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Structure–property relationship study of the HPLC enantioselective retention of neuroprotective 7‐[(1‐alkylpiperidin‐3‐yl)methoxy]coumarin derivatives on an amylose‐based chiral stationary phase.
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- Journal of Separation Science, 2018, v. 41, n. 6, p. 1376, doi. 10.1002/jssc.201701442
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- Article
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c- Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways.
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- Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 10, p. 1380, doi. 10.1111/jphp.12438
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- Article
Investigation on the antiplatelet activity of pyrrolo[3,2- c]pyridine-containing compounds.
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- Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 3, p. 323, doi. 10.1211/002235702676
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- Article
In Vivo Investigation of (2-Hydroxypropyl)-β-cyclodextrin-Based Formulation of Spironolactone in Aqueous Solution for Paediatric Use.
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- Pharmaceutics, 2022, v. 14, n. 4, p. N.PAG, doi. 10.3390/pharmaceutics14040780
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- Article
Nature-Inspired 1-Phenylpyrrolo[2,1- a ]isoquinoline Scaffold for Novel Antiproliferative Agents Circumventing P-Glycoprotein-Dependent Multidrug Resistance.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 539, doi. 10.3390/ph17040539
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- Article
Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer's Disease.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 1, p. 54, doi. 10.3390/ph16010054
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- Article
Chemical and Biological Evaluation of Novel 1 H -Chromeno[3,2- c ]pyridine Derivatives as MAO Inhibitors Endowed with Potential Anticancer Activity.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 7724, doi. 10.3390/ijms24097724
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- Article
Lipophilicity Plays a Major Role in Modulating the Inhibition of Monoamine Oxidase B by 7-Substituted Coumarins.
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- Chemistry & Biodiversity, 2006, v. 3, n. 2, p. 134, doi. 10.1002/cbdv.200690017
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- Article
Synthesis and Biological Evaluation of Dantrolene‐Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases.
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- ChemMedChem, 2021, v. 16, n. 18, p. 2807, doi. 10.1002/cmdc.202100209
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- Article
Evaluation of Water‐Soluble Mannich Base Prodrugs of 2,3,4,5‐Tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as Multitarget‐Directed Agents for Alzheimer's Disease.
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- ChemMedChem, 2021, v. 16, n. 3, p. 589, doi. 10.1002/cmdc.202000583
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- Article
Scouting around 1,2,3,4‐Tetrahydrochromeno[3,2‐c]pyridin‐10‐ones for Single‐ and Multitarget Ligands Directed towards Relevant Alzheimer's Targets.
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- ChemMedChem, 2020, v. 15, n. 20, p. 1947, doi. 10.1002/cmdc.202000468
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- Article
A New Class of 1‐Aryl‐5,6‐dihydropyrrolo[2,1‐a]isoquinoline Derivatives as Reversers of P‐Glycoprotein‐Mediated Multidrug Resistance in Tumor Cells.
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- ChemMedChem, 2018, v. 13, n. 15, p. 1588, doi. 10.1002/cmdc.201800177
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- Article
The natural mutation by deletion of Lys9 in the thrombin A-chain affects the p K<sub>a</sub> value of catalytic residues, the overall enzyme's stability and conformational transitions linked to Na<sup>+</sup> binding.
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- FEBS Journal, 2006, v. 273, n. 1, p. 159, doi. 10.1111/j.1742-4658.2005.05052.x
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- Article
Synthesis and Monoamine Oxidase Inhibitory Activity of 3-Substituted 5 H-Indeno[1,2- c]pyridazines.
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- Helvetica Chimica Acta, 1993, v. 76, n. 5, p. 1956, doi. 10.1002/hlca.19930760514
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- Article
Electronic and Conformational Effects on the Lipophilicity of Isomers and Analogs of the Neurotoxin 1-Methyl-4-phenylpyridinium (MPP<sup>+</sup>).
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- Helvetica Chimica Acta, 1991, v. 74, n. 2, p. 290, doi. 10.1002/hlca.19910740205
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- Article
A Stereoselective, Multicomponent Catalytic Carbonylative Approach to a New Class of α,β-Unsaturated γ-Lactam Derivatives.
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- Catalysts (2073-4344), 2021, v. 11, n. 2, p. 227, doi. 10.3390/catal11020227
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- Article
Sensory-Motor Modulations of EEG Event-Related Potentials Reflect Walking-Related Macro-Affordances.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 11, p. 1506, doi. 10.3390/brainsci11111506
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- Article
Mind the Gap! A Journey towards Computational Toxicology.
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- Molecular Informatics, 2016, v. 35, n. 8/9, p. 294, doi. 10.1002/minf.201501017
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- Article
Radiosynthesis and whole‐body distribution in mice of a <sup>18</sup>F‐labeled azepino[4,3‐b]indole‐1‐one derivative with multimodal activity for the treatment of Alzheimer's disease.
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- Archiv der Pharmazie, 2024, v. 357, n. 3, p. 1, doi. 10.1002/ardp.202300491
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- Article
2-Benzazepine Nitrones Protect Dopaminergic Neurons against 6-Hydroxydopamine-Induced Oxidative Toxicity.
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- Archiv der Pharmazie, 2012, v. 345, n. 8, p. 598, doi. 10.1002/ardp.201200007
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- Article
Investigation on Novel E/Z 2-Benzylideneindan-1-One-Based Photoswitches with AChE and MAO-B Dual Inhibitory Activity.
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- Molecules, 2023, v. 28, n. 15, p. 5857, doi. 10.3390/molecules28155857
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- Article
Synthesis of Novel Benzo[ b ][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors.
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- Molecules, 2023, v. 28, n. 4, p. 1662, doi. 10.3390/molecules28041662
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- Article
Synthesis of Isomeric 3-Benzazecines Decorated with Endocyclic Allene Moiety and Exocyclic Conjugated Double Bond and Evaluation of Their Anticholinesterase Activity.
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- Molecules, 2022, v. 27, n. 19, p. 6276, doi. 10.3390/molecules27196276
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- Article
Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases.
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- Molecules, 2022, v. 27, n. 13, p. 4269, doi. 10.3390/molecules27134269
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- Article
Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1 H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase.
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- Separations (2297-8739), 2022, v. 9, n. 1, p. 7, doi. 10.3390/separations9010007
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- Article
Bridging repair of the abdominal wall in a rat experimental model. Comparison between uncoated and polyethylene oxide-coated equine pericardium meshes.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63886-9
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- Article
Walking-related locomotion is facilitated by the perception of distant targets in the extrapersonal space.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46384-5
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- Article
Foot-related/walking macro-affordances are implicitly activated and preferentially guided by the framing distance of the environmental layout.
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- Psychological Research, 2023, v. 87, n. 3, p. 787, doi. 10.1007/s00426-022-01692-w
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- Article
Small Molecules for the Treatment of Long-COVID-Related Vascular Damage and Abnormal Blood Clotting: A Patent-Based Appraisal.
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- Viruses (1999-4915), 2024, v. 16, n. 3, p. 450, doi. 10.3390/v16030450
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- Article
Evaluation of Novel Guanidino-Containing Isonipecotamide Inhibitors of Blood Coagulation Factors against SARS-CoV-2 Virus Infection.
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- Viruses (1999-4915), 2022, v. 14, n. 8, p. 1730, doi. 10.3390/v14081730
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- Article
Physicochemical properties and antimicrobial activity of new spirocyclic thieno[2,3- d]pyrimidin-4(3 H)-one derivatives.
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- Chemistry of Heterocyclic Compounds, 2017, v. 53, n. 3, p. 357, doi. 10.1007/s10593-017-2057-1
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- Article
A Critical Appraisal of the Protective Activity of Polyphenolic Antioxidants against Iatrogenic Effects of Anticancer Chemotherapeutics #.
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- Antioxidants, 2024, v. 13, n. 1, p. 133, doi. 10.3390/antiox13010133
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- Article
Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease.
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- Antioxidants, 2022, v. 11, n. 9, p. 1631, doi. 10.3390/antiox11091631
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- Article
Tandem Cleavage of Hydrogenated β- and γ-Carbolines − New Practical Synthesis of Tetrahydroazocino[4,5-b]indoles and Tetrahydroazocino[5,4-b]indoles Showing Acetylcholinesterase Inhibitory Activity.
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- European Journal of Organic Chemistry, 2004, v. 2004, n. 14, p. 3128, doi. 10.1002/ejoc.200400107
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- Article
Short-term anti-remodeling effects of gliflozins in diabetic patients with heart failure and reduced ejection fraction: an explainable artificial intelligence approach.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1175606
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- Article
Substituent effects on the enantioselective retention of anti-HIV 5-aryl-Δ<sup>2</sup>-1,2,4-oxadiazolines on R, R-DACH-DNB chiral stationary phase.
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- Chirality, 1996, v. 8, n. 8, p. 556, doi. 10.1002/(SICI)1520-636X(1996)8:8<556::AID-CHIR4>3.0.CO;2-7
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- Article
Enantiomeric resolution of sulfoxides on a DACH-DNB chiral stationary phase: A quantitative structure-enantioselective retention relationship (QSERR) study.
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- Chirality, 1993, v. 5, n. 7, p. 527, doi. 10.1002/chir.530050709
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- Article
First-in-Class Isonipecotamide-Based Thrombin and Cholinesterase Dual Inhibitors with Potential for Alzheimer Disease.
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- Molecules, 2021, v. 26, n. 17, p. 5208, doi. 10.3390/molecules26175208
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- Article
Deciphering the Interactions of Bioactive Compounds in Selected Traditional Medicinal Plants against Alzheimer's Diseases via Pharmacophore Modeling, Auto-QSAR, and Molecular Docking Approaches.
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- Molecules, 2021, v. 26, n. 7, p. 1996, doi. 10.3390/molecules26071996
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- Article
One-Pot Synthesis of Novel Multisubstituted 1-Alkoxyindoles.
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- Molecules, 2021, v. 26, n. 5, p. 1466, doi. 10.3390/molecules26051466
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- Article
Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer's Disease and Parkinson's Disease Treatment (2011–2020).
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- Molecules, 2021, v. 26, n. 5, p. 1202, doi. 10.3390/molecules26051202
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- Article
Homobivalent Lamellarin-Like Schiff Bases: In Vitro Evaluation of Their Cancer Cell Cytotoxicity and Multitargeting Anti-Alzheimer's Disease Potential.
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- Molecules, 2021, v. 26, n. 2, p. 359, doi. 10.3390/molecules26020359
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- Article
First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease.
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- Molecules, 2021, v. 26, n. 1, p. 80, doi. 10.3390/molecules26010080
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- Article
Bioresearch of New 1 H -pyrrolo[3,4-c]pyridine-1,3(2 H)-diones.
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- Molecules, 2020, v. 25, n. 24, p. 5883, doi. 10.3390/molecules25245883
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- Article
Pharmacophore Modeling and 3D-QSAR Study of Indole and Isatin Derivatives as Antiamyloidogenic Agents Targeting Alzheimer's Disease †.
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- Molecules, 2020, v. 25, n. 23, p. 5773, doi. 10.3390/molecules25235773
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- Article
Novel Antiproliferative Biphenyl Nicotinamide: NMR Metabolomic Study of its Effect on the MCF-7 Cell in Comparison with Cisplatin and Vinblastine.
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- Molecules, 2020, v. 25, n. 15, p. 3502, doi. 10.3390/molecules25153502
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- Article
Exploiting the Indole Scaffold to Design Compounds Binding to Different Pharmacological Targets †.
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- Molecules, 2020, v. 25, n. 10, p. 2331, doi. 10.3390/molecules25102331
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- Article
5-(1H-Indol-3-ylmethylene)-4-oxo-2-thioxothiazolidin-3-yl)alkancarboxylic Acids as Antimicrobial Agents: Synthesis, Biological Evaluation, and Molecular Docking Studies.
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- Molecules, 2020, v. 25, n. 8, p. 1964, doi. 10.3390/molecules25081964
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- Article
Chasing ChEs-MAO B Multi-Targeting 4-Aminomethyl-7-Benzyloxy-2H-Chromen-2-ones.
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- Molecules, 2019, v. 24, n. 24, p. 4507, doi. 10.3390/molecules24244507
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- Article
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer's Disease.
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- Molecules, 2019, v. 24, n. 23, p. 4298, doi. 10.3390/molecules24234298
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- Article