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Evaluation of artemisinins for the treatment of acute myeloid leukemia.
Published in:
2016
By:
- Drenberg, Christina;
- Buaboonnam, Jassada;
- Orwick, Shelley;
- Hu, Shuiying;
- Li, Lie;
- Fan, Yiping;
- Shelat, Anang;
- Guy, R.;
- Rubnitz, Jeffrey;
- Baker, Sharyn;
- Drenberg, Christina D;
- Orwick, Shelley J;
- Shelat, Anang A;
- Guy, R Kiplin;
- Baker, Sharyn D
Publication type:
journal article
Searching for New Antimalarial Therapeutics amongst Known Drugs.
Published in:
Chemical Biology & Drug Design, 2006, v. 67, n. 6, p. 409, doi. 10.1111/j.1747-0285.2006.00391.x
By:
- Weisman, Jennifer L.;
- Liou, Ally P.;
- Shelat, Anang A.;
- Cohen, Fred E.;
- Guy, R. Kiplin;
- DeRisi, Joseph L.
Publication type:
Article
Discovery of Trypanocidal Compounds by Whole Cell HTS of Trypanosoma brucei.
Published in:
Chemical Biology & Drug Design, 2006, v. 67, n. 5, p. 355, doi. 10.1111/j.1747-0285.2006.00389.x
By:
- Mackey, Zachary B.;
- Baca, Arthur M.;
- Mallari, Jeremy P.;
- Apsel, Beth;
- Shelat, Anang;
- Hansell, Elizabeth J.;
- Chiang, Peter K.;
- Wolff, Brian;
- Guy, Kiplin R.;
- Williams, Janice;
- McKerrow, James H.
Publication type:
Article
BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action.
Published in:
Scientific Reports, 2016, p. 25523, doi. 10.1038/srep25523
By:
- Twarog, Nathaniel R.;
- Stewart, Elizabeth;
- Hammill, Courtney Vowell;
- A. Shelat, Anang
Publication type:
Article
Discovery of Small Molecules that Inhibit the Disordered Protein, p27<sup>Kip1</sup>.
Published in:
Scientific Reports, 2015, p. 15686, doi. 10.1038/srep15686
By:
- Iconaru, Luigi I.;
- Ban, David;
- Bharatham, Kavitha;
- Ramanathan, Arvind;
- Zhang, Weixing;
- Shelat, Anang A.;
- Zuo, Jian;
- Kriwacki, Richard W.
Publication type:
Article
The net electrostatic potential and hydration of ABCG2 affect substrate transport.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40610-5
By:
- Gose, Tomoka;
- Aitken, Heather M.;
- Wang, Yao;
- Lynch, John;
- Rampersaud, Evadnie;
- Fukuda, Yu;
- Wills, Medb;
- Baril, Stefanie A.;
- Ford, Robert C.;
- Shelat, Anang;
- Mara, Megan L. O';
- Schuetz, John D.
Publication type:
Article
Identification of Small Molecule Activators of BMP Signaling.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059045
By:
- Vrijens, Karen;
- Lin, Wenwei;
- Cui, Jimmy;
- Farmer, Dana;
- Low, Jonathan;
- Pronier, Elodie;
- Zeng, Fu-Yue;
- Shelat, Anang A.;
- Guy, Kiplin;
- Taylor, Michael R.;
- Chen, Taosheng;
- Roussel, Martine F.
Publication type:
Article
A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09917-0
By:
- Drenberg, Christina D.;
- Shelat, Anang;
- Dang, Jinjun;
- Cotton, Anitria;
- Orwick, Shelley J.;
- Li, Mengyu;
- Jeon, Jae Yoon;
- Fu, Qiang;
- Buelow, Daelynn R.;
- Pioso, Marissa;
- Hu, Shuiying;
- Inaba, Hiroto;
- Ribeiro, Raul C.;
- Rubnitz, Jeffrey E.;
- Gruber, Tanja A.;
- Guy, R. Kiplin;
- Baker, Sharyn D.
Publication type:
Article
Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 12, p. 1, doi. 10.1371/journal.pntd.0006157
By:
- Ortiz, Diana;
- Guiguemde, W. Armand;
- Hammill, Jared T.;
- Carrillo, Angela K.;
- Chen, Yizhe;
- Connelly, Michele;
- Stalheim, Kayla;
- Elya, Carolyn;
- Johnson, Alex;
- Min, Jaeki;
- Shelat, Anang;
- Smithson, David C.;
- Yang, Lei;
- Zhu, Fangyi;
- Guy, R. Kiplin;
- Landfear, Scott M.
Publication type:
Article
Chemical genetics of Plasmodium falciparum.
Published in:
Nature, 2010, v. 465, n. 7296, p. 311, doi. 10.1038/nature09099
By:
- Guiguemde, W. Armand;
- Shelat, Anang A.;
- Bouck, David;
- Duffy, Sandra;
- Crowther, Gregory J.;
- Davis, Paul H.;
- Smithson, David C.;
- Connelly, Michele;
- Clark, Julie;
- Zhu, Fangyi;
- Jiménez-Díaz, María B.;
- Martinez, María S.;
- Wilson, Emily B.;
- Tripathi, Abhai K.;
- Gut, Jiri;
- Sharlow, Elizabeth R.;
- Bathurst, Ian;
- Mazouni, Farah El;
- Fowble, Joseph W.;
- Forquer, Isaac
Publication type:
Article
A critical evaluation of methods to interpret drug combinations.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61923-1
By:
- Twarog, Nathaniel R.;
- Connelly, Michele;
- Shelat, Anang A.
Publication type:
Article
DIPG-05. A RATIONAL COMBINATION STRATEGY TARGETING ATM KINASE IN PEDIATRIC HIGH-GRADE GLIOMA.
Published in:
Neuro-Oncology, 2019, v. 21, p. ii69, doi. 10.1093/neuonc/noz036.026
By:
- Xie, Jia;
- He, Chen;
- Bianski, Brandon;
- Twarog, Nathaniel;
- Baker, Suzanne;
- Shelat, Anang;
- Tinkle, Christopher
Publication type:
Article
An Evolutionarily Conserved Residue in ABCG2 Regulates the Transport Cycle and Inhibitor Activity.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5185
By:
- Gose, Tomoka;
- Das, Sourav;
- Wang, Yao;
- Lynch, John;
- Fukuda, Yu;
- Wills, Medb;
- Baril, Stefanie;
- Shelat, Anang;
- Schuetz, John D.
Publication type:
Article
ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket.
Published in:
FASEB Journal, 2020, v. 34, n. 4, p. 4890, doi. 10.1096/fj.201902338RR
By:
- Gose, Tomoka;
- Shafi, Talha;
- Fukuda, Yu;
- Das, Sourav;
- Wang, Yao;
- Allcock, Alice;
- Gavan McHarg, Ailsa;
- Lynch, John;
- Chen, Taosheng;
- Tamai, Ikumi;
- Shelat, Anang;
- Ford, Robert C.;
- Schuetz, John D.
Publication type:
Article
Metabolic regulation of apoptosis via coenzyme A mediated activation of CaMKII (577.2).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.577.2
By:
- McCoy, Francis;
- Darbandi, Rashid;
- Lee, Hoi Chang;
- Bharatham, Kavitha;
- Moldoveanu, Tudor;
- Grace, Christy;
- Dodd, Keela;
- Lin, Wenwei;
- Chen, Si‐Ing;
- Tangallapally, Rajendra;
- Kurokawa, Manabu;
- Lee, Richard;
- Shelat, Anang;
- Chen, Taosheng;
- Green, Douglas;
- Harris, Robert;
- Lin, Sue‐Hwa;
- Fissore, Rafael;
- Colbran, Roger;
- Nutt, Leta
Publication type:
Article
Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.
Published in:
Angewandte Chemie, 2021, v. 133, n. 51, p. 26867, doi. 10.1002/ange.202108848
By:
- Min, Jaeki;
- Mayasundari, Anand;
- Keramatnia, Fatemeh;
- Jonchere, Barbara;
- Yang, Seung Wook;
- Jarusiewicz, Jamie;
- Actis, Marisa;
- Das, Sourav;
- Young, Brandon;
- Slavish, Jake;
- Yang, Lei;
- Li, Yong;
- Fu, Xiang;
- Garrett, Shalandus H.;
- Yun, Mi‐Kyung;
- Li, Zhenmei;
- Nithianantham, Stanley;
- Chai, Sergio;
- Chen, Taosheng;
- Shelat, Anang
Publication type:
Article
Poly ADP Ribose Polymerase (PARP) Inhibitors and Their Role in the Treatment of Pediatric Acute Myeloid Leukemia.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2018, v. 18, p. S199, doi. 10.1016/j.clml.2018.07.047
By:
- Kamens, Jennifer;
- Seth, Aman;
- Cottton, Anitria;
- Shelat, Anang;
- Gruber, Tanja
Publication type:
Article
Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 51, p. 26663, doi. 10.1002/anie.202108848
By:
- Min, Jaeki;
- Mayasundari, Anand;
- Keramatnia, Fatemeh;
- Jonchere, Barbara;
- Yang, Seung Wook;
- Jarusiewicz, Jamie;
- Actis, Marisa;
- Das, Sourav;
- Young, Brandon;
- Slavish, Jake;
- Yang, Lei;
- Li, Yong;
- Fu, Xiang;
- Garrett, Shalandus H.;
- Yun, Mi‐Kyung;
- Li, Zhenmei;
- Nithianantham, Stanley;
- Chai, Sergio;
- Chen, Taosheng;
- Shelat, Anang
Publication type:
Article
Optimization of a Non-Radioactive High-Throughput Assay for Decarboxylase Enzymes.
Published in:
Assay & Drug Development Technologies, 2010, v. 8, n. 2, p. 175, doi. 10.1089/adt.2009.0249
By:
- David C. Smithson;
- Anang A. Shelat;
- Jeffrey Baldwin;
- Margaret A. Phillips;
- R. Kiplin Guy
Publication type:
Article
Cheminformatics aspects of high throughput screening: from robots to models: symposium summary.
Published in:
Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 5, p. 443, doi. 10.1007/s10822-013-9646-6
By:
- Jane Tseng, Y.;
- Martin, Eric;
- Bologa, Cristian;
- Shelat, Anang
Publication type:
Article
Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 6, p. 599, doi. 10.1002/psp4.12627
By:
- Husband, Hillary R.;
- Campagne, Olivia;
- He, Chen;
- Zhu, Xiaoyan;
- Bianski, Brandon M.;
- Baker, Suzanne J.;
- Shelat, Anang A.;
- Tinkle, Christopher L.;
- Stewart, Clinton F.
Publication type:
Article
Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis.
Published in:
PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149439
By:
- Twarog, Nathaniel R.;
- Low, Jonathan A.;
- Currier, Duane G.;
- Miller, Greg;
- Chen, Taosheng;
- Shelat, Anang A.
Publication type:
Article
Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1313-7
By:
- Jin Zhang;
- Bowling, John J.;
- Smithson, David;
- Clark, Julie;
- Jacob, Melissa R.;
- Khan, Shabana I.;
- Tekwani, Babu L.;
- Connelly, Michele;
- Samoylenko, Vladimir;
- Ibrahim, Mohamed A.;
- Zaki, Mohamed A.;
- Mei Wang;
- Hester, John P.;
- Ying Tu;
- Jeffries, Cynthia;
- Twarog, Nathaniel;
- Shelat, Anang A.;
- Walker, Larry A.;
- Muhammad, Ilias;
- Guy, R. Kiplin
Publication type:
Article
MAIP: a web service for predicting blood‐stage malaria inhibitors.
Published in:
Journal of Cheminformatics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13321-021-00487-2
By:
- Bosc, Nicolas;
- Felix, Eloy;
- Arcila, Ricardo;
- Mendez, David;
- Saunders, Martin R.;
- Green, Darren V. S.;
- Ochoada, Jason;
- Shelat, Anang A.;
- Martin, Eric J.;
- Iyer, Preeti;
- Engkvist, Ola;
- Verras, Andreas;
- Duffy, James;
- Burrows, Jeremy;
- Gardner, J. Mark F.;
- Leach, Andrew R.
Publication type:
Article
MAIP: a web service for predicting blood‐stage malaria inhibitors.
Published in:
Journal of Cheminformatics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13321-021-00487-2
By:
- Bosc, Nicolas;
- Felix, Eloy;
- Arcila, Ricardo;
- Mendez, David;
- Saunders, Martin R.;
- Green, Darren V. S.;
- Ochoada, Jason;
- Shelat, Anang A.;
- Martin, Eric J.;
- Iyer, Preeti;
- Engkvist, Ola;
- Verras, Andreas;
- Duffy, James;
- Burrows, Jeremy;
- Gardner, J. Mark F.;
- Leach, Andrew R.
Publication type:
Article
Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors.
Published in:
Journal of Neuro-Oncology, 2016, v. 126, n. 2, p. 225, doi. 10.1007/s11060-015-1965-0
By:
- Morfouace, Marie;
- Nimmervoll, Birgit;
- Boulos, Nidal;
- Patel, Yogesh;
- Shelat, Anang;
- Freeman, Burgess;
- Robinson, Giles;
- Wright, Karen;
- Gajjar, Amar;
- Stewart, Clinton;
- Gilbertson, Richard;
- Roussel, Martine
Publication type:
Article
Erratum: BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action.
Published in:
Scientific Reports, 2018, p. 46970, doi. 10.1038/srep46970
By:
- Twarog, Nathaniel R.;
- Stewart, Elizabeth;
- Hammill, Courtney Vowell;
- Shelat, Anang A.
Publication type:
Article
Publisher Correction: The net electrostatic potential and hydration of ABCG2 affect substrate transport.
Published in:
2024
By:
- Gose, Tomoka;
- Aitken, Heather M.;
- Wang, Yao;
- Lynch, John;
- Rampersaud, Evadnie;
- Fukuda, Yu;
- Wills, Medb;
- Baril, Stefanie A.;
- Ford, Robert C.;
- Shelat, Anang;
- O'Mara, Megan L.;
- Schuetz, John D.
Publication type:
Correction Notice
Scaffold composition and biological relevance of screening libraries.
Published in:
2007
By:
- Shelat, Anang A.;
- Guy, R. Kiplin
Publication type:
Editorial
High-throughput assays for promiscuous inhibitors.
Published in:
Nature Chemical Biology, 2005, v. 1, n. 3, p. 146, doi. 10.1038/nchembio718
By:
- Feng, Brian Y.;
- Shelat, Anang;
- Doman, Thompson N.;
- Guy, R. Kip;
- Shoichet, Brian K.
Publication type:
Article

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