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The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02584-6
By:
- Jermakowicz, Anna M.;
- Rybin, Matthew J.;
- Suter, Robert K.;
- Sarkaria, Jann N.;
- Zeier, Zane;
- Feng, Yangbo;
- Ayad, Nagi G.
Publication type:
Article
Multiprotein GLI Transcriptional Complexes as Therapeutic Targets in Cancer.
Published in:
Life (2075-1729), 2022, v. 12, n. 12, p. 1967, doi. 10.3390/life12121967
By:
- Yang, Fan;
- Wynn, Daniel T.;
- Shen, Chen;
- Ayad, Nagi G.;
- Robbins, David J.
Publication type:
Article
The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25634-z
By:
- Shen, Chen;
- Nayak, Anmada;
- Neitzel, Leif R.;
- Adams, Amber A.;
- Silver-Isenstadt, Maya;
- Sawyer, Leah M.;
- Benchabane, Hassina;
- Wang, Huilan;
- Bunnag, Nawat;
- Li, Bin;
- Wynn, Daniel T.;
- Yang, Fan;
- Garcia-Contreras, Marta;
- Williams, Charles H.;
- Dakshanamurthy, Sivanesan;
- Hong, Charles C.;
- Ayad, Nagi G.;
- Capobianco, Anthony J.;
- Ahmed, Yashi;
- Lee, Ethan
Publication type:
Article
Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner.
Published in:
2019
By:
- Winterbottom, Emily F.;
- Moroishi, Yuka;
- Halchenko, Yuliya;
- Armstrong, David A.;
- Beach, Paul J.;
- Nguyen, Quang P.;
- Capobianco, Anthony J.;
- Ayad, Nagi G.;
- Marsit, Carmen J.;
- Li, Zhigang;
- Karagas, Margaret R.;
- Robbins, David J.
Publication type:
journal article
Identifying Glioblastoma Gene Networks Based on Hypergeometric Test Analysis.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0115842
By:
- Stathias, Vasileios;
- Pastori, Chiara;
- Griffin, Tess Z.;
- Komotar, Ricardo;
- Clarke, Jennifer;
- Zhang, Ming;
- Ayad, Nagi G.
Publication type:
Article
Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme.
Published in:
Molecular Cancer, 2018, v. 17, p. 1, doi. 10.1186/s12943-018-0822-0
By:
- Tan, Sze Kiat;
- Pastori, Chiara;
- Penas, Clara;
- Komotar, Ricardo J.;
- Ivan, Michael E.;
- Wahlestedt, Claes;
- Ayad, Nagi G.
Publication type:
Article
Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
Published in:
EMBO Reports, 2023, v. 24, n. 10, p. 1, doi. 10.15252/embr.202357032
By:
- Yang, Hui;
- Sui, Pinpin;
- Guo, Ying;
- Chen, Shi;
- Maloof, Marie E;
- Ge, Guo;
- Nihozeko, Francine;
- Delma, Caroline R;
- Zhu, Ganqian;
- Zhang, Peng;
- Ye, Zhenqing;
- Medina, Edward A;
- Ayad, Nagi G;
- Mesa, Ruben;
- Nimer, Stephen D;
- Chiang, Cheng‐Ming;
- Xu, Mingjiang;
- Chen, Yidong;
- Yang, Feng‐Chun
Publication type:
Article
392 Targeting One-Carbon Metabolism in Brain Cancer.
Published in:
2024
By:
- Rowland, Emma;
- Ayad, Nagi G.
Publication type:
Abstract
Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10799-5
By:
- Penas, Clara;
- Maloof, Marie E.;
- Stathias, Vasileios;
- Long, Jun;
- Tan, Sze Kiat;
- Mier, Jose;
- Fang, Yin;
- Valdes, Camilo;
- Rodriguez-Blanco, Jezabel;
- Chiang, Cheng-Ming;
- Robbins, David J.;
- Liebl, Daniel J.;
- Lee, Jae K.;
- Hatten, Mary E.;
- Clarke, Jennifer;
- Ayad, Nagi G.
Publication type:
Article
Drug and disease signature integration identifies synergistic combinations in glioblastoma.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07659-z
By:
- Stathias, Vasileios;
- Jermakowicz, Anna M.;
- Maloof, Marie E.;
- Forlin, Michele;
- Walters, Winston;
- Suter, Robert K.;
- Durante, Michael A.;
- Williams, Sion L.;
- Harbour, J. William;
- Volmar, Claude-Henry;
- Lyons, Nicholas J.;
- Wahlestedt, Claes;
- Graham, Regina M.;
- Ivan, Michael E.;
- Komotar, Ricardo J.;
- Sarkaria, Jann N.;
- Subramanian, Aravind;
- Golub, Todd R.;
- Schürer, Stephan C.;
- Ayad, Nagi G.
Publication type:
Article
The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex.
Published in:
Nature Cell Biology, 2004, v. 6, n. 2, p. 129, doi. 10.1038/ncb1091
By:
- Min Sup Song, Benjamin J.;
- Su Jeong Song, Benjamin J.;
- Nagi G. Ayad, Benjamin J.;
- Jin Sook Chang, Benjamin J.;
- Joo Hyun Lee, Benjamin J.;
- Hyun Kyung Hong, Benjamin J.;
- Ho Lee;
- Naeyun Choi, Benjamin J.;
- Jhingook Kim;
- Jin Woo Kim;
- Eui-Ju Choi;
- Dae-Sik Lim;
- Hojoong Kim;
- Kirschner, Marc W.
Publication type:
Article
Epigenetic Pathways and Glioblastoma Treatment: Insights From Signaling Cascades.
Published in:
Journal of Cellular Biochemistry, 2015, v. 116, n. 3, p. 351, doi. 10.1002/jcb.24990
By:
- Allen, Bryce K.;
- Stathias, Vasileios;
- Maloof, Marie E.;
- Vidovic, Dusica;
- Winterbottom, Emily F.;
- Capobianco, Anthony J.;
- Clarke, Jennifer;
- Schurer, Stephan;
- Robbins, David J.;
- Ayad, Nagi G.
Publication type:
Article
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.
Published in:
Nature, 2004, v. 428, n. 6979, p. 194, doi. 10.1038/nature02381
By:
- Wenyi Wei;
- Ayad, Nagi G.;
- Yong Wan;
- Guo-Jun Zhang;
- Kirschner, Marc W.;
- Kaelin Jr., William G.
Publication type:
Article
A multiparametric pharmacogenomic strategy for drug repositioning predicts therapeutic efficacy for glioblastoma cell lines.
Published in:
Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdab192
By:
- Shah, Ashish H.;
- Suter, Robert;
- Gudoor, Pavan;
- Doucet-O'Hare, Tara T.;
- Stathias, Vasileios;
- Cajigas, Iahn;
- de la Fuente, Macarena;
- Govindarajan, Vaidya;
- Morell, Alexis A.;
- Eichberg, Daniel G.;
- Luther, Evan;
- Lu, Victor M.;
- Heiss, John;
- Komotar, Ricardo J.;
- Ivan, Michael E.;
- Schurer, Stephan;
- Gilbert, Mark R.;
- Ayad, Nagi G.
Publication type:
Article
Immunotherapy and Epigenetic Pathway Modulation in Glioblastoma Multiforme.
Published in:
Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00521
By:
- Chin, Christopher;
- Lunking, Emma S.;
- de la Fuente, Macarena;
- Ayad, Nagi G.
Publication type:
Article
Organoid Models of Glioblastoma and Their Role in Drug Discovery.
Published in:
Frontiers in Cellular Neuroscience, 2021, v. 15, p. N.PAG, doi. 10.3389/fncel.2021.605255
By:
- Rybin, Matthew J.;
- Ivan, Michael E.;
- Ayad, Nagi G.;
- Zeier, Zane
Publication type:
Article
Neuroinflammation Treatment via Targeted Delivery of Nanoparticles.
Published in:
Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.576037
By:
- Cerqueira, Susana R.;
- Ayad, Nagi G.;
- Lee, Jae K.
Publication type:
Article
Kinome-Wide Virtual Screening by Multi-Task Deep Learning.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2538, doi. 10.3390/ijms25052538
By:
- Hu, Jiaming;
- Allen, Bryce K.;
- Stathias, Vasileios;
- Ayad, Nagi G.;
- Schürer, Stephan C.
Publication type:
Article
RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60031-8
By:
- Jermakowicz, Anna M.;
- Kurimchak, Alison M.;
- Johnson, Katherine J.;
- Bourgain-Guglielmetti, Florence;
- Kaeppeli, Simon;
- Affer, Maurizio;
- Pradhyumnan, Hari;
- Suter, Robert K.;
- Walters, Winston;
- Cepero, Maria;
- Duncan, James S.;
- Ayad, Nagi G.
Publication type:
Article

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