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Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36269-7
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- Publication type:
- Article
Genetic determinants of gut microbiota composition and bile acid profiles in mice.
- Published in:
- PLoS Genetics, 2019, v. 15, n. 8, p. 1, doi. 10.1371/journal.pgen.1008073
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- Publication type:
- Article
Zinc, insulin, and the liver: a ménage à trois.
- Published in:
- 2013
- By:
- Publication type:
- Opinion
Defending science education against intelligent design: a call to action.
- Published in:
- 2006
- By:
- Publication type:
- journal article
The Republican war on science.
- Published in:
- 2006
- By:
- Publication type:
- Book Review
Stearoyl-CoA Desaturase Deficiency, Hypercholesterolemia, Cholestasis, and Diabetes.
- Published in:
- Nutrition Reviews, 2007, v. 65, p. S35, doi. 10.1301/nr.2007.jun.S35-S38
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- Publication type:
- Article
Modeling Causality for Pairs of Phenotypes in System Genetics.
- Published in:
- Genetics, 2013, v. 193, n. 3, p. 1003, doi. 10.1534/genetics.112.147124
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- Publication type:
- Article
Quantile-Based Permutation Thresholds for Quantitative Trait Loci Hotspots.
- Published in:
- Genetics, 2012, v. 191, n. 4, p. 1355, doi. 10.1534/genetics.112.139451
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- Publication type:
- Article
Genome Scans for Transmission Ratio Distortion Regions in Mice.
- Published in:
- Genetics, 2012, v. 191, n. 1, p. 247, doi. 10.1534/genetics.111.135988
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- Publication type:
- Article
A Model Selection Approach for Expression Quantitative Trait Loci (eQTL) Mapping.
- Published in:
- Genetics, 2011, v. 187, n. 2, p. 611, doi. 10.1534/genetics.110.122796
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- Publication type:
- Article
Inferring Causal Phenotype Networks From Segregating Populations.
- Published in:
- Genetics, 2008, v. 179, n. 2, p. 1089, doi. 10.1534/genetics.107.085167
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- Publication type:
- Article
Selective Phenotyping for Increased Efficiency in Genetic Mapping Studies.
- Published in:
- Genetics, 2004, v. 168, n. 4, p. 2285, doi. 10.1534/genetics.104.027524
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- Publication type:
- Article
Dimension Reduction for Mapping mRNA Abundance as Quantitative Traits.
- Published in:
- Genetics, 2003, v. 164, n. 4, p. 1607, doi. 10.1093/genetics/164.4.1607
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- Publication type:
- Article
Getting biological about the genetics of diabetes.
- Published in:
- 2010
- By:
- Publication type:
- Opinion
Diabetes-linked SORCS1, a gamma-secretase substrate and regulator of Alzheimer APP metabolism, forms complexes with multiple Alzheimer-linked proteins (APP, PS1, BACE, VPS35, and SORLA)
- Published in:
- 2010
- By:
- Publication type:
- Abstract
High-maintenance proteins and hypertriglyceridemia.
- Published in:
- Nature Genetics, 2007, v. 39, n. 12, p. 1424, doi. 10.1038/ng1207-1424
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- Publication type:
- Article
Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.
- Published in:
- Nature Genetics, 2006, v. 38, n. 6, p. 688, doi. 10.1038/ng1796
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- Publication type:
- Article
The Collaborative Cross, a community resource for the genetic analysis of complex traits.
- Published in:
- 2004
- By:
- Publication type:
- Opinion
PGC-1a at the crossroads of type 2 diabetes.
- Published in:
- Nature Genetics, 2003, v. 34, n. 3, p. 244, doi. 10.1038/ng0703-244
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- Publication type:
- Article
Gastrointestinal hormones and the regulation of β-cell mass.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1212, n. 1, p. 41, doi. 10.1111/j.1749-6632.2010.05802.x
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- Publication type:
- Article
Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.
- Published in:
- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0282-y
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- Publication type:
- Article
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants.
- Published in:
- Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02450-8
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- Publication type:
- Article
Metabolic syndrome: from epidemiology to systems biology.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-11047-6
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- Publication type:
- Article
Identification of sample mix-ups and mixtures in microbiome data in Diversity Outbred mice.
- Published in:
- G3: Genes | Genomes | Genetics, 2021, v. 11, n. 11, p. 1, doi. 10.1093/g3journal/jkab308
- By:
- Publication type:
- Article
The Mouse Universal Genotyping Array: From Substrains to Subspecies.
- Published in:
- G3: Genes | Genomes | Genetics, 2016, v. 6, n. 2, p. 263, doi. 10.1534/g3.115.022087
- By:
- Publication type:
- Article
Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study.
- Published in:
- 2015
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- Publication type:
- Case Study
Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.
- Published in:
- FASEB Journal, 2008, v. 22, n. 10, p. 3581, doi. 10.1096/fj.08-111690
- By:
- Publication type:
- Article
Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin.
- Published in:
- PLoS Genetics, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.pgen.1010713
- By:
- Publication type:
- Article
Gene loci associated with insulin secretion in islets from non-diabetic mice.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.
- Published in:
- 2018
- By:
- Publication type:
- journal article
How do reducing equivalents increase insulin secretion?
- Published in:
- 2015
- By:
- Publication type:
- journal article
The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR.
- Published in:
- 2007
- By:
- Publication type:
- Correction Notice
The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR.
- Published in:
- Traffic, 2007, v. 8, n. 6, p. 718, doi. 10.1111/j.1600-0854.2007.00562.x
- By:
- Publication type:
- Article
Novel regulators of islet function identified from genetic variation in mouse islet Ca<sup>2+</sup> oscillations.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.88189
- By:
- Publication type:
- Article
SORCS1: A Novel Human Type 2 Diabetes Susceptibility Gene Suggested by the Mouse.
- Published in:
- Diabetes, 2007, v. 56, n. 7, p. 1922, doi. 10.2337/db06-1677
- By:
- Publication type:
- Article
Cholecystokinin Overexpression in Isolated Islets Promotes β-Cell Proliferation in a Cck1r- and Cck2r-Independent Manner.
- Published in:
- Diabetes, 2007, v. 56, p. A417
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- Publication type:
- Article
Loss of Stearoyl-CoA Desaturase-1 Improves Insulin Sensitivity in Lean Mice but Worsens Diabetes in Leptin-Deficient Obese Mice.
- Published in:
- Diabetes, 2007, v. 56, n. 5, p. 1228, doi. 10.2337/db06-1142
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- Publication type:
- Article
Distinguishing covariation from causation in diabetes: a lesson from the protein disulfide isomerase mRNA abundance trait.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Identification of major quantitative trait loci controlling body weight variation in ob/ob mice.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Distinguishing Covariation From Causation in Diabetes.
- Published in:
- Diabetes, 2004, v. 53, n. 1, p. 240, doi. 10.2337/diabetes.53.1.240
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- Publication type:
- Article
Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility.
- Published in:
- 2003
- By:
- Publication type:
- journal article
Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.
- Published in:
- 2000
- By:
- Publication type:
- journal article
Genetic Drivers of Pancreatic Islet Function.
- Published in:
- Genetics, 2018, v. 209, n. 1, p. 335, doi. 10.1534/genetics.118.300864
- By:
- Publication type:
- Article
Statistical Methods for Latent Class Quantitative Trait Loci Mapping.
- Published in:
- Genetics, 2017, v. 206, n. 3, p. 1309, doi. 10.1534/genetics.117.203885
- By:
- Publication type:
- Article
The Dissection of Expression Quantitative Trait Locus Hotspots.
- Published in:
- Genetics, 2016, v. 202, n. 4, p. 1563, doi. 10.1534/genetics.115.183624
- By:
- Publication type:
- Article
Genetic Architectures of Quantitative Variation in RNA Editing Pathways.
- Published in:
- Genetics, 2016, v. 202, n. 2, p. 787, doi. 10.1534/genetics.115.179481
- By:
- Publication type:
- Article
Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets.
- Published in:
- Genetics, 2015, v. 201, n. 3, p. 1253, doi. 10.1534/genetics.115.179432
- By:
- Publication type:
- Article
RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations.
- Published in:
- Genetics, 2014, v. 198, n. 1, p. 59, doi. 10.1534/genetics.114.165886
- By:
- Publication type:
- Article
Integrative Analysis of a Cross-Loci Regulation Network Identifies App as a Gene Regulating Insulin Secretion from Pancreatic Islets.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 12, p. 1, doi. 10.1371/journal.pgen.1003107
- By:
- Publication type:
- Article