Found: 16
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Mineralocorticoid receptor (MR) antagonist eplerenone and MR modulator balcinrenone prevent renal extracellular matrix remodeling and inflammation via the MR/proteoglycan/TLR4 pathway.
- Published in:
- Clinical Science, 2024, v. 138, n. 16, p. 1025, doi. 10.1042/CS20240302
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- Article
Structural Aspects of the Gastric H, K ATPase<sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1997, v. 834, n. 1, p. 65, doi. 10.1111/j.1749-6632.1997.tb52226.x
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- Article
Preclinical pharmacology of AZD9977: A novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion.
- Published in:
- PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0193380
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- Article
Bilirubin levels and kidney function decline: An analysis of clinical trial and real world data.
- Published in:
- PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0269970
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- Article
Ageing <i>Fxr</i> Deficient Mice Develop Increased Energy Expenditure, Improved Glucose Control and Liver Damage Resembling NASH
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064721
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- Publication type:
- Article
The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels.
- Published in:
- International Journal of Molecular Medicine, 2016, v. 38, n. 3, p. 961, doi. 10.3892/ijmm.2016.2681
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- Article
Mineralocorticoid Receptor Antagonism Prevents the Synergistic Effect of Metabolic Challenge and Chronic Kidney Disease on Renal Fibrosis and Inflammation in Mice.
- Published in:
- Frontiers in Physiology, 2022, p. 1, doi. 10.3389/fphys.2022.859812
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- Article
Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity.
- Published in:
- ChemMedChem, 2017, v. 12, n. 1, p. 50, doi. 10.1002/cmdc.201600529
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- Article
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
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- EMBO Journal, 2005, v. 24, n. 14, p. 2624, doi. 10.1038/sj.emboj.7600728
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- Article
Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.
- Published in:
- PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171474
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- Article
Effect of AZD9977 and spironolactone on serum potassium in heart failure with preserved or mildly reduced ejection fraction, and renal impairment: A randomized trial.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 10, p. 2493, doi. 10.1111/cts.13377
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- Article
The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone.
- Published in:
- 2019
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- Publication type:
- journal article
Tesaglitazar, a PPAR{alpha}/{gamma} Agonist, Induces Interstitial Mesenchymal Cell DNA Synthesis and Fibrosarcomas in Subcutaneous Tissues in Rats.
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- Toxicological Sciences, 2007, v. 98, n. 1, p. 63, doi. 10.1093/toxsci/kfm094
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- Article
Na restriction activates epithelial Na channels in rat kidney through two mechanisms and decreases distal Na<sup>+</sup> delivery.
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- Journal of Physiology, 2018, v. 596, n. 16, p. 3585, doi. 10.1113/JP275988
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- Publication type:
- Article
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator.
- Published in:
- British Journal of Clinical Pharmacology, 2018, v. 84, n. 7, p. 1486, doi. 10.1111/bcp.13562
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- Publication type:
- Article
Molecular tuning of farnesoid X receptor partial agonism.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10853-2
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- Publication type:
- Article