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Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson's disease.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04131-9
By:
- Hideshima, Makoto;
- Kimura, Yasuyoshi;
- Aguirre, César;
- Kakuda, Keita;
- Takeuchi, Toshihide;
- Choong, Chi-Jing;
- Doi, Junko;
- Nabekura, Kei;
- Yamaguchi, Keiichi;
- Nakajima, Kichitaro;
- Baba, Kousuke;
- Nagano, Seiichi;
- Goto, Yuji;
- Nagai, Yoshitaka;
- Mochizuki, Hideki;
- Ikenaka, Kensuke
Publication type:
Article
Liver Cancer with Overlapping Myasthenia Gravis, Myocarditis, Seronegative Autoimmune Autonomic Ganglionopathy, and Myositis Symptoms Induced by Atezolizumab.
Published in:
Internal Medicine, 2024, v. 63, n. 15, p. 2193, doi. 10.2169/internalmedicine.1801-23
By:
- Ryoko Shibuya;
- Kousuke Baba;
- Risako Furuta;
- Hiroki Maesaka;
- Hiroaki Hirosawa;
- Tadashi Bando;
- Akira Oshima;
- Hiroshi Onoda;
- Takamasa Nukui;
- Nobuhiro Dougu;
- Shuji Joho;
- Yuji Nakatsuji
Publication type:
Article
Lung Cancer Wherein Durvalumab Induced Both Anti-CRMP-5 Antibody-related Paraneoplastic Neurological Syndromes and Neurological Adverse Events.
Published in:
Internal Medicine, 2024, v. 54, n. 7, p. 1009, doi. 10.2169/internalmedicine.1771-23
By:
- Tomokazu Seki;
- Kousuke Baba;
- Tomohiro Hayashi;
- Risako Furuta;
- Hiroaki Hirosawa;
- Taichi Mitsui;
- Hiroki Maesaka;
- Syuhei Takasawa;
- Toshiro Miwa;
- Keiko Tanaka;
- Yuji Nakatsuji
Publication type:
Article
A Mild Clinical Phenotype with Myopathic and Hemolytic Forms of Phosphoglycerate Kinase Deficiency (PGK Osaka): A Case Report and Literature Review.
Published in:
Internal Medicine, 2022, v. 61, n. 23, p. 3589, doi. 10.2169/internalmedicine.9221-21
By:
- Kousuke Baba;
- Tokiko Fukuda;
- Mitsuru Furuta;
- Satoru Tada;
- Atsuko Imai;
- Yoshihiro Asano;
- Hideo Sugie;
- Takahashi, Masanori P.;
- Hideki Mochizuki
Publication type:
Article
Erdheim-Chester Disease Involving the Central Nervous System with Latent Toxoplasmosis.
Published in:
Internal Medicine, 2022, v. 61, n. 17, p. 2661, doi. 10.2169/internalmedicine.8564-21
By:
- Tomoya Wadayama;
- Mikito Shimizu;
- Ikko Kimura;
- Kousuke Baba;
- Goichi Beck;
- Seiichi Nagano;
- Ryo Morita;
- Hidenori Nakagawa;
- Michinori Shirano;
- Tetsushi Goto;
- Kazumi Norose;
- Kenji Hikosaka;
- Shigeo Murayama;
- Hideki Mochizuki
Publication type:
Article
Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141629
By:
- Beck, Goichi;
- Shinzawa, Koei;
- Hayakawa, Hideki;
- Baba, Kousuke;
- Yasuda, Toru;
- Sumi-Akamaru, Hisae;
- Tsujimoto, Yoshihide;
- Mochizuki, Hideki
Publication type:
Article
Knockdown of the mitochondria-localized protein p13 protects against experimental parkinsonism.
Published in:
EMBO Reports, 2018, v. 19, n. 3, p. 1, doi. 10.15252/embr.201744860
By:
- Naoki Inoue;
- Sae Ogura;
- Atsushi Kasai;
- Takanobu Nakazawa;
- Kazuya Ikeda;
- Shintaro Higashi;
- Ayako Isotani;
- Kousuke Baba;
- Hideki Mochizuki;
- Harutoshi Fujimura;
- Yukio Ago;
- Atsuko Hayata-Takano;
- Kaoru Seiriki;
- Yusuke Shintani;
- Norihito Shintani;
- Hitoshi Hashimoto
Publication type:
Article
Elevated Serum Xanthine Oxidase and Its Correlation with Antioxidant Status in Patients with Parkinson's Disease.
Published in:
Biomolecules (2218-273X), 2024, v. 14, n. 4, p. 490, doi. 10.3390/biom14040490
By:
- Haryuni, Ratna Dini;
- Nukui, Takamasa;
- Piao, Jin-Lan;
- Shirakura, Takashi;
- Matsui, Chieko;
- Sugimoto, Tomoyuki;
- Baba, Kousuke;
- Nakane, Shunya;
- Nakatsuji, Yuji
Publication type:
Article
Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43772-9
By:
- Uehara, Takuya;
- Choong, Chi-Jing;
- Nakamori, Masayuki;
- Hayakawa, Hideki;
- Nishiyama, Kumiko;
- Kasahara, Yuuya;
- Baba, Kousuke;
- Nagata, Tetsuya;
- Yokota, Takanori;
- Tsuda, Hiroshi;
- Obika, Satoshi;
- Mochizuki, Hideki
Publication type:
Article
Long‐Term Implantable, Flexible, and Transparent Neural Interface Based on Ag/Au Core–Shell Nanowires.
Published in:
Advanced Healthcare Materials, 2019, v. 8, n. 10, p. N.PAG, doi. 10.1002/adhm.201900130
By:
- Araki, Teppei;
- Yoshida, Fumiaki;
- Uemura, Takafumi;
- Noda, Yuki;
- Yoshimoto, Shusuke;
- Kaiju, Taro;
- Suzuki, Takafumi;
- Hamanaka, Hiroki;
- Baba, Kousuke;
- Hayakawa, Hideki;
- Yabumoto, Taiki;
- Mochizuki, Hideki;
- Kobayashi, Shingo;
- Tanaka, Masaru;
- Hirata, Masayuki;
- Sekitani, Tsuyoshi
Publication type:
Article
Go-sha-jinki-Gan (GJG) ameliorates allodynia in chronic constriction injury model mice via suppression of TNF-α expression in the spinal cord.
Published in:
Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916656382
By:
- Nakanishi, Miho;
- Nakae, Aya;
- Kishida, Yuki;
- Baba, Kousuke;
- Sakashita, Noriko;
- Shibata, Masahiko;
- Yoshikawa, Hideki;
- Hagihara, Keisuke
Publication type:
Article
Go-sha-jinki-Gan (GJG) ameliorates allodynia in chronic constriction injury model mice via suppression of TNF-α expression in the spinal cord.
Published in:
Molecular Pain, 2016, v. 12, p. 1, doi. 10.1177/1744806916656382
By:
- Miho Nakanishi;
- Aya Nakae;
- Yuki Kishida;
- Kousuke Baba;
- Noriko Sakashita;
- Masahiko Shibata;
- Hideki Yoshikawa;
- Keisuke Hagihara
Publication type:
Article
In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
Published in:
Human Molecular Genetics, 2018, v. 27, n. 22, p. 3974, doi. 10.1093/hmg/ddy279
By:
- Uenaka, Takeshi;
- Satake, Wataru;
- Cha, Pei-Chieng;
- Hayakawa, Hideki;
- Baba, Kousuke;
- Jiang, Shiying;
- Kobayashi, Kazuhiro;
- Kanagawa, Motoi;
- Okada, Yukinori;
- Mochizuki, Hideki
Publication type:
Article
Serum asymmetric dimethylarginine level correlates with the progression and prognosis of amyotrophic lateral sclerosis.
Published in:
European Journal of Neurology, 2022, v. 29, n. 5, p. 1410, doi. 10.1111/ene.15254
By:
- Ikenaka, Kensuke;
- Maeda, Yasuhiro;
- Hotta, Yuji;
- Nagano, Seiichi;
- Yamada, Shinichiro;
- Ito, Daisuke;
- Torii, Ryota;
- Kakuda, Keita;
- Tatebe, Harutsugu;
- Atsuta, Naoki;
- Aguirre, Cesar;
- Kimura, Yasuyoshi;
- Baba, Kousuke;
- Tokuda, Takahiko;
- Katsuno, Masahisa;
- Kimura, Kazunori;
- Sobue, Gen;
- Mochizuki, Hideki
Publication type:
Article
Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A<sub>2</sub>β Knockout Mice.
Published in:
PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153789
By:
- Beck, Goichi;
- Shinzawa, Koei;
- Hayakawa, Hideki;
- Baba, Kousuke;
- Sumi-Akamaru, Hisae;
- Tsujimoto, Yoshihide;
- Mochizuki, Hideki
Publication type:
Article
Structurally distinct α-synuclein fibrils induce robust parkinsonian pathology.
Published in:
2020
By:
- Hayakawa, Hideki;
- Nakatani, Rie;
- Ikenaka, Kensuke;
- Aguirre, Cesar;
- Choong, Chi‐Jing;
- Tsuda, Hiroshi;
- Nagano, Seiichi;
- Koike, Masato;
- Ikeuchi, Takeshi;
- Hasegawa, Masato;
- Papa, Stella M.;
- Nagai, Yoshitaka;
- Mochizuki, Hideki;
- Baba, Kousuke;
- Choong, Chi-Jing
Publication type:
journal article
Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.
Published in:
Acta Neuropathologica, 2023, v. 145, n. 5, p. 573, doi. 10.1007/s00401-023-02555-3
By:
- Choong, Chi-Jing;
- Aguirre, César;
- Kakuda, Keita;
- Beck, Goichi;
- Nakanishi, Hiroki;
- Kimura, Yasuyoshi;
- Shimma, Shuichi;
- Nabekura, Kei;
- Hideshima, Makoto;
- Doi, Junko;
- Yamaguchi, Keiichi;
- Nakajima, Kichitaro;
- Wadayama, Tomoya;
- Hayakawa, Hideki;
- Baba, Kousuke;
- Ogawa, Kotaro;
- Takeuchi, Toshihide;
- Badawy, Shaymaa Mohamed Mohamed;
- Murayama, Shigeo;
- Nagano, Seiichi
Publication type:
Article
Increased Expression of Fibronectin Leucine-Rich Transmembrane Protein 3 in the Dorsal Root Ganglion Induces Neuropathic Pain in Rats.
Published in:
Journal of Neuroscience, 2019, v. 39, n. 38, p. 7615, doi. 10.1523/jneurosci.0295-19.2019
By:
- Moe Yamada;
- Yuki Fujita;
- Yasufumi Hayano;
- Hideki Hayakawa;
- Kousuke Baba;
- Hideki Mochizuki;
- Toshihide Yamashita
Publication type:
Article
Ultrasonication-based rapid amplification of α-synuclein aggregates in cerebrospinal fluid.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-42399-0
By:
- Kakuda, Keita;
- Ikenaka, Kensuke;
- Araki, Katsuya;
- So, Masatomo;
- Aguirre, César;
- Kajiyama, Yuta;
- Konaka, Kuni;
- Noi, Kentaro;
- Baba, Kousuke;
- Tsuda, Hiroshi;
- Nagano, Seiichi;
- Ohmichi, Takuma;
- Nagai, Yoshitaka;
- Tokuda, Takahiko;
- El-Agnaf, Omar M. A.;
- Ogi, Hirotsugu;
- Goto, Yuji;
- Mochizuki, Hideki
Publication type:
Article
Alpha‐synuclein dynamics in induced pluripotent stem cell‐derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
Published in:
FEBS Open Bio, 2021, v. 11, n. 2, p. 354, doi. 10.1002/2211-5463.13060
By:
- Fukusumi, Hayato;
- Togo, Kazuyuki;
- Sumida, Miho;
- Nakamori, Masayuki;
- Obika, Satoshi;
- Baba, Kousuke;
- Shofuda, Tomoko;
- Ito, Daisuke;
- Okano, Hideyuki;
- Mochizuki, Hideki;
- Kanemura, Yonehiro
Publication type:
Article
E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease.
Published in:
PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218261
By:
- Sakai, Ryusuke;
- Suzuki, Mari;
- Ueyama, Morio;
- Takeuchi, Toshihide;
- Minakawa, Eiko N.;
- Hayakawa, Hideki;
- Baba, Kousuke;
- Mochizuki, Hideki;
- Nagai, Yoshitaka
Publication type:
Article
Parkinson's disease and iron.
Published in:
Journal of Neural Transmission, 2020, v. 127, n. 2, p. 181, doi. 10.1007/s00702-020-02149-3
By:
- Mochizuki, Hideki;
- Choong, Chi-Jing;
- Baba, Kousuke
Publication type:
Article
piRNA/PIWI Protein Complex as a Potential Biomarker in Sporadic Amyotrophic Lateral Sclerosis.
Published in:
Molecular Neurobiology, 2022, v. 59, n. 3, p. 1693, doi. 10.1007/s12035-021-02686-2
By:
- Abdelhamid, Rehab F.;
- Ogawa, Kotaro;
- Beck, Goichi;
- Ikenaka, Kensuke;
- Takeuchi, Eriko;
- Yasumizu, Yoshiaki;
- Jinno, Jyunki;
- Kimura, Yasuyoshi;
- Baba, Kousuke;
- Nagai, Yoshitaka;
- Okada, Yukinori;
- Saito, Yuko;
- Murayama, Shigeo;
- Mochizuki, Hideki;
- Nagano, Seiichi
Publication type:
Article
Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro.
Published in:
Molecular Brain, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13041-021-00851-1
By:
- Togo, Kazuyuki;
- Fukusumi, Hayato;
- Shofuda, Tomoko;
- Ohnishi, Hiroshi;
- Yamazaki, Hiroyuki;
- Hayashi, Mariko Kato;
- Kawasaki, Nana;
- Takei, Nobuyuki;
- Nakazawa, Takanobu;
- Saito, Yumiko;
- Baba, Kousuke;
- Hashimoto, Hitoshi;
- Sekino, Yuko;
- Shirao, Tomoaki;
- Mochizuki, Hideki;
- Kanemura, Yonehiro
Publication type:
Article
Quantitative behavioral evaluation of a non-human primate stroke model using a new monitoring system.
Published in:
Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.964928
By:
- Toshikazu Hirohata;
- Takaya Kitano;
- Chizu Saeki;
- Kousuke Baba;
- Fumiaki Yoshida;
- Takashi Kurihara;
- Katsuhiro Harada;
- Shigeyoshi Saito;
- Hideki Mochizuki;
- Megumi Shimodozono
Publication type:
Article

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