schmitz, Christian;
- Wang, Xuefeng;
- Krych, Malgorzata;
- Atkinson, John P.;
- Uhrin, Dusan;
- Barlow, Paul N.
Publication type:
Article
Synthesis, Structural and Biological Studies of Ubiquitin Mutants Containing (2 S, 4 S)-5-Fluoroleucine Residues Strategically Placed in the Hydrophobic Core.
Published in:
ChemBioChem, 2003, v. 4, n. 9, p. 894, doi. 10.1002/cbic.200300699
By:
- Alexeev, Dmitriy;
- Barlow, Paul N.;
- Bury, Stella M.;
- Charrier, Jean-Damien;
- Cooper, Alan;
- Hadfield, David;
- Jamieson, Craig;
- Kelly, Sharon M.;
- Layfield, Robert;
- Mayer, R. John;
- McSparron, Helen;
- Price, Nicholas C.;
- Ramage, Robert;
- Sawyer, Lindsay;
- Starkmann, Bernard A.;
- Uhrin, Dusan;
- Wilken, Jill;
- Young, Douglas W.
Publication type:
Article
Decoding the components of dynamics in three-domain proteins.
Published in:
Journal of Computational Chemistry, 2014, v. 35, n. 7, p. 518, doi. 10.1002/jcc.23510
By:
- Maciejewski, Mateusz;
- Barlow, Paul N.;
- Tjandra, Nico
Publication type:
Article
Large-scale modelling as a route to multiple surface comparisons of the CCP module family.
Published in:
PEDS: Protein Engineering, Design & Selection, 2005, v. 18, n. 8, p. 379, doi. 10.1093/protein/gzi039
By:
- Dinesh C. Soares;
- Dietlind L. Gerloff;
- Neil R. Syme;
- Andrew F.W. Coulson;
- John Parkinson;
- Paul N. Barlow
Publication type:
Article

Found: 24

Neutralising antibodies block the function of Rh5/Ripr/CyRPA complex during invasion of Plasmodium falciparum into human erythrocytes.

The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation.

Structural basis for engagement by complement factor H of C3b on a self surface.

Lack of Evidence from Studies of Soluble Protein Fragments that Knops Blood Group Polymorphisms in Complement Receptor-Type 1 Are Driven by Malaria.

Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).

Structural Models of Human eEF1A1 and eEF1A2 Reveal Two Distinct Surface Clusters of Sequence Variation and Potential Differences in Phosphorylation.

Opportunities for New Therapies Based on the Natural Regulators of Complement Activation.

Letter to the Editor: <sup>1</sup>H, <sup>15</sup>N and <sup>13</sup>C resonance assignments of complement control protein module pair 2–3 from the C4b-binding site of complement receptor type 1.

Letter to the Editor: <sup>1</sup>H, <sup>15</sup>N and <sup>13</sup>C resonance assignments of the C345C domain of the complement component C5.

Structure and flexibility of the multiple domain proteins that regulate complement activation.

A supernumerary synthetic chromosome in Komagataella phaffii as a repository for extraneous genetic material.

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.

Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes.

Creating functional sophistication from simple protein building blocks, exemplified by factor H and the regulators of complement activation.

Letter to the Editor: Resonance assignments of the central complement control protein module pair of human decay accelerating factor.

Letter to the Editor: 1H, 15N and 13C resonance assignments of the N-terminal region of calponin.

Simultaneous CT-13C and VT-15N chemical shift labelling: Application to 3D NOESY-CH3NH and 3D 13C,15N HSQC-NOESY-CH3NH.

MDM4 binds ligands via a mechanism in which disordered regions become structured

Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus).

Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.

Synthesis, Structural and Biological Studies of Ubiquitin Mutants Containing (2 S, 4 S)-5-Fluoroleucine Residues Strategically Placed in the Hydrophobic Core.

Decoding the components of dynamics in three-domain proteins.

Large-scale modelling as a route to multiple surface comparisons of the CCP module family.