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Pharmacological sequestration of mitochondrial calcium uptake protects against dementia and β-amyloid neurotoxicity.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16817-9
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- Publication type:
- Article
Infectious Burden and Alzheimer Disease: Is There a Link?
- Published in:
- Psychiatric Times, 2019, v. 36, n. 11, p. 30
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- Publication type:
- Article
A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice.
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- CNS Neuroscience & Therapeutics, 2021, v. 27, n. 7, p. 765, doi. 10.1111/cns.13637
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- Publication type:
- Article
Fluorinated gamma‐carboline derivatives delay motor deficits in transgenic mouse model of neuronal proteinopathy: Nonhuman/Target identification and validation studies: Other.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043282
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- Publication type:
- Article
Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2285, doi. 10.3390/ijms24032285
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- Publication type:
- Article
Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13925, doi. 10.3390/ijms232213925
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- Publication type:
- Article
Bis(Benzofuran–1,3- N , N -heterocycle)s as Symmetric and Synthetic Drug Leads against Yellow Fever Virus.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12675, doi. 10.3390/ijms232012675
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- Publication type:
- Article
α-synuclein mRNA is up-regulated in the striatum of rats following alcohol-intoxication during adolescence.
- Published in:
- Klinik Psikofarmakoloji Bulteni, 2015, v. 25, p. S109
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- Publication type:
- Article
Dimebon Slows Progression of Proteinopathy in γ-Synuclein Transgenic Mice.
- Published in:
- Neurotoxicity Research, 2012, v. 22, n. 1, p. 33, doi. 10.1007/s12640-011-9299-y
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- Publication type:
- Article
P4-337: Dimebon improves cognition, function, and behavior in mild and moderate Alzheimer's disease: Results by severity of a one-year, double-blind, placebo-controlled study
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- 2008
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- Publication type:
- Abstract
S3-02-03: Results of a one-year randomized, placebo-controlled trial of dimebon for the treatment of mild to moderate Alzheimer’s disease
- Published in:
- 2007
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- Publication type:
- Abstract
P1-440: Comparative study of Aricept, Memantine and Dimebon effect on memory and cognition in neurotoxin-induced animal model of Alzheimer’s disease
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- 2006
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- Publication type:
- Abstract
P1-440: Comparative study of Aricept, Memantine and Dimebon effect on memory and cognition in neurotoxin-induced animal model of Alzheimer’s disease
- Published in:
- 2006
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- Publication type:
- Abstract
Quinone reductase 2 and antidepressant effect of melatonin derivatives.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1199, n. 1, p. 121, doi. 10.1111/j.1749-6632.2009.05354.x
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- Publication type:
- Article
Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities.
- Published in:
- Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-05832-w
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- Publication type:
- Article
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment.
- Published in:
- Scientific Reports, 2017, p. 45627, doi. 10.1038/srep45627
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- Publication type:
- Article
Dimebon Does Not Ameliorate Pathological Changes Caused by Expression of Truncated (1-120) Human Alpha-Synuclein in Dopaminergic Neurons of Transgenic Mice.
- Published in:
- Neurodegenerative Diseases, 2011, v. 8, n. 6, p. 430, doi. 10.1159/000324989
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- Publication type:
- Article
Mitochondria as a Target for Neurotoxins and Neuroprotective Agents.
- Published in:
- Annals of the New York Academy of Sciences, 2003, v. 993, n. 1, p. 334, doi. 10.1111/j.1749-6632.2003.tb07541.x
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- Publication type:
- Article
Neuroprotective and Cognition-Enhancing Properties of MK-801 Flexible Analogs.
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- Annals of the New York Academy of Sciences, 2001, v. 939, n. 1, p. 219, doi. 10.1111/j.1749-6632.2001.tb03629.x
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- Publication type:
- Article
Alterations of Astrocytes in the Context of Schizophrenic Dementia.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2019.01612
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- Publication type:
- Article
Differential involvement of the gamma-synuclein in cognitive abilities on the model of knockout mice.
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- BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-53
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- Publication type:
- Article
Differential involvement of the gamma-synuclein in cognitive abilities on the model of knockout mice.
- Published in:
- 2013
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- Publication type:
- journal article
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
- Published in:
- Molecules, 2024, v. 29, n. 2, p. 321, doi. 10.3390/molecules29020321
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- Publication type:
- Article
New Adamantane-Containing Edaravone Conjugates as Potential Neuroprotective Agents for ALS Treatments.
- Published in:
- Molecules, 2023, v. 28, n. 22, p. 7567, doi. 10.3390/molecules28227567
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- Publication type:
- Article
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
- Published in:
- Molecules, 2022, v. 27, n. 3, p. 1060, doi. 10.3390/molecules27031060
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- Publication type:
- Article
Publisher Correction: Synthesis of Saccharumoside-B analogue with potential of antiproliferative and pro-apoptotic activities.
- Published in:
- 2020
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- Publication type:
- Correction Notice
In a search for efficient treatment for amyotrophic lateral sclerosis: Old drugs for new approaches.
- Published in:
- Medicinal Research Reviews, 2021, v. 41, n. 5, p. 2804, doi. 10.1002/med.21725
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- Publication type:
- Article
Neurodegenerative disorders—Searching for targets and new ways of diseases treatment.
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- Medicinal Research Reviews, 2021, v. 41, n. 5, p. 2603, doi. 10.1002/med.21794
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- Publication type:
- Article
Mitochondria as a promising target for developing novel agents for treating Alzheimer's disease.
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- Medicinal Research Reviews, 2021, v. 41, n. 2, p. 803, doi. 10.1002/med.21715
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- Publication type:
- Article
Drugs in Clinical Trials for Alzheimer's Disease: The Major Trends.
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- Medicinal Research Reviews, 2017, v. 37, n. 5, p. 1186, doi. 10.1002/med.21434
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- Publication type:
- Article
Low Level of Expression of C-Terminally Truncated Human FUS Causes Extensive Changes in the Spinal Cord Transcriptome of Asymptomatic Transgenic Mice.
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- Neurochemical Research, 2020, v. 45, n. 5, p. 1168, doi. 10.1007/s11064-020-02999-z
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- Publication type:
- Article
Implication of the Nutritional and Nonnutritional Factors in the Context of Preservation of Cognitive Performance in Patients With Dementia/Depression and Alzheimer Disease.
- Published in:
- 2013
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- Publication type:
- Journal Article
Bis-γ-carbolines as new potential multitarget agents for Alzheimer's disease.
- Published in:
- Pure & Applied Chemistry, 2020, v. 92, n. 7, p. 1057, doi. 10.1515/pac-2019-1206
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- Publication type:
- Article
Focused design of polypharmacophoric neuroprotective compounds: Conjugates of γ-carbolines with carbazole derivatives and tetrahydrocarbazole.
- Published in:
- Pure & Applied Chemistry, 2017, v. 89, n. 8, p. 1167, doi. 10.1515/pac-2017-0308
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- Publication type:
- Article
Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease.
- Published in:
- Scientific Reports, 2015, p. 13164, doi. 10.1038/srep13164
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- Publication type:
- Article
Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease.
- Published in:
- Frontiers in Pharmacology, 2023, p. 01, doi. 10.3389/fphar.2023.1219980
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- Publication type:
- Article
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models
- Published in:
- FEBS Letters, 2009, v. 583, n. 14, p. 2419, doi. 10.1016/j.febslet.2009.06.042
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- Publication type:
- Article
Oxidation Products Arising from the Action of Monoamine Oxidase B on 1-Methyl-4-Benzyl-1,2,3,6-Tetrahydropyridine, a Nonneurotoxic Analogue of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine.
- Published in:
- Journal of Neurochemistry, 1994, v. 62, n. 5, p. 2012, doi. 10.1046/j.1471-4159.1994.62052012.x
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- Publication type:
- Article
Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands.
- Published in:
- Molecules, 2021, v. 26, n. 18, p. 5527, doi. 10.3390/molecules26185527
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- Publication type:
- Article
New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
- Published in:
- Molecules, 2020, v. 25, n. 17, p. 3915, doi. 10.3390/molecules25173915
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- Publication type:
- Article
Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41272-4
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- Publication type:
- Article
Mitochondria and Oxidative Stress as a Link between Alzheimer's Disease and Diabetes Mellitus.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14450, doi. 10.3390/ijms241914450
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- Publication type:
- Article
The Effect of Short-Term Physical Activity on the Oxidative Stress in Rats with Different Stress Resistance Profiles in Cerebral Hypoperfusion.
- Published in:
- Molecular Neurobiology, 2020, v. 57, n. 7, p. 3014, doi. 10.1007/s12035-020-01930-5
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- Publication type:
- Article
Novel Positive Allosteric Modulators of AMPA Receptors Based on 3,7-Diazabicyclo[3.3.1]nonane Scaffold.
- Published in:
- Molecular Neurobiology, 2020, v. 57, n. 1, p. 191, doi. 10.1007/s12035-019-01768-6
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- Publication type:
- Article
The Possibility of an Infectious Etiology of Alzheimer Disease.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 6, p. 4479, doi. 10.1007/s12035-018-1388-y
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- Publication type:
- Article
Pharmacological Sequestration of Mitochondrial Calcium Uptake Protects Neurons Against Glutamate Excitotoxicity.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 3, p. 2244, doi. 10.1007/s12035-018-1204-8
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- Publication type:
- Article
Pro-neurogenic, Memory-Enhancing and Anti-stress Effects of DF302, a Novel Fluorine Gamma-Carboline Derivative with Multi-target Mechanism of Action.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 1, p. 335, doi. 10.1007/s12035-017-0745-6
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- Publication type:
- Article
Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine).
- Published in:
- Molecular Neurobiology, 2015, v. 52, n. 2, p. 970, doi. 10.1007/s12035-015-9249-4
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- Publication type:
- Article
Hippocampal Gene Expression of Deiodinases 2 and 3 and Effects of 3,5-Diiodo-L-Thyronine T2 in Mouse Depression Paradigms.
- Published in:
- BioMed Research International, 2013, v. 2013, p. 1, doi. 10.1155/2013/565218
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- Publication type:
- Article
Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test.
- Published in:
- Neural Plasticity, 2016, p. 1, doi. 10.1155/2016/5098591
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- Publication type:
- Article