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Selection of Nanobodies that Block the Enzymatic and Cytotoxic Activities of the Binary Clostridium Difficile Toxin CDT.
- Published in:
- Scientific Reports, 2015, p. 7850, doi. 10.1038/srep07850
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- Publication type:
- Article
Inhibition of Arp2/3 Complex after ADP-Ribosylation of Arp2 by Binary Clostridioides Toxins.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 22, p. 3661, doi. 10.3390/cells11223661
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- Publication type:
- Article
Clostridioides difficile Binary Toxin Is Recognized by the Toll-Like Receptor 2/6 Heterodimer to Induce a Nuclear Factor-κB Response.
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- 2022
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- Publication type:
- Journal Article
Human peptide α‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT.
- Published in:
- FASEB Journal, 2020, v. 34, n. 5, p. 6244, doi. 10.1096/fj.201902816R
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- Publication type:
- Article
Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.
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- FASEB Journal, 2019, v. 33, n. 4, p. 5755, doi. 10.1096/fj.201802453R
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- Publication type:
- Article
Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway.
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- FASEB Journal, 2019, v. 33, n. 4, p. 4883, doi. 10.1096/fj.201801440R
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- Publication type:
- Article
Intracellular plasma membrane guidance of Photorhabdus asymbiotica toxin is crucial for cell toxicity.
- Published in:
- FASEB Journal, 2015, v. 29, n. 7, p. 2789, doi. 10.1096/fj.14-269381
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- Publication type:
- Article
Substrate specificity of Pasteurella multocida toxin for α subunits of heterotrimeric G proteins.
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- FASEB Journal, 2013, v. 27, n. 2, p. 832, doi. 10.1096/fj.12-213900
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- Publication type:
- Article
Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival.
- Published in:
- Journal of Neurochemistry, 2006, v. 97, n. 4, p. 957, doi. 10.1111/j.1471-4159.2006.03802.x
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- Publication type:
- Article
Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons.
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- Journal of Neurochemistry, 2005, v. 94, n. 4, p. 1025, doi. 10.1111/j.1471-4159.2005.03252.x
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- Publication type:
- Article
Role of actin filaments in endothelial cell-cell adhesion and membrane stability under fluid shear stress.
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- Pflügers Archiv: European Journal of Physiology, 2001, v. 442, n. 5, p. 675, doi. 10.1007/s004240100589
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- Publication type:
- Article
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P[sub 3] and polarity during neutrophil chemotaxis.
- Published in:
- Journal of Cell Biology, 2003, v. 160, n. 3, p. 375, doi. 10.1083/jcb.200208179
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- Publication type:
- Article
The chaperone Hsp90 and PPIases of the cyclophilin and FKBP families facilitate membrane translocation of P hotorhabdus luminescens ADP-ribosyltransferases.
- Published in:
- Cellular Microbiology, 2014, v. 16, n. 4, p. 490, doi. 10.1111/cmi.12228
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- Publication type:
- Article
FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells.
- Published in:
- Cellular Microbiology, 2012, v. 14, n. 8, p. 1193, doi. 10.1111/j.1462-5822.2012.01788.x
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- Publication type:
- Article
Domain organization of Legionella effector SetA.
- Published in:
- Cellular Microbiology, 2012, v. 14, n. 6, p. 852, doi. 10.1111/j.1462-5822.2012.01761.x
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- Publication type:
- Article
Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen.
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- Cellular Microbiology, 2011, v. 13, n. 3, p. 359, doi. 10.1111/j.1462-5822.2010.01539.x
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- Publication type:
- Article
Pasteurella multocida toxin is a potent activator of anti-apoptotic signalling pathways.
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- Cellular Microbiology, 2010, v. 12, n. 8, p. 1174, doi. 10.1111/j.1462-5822.2010.01462.x
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- Publication type:
- Article
Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos.
- Published in:
- Nature Communications, 2015, v. 6, n. 7, p. 7807, doi. 10.1038/ncomms8807
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- Publication type:
- Article
The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.
- Published in:
- Nature Communications, 2014, v. 5, n. 12, p. 5887, doi. 10.1038/ncomms6887
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- Publication type:
- Article
Lu/BCAM Adhesion Glycoprotein Is a Receptor for <i>Escherichia coli</i> Cytotoxic Necrotizing Factor 1 (CNF1).
- Published in:
- PLoS Pathogens, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.ppat.1003884
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- Publication type:
- Article
<i>Pasteurella Multocida</i> Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gα<sub>q/11</sub> - p63RhoGEF - RhoA Axis
- Published in:
- PLoS Pathogens, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.ppat.1003385
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- Publication type:
- Article
Bacterial cytotoxins: targeting eukaryotic switches.
- Published in:
- Nature Reviews Microbiology, 2005, v. 3, n. 5, p. 397, doi. 10.1038/nrmicro1150
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- Publication type:
- Article
Semaphorins or Frizzled –it is the receptor that direct the action of clostridial glucosylating toxins.
- Published in:
- Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41392-020-00307-3
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- Publication type:
- Article
Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.
- Published in:
- Molecular Microbiology, 2012, v. 84, n. 6, p. 1189, doi. 10.1111/j.1365-2958.2012.08078.x
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- Publication type:
- Article
Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.
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- Molecular Microbiology, 2011, v. 79, n. 6, p. 1643, doi. 10.1111/j.1365-2958.2011.07549.x
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- Publication type:
- Article
Bacillus sphaericus mosquitocidal toxin (MTX) and pierisin: the enigmatic offspring from the family of ADP-ribosyltransferases.
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- Molecular Microbiology, 2006, v. 62, n. 3, p. 621, doi. 10.1111/j.1365-2958.2006.05401.x
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- Publication type:
- Article
Actin Involvement in Exocytosis from PC12 Cells: Studies on the Influence of Botulinum C2 Toxin on Stimulated Noradrenaline Release.
- Published in:
- Journal of Neurochemistry, 1989, v. 52, n. 2, p. 370, doi. 10.1111/j.1471-4159.1989.tb09131.x
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- Publication type:
- Article
A bacterial toxin catalyzing tyrosine glycosylation of Rho and deamidation of G<sub>q</sub> and G<sub>i</sub> proteins.
- Published in:
- Nature Structural & Molecular Biology, 2013, v. 20, n. 11, p. 1273, doi. 10.1038/nsmb.2688
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- Publication type:
- Article
Antibodies Directed Against GalNAc- and GlcNAc-OTyrosine Posttranslational Modifications -- a New Tool for Glycoproteomic Detection.
- Published in:
- Chemistry - A European Journal, 2023, v. 29, n. 29, p. 1, doi. 10.1002/chem.202300392
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- Publication type:
- Article
A nucleotide regulatory site for somatostatin inhibition of adenylate cyclase in S49 lymphoma cells.
- Published in:
- Nature, 1983, v. 303, n. 5913, p. 177, doi. 10.1038/303177a0
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- Publication type:
- Article
Rho-glucosylating Clostridium difficile toxins A and B: new insights into structure and function.
- Published in:
- Glycobiology, 2007, v. 17, n. 4, p. 15
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- Publication type:
- Article
Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05850-w
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- Publication type:
- Article
Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
- Published in:
- PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008530
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- Publication type:
- Article
Aminoacyl-tRNA-Charged Eukaryotic Elongation Factor 1A Is the Bona Fide Substrate for Legionella pneumophila Effector Glucosyltransferases.
- Published in:
- PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029525
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- Publication type:
- Article
Clostridial Glucosylating Toxins Enter Cells via Clathrin-Mediated Endocytosis.
- Published in:
- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010673
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- Publication type:
- Article
Mechanism of Tc toxin action revealed in molecular detail.
- Published in:
- Nature, 2014, v. 508, n. 7494, p. 61, doi. 10.1038/nature13015
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- Publication type:
- Article
A syringe-like injection mechanism in Photorhabdus luminescens toxins.
- Published in:
- Nature, 2013, v. 495, n. 7442, p. 520, doi. 10.1038/nature11987
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- Publication type:
- Article
Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT.
- Published in:
- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01204
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- Publication type:
- Article
The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB.
- Published in:
- Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.784856
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- Publication type:
- Article
Involvement of N‐glycans in binding of Photorhabdus luminescens Tc toxin.
- Published in:
- Cellular Microbiology, 2021, v. 23, n. 8, p. 1, doi. 10.1111/cmi.13326
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- Publication type:
- Article
Photorhabdus luminescensTc toxin is inhibited by the protease inhibitor MG132 and activated by protease cleavage resulting in increased binding to target cells.
- Published in:
- Cellular Microbiology, 2019, v. 21, n. 3, p. N.PAG, doi. 10.1111/cmi.12978
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- Publication type:
- Article
Actin ADP-ribosylation at Threonine148 by Photorhabdus luminescens toxin TccC3 induces aggregation of intracellular F-actin.
- Published in:
- Cellular Microbiology, 2017, v. 19, n. 1, p. n/a, doi. 10.1111/cmi.12636
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- Publication type:
- Article
Bacterial glycosyltransferase toxins.
- Published in:
- Cellular Microbiology, 2015, v. 17, n. 12, p. 1752, doi. 10.1111/cmi.12533
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- Publication type:
- Article
A systemic P asteurella multocida toxin aggravates cardiac hypertrophy and fibrosis in mice.
- Published in:
- Cellular Microbiology, 2015, v. 17, n. 9, p. 1320, doi. 10.1111/cmi.12436
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- Publication type:
- Article
The actin and Rho-modifying toxins PTC3 and PTC5 of P hotorhabdus luminescens: enzyme characterization and induction of MAL/ SRF-dependent transcription.
- Published in:
- Cellular Microbiology, 2015, v. 17, n. 4, p. 579, doi. 10.1111/cmi.12386
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- Publication type:
- Article
Rundown of somatodendritic N-methyl- D-aspartate (NMDA) receptor channels in rat hippocampal neurones: evidence for a role of the small GTPase RhoA.
- Published in:
- British Journal of Pharmacology, 1999, v. 127, n. 5, p. 1060, doi. 10.1038/sj.bjp.0702643
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- Publication type:
- Article
Crystal structure of the C3bot–RalA complex reveals a novel type of action of a bacterial exoenzyme.
- Published in:
- EMBO Journal, 2005, v. 24, n. 20, p. 3670, doi. 10.1038/sj.emboj.7600813
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- Publication type:
- Article
C3 exoenzymes, novel insights into structure and action of Rho-ADP-ribosylating toxins.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2007, v. 374, n. 5/6, p. 347, doi. 10.1007/s00210-006-0113-y
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- Publication type:
- Article
The uptake machinery of clostridial actin ADP-ribosylating toxins – a cell delivery system for fusion proteins and polypeptide drugs.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2002, v. 366, n. 6, p. 501, doi. 10.1007/s00210-002-0626-y
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- Publication type:
- Article
Cytotoxic effects by microinjection of ADP-ribosylated skeletal muscle G-actin in PtK2 cells in the absence of Clostridium perfringens iota toxin.
- Published in:
- Medical Microbiology & Immunology, 1996, v. 184, n. 4, p. 175, doi. 10.1007/BF02456132
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- Publication type:
- Article