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SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30088-y
By:
- Zhang, Wuji;
- Chua, Brendon Y.;
- Selva, Kevin J.;
- Kedzierski, Lukasz;
- Ashhurst, Thomas M.;
- Haycroft, Ebene R.;
- Shoffner-Beck, Suzanne K.;
- Hensen, Luca;
- Boyd, David F.;
- James, Fiona;
- Mouhtouris, Effie;
- Kwong, Jason C.;
- Chua, Kyra Y. L.;
- Drewett, George;
- Copaescu, Ana;
- Dobson, Julie E.;
- Rowntree, Louise C.;
- Habel, Jennifer R.;
- Allen, Lilith F.;
- Koay, Hui-Fern
Publication type:
Article
Zika virus encephalitis in immunocompetent mice is dominated by innate immune cells and does not require T or B cells.
Published in:
2019
By:
- Hayashida, Emina;
- Ling, Zheng Lung;
- Ashhurst, Thomas M.;
- Viengkhou, Barney;
- Jung, So Ri;
- Songkhunawej, Pattama;
- West, Phillip K.;
- King, Nicholas J. C.;
- Hofer, Markus J.
Publication type:
journal article
Using single-cell cytometry to illustrate integrated multi-perspective evaluation of clustering algorithms using Pareto fronts.
Published in:
Bioinformatics, 2021, v. 37, n. 14/15, p. 1972, doi. 10.1093/bioinformatics/btab038
By:
- Putri, Givanna H;
- Koprinska, Irena;
- Ashhurst, Thomas M;
- King, Nicholas J C;
- Read, Mark N
Publication type:
Article
TrackSOM: Mapping immune response dynamics through clustering of time‐course cytometry data.
Published in:
Cytometry. Part A, 2023, v. 103, n. 1, p. 54, doi. 10.1002/cyto.a.24668
By:
- Putri, Givanna H.;
- Chung, Jonathan;
- Edwards, Davis N.;
- Marsh‐Wakefield, Felix;
- Koprinska, Irena;
- Dervish, Suat;
- King, Nicholas J. C.;
- Ashhurst, Thomas M.;
- Read, Mark N.
Publication type:
Article
Cyt‐Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops.
Published in:
Cytometry. Part A, 2019, v. 95, n. 6, p. 598, doi. 10.1002/cyto.a.23777
By:
- Czechowska, Kamila;
- Lannigan, Joanne;
- Wang, Lili;
- Arcidiacono, Judith;
- Ashhurst, Thomas M.;
- Barnard, Ruth M.;
- Bauer, Steven;
- Bispo, Cláudia;
- Bonilla, Diana L.;
- Brinkman, Ryan R.;
- Cabanski, Maciej;
- Chang, Hyun‐Dong;
- Chakrabarti, Lina;
- Chojnowski, Grace;
- Cotleur, Bunny;
- Degheidy, Heba;
- Dela Cruz, Gelo V.;
- Eck, Steven;
- Elliott, John;
- Errington, Rachel
Publication type:
Article
Clodronate is not protective in lethal viral encephalitis despite substantially reducing inflammatory monocyte infiltration in the CNS.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1203561
By:
- Spiteri, Alanna G.;
- van Vreden, Caryn;
- Ashhurst, Thomas M.;
- Niewold, Paula;
- King, Nicholas J. C.
Publication type:
Article
The cytokines interleukin-6 and interferon-α induce distinct microglia phenotypes.
Published in:
2022
By:
- West, Phillip K.;
- McCorkindale, Andrew N.;
- Guennewig, Boris;
- Ashhurst, Thomas M.;
- Viengkhou, Barney;
- Hayashida, Emina;
- Jung, So Ri;
- Butovsky, Oleg;
- Campbell, Iain L.;
- Hofer, Markus J.
Publication type:
journal article
High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease.
Published in:
2021
By:
- Spiteri, Alanna G.;
- Terry, Rachel L.;
- Wishart, Claire L.;
- Ashhurst, Thomas M.;
- Campbell, Iain L.;
- Hofer, Markus J.;
- King, Nicholas J. C.
Publication type:
journal article
CD8 + T Cells Mediate Lethal Lung Pathology in the Absence of PD-L1 and Type I Interferon Signalling following LCMV Infection.
Published in:
Viruses (1999-4915), 2024, v. 16, n. 3, p. 390, doi. 10.3390/v16030390
By:
- Spiteri, Alanna G.;
- Suprunenko, Tamara;
- Cutts, Erin;
- Suen, Andrew;
- Ashhurst, Thomas M.;
- Viengkhou, Barney;
- King, Nicholas J. C.;
- Hofer, Markus J.
Publication type:
Article
SuperCellCyto: enabling efficient analysis of large scale cytometry datasets.
Published in:
Genome Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13059-024-03229-3
By:
- Putri, Givanna H.;
- Howitt, George;
- Marsh-Wakefield, Felix;
- Ashhurst, Thomas M.;
- Phipson, Belinda
Publication type:
Article
Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles.
Published in:
Science Translational Medicine, 2014, v. 6, n. 219, p. 1, doi. 10.1126/scitranslmed.3007563
By:
- Getts, Daniel R.;
- Terry, Rachael L.;
- Getts, Meghann Teague;
- Deffrasnes, Celine;
- Müller, Marcus;
- van Vreden, Caryn;
- Ashhurst, Thomas M.;
- Chami, Belal;
- McCarthy, Derrick;
- Huiling Wu;
- Jin Ma;
- Martin, Aaron;
- Shae, Lonnie D.;
- Witting, Paul;
- Kansas, Geoffrey S.;
- Kühn, Joachim;
- Hafezi, Wali;
- Campbell, Iain L.;
- Reilly, David;
- Say, Jana
Publication type:
Article
A unique cytotoxic CD4<sup>+</sup> T cell‐signature defines critical COVID‐19.
Published in:
Clinical & Translational Immunology, 2023, v. 12, n. 8, p. 1, doi. 10.1002/cti2.1463
By:
- Baird, Sarah;
- Ashley, Caroline L;
- Marsh‐Wakefield, Felix;
- Alca, Sibel;
- Ashhurst, Thomas M;
- Ferguson, Angela L;
- Lukeman, Hannah;
- Counoupas, Claudio;
- Post, Jeffrey J;
- Konecny, Pamela;
- Bartlett, Adam;
- Martinello, Marianne;
- Bull, Rowena A;
- Lloyd, Andrew;
- Grey, Alice;
- Hutchings, Owen;
- Palendira, Umaimainthan;
- Britton, Warwick J;
- Steain, Megan;
- Triccas, James A
Publication type:
Article
Circulating effector γδ T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals.
Published in:
Immunology & Cell Biology, 2023, v. 101, n. 4, p. 321, doi. 10.1111/imcb.12623
By:
- von Borstel, Anouk;
- Nguyen, Thi HO;
- Rowntree, Louise C;
- Ashhurst, Thomas M;
- Allen, Lilith F;
- Howson, Lauren J;
- Holmes, Natasha E;
- Smibert, Olivia C;
- Trubiano, Jason A;
- Gordon, Claire L;
- Cheng, Allen C;
- Kent, Stephen J;
- Rossjohn, Jamie;
- Kedzierska, Katherine;
- Davey, Martin S
Publication type:
Article
A high‐dimensional cytometry atlas of peripheral blood over the human life span.
Published in:
Immunology & Cell Biology, 2022, v. 100, n. 10, p. 805, doi. 10.1111/imcb.12594
By:
- Jalali, Sedigheh;
- Harpur, Christopher M;
- Piers, Adam T;
- Auladell, Maria;
- Perriman, Louis;
- Li, Shuo;
- An, Kim;
- Anderson, Jeremy;
- Berzins, Stuart P;
- Licciardi, Paul V;
- Ashhurst, Thomas M;
- Konstantinov, Igor E;
- Pellicci, Daniel G
Publication type:
Article
Peripheral B‐cell dysregulation is associated with relapse after long‐term quiescence in patients with multiple sclerosis.
Published in:
Immunology & Cell Biology, 2022, v. 100, n. 6, p. 453, doi. 10.1111/imcb.12552
By:
- Marsh‐Wakefield, Felix;
- Juillard, Pierre;
- Ashhurst, Thomas M;
- Juillard, Annette;
- Shinko, Diana;
- Putri, Givanna H;
- Read, Mark N;
- McGuire, Helen M;
- Byrne, Scott N;
- Hawke, Simon;
- Grau, Georges E
Publication type:
Article
Defective Inflammatory Monocyte Development in IRF8-Deficient Mice Abrogates Migration to the West Nile Virus-Infected Brain.
Published in:
Journal of Innate Immunity, 2014, v. 7, n. 1, p. 102, doi. 10.1159/000365972
By:
- Terry, Rachael L.;
- Deffrasnes, Celine;
- Getts, Daniel R.;
- Minten, Carsten;
- van Vreden, Caryn;
- ashhurst, Thomas M.;
- Getts, Meghann T.;
- Xie, Rui Dan Vicki;
- Campbell, Iain L.;
- King, Nicholas J.C.
Publication type:
Article
Contribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infection.
Published in:
PLoS Pathogens, 2020, v. 16, n. 4, p. 1, doi. 10.1371/journal.ppat.1008525
By:
- Jung, So Ri;
- Ashhurst, Thomas M.;
- West, Phillip K.;
- Viengkhou, Barney;
- King, Nicholas J. C.;
- Campbell, Iain L.;
- Hofer, Markus J.
Publication type:
Article

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