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Membrane-permeable Triphosphate Prodrugs of Nucleoside Analogues.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 17, p. 5341, doi. 10.1002/ange.201511808
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- Article
Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.
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- Investigational New Drugs, 2011, v. 29, n. 3, p. 456, doi. 10.1007/s10637-009-9377-7
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- Article
Clinical efficacy of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) in the treatment of feline immunodeficiency virus-infected cats.
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- Journal of Feline Medicine & Surgery, 2012, v. 14, n. 2, p. 107, doi. 10.1177/1098612X11431040
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- Article
Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromvinyl)-2'-deoxyuridine (BVDU).
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- Pest Management Science, 2005, v. 61, n. 8, p. 737, doi. 10.1002/ps.1053
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- Article
Synthesis, Antiviral Evaluation, and Computational Studies of Cyclobutane and Cyclobutene L-Nucleoside Analogues.
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- European Journal of Organic Chemistry, 2013, v. 2013, n. 34, p. 7761, doi. 10.1002/ejoc.201301097
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- Article
Diastereoselective Synthesis of (Aryloxy)phosphoramidate Prodrugs.
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- European Journal of Organic Chemistry, 2011, v. 2011, n. 25, p. 4899, doi. 10.1002/ejoc.201100614
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- Article
Synthesis of the 5′-Fluoro-2′β-methyl Analogues of Neplanocin.
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- European Journal of Organic Chemistry, 2011, v. 2011, n. 14, p. 2685, doi. 10.1002/ejoc.201100062
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- Article
Synthesis and Antiviral Evaluation of Carbocyclic 3′-Azidothymidine (AZT) Analogues and Their cycloSal-Phosphate Triesters.
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- European Journal of Organic Chemistry, 2006, v. 2006, n. 4, p. 932, doi. 10.1002/ejoc.200500719
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- Article
Second-Generation cycloSal-d4TMP Pronucleotides Bearing Esterase-Cleavable Sites — The “Trapping” Concept.
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- European Journal of Organic Chemistry, 2006, v. 2006, n. 1, p. 197, doi. 10.1002/ejoc.200500490
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- Article
3,5-Di-(tert-Butyl)-6-fluoro-cycloSal-d4TMP - A Pronucleotide with a Considerably Improved Masking Group.
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- European Journal of Organic Chemistry, 2003, v. 2003, n. 24, p. 4786, doi. 10.1002/ejoc.200300537
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- Article
Bioreversible Protection of Nucleoside Diphosphates.
- Published in:
- Angewandte Chemie International Edition, 2008, v. 47, n. 45, p. 8719, doi. 10.1002/anie.200803100
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- Article
HIV-1 envelope trimer has similar binding characteristics for carbohydrate-binding agents as monomeric gp120
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- FEBS Letters, 2013, v. 587, n. 7, p. 860, doi. 10.1016/j.febslet.2013.02.037
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- Article
Synthesis and Anti- HIV Activity of 4-(Naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl Derivatives.
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- Chemical Biology & Drug Design, 2014, v. 84, n. 4, p. 420, doi. 10.1111/cbdd.12328
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- Article
Design, Synthesis, and Biological Evaluation of Novel 3,5-Disubstituted-1,2,6-Thiadiazine-1,1-Dione Derivatives as HIV-1 NNRTIs.
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- Chemical Biology & Drug Design, 2013, v. 82, n. 4, p. 384, doi. 10.1111/cbdd.12160
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- Article
Cytostatic and Antiviral Activity Evaluations of Hydroxamic Derivatives of Some Non-steroidal Anti-inflammatory Drugs.
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- Chemical Biology & Drug Design, 2009, v. 73, n. 3, p. 328, doi. 10.1111/j.1747-0285.2009.00774.x
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- Article
Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design.
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- BMC Structural Biology, 2006, v. 6, p. 22, doi. 10.1186/1472-6807-6-22
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- Article
Diastereoselective Synthesis of cycloSaligenyl-Nucleosyl-Phosphotriesters.
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- Chemistry - A European Journal, 2011, v. 17, n. 5, p. 1649, doi. 10.1002/chem.201002657
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- Article
Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues.
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- Archiv der Pharmazie, 1997, v. 330, n. 8, p. 265, doi. 10.1002/ardp.19973300807
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- Article
Synthesis of 5′- N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds.
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- Archiv der Pharmazie, 1991, v. 324, n. 8, p. 497, doi. 10.1002/ardp.2503240807
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- Article
The dual role of thymidine phosphorylase in cancer development and chemotherapy.
- Published in:
- Medicinal Research Reviews, 2009, v. 29, n. 6, p. 903, doi. 10.1002/med.20159
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- Article
Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): Present and future.
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- Medicinal Research Reviews, 2008, v. 28, n. 5, p. 797, doi. 10.1002/med.20124
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- Article
The regulation of HIV-1 transcription: Molecular targets for chemotherapeutic intervention.
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- Medicinal Research Reviews, 2006, v. 26, n. 5, p. 595, doi. 10.1002/med.20081
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- Article
Skin Damages—Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System.
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- Molecules, 2020, v. 25, n. 18, p. 4324, doi. 10.3390/molecules25184324
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- Article
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
- Published in:
- Molecules, 2020, v. 25, n. 7, p. 1690, doi. 10.3390/molecules25071690
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- Article
Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones.
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- Molecules, 2016, v. 21, n. 5, p. 579, doi. 10.3390/molecules21050579
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- Article
Evaluation of the Toxicity of 5-Aryl-2-Aminoimidazole-Based Biofilm Inhibitors against Eukaryotic Cell Lines, Bone Cells and the Nematode Caenorhabditis elegans.
- Published in:
- Molecules, 2014, v. 19, n. 10, p. 16707, doi. 10.3390/molecules191016707
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- Article
The Novel [4,5-e][1,3]Diazepine-4,8-dione and Acyclic Carbamoyl Imino-Ureido Derivatives of Imidazole: Synthesis, Anti-Viral and Anti-Tumor Activity Evaluations.
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- Molecules, 2013, v. 18, n. 11, p. 13385, doi. 10.3390/molecules181113385
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- Article
New Sorafenib Derivatives: Synthesis, Antiproliferative Activity Against Tumour Cell Lines and Antimetabolic Evaluation.
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- Molecules, 2012, v. 17, n. 1, p. 1124, doi. 10.3390/molecules17011124
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- Article
Benzylidene-bis-(4-Hydroxycoumarin) and Benzopyrano-Coumarin Derivatives: Synthesis, <sup>1</sup>H/<sup>13</sup>C-NMR Conformational and X-ray Crystal Structure Studies and In Vitro Antiviral Activity Evaluations.
- Published in:
- Molecules, 2011, v. 16, n. 7, p. 6023, doi. 10.3390/molecules16076023
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- Article
Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals.
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- Nature Communications, 2015, v. 6, n. 10, p. 8716, doi. 10.1038/ncomms9716
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- Article
γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV.
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- ChemMedChem, 2021, v. 16, n. 3, p. 499, doi. 10.1002/cmdc.202000712
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- Article
Symmetrical Diamidates as a Class of Phosphate Prodrugs to Deliver the 5′‐Monophosphate Forms of Anticancer Nucleoside Analogues.
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- ChemMedChem, 2018, v. 13, n. 21, p. 2305, doi. 10.1002/cmdc.201800504
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- Article
Enantiocontrolled Preparation of ϒ-Substituted Cyclohexenones: Synthesis and Kinase Activity Assays of Cyclopropyl-Fused Cyclohexane Nucleosides.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9704, doi. 10.3390/ijms23179704
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- Article
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models.
- Published in:
- PLoS Pathogens, 2016, v. 12, n. 9, p. 1, doi. 10.1371/journal.ppat.1005851
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- Article
A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity.
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- PLoS Pathogens, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.ppat.1003456
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- Article
Synthesis of 5-Amino-3,3-dimethyl-7-phenyl-3 H-[1,2]oxathiolo[4,3- b]pyridine-6-carbonitrile 1,1-Dioxides.
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- Journal of Heterocyclic Chemistry, 2014, v. 51, n. 5, p. 1452, doi. 10.1002/jhet.1678
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- Article
Cyclopentene carbocyclic nucleosides related to the antitumor nucleoside clitocine and their conversion to 8-Aza-neplanocin analogues. Synthesis and antiviral activity.
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- Journal of Heterocyclic Chemistry, 1993, v. 30, n. 5, p. 1393, doi. 10.1002/jhet.5570300536
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- Publication type:
- Article
Synthesis of 2-carbamoylmethyl-6-β-D-ribofuranosylpyridine with the aid of a Pd(0)-catalyzed reaction.
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- Journal of Heterocyclic Chemistry, 1993, v. 30, n. 5, p. 1245, doi. 10.1002/jhet.5570300513
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- Publication type:
- Article
3′-(1,2,3-Triazol-1-yl)-2′,3′-dideoxythymidine and 3′-(1,2,3-triazol-1-yl)-2′,3′-dideoxyuridine.
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- Journal of Heterocyclic Chemistry, 1989, v. 26, n. 6, p. 1635, doi. 10.1002/jhet.5570260624
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- Article
Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy.
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- Nature Reviews Microbiology, 2007, v. 5, n. 8, p. 583, doi. 10.1038/nrmicro1707
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- Article
Design, Synthesis, and Biological Evaluation of Novel 2 H-Pyran-2-one Derivatives as Potential HIV-1 Reverse Transcriptase Inhibitors.
- Published in:
- Archiv der Pharmazie, 2015, v. 348, n. 1, p. 23, doi. 10.1002/ardp.201400235
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- Publication type:
- Article
1-Amino-3-(1 H-1,2,3-triazol-1-yl)propylphosphonates as Acyclic Analogs of Nucleotides.
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- Archiv der Pharmazie, 2014, v. 347, n. 7, p. 496, doi. 10.1002/ardp.201300471
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- Publication type:
- Article
Novel Acyclic Phosphonylated 1,2,3-Triazolonucleosides with an Acetamidomethyl Linker: Synthesis and Biological Activity.
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- Archiv der Pharmazie, 2014, v. 347, n. 7, p. 506, doi. 10.1002/ardp.201300468
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- Article
Antiproliferative and Antiviral Activity of Three Libraries of Adamantane Derivatives.
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- Archiv der Pharmazie, 2014, v. 347, n. 5, p. 334, doi. 10.1002/ardp.201300345
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- Article
Design, Synthesis, Antiviral, and Cytostatic Evaluation of Novel Isoxazolidine Analogs of Homonucleotides.
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- Archiv der Pharmazie, 2014, v. 347, n. 5, p. 341, doi. 10.1002/ardp.201300382
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- Article
Synthesis of 1,2,3- Triazolyl Nucleoside Analogs as Potential Anti- Influenza A ( H3 N2 Subtype) Virus Agents.
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- Archiv der Pharmazie, 2014, v. 347, n. 2, p. 134, doi. 10.1002/ardp.201300260
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- Article
Synthesis of a New Series of Phosphonylated 1,2,3- Triazoles as Acyclic Analogs of Ribavirin.
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- Archiv der Pharmazie, 2013, v. 346, n. 9, p. 677, doi. 10.1002/ardp.201300156
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- Article
Synthesis and Biological Evaluation of Novel 1,2,3-Triazolonucleotides.
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- Archiv der Pharmazie, 2013, v. 346, n. 4, p. 278, doi. 10.1002/ardp.201200421
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- Publication type:
- Article
Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues.
- Published in:
- Archiv der Pharmazie, 2005, v. 338, n. 10, p. 457, doi. 10.1002/ardp.200400961
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- Article
Synthesis of 3-Nitrosoimidazo[1,2- a]pyridine Derivatives as Potential Antiretroviral Agents.
- Published in:
- Archiv der Pharmazie, 2001, v. 334, n. 7, p. 224, doi. 10.1002/1521-4184(200107)334:7<224::AID-ARDP224>3.0.CO;2-7
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- Article