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Innovating Therapies for Down Syndrome: An International Virtual Conference of the T21 Research Society.
- Published in:
- Molecular Syndromology, 2023, v. 14, n. 2, p. 89, doi. 10.1159/000526021
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- Article
Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society.
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- Molecular Syndromology, 2021, v. 12, n. 4, p. 202, doi. 10.1159/000514437
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- Article
Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society.
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- Molecular Syndromology, 2018, v. 9, n. 6, p. 279, doi. 10.1159/000494231
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- Article
Evolution of neuroinflammation across the lifespan of individuals with Down syndrome.
- Published in:
- 2020
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- Publication type:
- journal article
Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport.
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- Journal of Neuroscience, 2003, v. 23, n. 11, p. 4499, doi. 10.1523/JNEUROSCI.23-11-04499.2003
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- Publication type:
- Article
Aberrant Activation of Focal Adhesion Proteins Mediates Fibrillar Amyloid Β-Induced Neuronal Dystrophy.
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- Journal of Neuroscience, 2003, v. 23, n. 2, p. 493, doi. 10.1523/JNEUROSCI.23-02-00493.2003
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- Publication type:
- Article
Changes of basal forebrain volume along the Alzheimer's disease continuum in Down syndrome.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067239
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- Article
Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26270-3
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- Article
Low Cost Electrode Assembly for EEG Recordings in Mice.
- Published in:
- Frontiers in Neuroscience, 2017, p. 1, doi. 10.3389/fnins.2017.0062
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- Publication type:
- Article
EARLY AND LATE NEUROINFLAMMATORY EVENTS AS ALZHEIMER’S DISEASE PATHOLOGY EVOLVES IN DOWN SYNDROME INDIVIDUALS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P984, doi. 10.1016/j.jalz.2017.06.1340
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- Article
Altered zinc neuromodulation induces neuronal hyperactivity and cognitive impairment.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P634, doi. 10.1016/j.jalz.2015.06.908
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- Article
Investigating the role of synaptic zinc and seizure activity in Alzheimer's disease
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- 2012
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- Abstract
Spine pathology in down's syndrome and Alzheimer's disease
- Published in:
- 2011
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- Abstract
P4-183: Increased oxidative stress is an early pathological feature in 3xTg-AD mice
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- 2008
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- Abstract
O2-02-07: Neuronal activity promotes oligomer formation and accumulation at excitatory synapses
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- 2008
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- Abstract
P4-014: Divergent cytotoxic mechanisms of soluble and fibrillar forms of AAY in human cortical neurons
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- 2006
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- Abstract
O4-02-07: Mitochondrial dysfunction and Alzheimer’s disease in Down’s Syndrome
- Published in:
- 2006
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- Publication type:
- Abstract
P4-014: Divergent cytotoxic mechanisms of soluble and fibrillar forms of AAY in human cortical neurons
- Published in:
- 2006
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- Publication type:
- Abstract
O4-02-07: Mitochondrial dysfunction and Alzheimer’s disease in Down’s Syndrome
- Published in:
- 2006
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- Publication type:
- Abstract
A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome.
- Published in:
- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014200
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- Article
Stress, Aging, and Neurodegenerative Disorders: Molecular Mechanisms<sup>a</sup>.
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- Annals of the New York Academy of Sciences, 1998, v. 851, n. 1, p. 429, doi. 10.1111/j.1749-6632.1998.tb09021.x
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- Article
Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia.
- Published in:
- 2012
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- Publication type:
- Journal Article
Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia.
- Published in:
- Current Gerontology & Geratrics Research, 2012, p. 1, doi. 10.1155/2012/383170
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- Publication type:
- Article
A Role for Synaptic Zinc in Activity-Dependent Aβ Oligomer Formation and Accumulation at Excitatory Synapses.
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- Journal of Neuroscience, 2009, v. 29, n. 13, p. 4004, doi. 10.1523/JNEUROSCI.5980-08.2009
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- Publication type:
- Article
Phosphorylation of Actin-Depolymerizing Factor/Cofilin by LIM-Kinase Mediates Amyloid β-Induced Degeneration: A Potential Mechanism of Neuronal Dystrophy in Alzheimer's Disease.
- Published in:
- 2006
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- Publication type:
- Abstract
Different Conformations of Amyloid β Induce Neurotoxicity by Distinct Mechanisms in Human Cortical Neurons.
- Published in:
- Journal of Neuroscience, 2006, v. 26, n. 22, p. 6011, doi. 10.1523/JNEUROSCI.1189-06.2006
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- Publication type:
- Article
ets-2 Promotes the Activation of a Mitochondrial Death Pathway in Down's Syndrome Neurons.
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- Journal of Neuroscience, 2005, v. 25, n. 9, p. 2295, doi. 10.1523/JNEUROSCI.5107-04.2005
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- Publication type:
- Article
GVS-111 prevents oxidative damage and apoptosis in normal and Down’s syndrome human cortical neurons
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- International Journal of Developmental Neuroscience, 2003, v. 21, n. 3, p. 117, doi. 10.1016/S0736-5748(03)00031-5
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- Publication type:
- Article
Fast axonal transport misregulation and Alzheimer’s Disease.
- Published in:
- NeuroMolecular Medicine, 2002, v. 2, n. 2, p. 89, doi. 10.1385/NMM:2:2:089
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- Publication type:
- Article
Nerve growth factor metabolic dysfunction in Down's syndrome brains.
- Published in:
- 2014
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- Publication type:
- journal article
Nerve growth factor metabolic dysfunction in Down’s syndrome brains.
- Published in:
- Brain: A Journal of Neurology, 2014, v. 137, n. 3, p. 860, doi. 10.1093/brain/awt372
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- Publication type:
- Article
Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome.
- Published in:
- FASEB Journal, 2014, v. 28, n. 1, p. 195, doi. 10.1096/fj.13-232686
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- Publication type:
- Article
Genetic removal of synaptic Zn<sup>2+</sup> impairs cognition, alters neurotrophic signaling and induces neuronal hyperactivity.
- Published in:
- Frontiers in Neurology, 2023, v. 14, p. 1, doi. 10.3389/fneur.2022.882635
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- Publication type:
- Article
Tau isoform expression and regulation in human cortical neurons.
- Published in:
- FASEB Journal, 2008, v. 22, n. 7, p. 2357, doi. 10.1096/fj.07-096909
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- Publication type:
- Article
Inhibition of β-Amyloid Production by Activation of Protein Kinase C.
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- Journal of Neurochemistry, 1993, v. 61, n. 6, p. 2326, doi. 10.1111/j.1471-4159.1993.tb07479.x
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- Publication type:
- Article
β-Amyloid Neurotoxicity in Human Cortical Culture Is Not Mediated by Excitotoxins.
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- Journal of Neurochemistry, 1993, v. 61, n. 4, p. 1565, doi. 10.1111/j.1471-4159.1993.tb13658.x
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- Article
Apoptosis and increased generation of reactive oxygen...
- Published in:
- Nature, 1995, v. 378, n. 6559, p. 776, doi. 10.1038/378776a0
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- Article
Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells.
- Published in:
- Aging Cell, 2018, v. 17, n. 5, p. 1, doi. 10.1111/acel.12812
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- Publication type:
- Article
Mitochondrial dysfunction and Down's syndrome: Is there a role for coenzyme Q<sub>10</sub>?
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- Biofactors, 2011, v. 37, n. 5, p. 386, doi. 10.1002/biof.184
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- Publication type:
- Article
Changing Paradigms in Down Syndrome: The First International Conference of the Trisomy 21 Research Society.
- Published in:
- Molecular Syndromology, 2016, v. 7, n. 5, p. 251, doi. 10.1159/000449049
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- Publication type:
- Article
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.
- Published in:
- PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006033
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- Article