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Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19.
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- British Journal of Clinical Pharmacology, 2014, v. 77, n. 3, p. 554, doi. 10.1111/bcp.12207
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- Article
Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling.
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- Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 5, p. 976, doi. 10.1002/cpt.1955
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- Article
Evaluation of Maternal Drug Exposure Following the Administration of Antenatal Corticosteroids During Late Pregnancy Using Physiologically‐Based Pharmacokinetic Modeling.
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- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 1, p. 164, doi. 10.1002/cpt.1438
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- Article
Modeling Cyclosporine A Inhibition of the Distribution of a P-Glycoprotein PET Ligand, <sup>11</sup>C-Verapamil, into the Maternal Brain and Fetal Liver of the Pregnant Nonhuman Primate: Impact of Tissue Blood Flow and Site of Inhibition.
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- Journal of Nuclear Medicine, 2013, v. 54, n. 3, p. 437, doi. 10.2967/jnumed.112.111732
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- Article
Prediction of CYP‐mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator.
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- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 7, p. 822, doi. 10.1002/psp4.12794
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- Article
Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 2, p. 103, doi. 10.1002/psp4.12274
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- Article
Assessment of the persistence of anacetrapib and evacetrapib concentrations using two pharmacokinetic modeling approaches.
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- Journal of Clinical Pharmacology, 2015, v. 55, n. 7, p. 757, doi. 10.1002/jcph.472
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- Article
Estimation of brain receptor occupancy for trazodone immediate release and once a day formulations.
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- CTS: Clinical & Translational Science, 2022, v. 15, n. 6, p. 1417, doi. 10.1111/cts.13253
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- Article