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Liquid biopsy, a paradigm shift in oncology: what interventional radiologists should know.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists.
- Published in:
- Oncogene, 1999, v. 18, n. 37, p. 5221, doi. 10.1038/sj.onc.1202899
- By:
- Publication type:
- Article
Loss of the exon encoding the juxtamembrane domain is essential for the oncogenic activation of TPR-MET.
- Published in:
- Oncogene, 1999, v. 18, n. 29, p. 4275, doi. 10.1038/sj.onc.1202791
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- Publication type:
- Article
Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis.
- Published in:
- Oncogene, 1999, v. 18, n. 5, p. 1139, doi. 10.1038/sj.onc.1202607
- By:
- Publication type:
- Article
Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
- Published in:
- Oncogene, 1997, v. 15, n. 25, p. 3103, doi. 10.1038/sj.onc.1201561
- By:
- Publication type:
- Article
Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family.
- Published in:
- International Journal of Cancer, 1999, v. 82, n. 5, p. 640, doi. 10.1002/(SICI)1097-0215(19990827)82:5<640::AID-IJC4>3.0.CO;2-6
- By:
- Publication type:
- Article
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT).
- Published in:
- Cell Death & Disease, 2023, v. 14, n. 2, p. 1, doi. 10.1038/s41419-023-05640-3
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- Publication type:
- Article
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 10, p. 1, doi. 10.1038/s41419-020-03131-3
- By:
- Publication type:
- Article
Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.
- Published in:
- 2018
- By:
- Publication type:
- Correction Notice
Oncogenes and angiogenesis: a way to personalize anti-angiogenic therapy?
- Published in:
- Cellular & Molecular Life Sciences, 2013, v. 70, n. 21, p. 4131, doi. 10.1007/s00018-013-1331-3
- By:
- Publication type:
- Article
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
- Published in:
- FASEB Journal, 2015, v. 29, n. 2, p. 464, doi. 10.1096/fj.14-262303
- By:
- Publication type:
- Article
Colorectal cancer: Mutations in a signalling pathway.
- Published in:
- Nature, 2005, v. 436, n. 7052, p. 792, doi. 10.1038/436792a
- By:
- Publication type:
- Article
RAF/RAS oncogenes and mismatch-repair status.
- Published in:
- Nature, 2002, v. 418, n. 6901, p. 934, doi. 10.1038/418934a
- By:
- Publication type:
- Article
Anti-EGFR Rechallenge in Patients With Refractory ctDNA RAS/BRAF wt Metastatic Colorectal Cancer: A Nonrandomized Controlled Trial.
- Published in:
- JAMA Network Open, 2024, v. 7, n. 4, p. e245635, doi. 10.1001/jamanetworkopen.2024.5635
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- Publication type:
- Article
Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance.
- Published in:
- Nature Communications, 2017, v. 8, n. 6, p. 1, doi. 10.1038/ncomms15617
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- Publication type:
- Article
Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers.
- Published in:
- Nature Communications, 2015, v. 6, n. 9, p. 8305, doi. 10.1038/ncomms9305
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- Publication type:
- Article
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
- Published in:
- Nature Communications, 2015, v. 6, n. 4, p. 7002, doi. 10.1038/ncomms8002
- By:
- Publication type:
- Article
High-dose vitamin C enhances cancer immunotherapy.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 532, p. 1, doi. 10.1126/scitranslmed.aay8707
- By:
- Publication type:
- Article
Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy- Refractory Metastatic Colorectal Cancer Treated With Cetuximab.
- Published in:
- JAMA: Journal of the American Medical Association, 2010, v. 304, n. 16, p. 1812, doi. 10.1001/jama.2010.1535
- By:
- Publication type:
- Article
Evolving neoantigen profiles in colorectal cancers with DNA repair defects.
- Published in:
- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0654-6
- By:
- Publication type:
- Article
Inactivation of DNA repair—prospects for boosting cancer immune surveillance.
- Published in:
- Genome Medicine, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13073-018-0603-9
- By:
- Publication type:
- Article
The prognostic IDH1<sup> R132</sup> mutation is associated with reduced NADP<sup>+</sup>-dependent IDH activity in glioblastoma.
- Published in:
- Acta Neuropathologica, 2010, v. 119, n. 4, p. 487, doi. 10.1007/s00401-010-0645-6
- By:
- Publication type:
- Article
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.
- Published in:
- Nature, 2012, v. 483, n. 7387, p. 100, doi. 10.1038/nature10868
- By:
- Publication type:
- Article
Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2009, v. 101, n. 19, p. 1308, doi. 10.1093/jnci/djp280
- By:
- Publication type:
- Article
Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions.
- Published in:
- EMBO Molecular Medicine, 2017, v. 9, n. 3, p. 293, doi. 10.15252/emmm.201606773
- By:
- Publication type:
- Article
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer.
- Published in:
- Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-023-01275-3
- By:
- Publication type:
- Article
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02465-4
- By:
- Publication type:
- Article
Zurletrectinib is a next-generation TRK inhibitor with strong intracranial activity against NTRK fusion-positive tumours with on-target resistance to first-generation agents.
- Published in:
- British Journal of Cancer, 2024, v. 131, n. 3, p. 601, doi. 10.1038/s41416-024-02760-1
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- Publication type:
- Article
Liquid biopsies to monitor and direct cancer treatment in colorectal cancer.
- Published in:
- 2022
- By:
- Publication type:
- journal article
373. Use of Lentiviral and Adeno-Associated Vectors for Targeted Gene Inactivation in Human Cancer Cells
- Published in:
- 2005
- By:
- Publication type:
- Abstract
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Mutational signatures of colorectal cancers according to distinct computational workflows.
- Published in:
- Briefings in Bioinformatics, 2024, v. 25, n. 4, p. 1, doi. 10.1093/bib/bbae249
- By:
- Publication type:
- Article
Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04506-z
- By:
- Publication type:
- Article
Transcriptome‐wide gene expression outlier analysis pinpoints therapeutic vulnerabilities in colorectal cancer.
- Published in:
- Molecular Oncology, 2024, v. 18, n. 6, p. 1460, doi. 10.1002/1878-0261.13622
- By:
- Publication type:
- Article
Preclinical efficacy of carfilzomib in BRAF‐mutant colorectal cancer models.
- Published in:
- Molecular Oncology, 2024, v. 18, n. 6, p. 1552, doi. 10.1002/1878-0261.13595
- By:
- Publication type:
- Article
Dual VEGFA/BRAF targeting boosts PD‐1 blockade in melanoma through GM‐CSF‐mediated infiltration of M1 macrophages.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 8, p. 1474, doi. 10.1002/1878-0261.13450
- By:
- Publication type:
- Article
Towards a cancer mission in Horizon Europe: recommendations.
- Published in:
- Molecular Oncology, 2020, v. 14, n. 8, p. 1589, doi. 10.1002/1878-0261.12763
- By:
- Publication type:
- Article
Exploiting DNA repair defects in colorectal cancer.
- Published in:
- Molecular Oncology, 2019, v. 13, n. 4, p. 681, doi. 10.1002/1878-0261.12467
- By:
- Publication type:
- Article
Early‐onset colorectal cancer in young individuals.
- Published in:
- Molecular Oncology, 2019, v. 13, n. 2, p. 109, doi. 10.1002/1878-0261.12417
- By:
- Publication type:
- Article
Blood circulating tumor DNA for non-invasive genotyping of colon cancer patients.
- Published in:
- Molecular Oncology, 2016, v. 10, n. 3, p. 475, doi. 10.1016/j.molonc.2015.12.005
- By:
- Publication type:
- Article
Acquired resistance to EGFR-targeted therapies in colorectal cancer.
- Published in:
- Molecular Oncology, 2014, v. 8, n. 6, p. 1084, doi. 10.1016/j.molonc.2014.05.003
- By:
- Publication type:
- Article
HER2 Positivity Predicts Unresponsiveness to EGFR‐Targeted Treatment in Metastatic Colorectal Cancer.
- Published in:
- Oncologist, 2019, v. 24, n. 10, p. 1395, doi. 10.1634/theoncologist.2018-0785
- By:
- Publication type:
- Article
Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient.
- Published in:
- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1130852
- By:
- Publication type:
- Article
Activation of β-Catenin by Oncogenic PIK3CA and EGFR Promotes Resistance to Glucose Deprivation by Inducing a Strong Antioxidant Response.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037526
- By:
- Publication type:
- Article
Active PI3K Pathway Causes an Invasive Phenotype Which Can Be Reversed or Promoted by Blocking the Pathway at Divergent Nodes.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036402
- By:
- Publication type:
- Article
KRAS Mutations Testing in Colorectal Carcinoma Patients in Italy: From Guidelines to External Quality Assessment.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029146
- By:
- Publication type:
- Article